Circumventricular Organs And Brain Fluid Environment
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Circumventricular Organs And Brain Fluid Environment
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Author :
language : en
Publisher: Elsevier
Release Date : 1992-08-04
Circumventricular Organs And Brain Fluid Environment written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992-08-04 with Medical categories.
Circumventricular Organs and Brain Fluid Environment
Circumventricular Organs And Brain Fluid Environment
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Author : Armin Ermisch
language : en
Publisher:
Release Date : 1992
Circumventricular Organs And Brain Fluid Environment written by Armin Ermisch and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Blood-brain barrier categories.
Frontiers In Cerebral Vascular Biology
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Author : Lester R. Drewes
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Frontiers In Cerebral Vascular Biology written by Lester R. Drewes and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
During the past three decades, the cerebral vasculature and its role in blood-brain transport has been an increasingly active area of investigation and learning, particularly from an anatomical and physiological point of view. However, much less is known at the molecular and cellular level about the blood-brain barrier especially regarding the macromolecules responsible for transport, the roles played by vascular wall components (endothelial cell, pericyte, smooth muscle, basement membrane), and the mechanisms regulating brain vascular-specific protein expression and their molecular alterations during development and disease. Fundamental questions still unanswered include: What are the molecular constituents of brain endothelial cell tight junctions? What are the membrane proteins responsible for transport of specific substrates? What are the molecular signals that cause glucose transporter gene expression to be 20 to 100 times greater in brain endothelial cells in vivo than in vitro? What roles do pericytes, smooth muscle cells and basement membrane have in establishing or maintaining blood-brain transport characteristics? Are brain vascular transport systems responsible for edema following injury? Are transporter systems regulated via receptor-mediated events? Do hormones or neuromodulators regulate transporter expression? What is the molecular mechanism by which plasma proteins enter the extravascular space? Are transporters asymmetrically distributed between the luminal and abluminal endothelial cell membranes? Can prodrugs or pharmacologic agents be designed as substrate analogs and be delivered to the central nervous system via existing transporters or receptors? Can new and beneficial transporters be introduced into the brain vasculature?
Gene Expression In The Central Nervous System
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Author : Albert C. H. Yu
language : en
Publisher: Elsevier
Release Date : 1995
Gene Expression In The Central Nervous System written by Albert C. H. Yu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1995 with Juvenile Nonfiction categories.
Gene expression is an active ongoing process that maintains a functional CNS, as proteins are being made on a continual basis. Processes such as learning and memory, nerve cell repair and regeneration and its response to stress are critically dependent on gene expression. This volume highlights the role of gene expression in normal CNS function, and presents many research methods at the cutting edge of neuroscience, which will provide insight into therapeutic approaches through which the control of gene expression may be used in the treatment of many nervous system diseases.
The Self Organizing Brain From Growth Cones To Functional Networks
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Author : M.A. Corner
language : en
Publisher: Elsevier
Release Date : 1994-10-11
The Self Organizing Brain From Growth Cones To Functional Networks written by M.A. Corner and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994-10-11 with Psychology categories.
This book concentrates on the organizational level of neurons and neuronal networks under the unifying theme "The Self-Organizing Brain - From Growth Cones to Functional Networks". Such a theme is attractive because it incorporates all phases in the emergence of complexity and (adaptive) organization, as well as involving processes that remain operative in the mature state.The order of the sections follows successive levels of organization from neuronal growth cones, neurite formation, neuronal morphology and signal processing to network development, network dynamics and, finally, to the formation of functional circuits.
The Visually Responsive Neuron
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Author : T.P. Hicks
language : en
Publisher: Elsevier
Release Date : 1993-03-18
The Visually Responsive Neuron written by T.P. Hicks and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-03-18 with Medical categories.
This timely new volume presents broad-based and wide-ranging contributions on all aspects of vision. The material is grouped for presentation in a logical fashion in five main themes: peripheral processing; sensory integration in superior colliculus; organization of visual projections; development and plasticity; and neuronal encoding and visually guided behavior.The material spans from molecules to cognition, including overt behavior, and synaptic and membrane levels of analysis. The species studied also range over diverse phyla, while contributors too form a diverse group representing Europe, North America, and Asia. The Visually Responsive Neuron is an exciting and informative addition to the well known Progress in Brain Research series.
Neurobiology Of Ischemic Brain Damage
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Author : K. Kogure
language : en
Publisher: Elsevier
Release Date : 1993-05-10
Neurobiology Of Ischemic Brain Damage written by K. Kogure and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-05-10 with Medical categories.
In the eight years since the publication of Volume 63 of Progress in Brain Research, on this subject, developments in the research field have been very fast. For example, receptor physiology and pharmacology is now an intensively studied field, and the excitotoxic hypothesis of cell death is commonly accepted. Furthermore, it is recognized that ischemia and other insults give rise to a sustained depression of overall protein synthesis, yet lead to the expression of dormant genes and to synthesis of new proteins.In view of this development, this volume focusses on the cellular and molecular aspects of ischemic brain damage. The book will be of great value to all those interested in the pathophysiology of ischemic and traumatic brain damage.
Cytokines And The Brain
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Author :
language : en
Publisher: Elsevier
Release Date : 2008-06-18
Cytokines And The Brain written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-06-18 with Science categories.
This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer's disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment.*Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease*Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease*Includes novel approaches to the treatment of CNS disorders based on new experimental data*Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment
Interleukin 1 In The Brain
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Author : Nancy J. Rothwell
language : en
Publisher: Elsevier
Release Date : 2013-10-22
Interleukin 1 In The Brain written by Nancy J. Rothwell and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-22 with Science categories.
Interest in interleukin-1 (IL-1) has increased dramatically over the last decade, but has been largely restricted to immunologists, cell biologists and those studying inflammation and cancer. However, it has recently been recognized that the brain directly controls or modulates many aspects of immune function, while molecules classically associated with the immune system, such as interleukin-1, are synthesised within the brain and act directly on the central nervous system to modify local and systemic functions. Thus, this topic is relatively new to neurobiologists, and this book is the first comprehensive description of current knowledge on interleukin-1 in the brain, including its location, synthesis and receptors, actions on behaviour, fever, metabolism, neuroendocrine function, electrical activity of the brain, nerve growth factor, and relationship to clinical indications. The book is organised into three sections. The first reviews the data available on the neural localisation of IL-1 and the nature of its central receptors. The main part of the book examines the different neural effects of IL-1 and the mechanisms which are involved in these actions, comparing IL-1 where possible to other inflammatory cytokines which also have neurotrophic effects. The final section evaluates the possible role of IL-1 in neural plasticity and neuronal degeneration.
Natural And Artificial Control Of Hearing And Balance
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Author :
language : en
Publisher: Elsevier
Release Date : 1993-09-06
Natural And Artificial Control Of Hearing And Balance written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-09-06 with Medical categories.
Natural and Artificial Control of Hearing and Balance