Central Neurotransmitter Turnover
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Central Neurotransmitter Turnover
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Author : C. J. Pycock
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Central Neurotransmitter Turnover written by C. J. Pycock and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
The concept of chemical transmission in the central nervous system has taken some time to be generally accepted, but an increasing number of compounds are now being recognized as hav ing a transmitter role in the brain. The acetylcholine system was the first to be discovered in the periphery and its charac teristic features of storage of transmitter in vesicles in the nerve terminal, its electrically-evoked release and rapid extra neuronal breakdown were considered to be necessary criteria for any neurotransmitter candidate. The subsequent elucidation of the noradrenergic system made it apparent that rapid enzymatic breakdown was not essential for a released transmitter, and the possibility of high-affinity re-uptake processes became establ ished as an alternative means of terminating the synaptic actions of a transmitter. With the eventual acceptance of the amino acids as excitat ory or inhibitory transmitters, the requirement for a transmit ter to be present in a low concentration overall (although locally concentrated in specific terminals) also had to be discarded. This necessitated the additional concept of specif ic metabolic pools with different functions being located in different cells or within different regions of the same cell. Some localization of glutamate and aspartate remote from excit able membranes is clearly essential since their overall brain concentrations would be sufficient to maximally depolarize the majority of neurones in the brain. The concept of separate metabolic pools has been supported by stUdies on turnover rate (see Chapter 5).
Central Neurotransmitter Turnover
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Author : Christopher J. Pycock
language : en
Publisher: University Park Press
Release Date : 1981-01-01
Central Neurotransmitter Turnover written by Christopher J. Pycock and has been published by University Park Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981-01-01 with Neurotransmitters categories.
Choline And Acetylcholine Handbook Of Chemical Assay Methods
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Author : Israel Hanin
language : en
Publisher:
Release Date : 1974
Choline And Acetylcholine Handbook Of Chemical Assay Methods written by Israel Hanin and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1974 with Science categories.
Neural Plasticity And Memory
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Author : Federico Bermudez-Rattoni
language : en
Publisher: CRC Press
Release Date : 2007-04-17
Neural Plasticity And Memory written by Federico Bermudez-Rattoni and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-04-17 with Psychology categories.
A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniq
Neurotransmitters And Anterior Pituitary Function
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Author : Giuseppe Nistico
language : en
Publisher: Elsevier
Release Date : 2012-12-02
Neurotransmitters And Anterior Pituitary Function written by Giuseppe Nistico and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
Neurotransmitters and Anterior Pituitary Function discusses research findings on neurotransmitter-neurohormone interactions in the control of the anterior pituitary. This book contains five chapters that specifically tackle the most salient constituents of the neural-endocrine communication system in mammals. This book deals first with the biochemistry, physiology, and pharmacology of proved or putative neurotransmitters, as well as some of the techniques used for determining their synthesis or turnover in the central nervous system (CNS) of experimental animals or in man. These topics are followed by a discussion on the principal functions of the most well-known neurotransmitter containing neurons based on sophisticated techniques for neurotransmitter measurements. A chapter highlights both traditional and a vast series of developed drugs that affect both neurotransmitter and neuroendocrine function. Discussions then shift to the experimental evidence on pituitary function control by the brain through releasing and inhibiting hormones secreted by hypothalamic neuroendocrine cells; the chemical isolation, identification, and synthesis of hypothalamic neurohormones; and concepts of their mechanism of action at the level of the pituitary cells. This text further explores the role of specific brain neurotransmitters in controlling pituitary hormone secretions in both experimental animals and in man and the possible CNS site(s) where neurotransmitters and neurohormones interact for the control of anterior pituitary secretion. The concluding chapter describes the actual or potential application of neuropharmacologic approaches to the diagnosis of and therapy for specific disorders of neuroendocrine function. Clinical neuroendocrinologists and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.
Food Components To Enhance Performance
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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 1994-02-01
Food Components To Enhance Performance written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-02-01 with Medical categories.
