Clinical Trials In Neurology
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Clinical Trials In Neurology
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Author : Roberto J. Guiloff
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-14
Clinical Trials In Neurology written by Roberto J. Guiloff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-14 with Medical categories.
Clinical Trials in Neurology comprehensively tackles the methodology and design of clinical trials in neurological disease. A general section deals with the ethical aspects, drug development and regulatory requirements, basic trial designs and the statistics used. A diseases section tackles specific aspects of disorders, focusing on the relevant ethical issues, outcome variables and experience with large multicentre trials.
Controlled Clinical Trials In Neurological Disease
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Author : Roger J. Porter
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Controlled Clinical Trials In Neurological Disease written by Roger J. Porter and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The evaluation of the efficacy and safety of a clinical tool, be it a diagnostic technique, a preventive methodology, or a therapeutic intervention, is an im portant responsibility of physicians. The history of medicine is characterized by the authoritarianisms of teachers and of organizations giving way to the clinical experience of physicians; authoritarian dictum was replaced by case report and then by case series. As physicians learned to substitute the analysis of data for the inconsistencies of dictums and anecdotes, the problems of the case series as an investigative tool became more evident: patient selection criteria, measurements of outcome, significance of results, and extrapolation of conclusions to the community of patients. In response to these issues, the methodology of the controlled clinical trial has evolved and with it the instru ments of study design and of biostatistics as aids to study design and data analysis. The medical - surgical armamentarium has evolved from being dependent solely upon the observations and conclusions of a skilled clinician to being constructed upon the systematic collection and evaluation of data by a team of skilled clinicians and their statistical colleagues: this is the controlled clinical trial. During the past two decades, the evaluation of clinical approaches to pre vention and therapy has become particularly important to clinicians concerned with nervous system dysfunction. There has been and continues to be an explosion of information from the basic neurosciences and from the applica tion of biotechnology to the nervous system.
Clinical Trials In Neurology
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Author : Bernard Ravina
language : en
Publisher: Cambridge University Press
Release Date : 2012-04-12
Clinical Trials In Neurology written by Bernard Ravina and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-04-12 with Medical categories.
Comprehensive book that suggests ways to improve the efficiency of clinical trials and the development of interventions in the neurosciences.
The Right Therapy For Neurological Disorders
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Author : E. Beghi
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2016-07-26
The Right Therapy For Neurological Disorders written by E. Beghi and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-26 with Medical categories.
Most neurological disorders are chronic and aging-related. With the increase of life expectancy their incidence and prevalence will grow in the decades to come, which in turn will increase the load on medical and social systems worldwide. There is thus a desperate need for successful preventive and therapeutic measures based on randomized clinical trials (RTCs) conducted by independent organizations. This book provides a compendium relating most of the principles of reliable RTCs to specific neurological diseases. Contributed by specialized neurologists, the articles touch on important aspects of RCTs with a clear critical approach, highlighting their limitations as well as giving recommendations for their planning and conducting to address the variable genotypic and phenotypic aspects of neurological conditions. Consideration is also given to combining the clinical impact of the study results with patients’ values and the interests of pharmaceutical companies. Neurologists involved in clinical trials will certainly benefit from this book, which should become a basic text for all neurological courses dealing with evidence-based neurology.
Clinical Trials In Neurology
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Author : Bernard Ravina
language : en
Publisher:
Release Date : 2012
Clinical Trials In Neurology written by Bernard Ravina and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Clinical trials categories.
Comprehensive book that suggests ways to improve the efficiency of clinical trials and the development of interventions in the neurosciences.
Methods In Clinical Trials In Neurology
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Author : Rudy Capildeo
language : en
Publisher: Springer
Release Date : 1988-06-18
Methods In Clinical Trials In Neurology written by Rudy Capildeo and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-06-18 with Medical categories.
50 Studies Every Neurologist Should Know
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Author : David Y. Hwang
language : en
Publisher: Oxford University Press
Release Date : 2016
50 Studies Every Neurologist Should Know written by David Y. Hwang and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with Medical categories.
'50 Studies Every Neurologist Should Know' presents summaries and analyses of clinical trials that have shaped the current practice of neurology. Every subspecialty is covered, with special emphasis on neurocritical care and vascular neurology.
Methods In Clinical Trials In Neurology
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Author : Rudy Capildeo
language : en
Publisher: Grove's Dictionaries
Release Date : 1988-01-01
Methods In Clinical Trials In Neurology written by Rudy Capildeo and has been published by Grove's Dictionaries this book supported file pdf, txt, epub, kindle and other format this book has been release on 1988-01-01 with Medical categories.
Clinical Trials In The Neurosciences
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Author : Katherine M. Woodbury-Harris
language : en
Publisher:
Release Date : 2009
Clinical Trials In The Neurosciences written by Katherine M. Woodbury-Harris and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Clinical Trials as Topic categories.
A properly designed and executed clinical trial that addresses an import question and delivers a definitive result can change the practice of medicine worldwide. This book encompasses a bench-to-bedside approach and serves as an excellent guidance for translating preclinical studies to early phase I/II and phase III trials. In the first part, the book covers preclinical science with respect to animal models of various neurological diseases, FDA requirements for preclinical studies, translation of animal to patient studies and scaling up from animal to human studies. In the second part, the design of phase I/II trials and the use of biomarkers as surrogate endpoints are discussed. With regard to phase III trials, FDA and European requirements, specific design issues, relevant clinical endpoints as well as data management and quality are examined. Topics specific to multicenter trials, such as design, recruitment of special populations, monitoring, ethical and consent issues are also covered. Finally, genetics, gene therapy, imaging and surgical devices are reviewed. This publication is highly recommended to clinician researchers, such as neurologists, neurosurgeons, pediatric neurologists and neonatologists, who want to design and conduct clinical trials in the neuroscience, but also to nurses, research coordinators and clinical pharmacologists.
Recent Studies In Clinical Neurology
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Author : Samuel Armstrong
language : en
Publisher: Murphy & Moore Publishing
Release Date : 2021-11-16
Recent Studies In Clinical Neurology written by Samuel Armstrong and has been published by Murphy & Moore Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-11-16 with Medical categories.
The branch of science that is concerned with the study of disorders of the nervous system is known as neurology. It deals with the diagnosis and treatment of all the conditions and diseases of peripheral and central nervous system as well as their blood vessels, coverings and all effector tissues such as muscles. Neurology is a non-surgical specialty and its specialists can be involved in clinical trials, clinical research and translational research. Symptoms that may require medical attention within this field are confusion, dizziness, change in sensation, muscle weakness and coordination problems. Patients with multiple sclerosis, stroke, neuromuscular disorders, seizure disorders, infections of the nervous system such as encephalitis or brain abscesses, etc. are also treated within this field. The various sub-fields of neurology and their clinical aspects are glanced at in this book. It provides significant information of this discipline to help develop a good understanding. Students, researchers, experts and all associated with neurology will benefit alike from this book.