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Cirrhosis Hepatic Encephalopathy And Ammonium Toxicity


Cirrhosis Hepatic Encephalopathy And Ammonium Toxicity
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Cirrhosis Hepatic Encephalopathy And Ammonium Toxicity


Cirrhosis Hepatic Encephalopathy And Ammonium Toxicity
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Author : Santiago Grisolía
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-08

Cirrhosis Hepatic Encephalopathy And Ammonium Toxicity written by Santiago Grisolía and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-08 with Medical categories.


Proceedings of an international symposium held in Valencia, Spain, November 27--29, 1989



Hepatic Encephalopathy Hyperammonemia And Ammonia Toxicity


Hepatic Encephalopathy Hyperammonemia And Ammonia Toxicity
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Author : Vicente Felipo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Hepatic Encephalopathy Hyperammonemia And Ammonia Toxicity written by Vicente Felipo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This volume contains the papers presented at the International Symposium on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy", held in Valencia, Spain, January 24th-27th, 1994. Liver cirrhosis and other hepatic dysfunctions such as fulminant hepatic failure and congenital defects of urea cycle enzymes can lead to hepatic encephalopathy, coma and death. Hepatic encephalopathy is one of the main causes of death in western countries. The ability to detoxify ammonia by its incorporation into urea is diminished by impaired liver function, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. However, the molecular bases of the pathogenesis of hepatic encephalopathy and the role of hyperammonemia in this process remain unclear and several hypotheses have been proposed. To clarify the mechanisms involved in hepatic encephalopathy and hyperammonemia suitable animal models are necessary. The animal models available and the ideal features of an animal model are presented in the initial part of the book.



Cirrhosis Hyperammonemia And Hepatic Encephalopathy


Cirrhosis Hyperammonemia And Hepatic Encephalopathy
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Author : Santiago Grisolía
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Cirrhosis Hyperammonemia And Hepatic Encephalopathy written by Santiago Grisolía and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye's syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues, including brain, is also presented, as well as the effects of hyperammonemia on brain metabolism and function and on brain microtubules. The control of cerebral protein breakdown is reviewed. The classical and some recently proposed clinical treatments as well as nutritional considerations in the management of patients with liver failure are also discussed.



Advances In Cirrhosis Hyperammonemia And Hepatic Encephalopathy


Advances In Cirrhosis Hyperammonemia And Hepatic Encephalopathy
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Author : Vicente Felipo
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Advances In Cirrhosis Hyperammonemia And Hepatic Encephalopathy written by Vicente Felipo and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Proceedings of an international symposiu, held in Valencia, Spain, December 2-4, 1996



Hepatic Encephalopathy


Hepatic Encephalopathy
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Author : Kevin D. Mullen
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-05-30

Hepatic Encephalopathy written by Kevin D. Mullen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-30 with Medical categories.


Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy.



Encephalopathy And Nitrogen Metabolism In Liver Failure


Encephalopathy And Nitrogen Metabolism In Liver Failure
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Author : E. Anthony Jones
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Encephalopathy And Nitrogen Metabolism In Liver Failure written by E. Anthony Jones and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Encephalopathy and Nitrogen Metabolism in Liver Failure contains research reports and state-of-the-art reviews that were presented at the 11th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism in relation to liver disease, that was held in Amsterdam, The Netherlands from 30 May to 1 June, 2002. Themes covered include the metabolism of ammonia and amino acids in relation to liver disease, the assessment of hepatic encephalopathy (HE), minimal HE, animal models of HE, neuropsychiatric dysfunction in patients with chronic liver disease, the pathogenesis of HE, the astrocyte in liver disease, acute liver failure and cerebral edema, treatment of HE and artificial liver support systems. This volume provides an indispensable source of important new research findings and ideas for clinicians and biomedical scientists working in the field of HE and nitrogen metabolism in relation to liver disease.



Hepatic Encephalopathy


Hepatic Encephalopathy
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Author : Roger F. Butterworth
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Hepatic Encephalopathy written by Roger F. Butterworth and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.




Hepatic Encephalopathy In Chronic Liver Failure


Hepatic Encephalopathy In Chronic Liver Failure
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Author : Livio Capocaccia
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Hepatic Encephalopathy In Chronic Liver Failure written by Livio Capocaccia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The meeting which took place in Rome on November 19th and 20th of 1982 is easily the best meeting on hepatic coma that I have ever attended, and I have attended many. It was an exceedingly we- planned meeting with prolonged opportunity for discussion, and there was genuine interplay and exchange of ideas (not the usual picture of a rushed meeting with investigators presenting their own point of view and talking past each other without a meaningful ex change) which took place in Rome. My co-editors and I hope that the published transcript, which of course can only reflect what transpired in Rome on those two days, does justice to a very intellectually exciting and gratifying ex change of ideas. L. Capocaccia, J. E. Fischer and F. Rossi-Fanelli v CONTENTS Introduction 1 SECTION 1: PATHOGENETIC PROBLEMS IN HEPATIC ENCEPHALOPATHY Ammonia: The old and the new • • . • • • . • . • • • . • . • 5 L. Zieve Role of synergism in the pathogenesis of hepatic encephalopathy • • • • . • • . . . . • 15 L. Zieve y-Aminobutyric acid receptors in experimental hepatic encephalopathy •. •. • • 25 M. L. Zeneroli, ~. Baraldi,and E. Ventura A possible role for excitatory neurotoxic amino acids in the pathogenesis of hepatic en 41 cephalopathy • • • • • • • • • • • • • • • F. Moroni, G. Lombardi, G. Moneti, D. Pellegrini and C.



Hepatic Encephalopathy


Hepatic Encephalopathy
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Author : Frederick Steigmann
language : en
Publisher:
Release Date : 1971

Hepatic Encephalopathy written by Frederick Steigmann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1971 with Medical categories.




Advances In Hepatic Encephalopathy And Urea Cycle Diseases


Advances In Hepatic Encephalopathy And Urea Cycle Diseases
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Author : Gunter Kleinberger
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1984

Advances In Hepatic Encephalopathy And Urea Cycle Diseases written by Gunter Kleinberger and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1984 with Amino acid metabolism categories.