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Cilia


Cilia
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Primary Cilia


Primary Cilia
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-11-30

Primary Cilia written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-30 with Science categories.


In recent years, the role of cilia in the study of health, development and disease has been increasingly clear, and new discoveries have made this an exciting and important field of research. This comprehensive volume, a complement to the new three-volume treatment of cilia and flagella by King and Pazour, presents easy-to-follow protocols and detailed background information for researchers working with cilia and flagella. *Covers protocols for primary cilia across several systems and species * Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time * Relevant to clinicians and scientists working in a wide range of fields



Cilia From Mechanisms To Disease Part A


Cilia From Mechanisms To Disease Part A
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Author :
language : en
Publisher: Elsevier
Release Date : 2023-03-24

Cilia From Mechanisms To Disease Part A written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-24 with Science categories.


Cilia: From Mechanisms to Disease, Part A, Volume 175 in the Methods in Cell Biology series, offers a range of techniques and protocols that can be used to study aspects of this interesting cellular organelle both in vitro and in vivo. Sections in this new release include Protocols to induce and study ciliogenesis, Flow Cytometry-Based Approach for the study of primary Cilia, Microscopic observation of human airway ciliary movement using wheat germ agglutinin, Time-lapse imaging of primary cilia behavior with physiological expression of fluorescent ciliary proteins, Evaluation of ciliary-GPCR dynamics using a validated organotypic brain slice culture method, and much more. Other sections cover Studying the morphology, composition and function of the photoreceptor primary cilium in zebrafish, Visualizing Multiciliated Cells in the Zebrafish, Isolation of Ciliary Ectosomes and Analysis of Peptide-mediated Chemotaxis in Chlamydomonas, Using Paramecium as a Model for Ciliopathies, Using organoids to study cilia, Using in vivo cerebellar electroporation to study neuronal cell proliferation and differentiation in a Joubert syndrome mouse model, and more. Offers a detailed overview of the protocols used to study cilia structure and various aspects of ciliary function Provides an approach to the study of some diseases related to ciliary dysfunction, also known as ciliopathies Written in an accessible style by renowned experts in the field



The Biology Of Cilia And Flagella


The Biology Of Cilia And Flagella
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Author : M. A. Sleigh
language : en
Publisher: Elsevier
Release Date : 2016-01-11

The Biology Of Cilia And Flagella written by M. A. Sleigh and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-01-11 with Science categories.


The Biology of Cilia and Flagella reviews advances in the study of cilia and flagella since 1928. This book focuses on four main topics—structure of cilia, factors that affect ciliary activity, movement of cilia and flagella, and coordination of beat of cilia. In these topics, this compilation specifically discusses the intracellular structures associated with ciliary bases; viscosity of the medium and ciliary activity, and energy relationships of cilia and flagella. The compounding of synchronously beating cilia, variations in shaft structure, and control of ciliary activity by the organism are also elaborated. This text likewise covers the determination of the rate of beat of cilia and root-fiber systems and coordination of ciliary beat. This publication is suitable for biologists and clinicians of other disciplines researching on the structure and physiology of cilia and flagella.



Cilia Ciliated Epithelium And Ciliary Activity


Cilia Ciliated Epithelium And Ciliary Activity
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Author : José A. Rivera
language : en
Publisher: Elsevier
Release Date : 2013-10-22

Cilia Ciliated Epithelium And Ciliary Activity written by José A. Rivera and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.


Cilia, Ciliated Epithelium, and Ciliary Activity reviews the state of knowledge of the activity of cilia and of the role these structures play in maintaining the normal physiology of the body, especially in the respiratory and genital systems. It relates the diversity of manifestations shown by cilia and ciliated epithelium in health and disease, and the effect of the physicochemical agents studied which influence the life and death of these structures. The volume is organized into five sections. Section A provides a general discussion on the history of studies on the ciliated epithelium; the distribution and morphology of cilia; development, regeneration and transformation of ciliated cells; and culture of cilia and ciliated epithelium. Section B deals with ciliary activity while Section C examines the effects of physical and chemical agents on cilia. Section D takes up the function of cilia. Section E contains a list of references of the literature on these topics from the historical beginning of studies in the field to the time of writing. This volume is intended to be a ready-made reference source for workers in the fields of biological sciences and medicine.



