Modern Therapeutics In Rheumatic Diseases
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Modern Therapeutics In Rheumatic Diseases
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Author : George C. Tsokos
language : en
Publisher: Springer Science & Business Media
Release Date : 2001-11-08
Modern Therapeutics In Rheumatic Diseases written by George C. Tsokos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001-11-08 with Medical categories.
Leading clinicians and clinical researchers discuss in practical detail the newest treatments used in rheumatic diseases, emphasizing-without neglecting current standard treatments-those experimental therapies now undergoing clinical trials and poised for early introduction into the rheumatology armamentarium. The diseases and therapeutic regimes examined here range from rheumatoid arthritis and its treatment by gene therapy, to osteoarthritis and systemic autoimune diseases. Each chapter is organized so that the busy clinician can quickly obtain all the information needed optimal patient treatment. This includes an analysis of the pathogenic mechanisms that explain the molecular basis of the newer therapeutics, reviews of animal data and the results of clinical trials, and recommendations concerning use, side effects, and precautions.
Handbook Of Biologics For Rheumatological Disorders
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Author : Neeraj Jain
language : en
Publisher: Springer Nature
Release Date : 2022-03-06
Handbook Of Biologics For Rheumatological Disorders written by Neeraj Jain and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-03-06 with Medical categories.
Biologics have revolutionized the treatment of autoimmune diseases due to their efficacy, speed of onset, and tolerability. The development of new agents and expanded use of existing agents continues to be a highly active area of investigation among rheumatic diseases, with a multitude of innovative therapeutic strategies in various stages of development. Although the story of treatments continues rapidly, therapeutic research in some conditions is hindered by the rarity of the disease, variation in phenotype, and concerns about toxicity. This fast-paced development of therapeutics,necessitates immediate evaluation of individual biologic agents and their best use in the new treatment regimens./div This book provides an inclusive approach with the existing evidence concerning effectiveness and implications on the usage of biologics in treating various rheumatologic disorders. It also covers the evidence behind the rational use of these agents in varied autoimmune diseases. This manual also offers a complete overview of the existing & futuristic biologic treatments, and draws recommendations on how to standardize the most suitable regimen for a specific patient in the context of current guidelines. The handbook of Biologics in Rheumatology serves as a present and concise compendium to the modern therapeutic developments in the field./div This book is likely to benefit clinicians, residents, fellow and other healthcare workers dealing with rheumatological disorders, and also hard-core Rheumatologists, who are looking for a quick recap of Biologics of their interest. /div
Therapeutics In Rheumatology
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Author : H. A. Bird
language : en
Publisher: Springer
Release Date : 2013-11-11
Therapeutics In Rheumatology written by H. A. Bird and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Medical categories.
This book is about the drugs used in the treatment and management of rheumatic disorders. The term 'therapeutics' used in the title is intended to mirror the relevance of drugs in the widest sense of the word. Thus, general principles underlying pharmaceutical and pharmacological study have been included together with more clinical matters concerned with applying specific rheumatic problems. The need for another work on rheumatological drugs in itself, as opposed to the different approach intended, was prompted by the ever continuing and bewildering plethora of antirheumatic drugs flooding the market at present. We believe that such a burgeoning of new preparations is welcome in an era when in general there are still no 'cures' available. Moreover, we also feel that a continued update of this rapidly advancing field is essential, not only for its own sake, but also to place it in perspective with itself and with neighbouring fields.
Contemporary Targeted Therapies In Rheumatology
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Author : Josef S. Smolen
language : en
Publisher: CRC Press
Release Date : 2007-10-18
Contemporary Targeted Therapies In Rheumatology written by Josef S. Smolen and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-10-18 with Medical categories.
Targeted therapies of rheumatic diseases have become a reality and have completely changed patient care as well as patient expectations. Initial success with therapies aimed at blocking TNF and IL-1 has stimulated the development of additional targeted approaches focused on other cytokines as well as specific cells and pathways involved in the path
New Developments In Antirheumatic Therapy
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Author : K. D. Rainsford
language : en
Publisher: Springer
Release Date : 2011-10-17
New Developments In Antirheumatic Therapy written by K. D. Rainsford and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-10-17 with Medical categories.
At present we may be at the cross-roads in the therapeutic approaches we have for the treatment of the 100 or more rheumatic conditions. This is be cause we now recognise that although some advances have been made with the development of a large range of non-steroidal and steroidal drugs during the past two decades or so, we now recognise that many, if not all, of these have rather limited effects on many of the disease processes which underlie the manifestations of the various rheumatic states. Advances in molecular bi- 010gy in the past 5-10 years have enabled these tools to be applied extensive ly for developing further our understanding of the rheumatic disease processes. In some cases these molecular tools (e. g. ,),-interferon, interleukin- 2, T-cell antibodies) have been directly employed as therapies themselves. While the outcome from trials with such agents in rheumatoid arthritis in particular has not been as would have been hoped, these results as with cy closporin A and low-dose methotrexate in the therapy of rheumatoid arth ritis have given us important indications for the approach employing what are generally described as "immunomodulators" to control this disease. But this may not be the same type of approach which is desirable for all types of rheumatic conditions. Indeed, even the way which the present range of drugs and other therapies are applied may not be the most effective and safe means of treating different types of arthritic conditions.
Modern Therapeutics
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Author : George Henry Napheys
language : en
Publisher:
Release Date : 1870
Modern Therapeutics written by George Henry Napheys and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1870 with Medicine categories.
Modern Therapeutics 2nd Ed
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Author : George Henry Napheys
language : en
Publisher:
Release Date : 1871
Modern Therapeutics 2nd Ed written by George Henry Napheys and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1871 with categories.
The Resolution Of Inflammation
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Author : Adriano Rossi
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-03-17
The Resolution Of Inflammation written by Adriano Rossi and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-03-17 with Medical categories.
This book provides readers with an up-to-date and comprehensive view on the resolution of inflammation and on new developments in this area, including pro-resolution mediators, apoptosis, macrophage clearance of apoptotic cells, possible novel drug developments.
Stem Cell Therapy For Autoimmune Disease
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Author : Richard K. Burt
language : en
Publisher: CRC Press
Release Date : 2019-11-11
Stem Cell Therapy For Autoimmune Disease written by Richard K. Burt and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-11 with Medical categories.
Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.
Treat To Target In Rheumatic Diseases Rationale And Results
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Author : Daniel Aletaha
language : en
Publisher: Elsevier Health Sciences
Release Date : 2019-10-10
Treat To Target In Rheumatic Diseases Rationale And Results written by Daniel Aletaha and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-10 with Medical categories.
Guest edited by Dr. Daniel Aletaha, this issue of Rheumatic Disease Clinics will cover “Treat to Target in Rheumatic Diseases with a focus on rationale and results. This issue is one of four selected each year by our series Consulting Editor, Dr. Michael Weisman. Articles explore diseases, including, but not limited to: History, Rheumatoid Arthritis, Psoriatic Arthritis, Spondylarthropathies, Systemic lupus erythematosus, PMR and GCA, Inflammatory Myopathies (PM/DM), Gout, and Subclinical Targets.