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Cell Death In Reproductive Physiology


Cell Death In Reproductive Physiology
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Cell Death In Reproductive Physiology


Cell Death In Reproductive Physiology
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Author : Jonathan L. Tilly
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cell Death In Reproductive Physiology written by Jonathan L. Tilly and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The regulation of cell death in various reproductive tissues, as in other ma jor organ systems of the body, has become a focal point of research activity in many laboratories over the past few years. As such, the need for a "for mal" meeting to highlight recent work in this field, as well as to integrate knowledge from other sources (such as investigators working on cell death in cancer and immune function) in the broad context of identifying con served pathways that coordinate life-and-death decisions in diverse cell types, became apparent. Therefore, the goals of the Scientific Committee of the International Symposium on Cell Death in Reproductive Physiology, spon sored by Serono Symposia USA, were already predetermined by this need. Simply stated, we sought to bring together for the first time a select cohort of reproductive biologists and cell death researchers, many but not all cho sen based on their pioneering efforts in elucidating the fundamental aspects of apoptosis in reproductive and nonreproductive tissues, as a means to re view the current status of the field, foster new ideas, and promote scientific collaborations. In the ensuing chapters of this book, summaries of work dis cussed at the meeting are presented to emphasize both the diversity and the similarities in the occurrence and regulation of apoptosis in tissues of the male and female reproductive systems.



Apoptosis And Reproduction


Apoptosis And Reproduction
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Author :
language : en
Publisher:
Release Date : 1997

Apoptosis And Reproduction written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with Apoptosis categories.




Control Of Programmed Cell Death By Gcn 1


Control Of Programmed Cell Death By Gcn 1
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Author : Yoon Andrew Cho-Park
language : en
Publisher:
Release Date : 2022

Control Of Programmed Cell Death By Gcn 1 written by Yoon Andrew Cho-Park and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with categories.


In the present study/thesis, we have discovered potentially a novel translational control mechanism of programmed cell death by GCN-1, pending further molecular studies. Contrary to conventional wisdom, this control occurs in a GCN-2 and Integrated Stress Response pathway-independent manner, providing a non-canonical function to GCN-1. The present study also potentially provides further mechanistic understanding of the poorly understood biological phenomenon of germline programmed cell death; a biological process that initiates death to nurture life. The knowledge presented herein could help further understand human female reproductive physiology in order to potentially extend reproductive lifespan and mitigate oocyte loss and sterility caused by environmental stressors, such as radiation and chemotherapy.



The Biology Of Death


The Biology Of Death
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Author : André Klarsfeld
language : en
Publisher: Cornell University Press
Release Date : 2004

The Biology Of Death written by André Klarsfeld and has been published by Cornell University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.


Why do we die? Do all living creatures share this fate? Is the body's slow degradation with the passage of time unavoidable, or can the secrets of longevity be unlocked? Over the past two decades, scientists studying the workings of genes and cells have uncovered some of the clues necessary to solve these mysteries. In this fascinating and accessible book, two neurobiologists share the often-surprising findings from that research, including the possibility that aging and natural death may not be forever a certainty for most living beings. André Klarsfeld and Frédéric Revah discuss in detail the latest scientific findings and views on death and longevity. They challenge many popular assumptions, such as the idea that the death of individual organisms serves to rejuvenate species or that death and sexual reproduction are necessarily linked. Finally, they describe current experimental approaches to postpone natural death in lower organisms as well as in mammals. Are all organisms that survive until late in life condemned to a "natural" death, as a consequence of aging, even if they live in a well-protected, supportive environment? The variability of the adult life span--from a few hours for some insects to more than a millennium for the sequoia and thirteen times that for certain wild berry bushes--challenges the notion that death is unavoidable. Evolutionary theory helps explain why and how some species have achieved biological mechanisms that seemingly allow them to resist time. Death cannot be understood without looking into cells--the essential building blocks of life. Intriguingly, at the level of cells, death is not always an accident; it is often programmed as an indispensable aspect of life, which benefits the organism as a whole.



