Cell Biology Of Trauma
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Cell Biology Of Trauma
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Author : John J. Lemasters
language : en
Publisher: CRC Press
Release Date : 2020-08-16
Cell Biology Of Trauma written by John J. Lemasters and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-16 with Science categories.
This unique book presents an approach to viewing trauma. It examines the cellular consequences of trauma at a molecular level and provides new insights into the treatment of traumatic injury, based on cellular responses. The current of trauma research is reviewed, previously unpublished information on the topic is presented, and research directions are included.
The Biology Of Trauma
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Author : Aimie Apigian
language : en
Publisher: Simon and Schuster
Release Date : 2025-07-22
The Biology Of Trauma written by Aimie Apigian and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-07-22 with Psychology categories.
This groundbreaking book breaks down the latest research to reveal how trauma impacts our bodies on a cellular level and offers an empowering path to whole-body healing. Today, we know more about mental health than ever before, but traditional medicine still mistakes subtle signs of trauma for stress, anxiety, or chronic disease—sometimes even retraumatizing patients with outdated and misguided methods. Treatment plans that focus on the mind are only addressing the downstream effects. Likewise, common medical approaches to manage symptoms fail to explore root causes and promote genuine recovery. If we want to truly heal, we need to understand trauma as something happening inside of the body—not as a singular external event. Gaining clarity on how our bodies hold onto experiences, impacting both our physical health and our ability to maintain healthy behaviors and relationships, is crucial. That’s where Dr. Aimie Apigian’s integrative, revolutionary approach comes in. With a decade of clinical research, approachable storytelling, and real-life examples, The Biology of Trauma will show you: How the body absorbs scarring experiences and overwhelm Ways to identify commonly overlooked trauma symptoms like lethargy, fogginess, and unexplained worry Recognize how emotional pain stored in the body affects overall health on a cellular level, even for people with functionally successful lives Prevent trauma-induced changes in your biology that suppress the cycle of recovery Work with your nervous system to safely heal—without risk of retraumatization Perfect for both individuals seeking personal growth and health professionals improving their practice, The Biology of Trauma will help you gain deep insights into your own mind, body, and healing journey.
Cell Injury
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Author : Raphael Carl Lee
language : en
Publisher:
Release Date : 2005
Cell Injury written by Raphael Carl Lee and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Medical categories.
When cells are damaged, as often occurs during trauma and metabolic stress, a highly evolved cell healing process follows that was designed to enhance cell survival or remove irreparably injured cells. Following injury, cells attempt to seal breaks in their membranes, chaperone removal or refolding of altered proteins, repair damaged DNA, or if necessary commit to programmed cell death. When cell injury is too extensive to permit reparative responses, acute cellular necrosis or apoptosis can result. Understanding injury at the subcellular organelle and molecular levels is essential for development of new therapeutic strategies and for optimal management of injured victims. In this volume, various modes of injury that can occur are described, as well as the basic molecular healing responses and pathways of metabolic survival or death.
The Biology Of Early Life Stress
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Author : Jennie G. Noll
language : en
Publisher: Springer
Release Date : 2018-06-14
The Biology Of Early Life Stress written by Jennie G. Noll and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-14 with Psychology categories.
This innovative collection extends the emerging field of stress biology to examine the effects of a substantial source of early-life stress: child abuse and neglect. Research findings across endocrinology, immunology, neuroscience, and genomics supply new insights into the psychological variables associated with adversity in children and its outcomes. These compelling interdisciplinary data add to a promising model of biological mechanisms involved in individual resilience amid chronic maltreatment and other trauma. At the same time, these results also open out distinctive new possibilities for serving vulnerable children and youth, focusing on preventing, intervening in, and potentially even reversing the effects of chronic early trauma. Included in the coverage: Biological embedding of child maltreatment Toward an adaptation-based approach to resilience Developmental traumatology: brain development and maltreated children with and without PTSD Childhood maltreatment and pediatric PTSD: abnormalities in threat neural circuitry An integrative temporal framework for psychological resilience The Biology of Early Life Stress is important reading for child maltreatment researchers; clinical psychologists; educators in counseling, psychology, trauma, and nursing; physicians; and state- and federal-level policymakers. Advocates, child and youth practitioners, and clinicians in general will find it a compelling resource.
Brain Injury
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Author : Robert S.B. Clark
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Brain Injury written by Robert S.B. Clark and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
Brain Injury is the second volume in the book series, Molecular and Cellular Biology of Critical Care Medicine. In this volume, a group of internationally regarded experts in important areas of neuroscience and neurointensive care research address the molecular and cellular basis of acute brain injury. This text covers acute brain injury within a context relevant to the care of patients with critical neurologic injuries such as cardiac arrest, trauma and stroke. It includes recent data pertaining to established pathways such as neurotransmission, exitotoxicity, ionic-mechanisms, oxidative stress, inflammation, and cerebral vascular injury. In addition, rapidly developing areas such as cell signaling, adenosine pharmacology, apoptosis, mitochondrial dysfunction, neurocytoskeletal changes, and the role of trophic factors are reviewed from the level of in vitro modeling to human data. Other topics covered that are highly clinically relevant include the effect of genetic background and gender differences in outcome after brain injury, preconditioning, and the effects of currently used anesthetics and sedative agents in patients with brain injury.