The physiological or psychological stresses that employees bring to their workplace affect not only their own performance but that of their co-workers and others. These stresses are often compounded by those of the job itself. Medical personnel, firefighters, police, and military personnel in combat settingsâ€"among othersâ€"experience highly unpredictable timing and types of stressors. This book reviews and comments on the performance-enhancing potential of specific food components. It reflects the views of military and non-military scientists from such fields as neuroscience, nutrition, physiology, various medical specialties, and performance psychology on the most up-to-date research available on physical and mental performance enhancement in stressful conditions. Although placed within the context of military tasks, the volume will have wide-reaching implications for individuals in any job setting.
Current Catalog
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Author : National Library of Medicine (U.S.)
language : en
Publisher:
Release Date :
Current Catalog written by National Library of Medicine (U.S.) and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on with Medicine categories.
First multi-year cumulation covers six years: 1965-70.
Neurotransmitters And Drugs
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Author : Zygmunt L. Kruk
language : en
Publisher: Springer
Release Date : 2014-11-14
Neurotransmitters And Drugs written by Zygmunt L. Kruk and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-14 with Science categories.
Biochemistry Of Characterised Neurons
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Author : Neville N. Osborne
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Biochemistry Of Characterised Neurons written by Neville N. Osborne and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Biochemistry of Characterised Neurons provides a report on the progress made in the analysis of the biology of specific neurons in the central nervous system. This book emphasizes the biochemical, morphological, and functional aspects of characterized neurons, including ways and sophisticated techniques of isolating them. This publication is divided into 11 chapters. The first chapter evaluates the relevance of working with single neurons. Chapters 2 to 6 discuss specific, characterized, invertebrate neurons containing one of the putative neurotransmitter substances. Chapter 7 deals with the biochemistry of a unique vertebrate (Torpedo) cholinergic system that enables pure cholinergic neuronal cell bodies and endings to be analyzed separately. The sensitive radiochemical procedures used to analyze transmitter substances and transmitter enzymes, and how they can be adapted to map the distribution of transmitters in individual neurons of Aplysia, are discussed in Chapter 8. Chapter 9 describes methods for the analysis of specific cells in the retina, while Chapters 10 and 11 focus on the analysis of proteins within defined neurons. This text is beneficial to biochemists and students interested in analyzing neurons.
In Vivo Perfusion And Release Of Neroactive Substances
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Author : Alejandro Bayon
language : en
Publisher: Elsevier
Release Date : 2012-12-02
In Vivo Perfusion And Release Of Neroactive Substances written by Alejandro Bayon and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.
In Vivo Perfusion and Release of Neuroactive Substances: Methods and Strategies examines the perfusion and release methods and strategies used to study in vivo neurochemistry in relation to electrophysiological and behavioral events. More specifically, it reviews methodological alternatives and experimental strategies for investigating the in vivo perfusion and release of brain substances in the central nervous system. It also assesses the potential and limitations of in vivo perfusion methods, including high-pressure liquid chromatography and highly sensitive as well as specific immunoassays and receptor assays, as a means to discover novel neurochemicals recovered from perfusates. Organized into two sections comprised of 17 chapters, this book begins with an overview of methodological alternatives and experimental strategies that are deemed critical for the outcome of research on the perfusion and release of neuroactive substances in the CNS. It then discusses the personal experiences of the scientists in studying the in vivo neurochemistry and its correlation with other neural events. The chapters that follow focus on the chemical, bioelectrical, and behavioral aspects of brain function; interdisciplinary techniques for approaching problems of neuronal connectivity, neuroendocrinology, motor behavior, neuropathology, etc.; technical issues associated with push-pull perfusion in unanesthetized and unrestrained experimental animals; hippocampal involvement in the effects of ethyl alcohol; and the use of the push-pull perfusion technique in neuroendocrinology. This book will be of interest to specialists and neuroscientists as well as students working in the fields of neuroscience, neurochemistry, and neuroendocrinology.