Challenges And Solutions Of Oncological Hyperthermia
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Challenges And Solutions Of Oncological Hyperthermia
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Author : Andras Szasz
language : en
Publisher: Cambridge Scholars Publishing
Release Date : 2020-04-02
Challenges And Solutions Of Oncological Hyperthermia written by Andras Szasz and has been published by Cambridge Scholars Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-04-02 with Medical categories.
The next generation of oncological hyperthermia involves the medical innovation of selectively heating up the malignant cells of the body in a controlled way. The easily-distinguishable biophysical and physiological characteristics of cancer cells and their immediate environment are the focus of the targeted energy delivery of this treatment. This heterogenic heating concept breaks with the homogeneous nature of conventional hyperthermia, where an isothermally equal temperature is applied to the large surface area of a solid tumor. Due to its selectivity, the new concept enables the usage of a significantly lower energy, making it safer, less toxic, and easier to use. This book shows the challenges facing oncological hyperthermia, and highlights clinical results obtained in various countries. It also presents discussions about the theoretical basis of the method, adding some technical discussions and clarifying the most difficult points of its design. The contributions dealing with clinical results use state-of-art conventional therapies with complementary hyperthermia and show the advantages of such a combination.
Challenges In Solid Tumors And Other Cancers An Interdisciplinary Approach
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Author : Nima Rezaei
language : en
Publisher: Springer Nature
Release Date :
Challenges In Solid Tumors And Other Cancers An Interdisciplinary Approach written by Nima Rezaei and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on with categories.
Hyperthermic Oncology From Bench To Bedside
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Author : Satoshi Kokura
language : en
Publisher: Springer
Release Date : 2016-06-07
Hyperthermic Oncology From Bench To Bedside written by Satoshi Kokura and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-07 with Medical categories.
This comprehensive work broadens readers' understanding of the rudimentary mechanism of the anti-cancer effect of hyperthermia. It also presents state-of-the-art clinical outcomes by hyperthermia treatment of cancer. In the past few decades, basic and clinical research have shown through in vitro experiments that hyperthermia inhibits epithelial-mesenchymal transition (EMT), resulting in the prevention of metastasis. It also has been learned that hyperthermia shows its superior benefit when applied in combination with radiation therapy, chemotherapy, or various immunotherapies as treatments of several types of carcinoma. The chapters here from expert contributors describe the details of their research for each type of cancer. This book provides not only an overview and the current status of hyperthermia but also its future perspectives. Therefore this volume will greatly benefit oncologists, radiologists and radiology technologists, and chemotherapists who are involved in immunotherapy for all kinds of cancer.
Oncothermia Principles And Practices
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Author : Andras Szasz
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-11-23
Oncothermia Principles And Practices written by Andras Szasz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-23 with Medical categories.
Oncothermia is the next generation medical innovation that delivers selective, controlled and deep energy for cancer treatment. The basic principles for oncothermia stem from oncological hyperthermia, the oldest approach to treating cancer. Nevertheless, hyperthermia has been wrought with significant controversy, mostly stemming from shortcomings of controlled energy delivery. Oncothermia has been able to overcome these insufficiencies and prove to be a controlled, safe and efficacious treatment option. This book is the first attempt to elucidate the theory and practice of oncothermia, based on rigorous mathematical and biophysical analysis, not centered on the temperature increase. It is supported by numerous in-vitro and in-vivo findings and twenty years of clinical experience. This book will help scientists, researchers and medical practitioners in understanding the scientific and conceptual underpinnings of oncothermia and will add another valuable tool in the fight against cancer. Professor Andras Szasz is the inventor of oncothermia and the Head of St Istvan University's Biotechnics Department in Hungary. He has published over 300 papers and lectured at various universities around the world. Dr. Oliver Szasz is the managing director of Oncotherm, the global manufacturer and distributor of medical devices for cancer treatment used in Europe & Asia since the late 1980s. Dr. Nora Szasz is currently a management consultant in healthcare for McKinsey & Co.
Coronavirus Disease Covid 19 Pathophysiology Epidemiology Clinical Management And Public Health Response Volume I C
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Author : Zisis Kozlakidis
language : en
Publisher: Frontiers Media SA
Release Date : 2023-04-25
Coronavirus Disease Covid 19 Pathophysiology Epidemiology Clinical Management And Public Health Response Volume I C written by Zisis Kozlakidis and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-25 with Medical categories.
Volume I.C An outbreak of a respiratory disease first reported in Wuhan, China in December 2019 and the causative agent was discovered in January 2020 to be a novel betacoronovirus of the same subgenus as SARS-CoV and named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Coronavirus disease 2019 (COVID-19) has rapidly disseminated worldwide, with clinical manifestations ranging from mild respiratory symptoms to severe pneumonia and a fatality rate estimated around 2%. Person to person transmission is occurring both in the community and healthcare settings. The World Health Organization (WHO) has recently declared the COVID-19 epidemic a public health emergency of international concern. The ongoing outbreak presents many clinical and public health management challenges due to limited understanding of viral pathogenesis, risk factors for infection, natural history of disease including clinical presentation and outcomes, prognostic factors for severe illness, period of infectivity, modes and extent of virus inter-human transmission, as well as effective preventive measures and public health response and containment interventions. There are no antiviral treatment nor vaccine available but fast track research and development efforts including clinical therapeutic trials are ongoing across the world. Managing this serious epidemic requires the appropriate deployment of limited human resources across all cadres of health care and public health staff, including clinical, laboratory, managerial and epidemiological data analysis and risk assessment experts. It presents challenges around public communication and messaging around risk, with the potential for misinformation and disinformation. Therefore, integrated operational research and intervention, learning from experiences across different fields and settings should contribute towards better understanding and managing COVID-19. This Research Topic aims to highlight interdisciplinary research approaches deployed during the COVID-19 epidemic, addressing knowledge gaps and generating evidence for its improved management and control. It will incorporate critical, theoretically informed and empirically grounded original research contributions using diverse approaches, experimental, observational and intervention studies, conceptual framing, expert opinions and reviews from across the world. The Research Topic proposes a multi-dimensional approach to improving the management of COVID-19 with scientific contributions from all areas of virology, immunology, clinical microbiology, epidemiology, therapeutics, communications as well as infection prevention and public health risk assessment and management studies.
Cell Based Cancer Immunotherapy
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Author :
language : en
Publisher: Elsevier
Release Date : 2024-03-27
Cell Based Cancer Immunotherapy written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-27 with Science categories.
Cell-based Cancer Immunotherapy, Volume 183 provides the latest progress concerning research on anticancer cellular immunotherapies and their immunological, translation, or clinical aspects. Topics covered in this volume include Methods behind clinical DC vaccine products against glioblastoma, Fully closed and automated isolation of natural blood dendritic cells for cancer immunotherapy, Methods behind Oncolytic virus-based DC vaccines in cancer: towards a multiphase combined treatment strategy for Glioblastoma (GBM) patients, Identification of TCR repertoire patterns linked with anti-cancer immunotherapy, Training of epitope-TCR prediction models with healthy donor-derived cancer-specific T cells, Methods behind neoantigen predictions for anticancer vaccines, Methods behind CD137L-DC-EBV-VAX anticancer vaccine, and much more. Additional sections cover Gold Standard Assessment of Immunogenic Cell Death Induced by Photodynamic Therapy: From In Vitro to Tumor Mouse Models and Anti-Cancer Vaccination Strategies, Methods behind TCR analyses for colorectal cancer-associated TILs, The use of xCELLigence, Incucyte, and/or Cr/LDH/maker-release assays, Humanized mouse models for anti-cancer therapy, In vitro re-challenge of CAR T cells, Methods behind adoptively transferred tumor draining lymphocytes for anticancer immunotherapy, and A murine glioblastoma platform to test cellular therapies with the standard of care. - Provides comprehensive method articles from front-line experts on the topic of anticancer cellular immunotherapies - Provides useful schematic material and cutting-edge discussions - Presents the latest insights and future perspectives on the covered topics, along with their implications for immuno-oncology, as well as clinical perspectives
The Application Of Heat In Oncology
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Author : Devashish Shrivastava
language : en
Publisher: John Wiley & Sons
Release Date : 2023-09-13
The Application Of Heat In Oncology written by Devashish Shrivastava and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-13 with Medical categories.
THE APPLICATION OF HEAT IN ONCOLOGY Understand the use of heat to destroy tumors with this comprehensive guide Heat is an indispensable resource in the destruction of cancerous tumors to potentially treat cancers. There are also real challenges, however, involved in the total destruction of tumors without destroying healthy tissue surrounding the tumor in the process. A detailed understanding of the propagation of thermal energy, induced heating, and tissue responses to heat is required to safely and successfully apply heat-based technologies in clinical oncology. The Application of Heat in Oncology supplies this understanding, with a thorough, comprehensive overview of the principle and practice involved. Offering both a detailed introduction to the physics and thermodynamics of induced heat and an analysis of its clinical applications, this is an essential resource for clinicians, technicians, and others in oncological practice. The Application of Heat in Oncology readers will also find: Guidelines for applying heat both safely and effectively Detailed discussion of topics including energy delivery (e.g., via RF, MW, ultrasound, laser, cryoagents, hyperthermia, nanoparticles, etc.), temperature assessment, damage assessment, image guidance, and more Summary of current practice along with suggestions for future areas of technological improvement The Application of Heat in Oncology is ideal for all clinicians working in the field of cancer treatment, including medical students, residents, researchers, engineers, radiologists, surgeons, and more.
Cancer Strategy Worldwide Solutions To A Worldwide Problem
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Author : Patrick Bishop
language : en
Publisher: BookLocker.com, Inc.
Release Date : 2025-04-10
Cancer Strategy Worldwide Solutions To A Worldwide Problem written by Patrick Bishop and has been published by BookLocker.com, Inc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-04-10 with Medical categories.
"Cancer Strategy - Critical Thinking" by Patrick Bishop is a comprehensive, empowering guide to navigating the complex world of cancer care, blending scientific insight with holistic and integrative approaches. Spanning over 400 pages, the book targets patients, caregivers, and practitioners, offering a roadmap to understand cancer biology, evaluate treatment options, and adopt preventive strategies for improved outcomes. Bishop, a serial entrepreneur and cancer researcher driven by personal losses—his grandfather, father, and brother all succumbed to cancer—infuses the text with 19 years of research and a heartfelt call for thoughtful decision-making. The book opens with a prologue on the "biology of belief," where Bishop explores how faith and positive thinking influence health, rooted in his Christian convictions. This sets the tone for a mind-body-spirit approach, suggesting that mental and spiritual resilience can complement physical healing. The introduction frames cancer as both a medical and personal journey, advocating for a balanced strategy that integrates conventional treatments like chemotherapy and surgery with non-toxic alternatives such as acupuncture, Gerson Therapy, and detoxification. Key sections delve into cancer’s biological underpinnings, explaining the immune system’s role in fighting malignant cells, the multistage process of carcinogenesis (initiation, promotion, progression), and the significance of early detection through screenings like mammograms and colonoscopies. Bishop highlights preventive lifestyle factors—diet (e.g., ketogenic, plant-based), exercise, sleep, and stress reduction—while introducing the unique oral-systemic connection, linking dental health issues like root canals to cancer risk via chronic inflammation. A central feature is an extensive treatment catalog, detailing over 50 therapies with their toxicity levels (low, moderate, high) and FDA approval status as of December 2024. Conventional options (e.g., radiation, immunotherapy) sit alongside integrative methods (e.g., hyperbaric oxygen, Ayurveda), each evaluated for benefits and limitations to aid informed choices. Bishop emphasizes personalized medicine, spotlighting genetic testing and targeted therapies to tailor care to individual needs. The book also tackles practical and ethical challenges: building a multidisciplinary care team (oncologists, naturopaths, caregivers), addressing financial toxicity—the hidden cost burden of treatment—and navigating survivorship, palliative, and end-of-life care. A critique of the pharmaceutical-driven healthcare system argues for a shift from profit-focused drug dependency to prevention-focused wellness. Looking forward, Bishop explores emerging technologies like liquid biopsies, AI diagnostics, and gene editing, blending them with holistic practices to envision a future of patient-centered cancer care. Ultimately, "Cancer Strategy - Critical Thinking" empowers readers with knowledge, hope, and resilience, urging a proactive, integrative approach to conquer cancer’s challenges.
Critical Issues In Head And Neck Oncology
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Author : Jan B. Vermorken
language : en
Publisher: Springer Nature
Release Date : 2025-06-24
Critical Issues In Head And Neck Oncology written by Jan B. Vermorken and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-24 with Medical categories.
This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field, this book reviews state-of-the-art knowledge with emphasis on multidisciplinary decision making and management of head and neck cancer. Significant detail is provided on a wide range of topics including: oral potentially malignant disorders, cell-based assays for drug discovery and drug evaluation, the role of precision medicine (genomics and beyond), innovations in systemic therapy (including metronomic chemotherapy and immunotherapy), surgery (including partial laryngeal surgery and quality of reconstruction) and radiotherapy (including FLASH-therapy) in different disease settings taking into account their impact on benefit/risk ratio. In addition, specific topics such as hypoxia, hyperthermia, intratumoral drug administration, noninvasive biomarkers, local therapy in metastatic head and neck cancer, sentinel lymph node biopsy in cN0 early-stage oral cavity cancer, prognostic factors in HPV-positive oropharyngeal cancer, molecular characterization of salivary gland cancer (including implications for treatment) and strategies to improve outcome in salivary duct carcinoma are discussed. All disciplines involved in the treatment of head and neck cancer are covered with a focus on translation into daily practice. The 9th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment and care of patients with head and neck cancer.
Journal Of The National Cancer Institute
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Author :
language : en
Publisher:
Release Date : 1993
Journal Of The National Cancer Institute written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Cancer categories.