Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses
DOWNLOAD
FREE 30 Days
Download Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page
Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses
DOWNLOAD
FREE 30 Days
Author : Roberto De Pasquale
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-11
Cellular And Molecular Mechanisms Of Synaptic Plasticity At Hippocampal And Cortical Synapses written by Roberto De Pasquale and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-11 with Science categories.
Synaptic Plasticity
DOWNLOAD
FREE 30 Days
Author : M. Baudry
language : en
Publisher: MIT Press
Release Date : 1993
Synaptic Plasticity written by M. Baudry and has been published by MIT Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Neuroplasticity categories.
An up-to-date overview of the current status of research on the full scope of synaptic plasticity, including synaptic remodeling in response to damage, long-term depression and long-term potentiation, and learning and memory.Synaptic Plasticity presents an up-to-date overview of the current status of research on the full scope of synaptic plasticity, including synaptic remodeling in response to damage, long-term depression and long-term potentiation, and learning and memory. The contributions are written by leading experts in the field and cover approaches from biochemical, anatomical, physiological, behavioral, and computational levels. They offer hypotheses concerning the molecular and cellular mechanisms that are responsible for the various manifestations of synaptic plasticity and propose models explaining how these cellular events can be linked to the functional and behavioral expressions of these adaptive principles. ContentsIntroduction - Molecular Correlates of Activity-dependent Development and Synaptic Plasticity, S. Hockfield - Molecular Sorting in Neurons, 0. Steward - Molecular and Morphological Responses to Deafferentation in Rodents, C. E. Finch, T. H. McNeill - Forms of Long-term Potentiation Induced by NMDA and Non-NMDA Receptor Activation, T. Teyler, L. Grover - Long-term Potentiation: Biochemical Mechanisms, M. Baudry, G. Lynch - Cerebellar Mechanisms of Long-Term Depression, M. Ito - Long-term Depression: Related Mechanisms in Cerebellum, Neocortex, and Hippocampus, A. Artola, W. Singer - Theory of Synaptic Plasticity in Visual Cortex, N. Intrator, M. F. Bear, L. N. Cooper, M. A. Paradiso - A Theoretical and Experimental Strategy for Realizing a Biologically Based Model of the Hippocampus, T. W. Berger et al - Synaptic Plasticity, Learning, and Memory, S. P. Rose - Synaptic Plasticity and Memory Storage, R. F. Thompson et al
Neural Plasticity And Memory
DOWNLOAD
FREE 30 Days
Author : Federico Bermudez-Rattoni
language : en
Publisher: CRC Press
Release Date : 2007-04-17
Neural Plasticity And Memory written by Federico Bermudez-Rattoni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-17 with Psychology categories.
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Textbook Of Neural Repair And Rehabilitation
DOWNLOAD
FREE 30 Days
Author : Michael E. Selzer
language : en
Publisher: Cambridge University Press
Release Date : 2014
Textbook Of Neural Repair And Rehabilitation written by Michael E. Selzer and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Nervous system categories.
In two freestanding volumes, the Textbook of Neural Repair and Rehabilitation provides comprehensive coverage of the science and practice of neurological rehabilitation. Revised throughout, bringing the book fully up to date, this volume, Neural Repair and Plasticity, covers the basic sciences relevant to recovery of function following injury to the nervous system, reviewing anatomical and physiological plasticity in the normal central nervous system, mechanisms of neuronal death, axonal regeneration, stem cell biology, and research strategies targeted at axon regeneration and neuron replacement. New chapters have been added covering pathophysiology and plasticity in cerebral palsy, stem cell therapies for brain disorders and neurotrophin repair of spinal cord damage, along with numerous others. Edited and written by leading international authorities, it is an essential resource for neuroscientists and provides a foundation for the work of clinical rehabilitation professionals.
Plasticity Of Gabaergic Synapses
DOWNLOAD
FREE 30 Days
Author : Andrea Barberis
language : en
Publisher: Frontiers Media SA
Release Date : 2016-01-22
Plasticity Of Gabaergic Synapses written by Andrea Barberis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-22 with Electronic book categories.
