Cellular And Molecular Toxicology Of Nanoparticles
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Cellular And Molecular Toxicology Of Nanoparticles
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Author : Quaiser Saquib
language : en
Publisher: Springer
Release Date : 2018-02-16
Cellular And Molecular Toxicology Of Nanoparticles written by Quaiser Saquib and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-16 with Science categories.
This edited book is a compilation of findings on the molecular and cellular toxicity of nanoparticles (NPs) in animal cell, human cells, invertebrates. The varied selection of test models will provide better understanding about the horizon of NPs toxicity. Interaction of NPs with cells and its organelles can induce toxicological consequences, including transcriptional and translational alterations, DNA damage, cytotoxicity, oxidative stress, mitochondrial dysfunction and cell death. NPs can get internalized in cells through phagocytosis, macropinocytosis, receptor-mediated endocytosis and passive penetration, which can affect varied cell types. Readers will be benefited with the compilations on basic and molecular facet of NPs toxicity. The chapters will provide a comprehensive information on the state-of-the-art methodologies. The application of toxicogenomic approaches, which is already established in nanotoxicology, has been given special consideration to unravel the toxicodynamics of nanomaterials. Among these approaches, the high-throughput RNA sequencing (RNA-Seq), which is able to build a complete map of transcriptome across different cell types and perturbations upon NPs exposure has been included. The readers are also introduced to the less studied topic on the adsorption of biomolecules (mainly proteins) on the NPs surface, constituting the so-called “biomolecular corona”. The book has been designed for scientists engaged in NPs toxicity research. Nonetheless, it should be of interest to a variety of scientific disciplines including marine biology, environmental pollution, genetics, pharmacology, medicine, drug and food material sciences, consumer products. Also, the compilations will be of interest to the environmental watchdogs, federal regulators, risk assessors and the policy makers.
Flow Cytometry Applications In Cellular And Molecular Toxicology
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Author : AB Pant
language : en
Publisher: Springer Nature
Release Date : 2025-01-22
Flow Cytometry Applications In Cellular And Molecular Toxicology written by AB Pant and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-01-22 with Medical categories.
The book explores the role of flow cytometry in varied fields, from clinical diagnosis to toxicology. This comprehensive book offers insights into biomarkers, cellular analysis, and safety evaluations. Organized into fifteen chapters, this book explores flowcytometry's historical journey, scientific validation, and implementation in toxicity studies with case studies, technical and applied approaches, pictorial representations, informative tables, and simple language, It will be an invaluable resource for researchers, academia, biopharma industries, graduate and postgraduate students, Ph.D., and post-doctoral fellows working in the fields of toxicology/biosafety, and biomedical research.
Toxicology Of Nanomaterials
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Author : Yuliang Zhao
language : en
Publisher: John Wiley & Sons
Release Date : 2016-08-29
Toxicology Of Nanomaterials written by Yuliang Zhao and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-29 with Science categories.
This book provides the reader with a comprehensive view of analytical methods for nanotoxicology studies. After an introduction to nanomaterials and toxicological studies, the book discusses various characterization methods of nanomaterials and continues with the detection of nanoparticles in vivo as well as in vitro. A variety of techniques in molecular toxicology of nanomaterials is presented, followed by a detailed explanation of interaction between nanoparticles and biomacromolecules, including the structure-toxicity relationships of nanomaterials. Finally, the book concludes with the advantages and challenges of the analytical methods for nanotoxicology.
Immunological Effects Of Nano Imaging Materials
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Author : Yang Li
language : en
Publisher: Frontiers Media SA
Release Date : 2022-04-18
Immunological Effects Of Nano Imaging Materials written by Yang Li and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-18 with Medical categories.
Biochemical Toxicology
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Author : Muharrem Ince
language : en
Publisher: BoD – Books on Demand
Release Date : 2020-07-29
Biochemical Toxicology written by Muharrem Ince and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-29 with Medical categories.
Biochemical Toxicology - Heavy Metals and Nanomaterials provides an overview of biochemical contamination, nanomaterials and toxic metals, and measurement techniques. It explains and clarifies important studies and compares and develops new and groundbreaking measurement techniques in the fields of organic and inorganic pollution and nanoscience. It is highly recommended for professionals and readers interested in the environment and human health.
Advanced Nanotechnology In Plants
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Author : Jen-Tsung Chen
language : en
Publisher: CRC Press
Release Date : 2024-02-22
Advanced Nanotechnology In Plants written by Jen-Tsung Chen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-02-22 with Science categories.
