Cellular Biological Approaches To Treating Peripheral Nerve Injuries
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Cellular Biological Approaches To Treating Peripheral Nerve Injuries
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Author : A. W. English
language : en
Publisher:
Release Date : 2015
Cellular Biological Approaches To Treating Peripheral Nerve Injuries written by A. W. English and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with categories.
Peripheral Nerve Regeneration
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Author : Giovanna Gambarotta
language : en
Publisher: Frontiers Media SA
Release Date : 2019-12-24
Peripheral Nerve Regeneration written by Giovanna Gambarotta and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-24 with categories.
Cell Engineering And Regeneration
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Author : Heinz Redl
language : en
Publisher: Springer
Release Date : 2017-02-16
Cell Engineering And Regeneration written by Heinz Redl and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-16 with Technology & Engineering categories.
This reference work presents the origins of cells for tissue engineering and regeneration, including primary cells, tissue-specific stem cells, pluripotent stem cells and trans-differentiated or reprogrammed cells. There is particular emphasis on current understanding of tissue regeneration based on embryology and evolution studies, including mechanisms of amphibian regeneration. The book covers the use of autologous versus allogeneic cell sources, as well as various procedures used for cell isolation and cell pre-conditioning , such as cell sorting, biochemical and biophysical pre-conditioning, transfection and aggregation. It also presents cell modulation using growth factors, molecular factors, epigenetic approaches, changes in biophysical environment, cellular co-culture and other elements of the cellular microenvironment. The pathways of cell delivery are discussed with respect to specific clinical situations, including delivery of ex vivo manipulated cells via local and systemic routes, as well as activation and migration of endogenous reservoirs of reparative cells. The volume concludes with an in-depth discussion of the tracking of cells in vivo and their various regenerative activities inside the body, including differentiation, new tissue formation and actions on other cells by direct cell-to-cell communication and by secretion of biomolecules.
Neuropathic Pain
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Author : Jianguo Cheng
language : en
Publisher: Oxford University Press
Release Date : 2019-01-21
Neuropathic Pain written by Jianguo Cheng and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-01-21 with Medical categories.
Neuropathic pain is one of the most common, most debilitating, most costly, and most difficult to treat categories of chronic pain conditions that are characterized by a lesion or disease of the somatosensory nervous system. Managing neuropathic pain is challenging and requires skillful assessment and comprehensive and integrated treatment strategies that are mechanism-guided, evidence-based, and individualized. However, these critical and integral elements are very fragmented in the current literature. The mechanistic understanding of neuropathic pain is typically found in basic research articles. Clinical research evidence is presented in forms of clinical trials with emphasis on minimizing biases such as those from patient selection and assessment. Individualized considerations for each patient are usually presented in case reports and problem-based learning discussions. This book overcomes these barriers and integrates all the critical elements around individual patient care into a coherent management strategy that is practical and applicable to daily clinical practice. Rather than compiling what have been published in the literature, this work emphasizes on identifying and highlighting the key points or findings that guide decision-making in clinical practice. It integrates the key points around a typical case scenario that not only represents the core of the diagnostic and therapeutic processes but also allows introduction and differentiation of painful conditions that bare similarities with the case in hand. The overarching goal is to improve clinical outcomes through better understanding of the mechanisms, more accurate diagnosis, and wiser and more comprehensive treatment strategies.
Peripheral Nerve Disorders And Treatment
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Author : Hande Turker
language : en
Publisher:
Release Date : 2020
Peripheral Nerve Disorders And Treatment written by Hande Turker and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with categories.
Neuropathies are one of the main neurological problems in everyday life, and they still have many partially understood parts and unknowns both for physicians and patients. Many systemic conditions may exist within them and therefore they may be difficult to treat. In this book we provide current knowledge concerning neuropathies, which we believe you will find interesting. The subject ''neuropathies'' comprises a number of topics, and each and every one could be the subject of a textbook. On the other hand, this book was never designed as one. This book should be read without prejudgment because the content may not be compatible with general but repeated assumptions and guidelines. However, I believe that the book may be an inspiration for many young investigators as well. It contains current approaches and knowledge and we sincerely believe and hope that it will answer your queries regarding new perspectives about neuropathy in general.
Surgical Disorders Of The Peripheral Nerves
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Author : Rolfe Birch
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-01-21
Surgical Disorders Of The Peripheral Nerves written by Rolfe Birch and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-21 with Medical categories.
