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Clinical Trials In Rheumatology


Clinical Trials In Rheumatology
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Clinical Trials In Rheumatoid Arthritis And Osteoarthritis


Clinical Trials In Rheumatoid Arthritis And Osteoarthritis
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Author : David M. Reid
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-20

Clinical Trials In Rheumatoid Arthritis And Osteoarthritis written by David M. Reid and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-20 with Medical categories.


Designed to be a practical handbook on clinical trial management in these key therapeutic areas, 'Clinical Trials in Rheumatoid Arthritis and Osteoarthritis' is aimed at principal investigators pharmaceutical physicians and other pharmaceutical staff involved in the design, conduct and monitoring of these increasingly complex diseases. In the last several years a new classes of biologic agents have emerged and changed the treatment paradigm for patients, not only with classically defined rheumatoid arthritis, but also with other related diseases such as ankylosing spondylitis and psoriatic arthritis. Furthermore, osteoarthritis is a major disease state that is often treated by the rheumatologist, but is one where patient management programs are currently limited with a need for new therapeutic approaches. In both inflammatory and non-inflammatory arthritic conditions, clinical trials have become both large and complex due to the nature of the diseases, with ever-challenging new surrogate end-points being employed. Topics covered in this title will therefore include study design, clinical endpoints, technical issues, data collection, use of centralized medical image reading facilities and biochemical marker laboratories, as well as data analysis and future therapies. This book takes the user through the process step-by-step from start to finish, also providing a background on the regulatory guidelines, ethical implications, endpoints, and current therapies.



Clinical Trials In Rheumatology


Clinical Trials In Rheumatology
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Author : Ruediger Mueller
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-01

Clinical Trials In Rheumatology written by Ruediger Mueller and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-01 with Medical categories.


A huge number of therapeutic studies has been published in rheumatology and clinical immunology. This number grows substantially by the year. As such, it becomes increasingly difficult to keep track of this multitude of studies and the ensuing therapeutic trends. Further to this, a particular study can be referred to in a variety of ways, either as a shortened version of the title or an acronym, adding to the confusion. The book Clinical Trials in Rheumatology provides a summary of the important studies in the field for easy reference. Every study is shown with name, acronym (if in existence), authors, complete citation, study design, results, and summary. An acronym finder is supplied at the beginning of the book. This book is a valuable reference tool for rheumatologists and other clinical specialties, as well as for research scientists interested in immunomodulatory and selected other drug therapies in rheumatologic diseases.



Understanding Evidence Based Rheumatology


Understanding Evidence Based Rheumatology
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Author : Hasan Yazici
language : en
Publisher: Springer
Release Date : 2014-10-29

Understanding Evidence Based Rheumatology written by Hasan Yazici and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-29 with Medical categories.


It is imperative that health professionals caring for patients with rheumatic diseases understand how to correctly interpret evidence in their field, taking into account the merits and shortcomings of available data. Understanding Evidence-Based Rheumatology offers a practical assessment of criteria, drugs, trials, and registries and provides useful tools for successfully interpreting this data. The book introduces readers to basic analysis of trial design, statistics and application of data through no-nonsense, easy-to-follow insights. Using numerous examples, chapters outline the difficulties physicians encounter when measuring disease activity in rheumatology and offer strategies for systematically approaching these situations. Ethical issues in study design and reporting are examined and the book closes with a summary of future directions for scientific and clinical studies in rheumatology. Understanding Evidence-Based Rheumatology is an invaluable resource for trainees, clinicians and scientists, preparing them with the necessary tools to correctly gather evidence and shed light on the difficult practice of rheumatology.



Best Practices And Challenges To The Practice Of Rheumatology An Issue Of Rheumatic Disease Clinics Of North America


Best Practices And Challenges To The Practice Of Rheumatology An Issue Of Rheumatic Disease Clinics Of North America
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Author : Daniel J. Wallace
language : en
Publisher: Elsevier Health Sciences
Release Date : 2018-11-21

Best Practices And Challenges To The Practice Of Rheumatology An Issue Of Rheumatic Disease Clinics Of North America written by Daniel J. Wallace and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-11-21 with Medical categories.