Cilia


Cilia
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Author : Paraskevi Goggolidou
language : en
Publisher: CRC Press
Release Date : 2018-02-28

Cilia written by Paraskevi Goggolidou and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-28 with Science categories.


The scope of the book is to highlight the diverse roles of cilia in human development and disease. Almost all cell types form cilia and although they were first detected about 200 years ago, their significance was unclear. In the past ten years, it has become obvious that cilia have got sensory functions, as well as roles in motility and their mis-formation or the deregulation of the signaling pathways they control has been associated with defective development and human disease. Although research has concentrated on the role of the cilium in each organ, no effort has been made so far to bring all this information together and relate it to the various human diseases. This book aims to gather all the expertise that has been acquired on primary cilia and translate it into a medical and research context that will be of interest to postgraduate students, researchers, medics and scientists.



Cilia And Nervous System Development And Function


Cilia And Nervous System Development And Function
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Author : Kerry L. Tucker
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-19

Cilia And Nervous System Development And Function written by Kerry L. Tucker and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-19 with Medical categories.


Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and morphogenesis. Both primary and motile cilia also play crucial roles in the function of the nervous system, including the primary processing of sensory information, the control of body mass, and higher functions such as behavior and cognition, serving as "antennae" for neurons to sense and process their environment. In this book we describe the structure and function of cilia and the various tissues throughout the brain and spinal cord that are dependent upon cilia for their proper development and function.



Cilia


Cilia
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Author : Vito Mennella
language : en
Publisher: Springer Nature
Release Date : 2023-11-20

Cilia written by Vito Mennella and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-11-20 with Science categories.


This volume covers the latest advancements in the study of ciliary complexity. Protocols cover genomic, proteomic, imaging, and functional analysis of different ciliated tissues and their wide applicability in cilia biology. Chapters in this book primarily focus on methods to study multiciliated cells, and discuss topics such as SARS-CoV-2 infections of human primary nasal multiciliated epithelial cells; expansion microscopy of ciliary proteins; live-imaging centriole amplification in mouse brain multiciliated cells; biophysical properties of cilia motility; and mucociliary transport device construction. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Cilia: Methods and Protocols is a valuable resource for researchers who are interested in learning more about this developing field.



Cilia Structure And Motility


Cilia Structure And Motility
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-11-27

Cilia Structure And Motility written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-27 with Science categories.


Along with its companion volume on intraflagellar transport, this book provides researchers with a comprehensive and up-to-date source of methods for the analysis cilia and flagella, focusing primarily on approaches that have been devised or significantly extended since the last volume of Methods in Cell Biology on this topic (volume 47, 1995). Edited by Stephen M. King and Gregory J. Pazour, the newest installment of this highly acclaimed serial will serve as an essential addition to the study of cilia and flagella. Covers protocols for cilia and flagella across systems and species Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time Relevant to clinicians interested in respiratory disease, male infertility, and other syndromes who need to learn biochemical, molecular, and genetic approaches to studying cilia, flagella, and related structures



Cilia Part A


Cilia Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2013-03-12

Cilia Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-12 with Science categories.


This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers cilia Contains chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium



Cilia And Flagella


Cilia And Flagella
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Author :
language : en
Publisher: Academic Press
Release Date : 1995-08-31

Cilia And Flagella written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995-08-31 with Science categories.


Cilia and Flagella presents protocols accessible to all individuals working with eukaryotic cilia and flagella. These recipes delineate laboratory methods and reagents, as well as critical steps and pitfalls of the procedures. The volume covers the roles of cilia and flagella in cell assembly and motility, the cell cycle, cell-cell recognition and other sensory functions, as well as human diseases and disorders. Students, researchers, professors, and clinicians should find the book's combination of "classic" and innovative techniques essential to the study of cilia and flagella. Key Features * A complete guide containing more than 80 concise technical chapters friendly to both the novice and experienced researcher * Covers protocols for cilia and flagella across systems and species from Chlamydomonas and Euglena to mammals * Both classic and state-of-the-art methods readily adaptable across model systems, and designed to last the test of time, including microscopy, electrophoresis, and PCR * Relevant to clinicians interested in respiratory disease, male infertility, and other syndromes, who need to learn biochemical, molecular, and genetic approaches to studying cilia, flagella, and related structures