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Chemistry Of Nucleosides And Nucleotides


Chemistry Of Nucleosides And Nucleotides
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The Chemistry Of Nucleosides And Nucleotides


The Chemistry Of Nucleosides And Nucleotides
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Author : A. M. Michelson
language : en
Publisher:
Release Date : 1963

The Chemistry Of Nucleosides And Nucleotides written by A. M. Michelson and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1963 with Nucleic acids categories.




Chemistry Of Nucleosides And Nucleotides


Chemistry Of Nucleosides And Nucleotides
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Author : L.B. Townsend
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-07

Chemistry Of Nucleosides And Nucleotides written by L.B. Townsend and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-07 with Science categories.


The present volume is the first of a projected four-volume treatise. This volume contains the following chapters: "Synthesis and Reaction of Pyrimidine Nucleosides," "Synthesis and Properties of Purine Nucleosides and Nucleotides," and "Synthesis and Properties of Oligonucleotides." These three chapters were selected for inclusion in Volume I because the areas have provided the basis and impetus for the initiation and development of the other areas of research, which will be described in subsequent volumes. Each chapter is rather comprehensive in nature and should provide a ready reference source for not only the novice but also the experienced investigator or researcher. The chapters have been prepared by authors with considerable experience in each particular area of research, and this has resulted in a lucid presentation of each well-defined area. These volumes were designed with medicinal chemists, medicinal organic chemists, organic chemists, carbohydrate chemists, physical chemists, and biological chemists in mind. However, because of the tremendous recent interest in this research area owing to the biological and chemotherapeutic evaluation of nucleosides and nucleotides as anticancer, antiviral, and antiparasitic agents, these volumes should also be valuable additions to the libraries of virologists, biochemical pharmacologists, oncologists, and pharmacologists. We would like to thank the authors for their enthusiasm and help in making these volumes available to the scientific community.



Chemistry And Biology Of Nucleosides And Nucleotides


Chemistry And Biology Of Nucleosides And Nucleotides
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Author : Robert Harmon
language : en
Publisher: Academic Press
Release Date : 2012-12-02

Chemistry And Biology Of Nucleosides And Nucleotides written by Robert Harmon and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Chemistry and Biology of Nucleosides and Nucleotides is a collection of papers presented at the symposium on the Chemistry and Biology of Nucleosides and Nucleotides, held on August 30-September 1, 1976, as part of the San Francisco Centennial Meeting of the Carbohydrate Division of the American Chemical Society. Contributors explore the chemistry and biology of nucleosides and nucleotides ans well as the different chemical and instrumental techniques used in their synthesis. This book is comprised of 28 chapters and begins by describing the synthesis of a gene and its introduction into a biological system where it proved to be functional. The synthesis of nucleosides and nucleotides with anticancer and antiviral activity is also discussed, along with the rationale for the design and synthesis of such compounds. Simple models of nucleic acid interactions are described. Subsequent chapters explore the chemistry and biological activity of C-nucleosides related to pseudouridine and of some nucleoside analogs active against tumor cells; the selectivity and stereospecificity of the ribosylation reaction; synthesis of C-glycosyl thiazoles; and C-nucleoside isosteres of some nucleoside antibiotics. This monograph will serve as reference and source material for many workers in biomedical research as teaching material for instructors of advanced science courses.



Chemistry Of Nucleosides And Nucleotides


Chemistry Of Nucleosides And Nucleotides
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Author : L.B. Townsend
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Chemistry Of Nucleosides And Nucleotides written by L.B. Townsend and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Science categories.


This third of four volumes continues the work of its well-received predecessors by providing comprehensive articles on specific lines of research. All volumes are written with medicinal chemists, organic chemists, physical chemists, and biological chemists in mind. Additionally, with the spate of recent research on the anticancer, antiviral, and antiparasitic properties of nucleosides and nucleotides, the volumes will interest oncologists, virologists, and pharmacologists.



Chemistry Of Nucleosides And Nucleotides


Chemistry Of Nucleosides And Nucleotides
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Author : Leroy B. Townsend
language : en
Publisher:
Release Date : 1991

Chemistry Of Nucleosides And Nucleotides written by Leroy B. Townsend and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1991 with categories.




Nucleosides Nucleotides And Their Biological Applications


Nucleosides Nucleotides And Their Biological Applications
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Author : Janet L Rideout
language : en
Publisher: Academic Press
Release Date : 2012-12-02

Nucleosides Nucleotides And Their Biological Applications written by Janet L Rideout and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.


