Chemical Immunology
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Physical And Chemical Methods
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Author : Curtis A. Williams
language : en
Publisher: Academic Press
Release Date : 2014-05-12
Physical And Chemical Methods written by Curtis A. Williams and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-12 with Medical categories.
Methods in Immunology: Volume II, Physical and Chemical Methods is a collection of papers dealing with electrophoresis, analytical ultracentrifugation, dialysis, ultrafiltration, cellulose ion exchangers, and chromatographic separation of macromolecules on porous gels. Some papers explain the applications of radioisotopes, optical analysis, and chemical analysis of proteins, carbohydrates, lipids, and nucleic acid. One paper describes the theory of electro-migration. Factors such as electrical charge or frictional coefficients govern the rate of migration of charged particles in an electric field. The differences found in their velocities can be used to separate substances or analyze them. Mobility is a characteristic property of molecules and can also be influenced by the composition of the medium or solution. Dialysis separates solvents too large to diffuse through a barrier from smaller solutes; ultrafiltration (reverse osmosis) forces solvent and solutes up to a certain critical size through the barrier by a high pressure on one side. The book notes that the membrane never becomes plugged in dialysis because of some opposite movement of the solvent. Another paper points out that the significance of radioactive tracers in immunochemistry employed to identify and label macromolecules functioning as antigens and antibodies. The collection can prove valuable to bio-chemists, cellular biologists, micro-biologists, developmental biologists, and scientists involved in immunological research.
Chemical Immunology
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Author :
language : en
Publisher:
Release Date : 2002
Chemical Immunology written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2002 with Allergy categories.
Addressing Roles For Glycans In Immunology Using Chemical Biology
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Author : Matthew S. Macauley
language : en
Publisher: Frontiers Media SA
Release Date : 2020-07-17
Addressing Roles For Glycans In Immunology Using Chemical Biology written by Matthew S. Macauley and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-17 with categories.
Antigenic Determinants And Immune Regulation
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Author :
language : en
Publisher:
Release Date : 1989
Antigenic Determinants And Immune Regulation written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989 with Antigenic Determinants categories.
Methods In Immunology And Immunochemistry Physical And Chemical Methods
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Author : Curtis Alvin Williams
language : en
Publisher:
Release Date : 1968
Methods In Immunology And Immunochemistry Physical And Chemical Methods written by Curtis Alvin Williams and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Immunity categories.
Chemical Mediators Of Inflammation And Immunity
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Author : Stanley Cohen
language : en
Publisher:
Release Date : 1986
Chemical Mediators Of Inflammation And Immunity written by Stanley Cohen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Immune response categories.
From the Preface: This volume deals with chemical and molecular aspects of inflammatory responses that may be induced by immunologic or nonimmunologic means. Certain purely immunologic factors such as Interleukin 2 are included because they can potentiate immune responses that have important inflammatory consequences...We have attempted to stress those mediators and those reactions that appear to play a critical role in tissue injury and repair, as well as protection against disease processes.
Physical And Chemical Methods
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Author : Curtis A. Williams
language : en
Publisher:
Release Date : 1968
Physical And Chemical Methods written by Curtis A. Williams and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1968 with Immunochemistry categories.
Catalytic Antibodies
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Author : Sudhir Paul
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2000-01-01
Catalytic Antibodies written by Sudhir Paul and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-01-01 with Medical categories.
This volume addresses fundamental questions concerning the immunological genesis of the catalytic activity in antibodies, its relationship with classical antigen binding activity, and the biochemical mechanisms involved in catalysis. The contents reflect three main challenges in the field, i.e. to delineate the biological functions of catalytic antibodies in autoimmune disease; to isolate therapy-grade antibody catalysts with sufficient specificity and turnover to permit rapid removal of microbial and tumor antigens; and to develop immunogens that recruit immature catalyst-producing B cells into the clonal selection pathway and induce adaptive improvements of the catalytic function. Well-edited and up-to-date, this book reviews the current knowledge in the field and explores ways by which natural and engineered catalytic activities can be harnessed for medical applications. It should therefore be of special interest to immunologists, biochemists, biotechnologists, rheumatologists and pathologists.
Molecular Aspects Of Innate And Adaptive Immunity
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Author : Kenneth B M Reid
language : en
Publisher: Royal Society of Chemistry
Release Date : 2008-09-29
Molecular Aspects Of Innate And Adaptive Immunity written by Kenneth B M Reid and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-29 with Medical categories.
The understanding, at the molecular level, of the interactions between innate and adaptive arms of the immune system is currently a hot topic, particularly to those interested in immunology - especially susceptibility to infectious diseases. This book provides a survey of topics, in the area of innate and adaptive immunity, which have been researched within the MRC Immunochemistry Unit, at Oxford University, over a period of forty years. The topics include: " antibody structure - for which the first Director of the Immunochemistry Unit, Professor RR Porter, was awarded a Nobel prize in 1972 " the characterization of membrane proteins on lymphoid cells - leading to the concept of these molecules belonging to an immunoglobulin super family " the proteins of the human serum complement system - one of the body's major defences against microbial infection " the human cell -surface integrins and the hyaluronan- binding proteins, which are involved in regulation of inflammation at cell surfaces and within the extracellular matrix " the family of collectin molecules - containing distinct globular carbohydrate -binding domains linked to collagen-like regions - which play important roles in innate immunity in the lungs and bloodstream by immediate recognition and clearance of microbial pathogens Each chapter in the book gives a brief historical background to a topic and then provides a survey of recent advances in the field and are written by internationally recognised renowned experts. The theme running through the chapters is that of protein structure-function relationships - including, amongst others, descriptions of quaternary structures of large oligomeric proteins, of Factor H and C1q binding to specific ligands, and of the chemistry of the mechanism of catalysis of covalent binding of activated C3 and C4 proteins to nucleophilic groups on microbial surfaces. In several chapters excellent descriptions are given with respect to how the immune system can be recruited to combat microbial infection - via proteins of both the innate and adaptive immune systems. The book also includes notable chapters which are excellent examples of the importance of how the isolation, characterisation, protein engineering and crystallisation has resulted in a full understanding of complex protein-protein interactions involved in the recognition and triggering events of important sections of the immune system: -Structure and Function of the C1 Complex - GÚrard J. Arlaud -Chemical Engineering of Therapeutic Antibodies - George T Stevenson -Leukocyte surface proteins - purification and characterisation - A. Neil Barclay -Cell Surface Integrins - Suet-Mien Tan and S.K. Alex Law This book is aimed primarily at established senior research scientists, postdoctoral research scientists and PhD students who have an interest in proteins of the immune system. However, the wide range of immunity system topics, while staying broadly within innate/adaptive immunity will also appeal to a wider audience.
Blood Group Substances
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Author : Elvin A. Kabat
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Blood Group Substances written by Elvin A. Kabat and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Blood Group Substances: Their Chemistry and Immunochemistry focuses on the characteristics, reactions, sources, and transformations of blood group substances. The book first offers information on human blood group factors and the methods and reagents used in testing for blood group antibodies and antigens. Topics include autoantibody formation and hemolytic anemia, panagglutinable erythrocytes, effects of temperature on hemagglutination, and effects of periodate on blood group substances. The text also ponders on the sources and purification of blood group substances. The publication examines the chemical and immunochemical characterization of blood group substances and immunochemical similarities and differences among blood group substances from various species. The text then takes a look at antibodies to blood group substances and their biological effects, including purification and concentration of blood group antibodies; studies with antibodies labeled with radioactive isotopes; and passage of antibodies through the placenta. The manuscript is a valuable reference for readers interested in blood group substances.