Cellular Peptidases In Immune Functions And Diseases

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Cellular Peptidases In Immune Functions And Diseases

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Author : Siegfried Ansorge
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Cellular Peptidases In Immune Functions And Diseases written by Siegfried Ansorge and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.

Proceedings of an international conference held in Magdeburg, Germany, November 3-5, 1996

Cellular Peptidases In Immune Functions And Diseases 2

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Author : Jürgen Langner
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

Cellular Peptidases In Immune Functions And Diseases 2 written by Jürgen Langner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.

Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.

Cellular Peptidases In Immune Functions And Diseases 2

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Author : Jürgen Langner
language : en
Publisher: Springer
Release Date : 2000-05-31

Cellular Peptidases In Immune Functions And Diseases 2 written by Jürgen Langner and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-05-31 with Medical categories.

Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.

Ectopeptidases

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Author : Jürgen Langner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Ectopeptidases written by Jürgen Langner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.

The idea to compile recent results on the ectoenzymes aminopeptidase N/CD13 and dipeptidylpeptidase IV/CD26 arose from the great interest given by readers world-wide to the two proceedings volumes edited by us in 1997 and 2000 (Ansorge and Langner, 1997; Langner and Ansorge, 2000). These volumes contained the presentations at two symposia held in Magdeburg (Germany) in 1996 and 1999 under the title "Cellular peptidases in immune functions and diseases", which was also the name of the Sonderforschungsbereich in Magdeburg, sponsored by the Deutsche Forschungsgemeinschaft between 1995 and 2001. Our groups in Magdeburg and Halle during the last two decades have provided results on these two enzymes in cells of the hematopoietic system that justify a review in an edited monograph like the present one (see the reviews by Kahne et at. , 1999; Lendeckel et at. ,1999; Riemann et at. , 1999). There are, however, many other groups in Europe, US and Japan which made important contributions to this field and particularly in topics improving the understanding of physiological and pathophysiological roles ofAPN/CD13 and DPIV/CD26. Therefore we decided to invite some of them to contribute reviews of their results to this book. Having worked for about 40 years in the field of proteolysis, for both of us to see the development of activities and knowledge from protein chemistry and enzymology to physiology and pathophysiology and even to therapy is very stimulating and fascinating. Of course, this development also reflects the dramatic improvement and refinement of methods.

Dipeptidyl Aminopeptidases In Health And Disease

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Author : Martin Hildebrandt
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-04-11

Dipeptidyl Aminopeptidases In Health And Disease written by Martin Hildebrandt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-04-11 with Medical categories.

Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: - Structure and function of dipeptidyl aminopeptidases, - DPP IV-like proteins, - Immune mechanisms and immune disorders, - Cancer and angiogenesis, - Diabetes and metabolism, - Therapeutic implications.

Aminopeptidases In Biology And Disease

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Author : Nigel M. Hooper
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Aminopeptidases In Biology And Disease written by Nigel M. Hooper and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

Aminopeptidases in Biology and Disease provides a comprehensive review of the emerging role of aminopeptidases in a range of biological processes and disease situations. Processes as diverse as angiogenesis, antigen presentation, neuropeptide and hormone processing, pregnancy and reproduction, protein turnover, memory, inflammation, tumour growth, cancer and metastasis, blood pressure and hypertension all critically involve one or more aminopeptidases. The individual chapters have been written by experts in the field who have provided detailed accounts of the central roles played by various aminopeptidases in biology and disease.

Index Medicus

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Author :
language : en
Publisher:
Release Date : 2001

Index Medicus written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Medicine categories.

Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Biomedical Index To Phs Supported Research

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Author :
language : en
Publisher:
Release Date : 1988

Biomedical Index To Phs Supported Research written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988 with Medicine categories.

Surgical Research In Implant Dentistry

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Author : Michel M. Dard
language : en
Publisher: Springer Nature
Release Date : 2023-11-25

Surgical Research In Implant Dentistry written by Michel M. Dard and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-25 with Medical categories.

This book explores, in a comprehensive and systematic manner, Surgical Research methodologies to the design and development of investigational studies in the field of implant-based oral rehabilitation. Such studies are linked in a chain binding in vitro, in vivo, ex vivo, and digital evaluations. An ambitious objective consists in exposing how investigators can generate and deliver knowledge by capturing synergy coming from preclinical and clinical trials. Accordingly, throughout the book, translational aspects are closely scrutinized. The opening chapters consider materials, methods and procedures for preclinical and clinical studies in which approaches and models are extensively described. The focus then moves to the process by which application of histology, biomechanics, biomarkers, cellular/molecular biology, and imaging technologies lead to new results and consequently novel treatment concepts in implant dentistry, implant borne prosthetic rehabilitations and the replacement or regeneration of tissues. Finally, the exciting opportunities afforded by the digital world are addressed. This book shall be a valuable resource and time-saving tool for a wide audience of researchers, students, practitioners, and academics.

Biomedical Index To Phs Supported Research Pt A Subject Access A H

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Author :
language : en
Publisher:
Release Date : 1992

Biomedical Index To Phs Supported Research Pt A Subject Access A H written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Medicine categories.