Host Defense Dysfunction In Trauma Shock And Sepsis
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Author : Eugen Faist
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Host Defense Dysfunction In Trauma Shock And Sepsis written by Eugen Faist and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
This book presents a unique overview of all aspects of host defense alterations under stressful conditions. It is based on the most important contributions given at the "2nd International Congress on the Immune Consequences of Trauma, Shock, and Sepsis-Mechanisms and Therapeutic Approaches," which was held in Munich under the auspices of the most distinguished scientific societies involved in this field (Society of Critical Care Medicine, European Society of Intensive Care Medicine, Societe Internationale de Chirurgie, Surgical Infection Society, Surgical Infection Society Europe, European Society for Surgical Research, International Society for Burn Injury, American Association for the Surgery of Trauma, and National Institutes of Health). Since the first conference of this kind in 1988, new information from basic studies and clinical trials has provided exciting and novel insights into the immune dysfunctions accom panying trauma, shock, and sepsis. The volume is divided into 18 parts presenting the structural background of trauma-induced alterations of immune and imflammatory mechanisms as well as the currently discussed therapeutic interventions designed to restore or maintain normal host defenses following major injury. Introducing the general theme of the book is a summary of the essential keystones of trauma and sepsis-related immune deficits. Discussions of the progress in trauma care brought through better understanding of the cell biology of injury and of the major clinical factors that influence host defense integrity in operative medicine provide a setting for understanding the wide array of detailed information that is presented thereafter.
Molecular And Cellular Aspects Of Shock And Trauma
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Author : Allan M. Lefer
language : en
Publisher:
Release Date : 1983
Molecular And Cellular Aspects Of Shock And Trauma written by Allan M. Lefer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Medical categories.
Mechanisms Of Secondary Brain Damage In Cerebral Ischemia And Trauma
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Author : Alexander Baethmann
language : en
Publisher: Springer
Release Date : 2012-02-22
Mechanisms Of Secondary Brain Damage In Cerebral Ischemia And Trauma written by Alexander Baethmann and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-22 with Medical categories.
The publication of the Vth International Symposium 1995 on "Mechanisms of Secondary Brain Damage" in Mauls/ltaly is a collection of focused reviews reaching from novel molecular- and cell biological findings to aspects of clinical management in head injury and cerebral ischemia. A specific purpose of these series of meetings introduced in 1984 is for an exchange on problems of mutual interest by international high ranking experts from the basic sciences and related clinical disciplines, such as intensive care medicine, neurology, or neurosurgery. The present volume covers three major areas: (a) Molecular and cell biological mechanisms including inflammation (b) Novel findings on mechanisms and treatment in cerebral ischemia (c) Secondary processes in head injury, regeneration and treatment Molecular-and cell biology is currently attracting attention towards activation of genomic processes associated with the demise of cells referred to as "programmed cell death" and "apoptosis" which, actually, might be distinguished from each other. Thus, the phenomenon of delayed neuronal death in selectively vulnerable brain areas following brief interruption of blood flow is scrutinized as to the contribution of the activation of suicide genes. The physiological role of such a response, among others, is removal of surplus neurons during ontogenesis of the brain. Yet, evidence is accumulating that similar mechanisms playa role in cerebral ischemia, probably also trauma, where nerve-and other cells demonstrate features of apoptosis. Observations on protection of neurons by administration of protein synthesis inhibitors in cerebral ischemia provide more direct support.
Neurobiology Of Spinal Cord Injury
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Author : Robert G. Kalb
language : en
Publisher: Humana Press
Release Date : 2010-10-28
Neurobiology Of Spinal Cord Injury written by Robert G. Kalb and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-28 with Medical categories.
Distinguished researchers review the latest scientific understanding of spinal cord injury (SCI), focusing on the mechanisms causing paralysis after spinal cord trauma, the molecular determinants of neural regeneration, and methods for improving damaged function. The authors examine the role of intracellular Ca2+ in neuronal death, the possibility of spinal learning, growth-promoting molecules for regenerating neurons, and the biochemistry and cell biology of microtubules. Among the treatment possibilities discussed are cell transplantation strategies beyond the use of fetal spinal cord tissue, remyelination in spinal cord demyelination models, high steroid therapy immediately after SCI, and the mixed use of anti- and proinflammatories. Comprehensive and highly promising, Neurobiology of Spinal Cord Injury summarizes and integrates the great progress that has been made in understanding and combating the paralysis that follows spinal cord injury.
Translational Research In Traumatic Brain Injury
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Author : Daniel Laskowitz
language : en
Publisher: CRC Press
Release Date : 2016-04-21
Translational Research In Traumatic Brain Injury written by Daniel Laskowitz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-21 with Medical categories.
Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the developme