Since the highly praised first edition of Surgical Disorders of the Peripheral Nerves was published in 1998, greater understanding of the the molecular and cellular events which underlie the response of nerves to injury, regeneration and neuropathic pain has been achieved. This second edition has been fully updated in line with new clinical knowledge, and also incorporates the extensive study of thousands of surgical case studies spanning repairs of the supraclavicular plexus in the adult, the birth lesion of the brachial plexus,compound nerve injury and iatrogenous injury. Beginning with the fundamentals of the anatomy and function of the peripheral nervous system, and working its way through various types of injury, operative methods, the regeneration and recovery of nerves, surgical reconstruction, pain, and rehabilitation, this eloquently written work provides the reader with the solid understanding required to successfully perform surgery on the peripheral nervous system. Dr Shelagh Smith, joined by Dr Ravi Knight, has rewritten the chapter Electrodiagnosis. Professor Tara Renton has written a new chapter on injuries to the trigeminal nerve in maxilla-facial and dental work. The drawings, by Mr Philip Wilson, are new. Most of the 700 illustrations are also new. This thorough and authoritative look at the surgical treatment of the peripheral nerves is fully illustrated throughout with exquisite line diagrams and clear, instructive photographs.
Neural Crest Stem Cells
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Author : Maya Sieber-Blum
language : en
Publisher: World Scientific
Release Date : 2012
Neural Crest Stem Cells written by Maya Sieber-Blum and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
Offers readers an understanding of the development of neural crest cells, which is crucial as many birth defects and tumours are of neural crest origin. Delving into stem cells from different locations of the body, this book explores the best possible source of such cells for the use in medical applications.
Musculoskeletal Disorders And The Workplace
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2001-06-24
Musculoskeletal Disorders And The Workplace written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-06-24 with Business & Economics categories.
Every year workers' low-back, hand, and arm problems lead to time away from jobs and reduce the nation's economic productivity. The connection of these problems to workplace activities-from carrying boxes to lifting patients to pounding computer keyboards-is the subject of major disagreements among workers, employers, advocacy groups, and researchers. Musculoskeletal Disorders and the Workplace examines the scientific basis for connecting musculoskeletal disorders with the workplace, considering people, job tasks, and work environments. A multidisciplinary panel draws conclusions about the likelihood of causal links and the effectiveness of various intervention strategies. The panel also offers recommendations for what actions can be considered on the basis of current information and for closing information gaps. This book presents the latest information on the prevalence, incidence, and costs of musculoskeletal disorders and identifies factors that influence injury reporting. It reviews the broad scope of evidence: epidemiological studies of physical and psychosocial variables, basic biology, biomechanics, and physical and behavioral responses to stress. Given the magnitude of the problem-approximately 1 million people miss some work each year-and the current trends in workplace practices, this volume will be a must for advocates for workplace health, policy makers, employers, employees, medical professionals, engineers, lawyers, and labor officials.
Complications In Neuroanesthesia
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Author : Hemanshu Prabhakar
language : en
Publisher: Academic Press
Release Date : 2016-02-11
Complications In Neuroanesthesia written by Hemanshu Prabhakar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-02-11 with Medical categories.
Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients. Quick and easy reference for understanding problems in neuroanesthesia Provides comprehensive insights into all possible complications occurring during perioperative management of neurosurgical and neurologic patients Includes useful section with clinical case studies of complications in neuroanesthesia
Peripheral Nerve Regeneration
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Author : Ana Colette Maurício
language : en
Publisher: BoD – Books on Demand
Release Date : 2017-05-31
Peripheral Nerve Regeneration written by Ana Colette Maurício and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-05-31 with Science categories.
Peripheral nerve injuries are a high-incidence clinical problem that greatly affects patients' quality of life. Despite continuous refinement of microsurgery techniques, peripheral nerve repair still stands as one of the most challenging tasks in neurosurgery, as functional neuromuscular recovery is rarely satisfactory in these patients. Therefore, the improvement of surgical techniques and the clinical application of innovative therapies have been intensively studied worldwide. Direct nerve repair with epineural end-to-end sutures is still the gold standard treatment for severe neurotmesis injuries but only in cases where well-vascularized tension-free coaptation can be achieved. When peripheral nerve injury originates a significant gap between the nerve stumps, nerve grafts are required, with several associated disadvantages. Therefore, the development of scaffolds by tissue engineering can provide efficient treatment alternatives to stimulate optimum clinical outcome. Nerve conduit tailoring involves reaching ideal wall pores, using electrospinning techniques in their fabrication, surface coating with extracellular matrix materials, and adding of growth factors or cell-based therapies, among other possibilities. Also, intraluminal cues are employed such as the filling with hydrogels, inner surface modification, topographical design, and the introduction of neurotrophic factors, antibiotics, anti-inflammatories and other pharmacological agents. A comprehensive state of the art of surgical techniques, tissue-engineered nerve graft scaffolds, and their application in nerve regeneration, the advances in peripheral nerve repair and future perspectives will be discussed, including surgeons' and researchers' own large experience in this field of knowledge.