Charged Particles In Oncology
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Charged Particles In Oncology
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Author : Marco Durante
language : en
Publisher: Frontiers Media SA
Release Date : 2018-01-31
Charged Particles In Oncology written by Marco Durante and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-31 with categories.
High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet’s surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.
Charged Particles In Oncology
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Author :
language : en
Publisher:
Release Date : 2018
Charged Particles In Oncology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018 with categories.
High-energy charged particles represent a cutting-edge technique in radiation oncology. Protons and carbon ions are used in several centers all over the world for the treatment of different solid tumors. Typical indications are ocular malignancies, tumors of the base of the skull, hepatocellular carcinomas and various sarcomas. The physical characteristics of the charged particles (Bragg peak) allow sparing of much more normal tissues than it is possible using conventional X-rays, and for this reason all pediatric tumors are considered eligible for protontherapy. Ions heavier than protons also display special radiobiological characteristics, which make them effective against radioresistant and hypoxic tumors. On the other hand, protons and ions with high charge (Z) and energy (HZE particles) represent a major risk for human space exploration. The main late effect of radiation exposure is cancer induction, and at the moment the dose limits for astronauts are based on cancer mortality risk. The Mars Science Laboratory (MSL) measured the dose on the route to Mars and on the planet's surface, suggesting that a human exploration missions will exceed the radiation risk limits. Notwithstanding many studies on carcinogenesis induced by protons and heavy ions, the risk uncertainty remains very high. In this research topic we aim at gathering the experiences and opinions of scientists dealing with high-energy charged particles either for cancer treatment or for space radiation protection. Clinical results with protons and heavy ions, as well as research in medical physics and pre-clinical radiobiology are reported. In addition, ground-based and spaceflight studies on the effects of space radiation are included in this book. Particularly relevant for space studies are the clinical results on normal tissue complications and second cancers. The eBook nicely demonstrates that particle therapy in oncology and protection of astronauts from space radiation share many common topics, and can learn from each other.
Proton And Charged Particle Radiotherapy
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Author : Thomas F. De Laney
language : en
Publisher: Lippincott Williams & Wilkins
Release Date : 2008
Proton And Charged Particle Radiotherapy written by Thomas F. De Laney and has been published by Lippincott Williams & Wilkins this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Medical categories.
This volume is the first comprehensive and practical clinical reference on proton and charged particle radiotherapy. The first half of the book explains the treatment delivery systems used, offers detailed guidance on treatment planning techniques, examines key clinical issues in proton radiotherapy, and reviews recent experience with heavier charged particle radiotherapy. The second half of the book offers "how-to" information on treatment of pediatric tumors, lymphomas, and tumors of the central nervous system, eye, skull base, cervical spine, bone and soft tissue, paranasal sinus, nasal cavity, nasopharynx, oropharynx, oral cavity, salivary glands, prostate, lung, gastrointestinal tract, female reproductive tract, and breast. More than 100 full-color illustrations complement the text.
Monte Carlo In Heavy Charged Particle Therapy
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Author : Pablo Cirrone
language : en
Publisher: CRC Press
Release Date : 2023-11-08
Monte Carlo In Heavy Charged Particle Therapy written by Pablo Cirrone and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-08 with Science categories.
This book explores the current difficulties and unsolved problems in the field of particle therapy and, after analysing them, discusses how (and if) innovative Monte Carlo approaches can be used to solve them. Each book chapter is dedicated to a different sub-discipline, including multi-ion treatments, flash-radiotherapy, laser-accelerated beams, nanoparticles effects, binary reactions to enhance radiobiology, and space-related issues. This is the first book able to provide a comprehensive insight into this exciting field and the growing use of Monte Carlo in medical physics. It will be of interest to graduate students in medicine and medical physics, in addition to researchers and clinical staff. Key Features: Explores the exciting and interdisciplinary topic of Monte Carlo in particle therapy and medicine. Addresses common challenges in the field. Edited by an authority on the subject, with chapter contributions from specialists. Pablo Cirrone is a medical physicist and researcher at the Laboratori Nazionali del Sud of INFN, Italy, where he supports and coordinates various experimental groups. Dr. Cirrone is an expert in the use of proton and ion in radiation treatment and of absolute and relative dosimetry in electron, photon and ion beam. He is an expert in the development and test of detectors for medical applications, of the production and use of laser-driven beams for medical and multidisciplinary applications and recipient of the Michael Gotein Award. He is active on many scientific committees and organizes national and international conferences. Giada Petringa is a researcher at the Laboratori Nazionali del Sud of INFN, Italy. Dr. Petringa has a professional experience in the field of Monte Carlo simulations for medical applications, dosimetry, microdosimetry, and diagnostics with conventional and laser-driven proton beams. In 2019 she had a MSCA-IF-2019 (Marie Sklodowska-Curie Actions-Individual Fellowship) grant funded by the European Community in the framework of the H2020 program. She is a member of the Editorial Board of the international journal Physica Medica - European Journal of Medical. She organized more than fifteen international Geant4 Schools. She is an official member of the Geant4 code Collaboration at CERN since 2019. She is a code developer, and she collaborates to maintain two of the official examples of the code.
