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Cerebrospinal Fluid Diagnostics In Neurology


Cerebrospinal Fluid Diagnostics In Neurology
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Cerebrospinal Fluid In Clinical Neurology


Cerebrospinal Fluid In Clinical Neurology
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Author : Florian Deisenhammer
language : en
Publisher: Springer
Release Date : 2015-02-05

Cerebrospinal Fluid In Clinical Neurology written by Florian Deisenhammer and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-02-05 with Medical categories.


The cerebrospinal fluid (CSF) is an invaluable diagnostic tool in clinical neurology, not only in the evaluation of inflammatory, degenerative, and malignant diseases of the nervous system, but also in the diagnosis of all forms of cerebral and subarachnoidal bleedings. The CSF can be easily obtained by lumbar puncture and a set of basic analyses can be conducted using relatively simple laboratory methods. By combining different CSF parameters, a wide range of diagnostic entities can be identified. However, properly interpreting the test results requires a high level of expertise and cannot be achieved by just reporting on individual analytic values. This book covers essential aspects of cerebrospinal fluid analysis and its use in the diagnosis of common neurological diseases. The first part addresses preclinical aspects such as the history of CSF, as well as the anatomical, physiological, and biological background of this valuable fluid. In addition, CSF collection, its preanalytical and methodological implications, and the increasing number of disease-specific markers in CSF are discussed in detail. Lastly, CSF analyses are put into context with clinical syndromes, demonstrating their diagnostic value in neurological clinical practice. Cerebrospinal Fluid in Clinical Neurology helps readers understand the preanalytical and analytical aspects of CSF diagnostics and offers a valuable reference guide for interpreting CSF results during the clinical work-up for neurological patients.



Cerebrospinal Fluid Diagnostics In Neurology


Cerebrospinal Fluid Diagnostics In Neurology
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Author : Hansotto Reiber
language : en
Publisher: Springer Nature
Release Date :

Cerebrospinal Fluid Diagnostics In Neurology written by Hansotto Reiber and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.




Laboratory Diagnosis In Neurology


Laboratory Diagnosis In Neurology
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Author : Brigitte Wildemann
language : en
Publisher: Thieme
Release Date : 2011-01-01

Laboratory Diagnosis In Neurology written by Brigitte Wildemann and has been published by Thieme this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-01 with Medical categories.


Up-to-date, comprehensive, and beautifully illustrated, Laboratory Diagnosis in Neurology presents all the measuring parameters and methods relevant to the analysis of cerebrospinal fluid, serum, and tissues affected by neurologic disease and syndromes. Following an introduction to basic concepts, the book guides clinicians through the methods of CSF analysis, neurochemical examinations, clinical applications of neuroimmunology, microbiology and virology, neurogenetic tests, and evaluation of biopsies. Readers will learn about the equipment and various procedures, and how to effectively differentiate similar methods. In the final section of the book, the authors provide a systematic introduction to the pathophysiology and laboratory findings for specific clinical disorders, indications for particular test methods, and criteria for diagnostic interpretation.Key features: Clear presentation of pearls, pitfalls, and practical tips in blue boxes for at-a-glance review Contributions by neurologists, psychiatrists with experience in laboratory analysis, clinical chemists, and neurochemists More than 140 high-quality illustrations, mostly in full color, demonstrating common findings Appendix with basic rules for interpreting disease-specific patterns, recommendations for quality control, and a list of the most important reference values An indispensable tool for neurologists, laboratory physicians, and pathologists, this book is also a valuable reference for neurosurgeons, internists, and psychiatrists.



Cerebrospinal Fluid In Neurologic Disorders


Cerebrospinal Fluid In Neurologic Disorders
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Author :
language : en
Publisher: Elsevier
Release Date : 2017-11-17

Cerebrospinal Fluid In Neurologic Disorders written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-17 with Medical categories.


Cerebrospinal Fluid in Neurologic Disorders, Volume 146 provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker. The second part addresses the main purpose of the volume, describing CSF from a research perspective in context with the most important diagnostic entities in neurology. The book's authors provide insight into the current understanding of CSF changes in these various conditions and what it tells us about the nature of neurological diseases. Furthermore, methodological aspects are discussed, as are shortcomings that need to be addressed. Finally, the book provides an outlook for potential directions that can be explored to improve the various aspects of CSF research with the ultimate goal of being incorporated in clinical practice. Provides a brief overview on the current use of CSF in clinical routine, the physiology of CSF, and its usefulness and potential as a biomarker Addresses relevant research in context with the most important diagnostic entities in neurology Edited by leading authors in CSF research from around the globe, presenting the broadest, most expert coverage available



Cerebrospinal Fluid


Cerebrospinal Fluid
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Author : Lawrence E. Keen
language : en
Publisher: Nova Science Publishers
Release Date : 2014

Cerebrospinal Fluid written by Lawrence E. Keen and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014 with Biochemical markers categories.


The cerebrospinal fluid (CSF) is a dynamic, metabolically active fluid that occupies the subarachnoid space and the ventricular system around the brain, and has many important functions. CSF is a promising body fluid for the search of biomarkers associated with neurological disease, because the CSF has more physical contact with brain than any other fluids, biochemical changes related to many pathology may be reflected in the CSF. Although CSF is obtained by lumbar puncture, invasive and potentially painful for the patient, it is probably the most informative fluid in biomarkers discovery for neurological disease prognosis. This book discusses CSF biomarkers; novel developed biomarkers in neurological diseases; CSF biochemical markers of cerebral metabolism in dogs; and guidance for the selection and interpretation of laboratory tests.



Diagnostic Tests In Neurology


Diagnostic Tests In Neurology
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Author : G. David Perkin
language : en
Publisher: Springer
Release Date : 2013-12-11

Diagnostic Tests In Neurology written by G. David Perkin and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-11 with Medical categories.


In writing this book, I have attempted to provide information about the relative value of particular investigations in various neurological disorders. The book is divided into sections dealing with the methods of investigation, the investigation of particular symptoms, the investigation of specific neurological conditions and neurological emergencies. Finally, the assessment of certain disorders suggesting a particular anatomical localization, for example isolated optic atro phy, is considered. Following an appraisal of the literature, each section ends with a recommendation regarding appropriate investigation. In some in stances this is supported by an algorithm. Specific recommendations have been attempted despite the risk of producing over-dogmatic criteria for patient management. A small amount of illustrative material is included. I am grateful to colleagues at Charing Cross Hospital who have provided some of the illustrations. Figs 1. 4, 2. 1 and 10. 2 are reproduced from Atlas of Clinical Neurology, by G. D. Perkin eta/. , Gower Medical Publishing, 1986, courtesy of the publishers. Fig. 3, in Chapter 4, is reproduced from Brain, vol. 2 104, 753-78, 1981, courtesy of the editor and Dr. R. S. J. Frackowiak. Fig. 6, in the same chapter, is reproduced from Fig. 62 in the Atlas of Positron Emission Tomography, edited by E-D. Heiss et al. , Springer-Verlag, 1985, courtesy of the publishers and Dr. J. C. Maziotta. Fig. 3 in Chapter 6 is reproduced from Fig.



Cerebrospinal Fluid In Neurology And Psychiatry


Cerebrospinal Fluid In Neurology And Psychiatry
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Author : Joseph R. Bianchine
language : en
Publisher: Springer
Release Date : 2013-11-11

Cerebrospinal Fluid In Neurology And Psychiatry written by Joseph R. Bianchine and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.


Scientists have speculated as to the nature of cerebrospinal fluid (CSF) - "the third circulation" or "vital spirit" for centuries. Just what is this mysterious bathing solution of the central nervous system? Is it a vehicle of transport for an "animal spirit" directing all our activities, as thought by Galen (Singer, 1956) or but a "modified tap water" (Halliburton, 1917)? With the advent of lumbar puncture, cerebrospinal fluid has become a readily available and important means of studying disease affecting the nervous system. In recent years, many sophisticated tools including com puter guided gas chromatography/mass spectrometry and high performance liquid chromatography have made it possible to identify and quantify many constituents of this fluid. The CSF has an enormous, though largely "untapped", potential in aiding diagnosis and evaluating treatment of many neurological, psychiatric and systemic disorders. As the ependyma is only a diffusional barrier between the CSF and extracellular fluid of the brain for many compounds, changes in the concentration of these compounds in the CSF may reflect disease processes in the brain.



Proteins Of The Cerebrospinal Fluid


Proteins Of The Cerebrospinal Fluid
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Author : Edward J. Thompson
language : en
Publisher: Elsevier
Release Date : 2005-07-14

Proteins Of The Cerebrospinal Fluid written by Edward J. Thompson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-07-14 with Science categories.


The analysis of the protein content of the Cerebrospinal Fluid (CSF) is a central tool in the diagnosis of a number of diseases, including Multiple Sclerosis and Encephalitis. Proteins of the Cerebrospinal Fluid is a complete revision of the first edition published 16 years ago and reflects the advances in the field in that period. Containing the most comprehensive reference list available today with over 1300 references cross-indexed according to topics, it also includes many classical works that cannot be easily found through the public literature database (like PubMed). This book covers new areas of research such as the use of the analysis of protein content in the CSF to guide the prognosis of patients with severe head injury and/or stroke (currently being tested using technology which can be applied at the bedside to yield results within 15 minutes). With many new or completely revised illustrations, this book serves as not only a reference on the topic, but also a lab manual for bench work with recipes, and a clinical reference on individual diseases. Introduces the Eastern blotting, the technique considered the "gold standard" by the US Food & Drug Administration (FDA) for the demonstration of IgG by immunofixation following isoelectric focusing Provides numerous tables for ease-of-use Extensively cross-referenced with over 1300 references



Cerebrospinal Fluid


Cerebrospinal Fluid
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Author : Lawrence E. Keen
language : en
Publisher:
Release Date : 2014-05-22

Cerebrospinal Fluid written by Lawrence E. Keen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-22 with Cerebrospinal fluid categories.


The cerebrospinal fluid (CSF) is a dynamic, metabolically active fluid that occupies the subarachnoid space and the ventricular system around the brain, and has many important functions. CSF is a promising body fluid for the search of biomarkers associated with neurological disease, because the CSF has more physical contact with brain than any other fluids, biochemical changes related to many pathology may be reflected in the CSF. Although CSF is obtained by lumbar puncture, invasive and potentially painful for the patient, it is probably the most informative fluid in biomarkers discovery for neurological disease prognosis. This book discusses CSF biomarkers; novel developed biomarkers in neurological diseases; CSF biochemical markers of cerebral metabolism in dogs; and guidance for the selection and interpretation of laboratory tests.



The Cerebrospinal Fluid


The Cerebrospinal Fluid
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Author : Robert M. Herndon
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

The Cerebrospinal Fluid written by Robert M. Herndon and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


For centuries the great minds of medical science puzzled over the importance of the cerebrospinal fluid. As far back as Hippocrates, it was thought that this "phlegm" that flooded the intracranial contents had pathological significance. However, not until the late 1800s, when Quincke introduced and popularized lumbar puncture, did physicians take an interest in the study of this fluid in relation to clinical illness. Since then a variety of techniques for obtaining cerebrospinal fluid from various sites have developed, and the relationship of cerebrospinal fluid to a variety of disease processes has received considerable study. In this volume, we have attempted to assemble reviews of some of these important developments during the past century. Chapter 1 contains a historical review of key investigations that helped shape our concepts of cerebrospinal fluid from the earliest recorded description by the author of the Edwin Smith Surgical Papyrus in the seventeenth century B. C. to contemporaries such as Kabat, Glusman, and Knaub, who introduced quantitative determinations of cerebrospinal fluid gamma globulin levels. In Chapter 2 there is a description of our current understanding of the anatomical compartment for the cerebrospinal fluid and the physiology of its formation, circulation, and absorption. Dr. Richard Leech in Chapter 3 contributes a comprehensive description of the disorders associated with excessive quanti ties of cerebrospinal fluid-commonly referred to as hydrocephalus. A variety of techniques for properly collecting and evaluating cerebrospinal fluid are detailed in Chapter 4.