Cell Biology Of The Axon
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Cell Biology Of The Axon
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Author : Edward Koenig
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-01
Cell Biology Of The Axon written by Edward Koenig and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-01 with Science categories.
Recent years have witnessed striking advances in research on axons at a cellular level that substantially impact our current understanding of axonal biology. Newer findings and their ramifications are critically reviewed in the 16 chapters of this volume by authors highly qualified by virtue of their scientific contributions to research areas they know and write about. Five basic areas (I to V) germane to axonal biology are highlighted, beginning with (I) signaling interactions mediating myelination, and differentiation of axonal membrane domains; (IIa) issues surrounding organization and transport dynamics of neurofilaments in axons, (IIb) mechanisms regulating microtubule organization and dynamics, misregulation of which causes axonal degeneration, and (IIc) the roles actin binding proteins play in regulating organization and functions of the actin filament system in mature and growing axons; (IIIa) myosin motor proteins and cargoes intrinsic to the axon compartment, (IIIb) mitochondrial transport motors, and imperatives governing transport dynamics and directional delivery, (IIIc) mechanisms mediating retrograde signaling associated with NGF’s role in trophic-dependent neuronal survival, and (IIId) potential for impaired subcellular targeting of a -synuclein as a mechanism for accumulation of Lewy body inclusions in synucleinopathies; (IVa) occurrence and organization of discrete ribosome-containing domains in axons, (IVb) endogenous mRNAs, classes of proteins translated locally, and RNP trafficking in axons, (IVc) importance of locally synthesized nuclear encoded mitochondrial proteins for maintenance, function and survival of axons, (IVd) occurrence of RNA trafficking from glial cells to axons, and significance glial RNA transcripts may play in expression in axons and axon terminals, (IVe) RNA trafficking and localization of RNA transcripts in axonal growth cones, and signaling pathways that modulate local protein synthesis for directional elongation, and (IVf) genetic and molecular defects underlying spinal muscular atrophy, and roles that SMN gene product plays as a molecular chaperone in mRNA transport and translation; (Va) injury-induced local synthesis of a protein forming a retrograde signaling complex in axons to stimulate regeneration, and (Vb) endogenous and exogenous factors that condition axonal regenerative capacity in PNS and CNS, including injury-induced activation of specific genes governing regeneration. Emergent complexities revealed in this volume compel a major revision in the traditional conceptual model of the axon’s intrinsic makeup and capacities.
The Neuronal Cytoskeleton Motor Proteins And Organelle Trafficking In The Axon
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Author :
language : en
Publisher: Academic Press
Release Date : 2016-01-12
The Neuronal Cytoskeleton Motor Proteins And Organelle Trafficking In The Axon written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-12 with Science categories.
The Neuronal Cytoskeleton, Motor Proteins, and Organelle Trafficking in the Axon, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in neuronal cells, and includes sections on such topics as actin transport in axons and neurofilament transport. Covers an increasingly appreciated field in cell biology Includes both established and new technologies Contributed by experts in the field
Axons
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Author : Hiro Yamamoto
language : en
Publisher: Nova Science Publishers
Release Date : 2014-02-10
Axons written by Hiro Yamamoto and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-10 with Axons categories.
Axons are nerve fibres that typically conduct electrical impulses away from the neuron's cell body. The function of the axon is to transmit information to different neurons, muscles and glands. In this book, the authors discuss the cell biology, molecular dynamics and role in neural repair and rehabilitation of axons. Topics include the traumatic retraction of living neural processes and their inhibitions; water translocation from the axoplasm into the glioplasm during reactive reorganisation of myelinated nerve fibres; problems and mechanisms in axonal afterdischarges; the putative role of axon cytoskeleton protein in MS repair; microtubules as a potential therapeutic target for the treatment of neurodegenerative diseases; morphometrical and molecular biological analyses of facial nerves in healthy adults and patients with facial nerve palsy; intrinsic axon growth potential; and sensory axonal guidance by chemorepulsive and chemoattractive cues in higher vertebrates.
The Neuron
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Author : Irwin B. Levitan
language : en
Publisher: Oxford University Press, USA
Release Date : 2015
The Neuron written by Irwin B. Levitan and has been published by Oxford University Press, USA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.
Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.
Cellular Dynamics Of The Neuron
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Author : Samuel H. Barondes
language : en
Publisher: Academic Press
Release Date : 2014-05-10
Cellular Dynamics Of The Neuron written by Samuel H. Barondes and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.
Cellular Dynamics of the Neuron covers advances in the study of the cellular dynamics of the neuron. The book discusses the synthesis and transport of the neuroplasm, as well as the synthesis, transport, and action of neurotransmitters. The text also describes the functional implications of synaptic ultrastructure and the morphological and biochemical correlates of neuronal plasticity. Cell biologists, neurobiologists, cell pathologists, molecular biologists, and physiologists will find the book invaluable.
Molecular Biology Of The Neuron
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Author : R. Wayne Davies
language : en
Publisher: Oxford University Press
Release Date : 2004-04-08
Molecular Biology Of The Neuron written by R. Wayne Davies and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-04-08 with Medical categories.
This book is a valuable compendium of up-to-date reviews of neuronal molecular biology by leading researchers in the field. It covers all aspects of neuron structure and function, with the emphasis on genetic and molecular analysis.
Neurons Methods And Applications For The Cell Biologist
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Author :
language : en
Publisher: Elsevier
Release Date : 2003-10-02
Neurons Methods And Applications For The Cell Biologist written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-10-02 with Science categories.
Neurons: Methods and Applications for the Cell Biologist lays out numerous simple techniques for growing and carrying out experiments with many varieties of neurons. Subjects include peripheral and central neurons from vertebrate and invertebrate sources, as well as neuron-like cell lines. It also explains recent advances in our ability to introduce exogenous proteins and genes to neurons in culture. Procedures for successful protein infiltration, biolistic transfection, electroporation, and viral transgenic methods in neurons are also presented. Contains culture methodology for more than a dozen types of CNS and PNS neurons Includes most recent and reliable techniques from expert practitioners for specific experimental applications Addresses the latest strategies for transfecting neurons
Neural Cell Biology
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Author : Cheng Wang
language : en
Publisher: CRC Press
Release Date : 2017-06-26
Neural Cell Biology written by Cheng Wang and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-26 with Medical categories.
This book delineates how systems biology, pharmacogenomic, and behavioral approaches, as applied to neurodevelopmental toxicology, provide a structure to arrange information in a biological model. The text reviews and discusses approaches that can be used as effective tools to dissect mechanisms underlying pharmacological and toxicological phenomena associated with the exposure to drugs or environmental toxicants during development. The book intends to elaborate functional outcomes of component-to-component relationships using rodent and nonhuman primate in vitro and in vivo models that allow for the directional and quantitative description of the complete organism in response to environmental perturbations. In addition, attention has also been directed to some of the more recent methodologies, including genomics, proteomics and metabolomics, applied in the evolutionary neurobiological field.
Cell Biology Of Brain
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Author : William Eric Watson
language : en
Publisher: Chapman & Hall
Release Date : 1976
Cell Biology Of Brain written by William Eric Watson and has been published by Chapman & Hall this book supported file pdf, txt, epub, kindle and other format this book has been release on 1976 with Brain categories.
Axonal Regeneration In The Mammalian Central Nervous System
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Author : Dorothy E. Oorschot
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Axonal Regeneration In The Mammalian Central Nervous System written by Dorothy E. Oorschot and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.