Catalytic And Biocatalytic Methods For The Efficient Synthesis Of Biologically Relevant Non Proteinogenic Amino Acids
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Catalytic And Biocatalytic Methods For The Efficient Synthesis Of Biologically Relevant Non Proteinogenic Amino Acids
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Author : Anke Lemke
language : en
Publisher: Cuvillier Verlag
Release Date : 2014-04-29
Catalytic And Biocatalytic Methods For The Efficient Synthesis Of Biologically Relevant Non Proteinogenic Amino Acids written by Anke Lemke and has been published by Cuvillier Verlag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-29 with Science categories.
Non-proteinogenic amino acids are often important constituents of biologically potent natural products. The synthesis of these amino acids is often time-consuming, non-trivial and not sustainable. Thus, the central topic of this work was the formation of unusual amino acid structures by biocatalytic and catalytic methods. For the elucidation of the biosynthetic pathway of Streptomyces-produced muraymycins and related natural products, a ‘biosynthetic tool kit’ was compiled and prepared. This does not only comprehend the completed synthesis of deuterium-labeled compounds, such as (3R)- and (3S)-3-hydroxy-[5-2H]-l-arginine and other potential intermediates with a nucleosidic structure, but it also includes the development of fermentation methodology including the possibility to detect the muraymycin derivatives by LC MS. Furthermore, different synthetic routes with catalytic key steps for the preparation of the non-proteinogenic amino acid enduracididine were investigated.
Modification Of Polymers
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Author : Charles E. Carraher
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Modification Of Polymers written by Charles E. Carraher and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The sheer volume of topics which could have been included under our general title prompted us to make some rather arbitrary decisions about content. Modification by irradiation is not included because the activity in this area is being treated elsewhere. We have chosen to emphasize chemical routes to modification and have striven to pre sent as balanced a representation of current activity as time and page count permit. Industrial applications, both real and potential, are included. Where appropriate, we have encouraged the contributors to include review material to help provide the reader with adequate context. The initial chapter is a review from a historical perspective of polymer modification and contains an extensive bibliography. The remainder of the book is divided into four general areas: Reactions and Preparation of Copolymers Reactions and Preparation of Block and Graft Copolymers Modification Through Condensation Reactions Applications The chemical modification of homopolymers such as polyvinylchlo ride, polyethylene, poly(chloroalkylene sulfides), polysulfones, poly chloromethylstyrene, polyisobutylene, polysodium acrylate, polyvinyl alcohol, polyvinyl chloroformate, sulfonated polystyrene; block and graft copolymers such as poly(styrene-block-ethylene-co-butylene block-styrene), poly(I,4-polybutadiene-block ethylene oxide), star chlorine-telechelic polyisobutylene, poly(isobutylene-co-2,3-dimethyl- 1,3-butadiene), poly(styrene-co-N-butylmethacrylate); cellulose, dex tran and inulin, is described.
Recent Developments In Applied Microbiology And Biochemistry
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Author : Viswanath Buddolla
language : en
Publisher: Academic Press
Release Date : 2020-10-15
Recent Developments In Applied Microbiology And Biochemistry written by Viswanath Buddolla and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-15 with Medical categories.
Recent Developments in Applied Microbiology and Biochemistry, Vol. 2, provides a comprehensive treatment and understanding on application oriented microbial concepts, giving readers insights into recent developments in microbial biotechnology and medical, agricultural and environmental microbiology. Discusses microbial proteome analyses and their importance in medical microbiology Explores emerging trends in the prevention of current global health problems, such as cancer, obesity and immunity Shows recent approaches in the production of novel enzymes from environmental samples by enrichment culture and metagenomics approaches Guides readers through the status and recent developments in analytical methods for the detection of foodborne microorganisms
Biocatalysis For Practitioners
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Author : Gonzalo de Gonzalo
language : en
Publisher: John Wiley & Sons
Release Date : 2021-07-19
Biocatalysis For Practitioners written by Gonzalo de Gonzalo and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-19 with Science categories.
This reference book originates from the interdisciplinary research cooperation between academia and industry. In three distinct parts, latest results from basic research on stable enzymes are explained and brought into context with possible industrial applications. Downstream processing technology as well as biocatalytic and biotechnological production processes from global players display the enormous potential of biocatalysts. Application of "extreme" reaction conditions (i.e. unconventional, such as high temperature, pressure, and pH value) - biocatalysts are normally used within a well defined process window - leads to novel synthetic effects. Both novel enzyme systems and the synthetic routes in which they can be applied are made accessible to the reader. In addition, the complementary innovative process technology under unconventional conditions is highlighted by latest examples from biotech industry.
Industrial Biocatalysis
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Author : Peter Grunwald
language : en
Publisher: CRC Press
Release Date : 2014-12-11
Industrial Biocatalysis written by Peter Grunwald and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-12-11 with Medical categories.
Biocatalysis has become an essential tool in the chemical industry and is the core of industrial biotechnology, also known as white biotechnology, making use of biocatalysts in terms of enzymes or whole cells in chemical processes as an alternative to chemical catalysts. This shift can be seen in the many areas of daily life where biocatalysts-with
Biocatalytic Process Optimization
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Author : Chia-Hung Kuo
language : en
Publisher: MDPI
Release Date : 2021-01-14
Biocatalytic Process Optimization written by Chia-Hung Kuo and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-01-14 with Science categories.
Biocatalysis is very appealing to the industry because it allows, in principle, the synthesis of products not accessible by chemical synthesis. Enzymes are very effective, as are precise biocatalysts, as they are enantioselective, with mild reaction conditions and green chemistry. Biocatalysis is currently widely used in the pharmaceutical industry, food industry, cosmetic industry, and textile industry. This includes enzyme production, biocatalytic process development, biotransformation, enzyme engineering, immobilization, the synthesis of fine chemicals and the recycling of biocatalysts. One of the most challenging problems in biocatalysis applications is process optimization. This Special Issue shows that an optimized biocatalysis process can provide an environmentally friendly, clean, highly efficient, low cost, and renewable process for the synthesis and production of valuable products. With further development and improvements, more biocatalysis processes may be applied in the future.
Enzyme Biocatalysis
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Author : Andrés Illanes
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-06-19
Enzyme Biocatalysis written by Andrés Illanes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-19 with Technology & Engineering categories.
This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or potential, written by experts in the respective ?elds. We sincerely hope that this book will represent an element in the toolbox of gr- uate students in applied biology and chemical and biochemical engineering and also of undergraduate students with formal training in organic chemistry, biochemistry, thermodynamics and chemical reaction kinetics. Beyond that, the book pretends also to illustrate the potential of biocatalytic processes with case studies in the ?eld of organic synthesis, which we hope will be of interest for the academia and prof- sionals involved in R&D&I. If some of our young readers are encouraged to engage or persevere in their work in biocatalysis this will certainly be our more precious reward.
Asymmetric Synthesis And Application Of Alpha Amino Acids
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Author : Vadim A Soloshonok
language : en
Publisher: American Chemical Society
Release Date : 2009-07-09
Asymmetric Synthesis And Application Of Alpha Amino Acids written by Vadim A Soloshonok and has been published by American Chemical Society this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-07-09 with Language Arts & Disciplines categories.
This volume presents the most recent and comprehensive collection of reviews on methodological developments in the field of alpha-amino acids.
Modern Biocatalysis
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Author : Gavin Williams
language : en
Publisher: Royal Society of Chemistry
Release Date : 2018-05-31
Modern Biocatalysis written by Gavin Williams and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-31 with Science categories.
The synergy between synthetic biology and biocatalysis is emerging as an important trend for future sustainable processes. This book reviews all modern and novel techniques successfully implemented in biocatalysis, in an effort to provide better performing enzymatic systems and novel biosynthetic routes to (non-)natural products. This includes the use of molecular techniques in protein design and engineering, construction of artificial metabolic pathways, and application of computational methods for enzyme discovery and design. Stress is placed on current ‘hot’ topics in biocatalysis, where recent advances in research are defining new grounds in enzyme-catalyzed processes. With contributions from leading academics around the world, this book makes a ground-breaking contribution to this progressive field and is essential reading for graduates and researchers investigating (bio)catalysis, enzyme engineering, chemical biology, and synthetic biology.
Activity Based Protein Profiling
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Author : Benjamin F. Cravatt
language : en
Publisher: Springer
Release Date : 2019-01-25
Activity Based Protein Profiling written by Benjamin F. Cravatt and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-25 with Medical categories.
This volume provides a collection of contemporary perspectives on using activity-based protein profiling (ABPP) for biological discoveries in protein science, microbiology, and immunology. A common theme throughout is the special utility of ABPP to interrogate protein function and small-molecule interactions on a global scale in native biological systems. Each chapter showcases distinct advantages of ABPP applied to diverse protein classes and biological systems. As such, the book offers readers valuable insights into the basic principles of ABPP technology and how to apply this approach to biological questions ranging from the study of post-translational modifications to targeting bacterial effectors in host-pathogen interactions.