Learning and memory are believed to depend on plastic changes of neuronal circuits due to activity-dependent potentiation or depression of specific synapses. During the last two decades, plasticity of brain circuits was hypothesized to mainly rely on the flexibility of glutamatergic excitatory synapses, whereas inhibitory synapses were assumed relatively invariant, to ensure stable and reliable control of the neuronal network. As a consequence, while considerable efforts were made to clarify the main mechanisms underlying plasticity at excitatory synapses, the study of the cellular/molecular mechanisms of inhibitory plasticity has received much less attention. Nevertheless, an increasing body of evidence has revealed that inhibitory synapses undergo several types of plasticity at both pre- and postsynaptic levels. Given the crucial role of inhibitory interneurons in shaping network activities, such as generation of oscillations, selection of cell assemblies and signal integration, modifications of the inhibitory synaptic strength represents an extraordinary source of versatility for the fine control of brain states. This versatility also results from the rich diversity of GABAergic neurons in several brain areas, the specific role played by each inhibitory neuron subtype within a given circuit, and the heterogeneity of the properties and modulation of GABAergic synapses formed by specific interneuron classes. The molecular mechanisms underlying the potentiation or depression of inhibitory synapses are now beginning to be unraveled. At the presynaptic level, retrograde synaptic signaling was demonstrated to modulate GABA release, whereas postsynaptic forms of plasticity involve changes in the number/gating properties of GABAA receptors and/or shifts of chloride gradients. In addition, recent research indicates that GABAergic tonic inhibition can also be plastic, adding a further level of complexity to the control of the excitatory/inhibitory balance in the brain. The present Topic will focus on plasticity of GABAergic synapses, with special emphasis on the molecular mechanisms of plasticity induction and/or expression.
Synaptic Plasticity
DOWNLOAD
FREE 30 Days
Author : Michael R. Kreutz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-02-17
Synaptic Plasticity written by Michael R. Kreutz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-02-17 with Medical categories.
This book introduces the current concepts of molecular mechanisms in synaptic plasticity and provides a comprehensive overview of cutting-edge research technology used to investigate the molecular dynamics of the synapses. It explores current concepts on activity-dependent remodeling of the synaptic cytoskeleton and presents the latest ideas on the different forms of plasticity in synapses and dendrites. Synaptic Plasticity in Health and Disease not only supplies readers with extensive knowledge on the latest developments in research, but also with important information on clinical and applied aspects. Changes in spine synapses in different brain disease states, so-called synaptopathies, are explained and described by experts in the field. By outlining basic research findings as well as physiological and pathophysiological impacts on synaptic plasticity, the book represents an essential state-of-the-art work for scientists in the fields of biochemistry, molecular biology and the neurosciences, as well as for doctors in neurology and psychiatry alike.
Cortical Plasticity
DOWNLOAD
FREE 30 Days
Author : Sam Fazeli
language : en
Publisher: Taylor & Francis
Release Date : 1996
Cortical Plasticity written by Sam Fazeli and has been published by Taylor & Francis this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Literary Criticism categories.
Understanding the mechanisms of learning and memory provides one of the major challenges of contemporary neuroscience. At the reductionist level this equates to an understanding of synaptic plasticity within cortical structures such as the hippocampus. Recently, considerable effort has been devoted to researching two forms of associative synaptic plasticity: long-term potentiation (LTP) and its counterpart, long-term depression (LTD). Increasingly, this field is being influenced by molecular biological approaches, and Cortical Plasticity brings together the recent findings on all aspects of the induction, maintenance, and expression of LTP and LTD, with an emphasis on molecular mechanisms. This book provides an invaluable overview of a rapidly expanding field and presents discussions from internationally known researchers on a number of controversial issues regarding synaptic plasticity. It will be essential reading for researchers in all areas of neuroscience.
Stress Trauma And Synaptic Plasticity
DOWNLOAD
FREE 30 Days
Author : Maxwell Bennett
language : en
Publisher: Springer
Release Date : 2019-02-01
Stress Trauma And Synaptic Plasticity written by Maxwell Bennett and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-01 with Medical categories.