Nucleosides, Nucleotides, and Their Biological Applications contains the proceedings of the Fifth International Round Table on Nucleosides, Nucleotides, and Their Biological Applications held at Research Triangle Park, North Carolina on October 20-22, 1982. Contributors focus on the biological applications of nucleosides and nucleotides, along with advances in synthetic chemistry. Topic range from fast-moving biochemical subjects such as the 2',5'-oligoadenylates and their relationship to interferons; adenosine and adenine nucleotide receptors; and nucleosides with selective antiviral action. This volume is organized into 11 chapters and begins with an overview of nucleosides that are used as antiviral agents and their mechanism of action, including idoxuridine, vidarabine, and trifluridine. The discussion then shifts to the chemical and biological properties of nucleosides of purines and ring analogs; 2'-fluoroarabinosyl pyrimidines and purine-like C-nucleosides; and the potential of 2',5'-oligoadenylates as chemotherapeutic agents. The reader is also introduced to receptors for adenosine and adenine nucleotides; the function of pyrrolo[2,3-d]pyrimidine nucleosides in polynucleotides; and unusual nucleoside synthons and oligonucleotide synthesis. A chapter on the synthesis of versatile C-nucleoside precursors and certain C-nucleosides concludes the book. This book will be of value to chemists, biologists, and those with an interest in nucleosides and nucleotides.



Organic Chemistry Of Nucleic Acids


Organic Chemistry Of Nucleic Acids
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Author : N. Kochetkov
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Organic Chemistry Of Nucleic Acids written by N. Kochetkov and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.


The study of nucleic acids is one of the most rapidly developing fields in modern science. The exceptionally important role of the nucleic acids as a key to the understanding of the nature of life is reflected in the enormous number of published works on the subject, including many outstanding monographs and surveys. The pathways of syn thesis and metabolism of nucleic acid,s and the many and varied biological functions of these biopolymers are examined with the utmost detail in the literature. Nearly as much attention has been paid to the macromolecular chemistry of the nucleic acids: elucidation of the size and shape of their molecules, the study of the physicochemical properties of their solutions, and the appropriate methods to be used in such research. The surveys of the chemistry of nucleic acids which have been published so far deal almost entirely with their synthesis and, in particular, with the synthetic chemistry of monomers (nucleosides and nucleotides) ; less attention has been paid to the synthesis of poly nucleotides. There is yet another highly important aspect of the chemistry of nucleic acids which is still in the formative stage, the study of the reactivity of nucleic acid macromolecules and their components. This can make an important contribution to the deter mination of the structure of these remarkable biopolymers and to the correct understanding of their biological functions.



Purines Pyrimidines And Nucleotides And The Chemistry Of Nucleic Acids


Purines Pyrimidines And Nucleotides And The Chemistry Of Nucleic Acids
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Author : T. L. V. Ulbricht
language : en
Publisher: Elsevier
Release Date : 2016-06-03

Purines Pyrimidines And Nucleotides And The Chemistry Of Nucleic Acids written by T. L. V. Ulbricht and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-06-03 with Science categories.


Purines, Pyrimidines and Nucleotides and the Chemistry of Nucleic Acids is a five-chapter text that presents a simple introduction to the basic chemistry of purines and pyrimidines and their derivatives. The opening chapters describe the general properties, reactions, and synthesis of purines and pyrimidines. The next chapter deals with the structure, synthesis, mechanism, and stereochemistry of nucleosides and their analogues. These topics are followed by a discussion on the reactions and biosynthesis of nucleotides. The final chapter focuses on the structure and biosynthesis of DNA, RNA, and other nucleic acids. This book is of value to organic chemists and biochemists, as well as researchers in the allied fields.



Chemistry And Biology Of Nucleosides And Nucleotides


Chemistry And Biology Of Nucleosides And Nucleotides
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Author : Robert E. Harmon
language : en
Publisher:
Release Date : 1978

Chemistry And Biology Of Nucleosides And Nucleotides written by Robert E. Harmon and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1978 with Nucleosides categories.




Chemistry Of Nucleic Acids


Chemistry Of Nucleic Acids
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Author : Harri Lönnberg
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-08-10

Chemistry Of Nucleic Acids written by Harri Lönnberg and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-10 with Science categories.


Life in all its forms is based on nucleic acids which store and transfer genetic information. The book addresses the main aspects of synthesis, hydrolytic stability, solution equilibria of nucleosides and nucleotides as well as base modifications of nucleic acids. The author further describes their structural analogues used as therapeutic drugs, such as antivirals and anticancer agents, and prodrug strategies of nucleotides.