Plant Cell Death Processes


Plant Cell Death Processes
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Author : Larry D. Nooden
language : en
Publisher: Elsevier
Release Date : 2003-12-09

Plant Cell Death Processes written by Larry D. Nooden and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-12-09 with Science categories.


Programmed cell death is a common pattern of growth and development in both animals and plants. However, programmed cell death and related processes are not as generally recognized as central to plant growth. This is changing fast and is becoming more of a focus of intensive research. This edited work will bring under one cover recent reviews of programmed cell death, apoptosis and senescence. Summaries of the myriad aspects of cell death in plants Discussion of the broadest implications of these disparite results A unification of fields where there has been no cross talk Enables easy entry into diverse but related lines of research



Oxidative Stress And Toxicity In Reproductive Biology And Medicine


Oxidative Stress And Toxicity In Reproductive Biology And Medicine
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Author : Shubhadeep Roychoudhury
language : en
Publisher: Springer Nature
Release Date : 2022-12-06

Oxidative Stress And Toxicity In Reproductive Biology And Medicine written by Shubhadeep Roychoudhury and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-06 with Medical categories.


Volume Two advances the exploration of the fundamental principles of oxidative stress and toxicity on male (and female) reproduction. It includes the advances in research on male reproductive health, the impact of environmental factors, the protective measures using bioactive compounds and traditional medicines, and how to limit toxic exposure. It includes coverage of: Oxidative stress and male infertility Environmental stressors and sexual health Heavy metals, pesticides, fine particle toxicity and male reproduction Protective measures against oxidative stress in gametes/embryos by using bioactive compounds/phytomedicines in Assisted Reproductive Technology (ART) Role of reactive oxygen species on female reproduction Radiation and mutagenic factors affecting the male reproductive system Both volumes provide a comprehensive look at the most basic concepts and advanced research being conducted by world famous scientists and researchers in male infertility and reproduction.



Apoptosis


Apoptosis
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Author : Douglas R. Green
language : en
Publisher: Cambridge University Press
Release Date : 2011-08-22

Apoptosis written by Douglas R. Green and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-22 with Science categories.


Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.



Apoptosis Senescence And Cancer


Apoptosis Senescence And Cancer
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Author : David A. Gewirtz
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-12-17

Apoptosis Senescence And Cancer written by David A. Gewirtz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-17 with Medical categories.


Provides insight into established practices and research into apoptosis and senescence by examining techniques and research in the fields of cell death pathways, senescence growth arrest, drugs and resistance, DNA damage response, and other topics which still hold mysteries for researchers. This book concludes with established cancer therapies.



Innovative Medicine


Innovative Medicine
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Author : Kazuwa Nakao
language : en
Publisher: Springer
Release Date : 2015-10-13

Innovative Medicine written by Kazuwa Nakao and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-13 with Science categories.


This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.



Extracellular Matrix Degradation


Extracellular Matrix Degradation
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Author : William C. Parks
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-04-07

Extracellular Matrix Degradation written by William C. Parks and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-07 with Science categories.


Regulated turnover of extracellular matrix (ECM) is an important component of tissue homeostasis. In recent years, the enzymes that participate in, and control ECM turnover have been the focus of research that touches on development, tissue remodeling, inflammation and disease. This volume in the Biology of Extracellular Matrix series provides a review of the known classes of proteases that degrade ECM both outside and inside the cell. The specific EMC proteases that are discussed include cathepsins, bacterial collagenases, matrix metalloproteinases, meprins, serine proteases, and elastases. The volume also discusses the domains responsible for specific biochemical characteristics of the proteases and the physical interactions that occur when the protease interacts with substrate. The topics covered in this volume provide an important context for understanding the role that matrix-degrading proteases play in normal tissue remodeling and in diseases such as cancer and lung disease.