This book presents the latest state of knowledge on grey matter changes in the brain following stress and trauma. Where do these changes take place and what are the underlying molecular mechanisms? These questions are addressed in several sections, providing detailed insights into the cellular and molecular alterations that occur in the brain after stress and trauma. The changes to the grey matter in certain areas of the brain are similar in stressed humans and animals, with the most likely basis for these changes being the degeneration of synaptic connections. In the book’s first sections the reader will learn about the core network of synaptic connections that are affected by stress and trauma disorders. These synaptic connections are modulated by dopamine, serotonin and Brain Derived Neurotrophic Factor (BDNF). In subsequent chapters, the NMDA-receptor mediated plasticity of these synapses is discussed, with particular attention given to how glucocorticoids can interfere with the function of BDNF and thereby affect the synapse’s physical stability. Furthermore, the reader will learn about the importance of the genetics of the glucocorticoid gene and the epigenetic control of BDNF in connection with synaptic plasticity. The authors conclude by integrating the observations summarized in the previous sections so as to present plausible hypotheses regarding the identity of the networks, synapses and molecular pathways that support fear and extinction. Providing an up-to-date overview of the mechanisms of synaptic plasticity and physiological changes in the stressed and traumatized brain, this book will appeal to researchers, clinicians and students in the neurosciences. M. R. Bennett AO is an internationally renowned neuroscientist. He is a professor of Neuroscience & University Chair at the University of Sydney, the founding director of the ‘Brain and Mind Research Institute’ and has been the president and organizer of many societies and symposia. His research has led to groundbreaking revelations in understanding synaptic functioning. He is the author of numerous papers and books, including ‘Philosophical Foundations of Neuroscience’ (2003 with Peter Hacker) and the recent works ‘Virginia Woolf and Neuropsychiatry’ (2013), ‘History of Cognitive Neuroscience (2008 with Peter Hacker) and ‘Neuroscience and Philosophy: Brain, Mind and Language (2006 with Daniel Dennett, John Searle and Peter Hacker). Prof. Bennett has received the leading award in biology and medicine in Australia (the Macfarlane Burnet Medal) as well as being made an ‘Office of the Order of Australia’ for his outstanding ‘service to the biological sciences, particularly in the field of neurosciences’. Professor J. Lagopoulos is the inaugural director of the Sunshine Coast Mind and Neuroscience – Thompson Institute, which focuses on mental health and neurological research, clinical services and teaching. He is an expert in magnetic resonance imaging (MRI) and has been involved in neuroimaging for over 20 years. His work focuses on youth mental health, post-traumatic stress disorders, traumatic brain injury and healthy brain ageing and dementia. Prof. Lagopoulos is a leading academic and medical specialist who has published more than 170 peer-reviewed papers and contributed to several books. He is member of numerous international societies, including the ‘International Society for Magnetic Resonance in Medicine’ and the ‘Organization of Human Brain Mapping’. He has received several awards, including the ‘Westmead Foundation Prize’.
The Synapse
DOWNLOAD
FREE 30 Days
Author : Virginia M. Pickel
language : en
Publisher: Elsevier
Release Date : 2013-11-16
The Synapse written by Virginia M. Pickel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-16 with Science categories.
The Synapse summarizes recent advances in cellular and molecular mechanisms of synaptic transmission and provides new insights into neuronal plasticity and the cellular basis of neurological diseases. Part 1 provides an in-depth look at structural differences and distribution of various pre- and post-synaptic proteins found at glutamatergic synapses. Part 2 is dedicated to dendritic spines and their associated perisynaptic glia, which together constitute the tripartite synapse. The spines are portrayed as major sites for calcium sequestration and local protein synthesis. Part 3 highlights the important regional and cellular differences between glutamatergic transmission and that of neurotransmitters such as dopamine and acetylcholine that are commonly found in axon terminals without synaptic membrane specializations. Part 4 provides an overview of the synapse from the time of formation to degeneration under the powerful influence of aging or hormonal decline that leads to severe deficits in cognitive function. Each chapter is illustrated with drawings and images derived from calcium imaging, electron microscopic immunolabeling, or electrophysiology. This book is a valuable reference for neuroscientists and clinical neurologists in both research and clinical settings. A comprehensive reference focused on the structure and function of the synapse Covers the links between the synapse and neural plasticity and the cellular basis of neurologic disease Detailed coverage of dendritic spines and associated perisynaptic glia—the tripartite synapse Includes in-depth coverage of synapse degeneration due to aging or hormonal decline related to severe cognitive impairment
Molecular Mechanisms Of Synaptic Plasticity
DOWNLOAD
FREE 30 Days
Author : Giuseppina Martella
language : en
Publisher: Mdpi AG
Release Date : 2023-08-28
Molecular Mechanisms Of Synaptic Plasticity written by Giuseppina Martella and has been published by Mdpi AG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-08-28 with Science categories.
The human brain has hundreds of billions of neurons, and at least 7 million dendrites have been hypothesized to exist for each neuron, with over 100 trillion neuron-neuron, neuron-muscle, and neuron-endocrine cell synapses [1,2]. Our body continually receives stimuli from the outer environment, and our brain's ability to respond to these stimuli is ensured through synaptic processes, motivating the foundations of this Special Issue. This reprint aims to underline the role of synaptic plasticity phenomena in our body and clarify the mechanism operated by neurons to guarantee these phenomena. The collection in the Issue comprises 14 papers, including 8 reviews and 6 original works, one of which is a protocol for differentiating neurons from human stem cells, and 5 are preclinical works.