Proton And Charged Particle Radiotherapy
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Author : Thomas F. DeLaney
language : en
Publisher:
Release Date : 2015-04-24
Proton And Charged Particle Radiotherapy written by Thomas F. DeLaney and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-04-24 with Cancer categories.
This volume is the first comprehensive and practical clinical reference on proton and charged particle radiotherapy. The first half of the book explains the treatment delivery systems used, offers detailed guidance on treatment planning techniques, examines key clinical issues in proton radiotherapy, and reviews recent experience with heavier charged particle radiotherapy. The second half of the book offers ""how-to"" information on treatment of pediatric tumors, lymphomas, and tumors of the central nervous system, eye, skull base, cervical spine, bone and soft tissue, paranasal sinus, nasal c.
Next Evolutions In Charged Particle Therapy
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Author : Thomas Tessonnier
language : en
Publisher: Frontiers Media SA
Release Date : 2022-08-03
Next Evolutions In Charged Particle Therapy written by Thomas Tessonnier and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-08-03 with Medical categories.
Particle Radiotherapy
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Author : Arabinda Kumar Rath
language : en
Publisher: Springer
Release Date : 2016-03-10
Particle Radiotherapy written by Arabinda Kumar Rath and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-10 with Medical categories.
The results of decades of research and development are providing compelling evidence about the efficacy of radiation therapy with proton and carbon ion beams to achieve superior complication free tumor control leading to a world-wide rapid growth in their clinical use. This book contains comprehensive reviews of the state of the art of the technology and physics of heavy charge particle therapy by the experts from the leading cancer centers of world that will be valuable as a practical guide for radiation therapy professionals interested in these modalities.
Principles And Practice Of Particle Therapy
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Author : Timothy D. Malouff
language : en
Publisher: Wiley-Blackwell
Release Date : 2022
Principles And Practice Of Particle Therapy written by Timothy D. Malouff and has been published by Wiley-Blackwell this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022 with Medical categories.
"While the fundamental physical principles that provide the basis for particle therapy are well established, the practical use of these principles is continually evolving as the use of particle therapy continues to grow. Once a novelty, particle therapy is now widely available in many parts of the world. Proton therapy is now a routine option for many patients, and multiple facilities in different countries are treating patients with carbon ion therapy as data is gathered to determine the best clinical use of this technology. Pharmaceutical improvements have also revitalized neutron beam therapy when used for boron neutron capture therapy (BNCT), joining several fast neutron therapy (FNT) centers around the world. Compared to traditional photon and electron radiation therapy, heavier particles have some desirable physical characteristics that allow for safer and more effective treatments in certain scenarios. Heavier particles such as neutrons, protons, and carbon ions offer increased linear energy transfer (LET) and relative biological effectiveness (RBE). Heavier charged particles have beneficial dosimetric advantages such as decreased distal, lateral, and integral dose, and neutron beams can be used to generate targeted therapeutic secondary particles."--
Proton And Carbon Ion Therapy
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Author : C-M Charlie Ma
language : en
Publisher: CRC Press
Release Date : 2012-10-09
Proton And Carbon Ion Therapy written by C-M Charlie Ma and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-09 with Science categories.
Proton and Carbon Ion Therapy is an up-to-date guide to using proton and carbon ion therapy in modern cancer treatment. The book covers the physics and radiobiology basics of proton and ion beams, dosimetry methods and radiation measurements, and treatment delivery systems. It gives practical guidance on patient setup, target localization, and treatment planning for clinical proton and carbon ion therapy. The text also offers detailed reports on the treatment of pediatric cancers, lymphomas, and various other cancers. After an overview, the book focuses on the fundamental aspects of proton and carbon ion therapy equipment, including accelerators, gantries, and delivery systems. It then discusses dosimetry, biology, imaging, and treatment planning basics and provides clinical guidelines on the use of proton and carbon ion therapy for the treatment of specific cancers. Suitable for anyone involved with medical physics and radiation therapy, this book offers a balanced and critical assessment of state-of-the-art technologies, major challenges, and the future outlook of proton and carbon ion therapy. It presents a thorough introduction for those new to the field while providing a helpful, up-to-date reference for readers already using the therapy in clinical settings.
Heavy Particle Radiotherapy
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Author : M Raju
language : en
Publisher: Academic Press
Release Date : 1980-01-28
Heavy Particle Radiotherapy written by M Raju and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980-01-28 with Health & Fitness categories.
Heavy Particle Radiotherapy covers the significant advances in the application of radiotherapy to cancer treatment. This book is composed of eight chapters that focus on the performance of several heavy particles. The introductory chapters describe the radiobiological phenomena of interest in radiotherapy and their modifications with increasing linear energy transfer. The remaining chapters discuss the physical aspects, cellular effects, and radiotherapy potential of heavy particles, including neutrons, protons, helium and heavy ions, and negative pions.