Nanotechnology uses nanomaterials/nanoparticles that can penetrate plant cells and interact with intracellular organelles and metabolites impacting plant growth, development, physiology, and biochemistry. Advanced Nanotechnology in Plants: Methods and Applications explores emerging plant nanotechnology, covering advanced methods and applications with an emphasis on the mitigation of plant diseases and environmental stressors. This technology can lead to the improvement of crop quality and yield to face the challenge of global climate change with an expanding global population. Features: Summarizes advanced methods and current applications of nanotechnology to mitigate plant stress Supports the Paris Agreement, which tackles three main objectives for sustainably increasing agricultural productivity and incomes, adapting and building resilience to climate change, and reducing and/or removing greenhouse gas emissions Discusses potential uses and future directions in green nanotechnology for smart and sustainable agriculture The content fits the goals of the UN SDGs contributing to goals 12 and 15 for responsible consumption and production and sustainable use of terrestrial ecosystems Provides current research findings of engineered nanoparticles for phytoremediation This book is a reference for students, researchers, and scientists in the field of plant sciences and nanotechnology. It is also useful for those in green chemistry, and environmental sciences, and can be a practical handbook for academics, including teachers, students, and agricultural experts.
Pathophysiology Of Cancer An Interdisciplinary Approach
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date : 2025-08-25
Pathophysiology Of Cancer An Interdisciplinary Approach written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-08-25 with Medical categories.
The “Pathophysiology of Cancer: An Interdisciplinary Approach” is the twenty-two volume of the “Interdisciplinary Cancer Research” series and a comprehensive volume on the pathophysiology of cancer. The volume starts with a few chapters on the risk of cancer development and carcinogenesis, including mitochondrial energy metabolism in carcinogenesis and the role of mitochondrial DNA mutations in cancer development. The obesity epidemic and cancer risk, urban road dust, genotoxicity, aberrant glycosylation, melatonin, and matrix metalloproteinases as players in cancer development and progression are explained in other chapters. The subsequent chapters discuss vascular endothelium, extracellular vesicles and extracellular matrix, circulating tumor cells, cancer-associated programmed-cell death, and epithelial-to-mesenchymal transition in cancer. Importance of antioxidants, decoding metabolic changes and effects of secondary metabolites in cancer therapy are the subjects of the concluding chapters. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for those who wish to have an update on the pathophysiology of cancer.
Applications Of Nanomaterials In Human Health
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Author : Firdos Alam Khan
language : en
Publisher: Springer Nature
Release Date : 2020-06-20
Applications Of Nanomaterials In Human Health written by Firdos Alam Khan and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-20 with Technology & Engineering categories.
This book reviews the various applications of nanotechnology in human health. The introductory chapters focus on the classifications, types, synthesis, and characterization of various types of nanomaterials, while subsequent chapters highlight current applications of nanomaterials in the diagnosis and treatment of microbial and viral infections, and also in stem cell biology and regenerative medicine. Further, the book explores the potential role of nanomaterials in connection with neuronal differentiation, neuronal protection, and neurological diseases. It demonstrates the use of nanotechnology to diagnose and treat genetic disorders, as well as endocrine and metabolic syndrome diseases. It also discusses the ethics and the negative impacts of nanomaterials on human health. Lastly, it examines the intellectual property aspects and government regulations associated with the research, design, and commercialization of nanotechnology-based products. Given its scope, it offers a valuable resource for all researchers and professionals working with nanotechnology-based applications in human health.
Handbook Of Materials For Nanomedicine
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Author : Vladimir Torchilin
language : en
Publisher: CRC Press
Release Date : 2020-03-16
Handbook Of Materials For Nanomedicine written by Vladimir Torchilin and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-16 with Science categories.
In the fast-developing field of nanomedicine, a broad variety of materials have been used for the development of advanced delivery systems for drugs, genes, and diagnostic agents. With the recent breakthroughs in the field, we are witnessing a new age of disease management, which is governed by precise regulation of dosage and delivery. This book presents the advances in the use of metal-based and other nanomaterials for medical imaging, diagnosis, theranostics, and drug delivery. It discusses silver, hybrid gold, and surface-modified magnetic nanoparticles, fluorescent quantum dots, lipid bubbles, and nanobubbles. It provides all available information about these materials and describes in detail their advantages and disadvantages and the areas where they could be utilized successfully. The text also covers topics such as improving bioactivity of poorly soluble actives, cellular and molecular toxicology of nanoparticles, and biofate of nanoemulsions.
Handbook Of Oxidative Stress In Cancer Therapeutic Aspects
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Author : Sajal Chakraborti
language : en
Publisher: Springer Nature
Release Date : 2022-09-28
Handbook Of Oxidative Stress In Cancer Therapeutic Aspects written by Sajal Chakraborti and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-09-28 with Medical categories.
This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy.