Chromatin Dynamics In Cellular Function
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Chromatin Dynamics In Cellular Function
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Author : Brehon Laurent
language : en
Publisher: Springer
Release Date : 2014-10-19
Chromatin Dynamics In Cellular Function written by Brehon Laurent and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-19 with Science categories.
This volume includes timely reviews of several aspects of chromatin biology written by scientists at the forefront of this rapidly moving field. Topics covered include the structure and function of protein modules within chromatin-remodeling proteins, newly characterized histone modifications (methylation, ubiquitylation) and their functional consequences, transcription and histone dynamics, roles of chromatin remodeling factors in DNA replication and repair, and current models of nucleosome-remodeling mechanisms.
Chromatin Regulation And Dynamics
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Author : Anita Göndör
language : en
Publisher: Academic Press
Release Date : 2016-10-25
Chromatin Regulation And Dynamics written by Anita Göndör and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-25 with Science categories.
Chromatin Regulation and Dynamics integrates knowledge on the dynamic regulation of primary chromatin fiber with the 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes. The final chapters discuss the many ways chromatin dynamics can synergize to fundamentally contribute to the development of complex diseases. Chromatin dynamics, which is strategically positioned at the gene-environment interface, is at the core of disease development. As such, Chromatin Regulation and Dynamics, part of the Translational Epigenetics series, facilitates the flow of information between research areas such as chromatin regulation, developmental biology, and epidemiology by focusing on recent findings of the fast-moving field of chromatin regulation. Presents and discusses novel principles of chromatin regulation and dynamics with a cross-disciplinary perspective Promotes crosstalk between basic sciences and their applications in medicine Provides a framework for future studies on complex diseases by integrating various aspects of chromatin biology with cellular metabolic states, with an emphasis on the dynamic nature of chromatin and stochastic principles Integrates knowledge on the dynamic regulation of primary chromatin fiber with 3D nuclear architecture, then connects related processes to circadian regulation of cellular metabolic states, representing a paradigm of adaptation to environmental changes
Introduction To Epigenetics
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Author : Renato Paro
language : en
Publisher: Springer Nature
Release Date : 2021-03-23
Introduction To Epigenetics written by Renato Paro and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-23 with Science categories.
This open access textbook leads the reader from basic concepts of chromatin structure and function and RNA mechanisms to the understanding of epigenetics, imprinting, regeneration and reprogramming. The textbook treats epigenetic phenomena in animals, as well as plants. Written by four internationally known experts and senior lecturers in this field, it provides a valuable tool for Master- and PhD- students who need to comprehend the principles of epigenetics, or wish to gain a deeper knowledge in this field. After reading this book, the student will: Have an understanding of the basic toolbox of epigenetic regulation Know how genetic and epigenetic information layers are interconnected Be able to explain complex epigenetic phenomena by understanding the structures and principles of the underlying molecular mechanisms Understand how misregulated epigenetic mechanisms can lead to disease
Chromatin Structure And Dynamics
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Author : J. Zlatanova
language : en
Publisher: Gulf Professional Publishing
Release Date : 2004
Chromatin Structure And Dynamics written by J. Zlatanova and has been published by Gulf Professional Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.
Biological processes that replicate, preserve and use the genetic information encoded in DNA must operate in the context of chromatin, a highly organized complex of DNA and proteins. These proteins do not merely package the DNA in the tiny volume of the nucleus, but impart the structure the ability to change according to the requirements of the specific process the DNA is involved in. Moreover, chromatin structure is used by the cell to control the activity of DNA. In this volume the basics of chromatin structure and dynamics are presented by established experts in the field.
Protein Complexes That Modify Chromatin
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Author : Jerry L. Workman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Protein Complexes That Modify Chromatin written by Jerry L. Workman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
An early view of eukaryotic chromosomes was that of static structures, which stored DNA not in use within a given cell type. It was thought that packaging of DNA into higher levels of chromatin structure would suffice to repress gene expression and that the challenge to the cell would be to rescue specific sequences from these structures. The exten sive packaging of inactive DNA was considered the primary difference between eukaryotic and prokaryotic genomes and except for that point both would be similarly regulated by cis-acting sequences and trans acting factors. Our view of eukaryotic chromosomes has evolved dra matically over the last decade. The picture of chromosomes that is emerging is that of dynamic breathing organelles actively regulating the flow of genetic information from the genome. Indeed chromatin is so fluid that even maintaining gene quiescence is an active process and is tightly regulated. Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobi lize nucleosomes or stabilize nucleosomes. Awide variety of such com plexes have now been described. Some are abundant and may play glo bal roles in chromosome fluidity and function. Others are more rare and specialized for specific functions at discreet loci. Moreover, several complexes share biochemical activities and genetic studies suggest overlapping functions in vivo. Many components of these complexes were first revealed in genetic screens, while others were discovered by novel cell biological or biochemical approaches.
Chromatin
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Author : Ralf Blossey
language : en
Publisher: CRC Press
Release Date : 2017-08-04
Chromatin written by Ralf Blossey and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-04 with Computers categories.
An invaluable resource for computational biologists and researchers from other fields seeking an introduction to the topic, Chromatin: Structure, Dynamics, Regulation offers comprehensive coverage of this dynamic interdisciplinary field, from the basics to the latest research. Computational methods from statistical physics and bioinformatics are detailed whenever possible without lengthy recourse to specialized techniques.
Chromatin Stability And Dynamics Targeting And Recruitment Of Chromatin Modifiers
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Author : Sara Farrona
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-27
Chromatin Stability And Dynamics Targeting And Recruitment Of Chromatin Modifiers written by Sara Farrona and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-27 with Science categories.
Chromatin Structure And Function
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Author : Claudio Nicolini
language : en
Publisher: Springer
Release Date : 1979
Chromatin Structure And Function written by Claudio Nicolini and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1979 with Science categories.
Papers presented at the 1978 NATO Advanced Study Institute conference on chromatin.
Chromatin And Disease
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Author : Tapas K. Kundu
language : en
Publisher: Springer
Release Date : 2010-11-11
Chromatin And Disease written by Tapas K. Kundu and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-11 with Science categories.
This book includes a collection of articles with the broad theme of disease connection to chromatin structure and function. It elaborates on the molecular pharmacology of the drugs targeting chromatin structure and its components. The book contains up-to-date information about the chromatin structure and chromatin related diseases and drug functions. This work is the first endeavor to present different aspects encompassing the above theme.
Nuclear Architecture And Dynamics
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Author : Christophe Lavelle
language : en
Publisher: Academic Press
Release Date : 2017-10-27
Nuclear Architecture And Dynamics written by Christophe Lavelle and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-10-27 with Medical categories.
Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds