Chromosome Structure And Aberrations
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Chromosome Structure And Aberrations
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Author : Tariq Ahmad Bhat
language : en
Publisher: Springer
Release Date : 2017-02-08
Chromosome Structure And Aberrations written by Tariq Ahmad Bhat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-08 with Medical categories.
This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.
Chromosome Structure And Aberrations
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Author : Tariq Ahmad Bhat
language : en
Publisher: Springer
Release Date : 2018-09-11
Chromosome Structure And Aberrations written by Tariq Ahmad Bhat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-11 with Medical categories.
This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.
Chromosome Structure And Aberrations
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Author : Tariq Ahmad Bhat
language : en
Publisher: Springer
Release Date : 2017-02-17
Chromosome Structure And Aberrations written by Tariq Ahmad Bhat and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-17 with Medical categories.
This book is a compilation of various chapters contributed by a group of leading researchers from different countries and covering up to date information based on published reports and personal experience of authors in the field of cytogenetics. Beginning with the introduction of chromosome, the subsequent chapters on organization of genetic material, karyotype evolution, structural and numerical variations in chromosomes, B-chromosomes and chromosomal aberrations provide an in-depth knowledge and easy understanding of the subject matter. A special feature of the book is the inclusion of a series of chapters on various types of chromosomal aberrations and their impact on breeding behaviour and crop improvement. The possible mechanism, their consequences and role in genetic analysis has been emphasized in these chapters. A few chapters have also been dedicated on various techniques routinely used in the laboratory by students and researchers. Each chapter ends with an extensive bibliography so that the students and researchers may find it relevant to consult more literature on the subject than a book of this size can offer. The book is intended to fulfill the needs of undergraduate and post graduate students of botany, zoology and agriculture besides, teachers and researchers engaged in the field of genetics, cytogenetics, and molecular genetics. In general the readers will find each chapter of the book informative and easy to understand.
Chromosome Aberrations
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Author : G. Obe
language : en
Publisher: S Karger Ag
Release Date : 2004-01-01
Chromosome Aberrations written by G. Obe and has been published by S Karger Ag this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-01-01 with Medical categories.
The role of chromosome aberrations in evolution and human health is well recognized. This volume brings together papers summarizing our current knowlege of the structure of interphase nuclei, chromosome structure, mechanisms of aberration formation and the practical application of this knowledge in radiobiology, biomonitoring of human populations and cancer research. Molecular cytogenetic techniques such as fluorescence in situ hybridization using whole chromosome and region specific painting DNA probes have been successfully used to identify and quantify chromosome aberrations, which is reflected in several papers of this volume. The mechanisms of chromosome aberration formation by different types of ionizing radiation are considered in detail. Furthermore, the important role of telomeres in maintaining chromosome integrity and their involvement in genomic instability are discussed. A final section is dedicated to the clinical relevance of chromosome aberrations in human hereditary diseases, e.g. Fanconi anemia or ataxia telangiectasia, and in many human cancers characterized by specific translocations or deletions. The study of chromosome aberrations is of great relevance in clinical genetics and oncology for diagnosis and disease prevention. Thus this publication is recommended reading for cytogeneticists, radiobiologists, oncologists, and post-graduate students of genetics and medicine.
The Causes And Consequences Of Chromosomal Aberrations
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Author : Ilan R. Kirsch
language : en
Publisher: CRC Press
Release Date : 1992-12-21
The Causes And Consequences Of Chromosomal Aberrations written by Ilan R. Kirsch and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-12-21 with Science categories.
The Causes and Consequences of Chromosomal Aberrations explores one of the most dramatic examples of genomic instability-chromosomal aberrations. It describes some of the more recent techniques used to map genes within the human genome, study chromosomal aberrations at the cellular level, and define the organization of the interphase nucleus. General overviews are provided to build a conceptual framework for understanding the generality and specificity of chromosomal aberrations. The Causes and Consequences of Chromosomal Aberrations also explores the role of recombinases and topoisomerases in the development of chromosomal aberrations. It contains studies of chromosomal aberrations, which offer separate instructive treatises on specific malignancies. The Causes and Consequences of Chromosomal Aberrations is useful to medical and graduate students, physicians, molecular biologists, and cytogeneticists. It will benefit anyone interested in the concepts, contributions, and development in the field of molecular cytogenetics.
Human Chromosomes
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Author : Eeva Therman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Human Chromosomes written by Eeva Therman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book provides an introduction to human cytogenetics. It is also suitable for use as a text in a general cytogenetics course, since the basic features of chromosome structure and behavior are shared by all eukar yotes. Because my own background includes plant and animal cytoge netics, many of the examples are taken from organisms other than man. Since the book is written from a cytogeneticist's point of view, human syndromes are described only as illustrations of the effects of abnormal chromosome constitutions on the phenotype. The selection of the phe nomena to be discussed and of the photographs to illustrate them is, in many cases, subjective and arbitrary and is naturally influenced by my interests and the work done in our laboratory. The approach to citations is the exact opposite of that usually used in scientific papers. Whenever possible, the latest and/or most comprehen sive review has been cited, instead of the original publication. Thus the reader is encouraged to delve deeper into any question of interest to him or her. I am greatly indebted to many colleagues for suggestions and criticism. However, my special thanks are due to Dr. JAMES F. CROW, Dr. TRAUTE M. SCHROEDER, and Dr. CARTER DENNISTON for their courage in reading the entire manuscript. I wish to express my gratitude also to the cytogeneticists and editors who have generously permitted the use of published and unpublished photographs.
Some Aspects Of Chromosome Structure And Function
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Author : R.C. Sobti
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Some Aspects Of Chromosome Structure And Function written by R.C. Sobti and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
It was at the end of the 19th century that a Swiss biologist, Karl Nageli first proposed the existence of hereditary organelles that carried information from parent to offspring. Ensuing decades experienced vigorous studies that led to the development of discovery that chromosomes are indeed the carriers of genetic information. Subsequent studies, especially by Morgan and Bridges, established unequivocally the chromosome theory of inheritance. Today, the structure of chromosome is well established. At the physical level, eukaryotic chromosomes are composed of a single, linear, double helix of DNA. The elementary helical structure involves nucleosomes, comprised of histones around which the DNA is wrapped. A hierarchy of higher order of chromosomal architecture may possibly be responsible for the regulation of gene helical structures expression. The localized condensations of DNA constitute chromomeres. Uncoiled structures sometimes extending from chromomeres, which form loops, is the result of discontinuities in the regular coiling of the DNA in the chromosome.
Catalogue Of Unbalanced Chromosome Aberrations In Man
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Author : Albert Schinzel
language : en
Publisher: Walter de Gruyter GmbH & Co KG
Release Date : 2020-10-26
Catalogue Of Unbalanced Chromosome Aberrations In Man written by Albert Schinzel and has been published by Walter de Gruyter GmbH & Co KG this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-10-26 with Medical categories.
No detailed description available for "Catalogue of Unbalanced Chromosome Aberrations in Man".
Human Chromosomes
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Author : Eeva Therman
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Human Chromosomes written by Eeva Therman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book, like the two previous editions, was written as an introduction to human cytogenetics, but it could also be used as a text for a general cytogenetics course, since chromosome structure and behavior are similar in all eukaryotes. Many examples in this book are from organisms other than humans, reflecting our combined backgrounds of molecular and bacterial genetics, and plant and animal cytogenetics. In the rapidly expanding field of human cytogenetics, certain subjects, for instance clinical and cancer cytogenetics, are now covered in recently published, thousand-page volumes. In this book, such subjects are presented only in outline. The enormous growth of information has also made the choice of topics and of examples to illustrate them even more arbitrary and subjective than in the previous editions. Apart from a few pages here and there, the text has been rewritten. Major parts, especially those on molecular matters, have been added. This book would not exist without the dedicated participation of Mrs. Barbara Susman. She has been involved in the project from the planning stages to the final proofreading. She has done the extensive literature research, designed most of the tables and illustrations, and edited and typed the text. For discussions and suggestions we are indebted to many colleagues. We wish especially to mention Drs. Lassi Alvesalo, Evelyn M. Kuhn, and Renata Laxova, who have critically read selected parts of the book, and Dr. Carter Denniston, who has read the whole text.
Chromosomal Aberrations
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Author : Günter Obe
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Chromosomal Aberrations written by Günter Obe and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Chromosomale Mutationen sind eine der m|glichen Ursachen f}r Ver{nderungen der Erbinformation. Neben grunds{tzlichen As- pekten, wie Reparaturmechanismen der Zelle oder Ursachen von Chromosomenver{nderungen, werden angewandte Aspekte, z.B. Chromosomen als Testindikatoren der Toxizit{t, behandelt.