Guest edited by Drs. Daniel J. Wallace and R. Swamy Venuturupalli, this issue of Rheumatic Disease Clinics will cover several key areas of interest related to Best Practices and Challenges to the Practice of Rheumatology. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman of Cedars-Sinai. Articles in this issue include, but are not limited to: The Economics of Rheumatology Practice in the United States, Manpower trends in rheumatology, Challenges to practicing rheumatology in an academic center, Challenges in practicing rheumatology in a government setting, Challenges to practicing rheumatology in a small private practice setting, Challenges to working in a large multispecialty organization, Challenges to practicing pediatric rheumatology, Clinical trials in rheumatology, Challenges in having an infusion center, Implementing treatment to target in the clinic, Future directions: implementing new technologies in clinical practice, Possible Challenges in Optimizing Medical Education for Rheumatologists, and the challenges of approaching and managing gout.



Modern Therapeutics In Rheumatic Diseases


Modern Therapeutics In Rheumatic Diseases
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Author : George C. Tsokos
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-11-08

Modern Therapeutics In Rheumatic Diseases written by George C. Tsokos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-08 with Medical categories.


Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.



Landmark Papers In Rheumatology


Landmark Papers In Rheumatology
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Author : Scott Watts
language : en
Publisher: Academic
Release Date : 2015

Landmark Papers In Rheumatology written by Scott Watts and has been published by Academic this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015 with Medical categories.


There have been major developments in our understanding of the causes of rheumatic disease and in their treatment during the last half-century. This book provides a detailed review of the seminal papers that have paved the way for breakthroughs in the clinical management of the entire spectrum of rheumatic disease.



Clinical Trials In The Rheumatic Diseases


Clinical Trials In The Rheumatic Diseases
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Author :
language : en
Publisher:
Release Date : 1983

Clinical Trials In The Rheumatic Diseases written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1983 with Rheumatism categories.




Clinical Trials In The Rheumatic Diseases


Clinical Trials In The Rheumatic Diseases
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Author : David Rosenbloom
language : en
Publisher: Praeger Publishers
Release Date : 1985-03-01

Clinical Trials In The Rheumatic Diseases written by David Rosenbloom and has been published by Praeger Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 1985-03-01 with Medical categories.


This book reviews the design, measurement, and analytic components of randomized clinical trials conducted in the rheumatic diseases and evaluates the studies on which decisions are based for treating patients. The underlying evidence for effective drug therapies is presented along with insight into the following areas: clarity of reportage of clinical trials; identification of potential sources of error and their effect on efficiency and quality of future trials. The chapters are organized according to disease and structured so as to provide basic information, methodologic considerations, description of clinical trials, and recommendations for special consideration in future trials.



Drug Safety Managing Innovation In Rheumatology An Issue Of Rheumatic Disease Clinics


Drug Safety Managing Innovation In Rheumatology An Issue Of Rheumatic Disease Clinics
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Author : Jack Cush
language : en
Publisher: Elsevier Health Sciences
Release Date : 2012-11-15

Drug Safety Managing Innovation In Rheumatology An Issue Of Rheumatic Disease Clinics written by Jack Cush and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-15 with Medical categories.


Edited by Drs. Jack Cush and Kathryn Dao, this issue of Rheumatic Disease Clinics of North America addresses one of the most significant issues facing the rheumatologist today––drug safety in a changing world where rheumatoid arthritis (RA) severity is less, patients are being identified and treated at a very early stage, and prevention is on the horizon. Topics covered include: communicating the risk of side effects, urate-lowering therapies, biphosphonates, biologics, malignancy risks, and administering therapies to patients with co-morbidities.



The Arthritis Breakthrough


The Arthritis Breakthrough
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Author : Henry Scammell
language : en
Publisher: M Evans & Company
Release Date : 1993-01

The Arthritis Breakthrough written by Henry Scammell and has been published by M Evans & Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-01 with Health & Fitness categories.


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