Clozapine In Treatment Resistant Schizophrenia


Clozapine In Treatment Resistant Schizophrenia
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Clozapine In Treatment Resistant Schizophrenia


Clozapine In Treatment Resistant Schizophrenia
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Author : Yvon Lapierre
language : en
Publisher:
Release Date : 1992

Clozapine In Treatment Resistant Schizophrenia written by Yvon Lapierre and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1992 with Antipsychotic drugs categories.




Therapy Resistant Schizophrenia


Therapy Resistant Schizophrenia
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Author : H. Elkis
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2010-07-29

Therapy Resistant Schizophrenia written by H. Elkis and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-29 with Medical categories.


The psychotic symptoms of up to 30% of schizophrenic patients do not respond adequately to treatment with antipsychotic drugs, other than clozapine. These refractory patients are generally among the most disabled of all people with schizophrenia and require special assessment and treatment. This volume presents the latest research and recommendations on the definition, causes and therapy of treatment-resistant schizophrenia (TRS). Methods for identification and optimal management of TRS are reviewed. Clozapine and other atypical antipsychotic drugs which are the primary treatment for TRS, as well as non-pharmacologic treatments such as transcranial magnetic stimulation, cognitive behavior therapy and ECT are discussed in depth. Potential causative factors and identifying features such as genetic factors, poor premorbid functioning, longer duration of untreated psychosis, and biological measures such as structural and functional brain abnormalities are also reviewed in depth in the present volume.



Treatment Response And Resistance In Schizophrenia


Treatment Response And Resistance In Schizophrenia
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Author : Oliver Howes
language : en
Publisher: Oxford University Press
Release Date : 2018-09-20

Treatment Response And Resistance In Schizophrenia written by Oliver Howes and has been published by Oxford University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-20 with Medical categories.


Treatment resistant schizophrenia (TRS) is common, affecting approximately a third of patients diagnosed. Despite the prevalence of TRS, the best approach to practical management is often unclear to clinicians and patients. Treatment Response and Resistance in Schizophrenia offers a practical, clinically focused guide to TRS and the real-world challenges faced by those impacted. Over 14 chapters this resource covers the principles and practice of TRS, from the definition, epidemiology, and clinical assessment, to the pharmacological, physical, and psychological management of treatment resistance. All chapters have been written by internationally leading experts in the field to ensure busy clinicians have high-quality, applicable content that is rooted in real clinical experiences. A chapter of case studies is included to link real-life scenarios to each of the instructive chapters, illustrating approaches to practical management and application. Part of the Oxford Psychiatry Library, this useful pocket book is an invaluable resource and quick reference for psychiatrists, psychiatry trainees, and other mental health practitioners, as well as clinical psychologists, primary care physicians, and specialist nurses.



Treatment Refractory Schizophrenia


Treatment Refractory Schizophrenia
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Author : Peter F. Buckley
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-03-18

Treatment Refractory Schizophrenia written by Peter F. Buckley and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-18 with Medical categories.


Schizophrenia is often associated with an inadequate response to pharmacological and non-pharmacological treatments. How to treat patients who have an unsatisfactory response to anti-psychotics, including clozapine - which is unequivocally the most powerful antipsychotic medication for this recalcitrant population - remains a clinical conundrum. A range of adjunctive medications have been tried with mixed results; there has also been renewed interest in the role of neuromodulatory strategies, electroconvulsive therapy, and cognitive and vocational approaches. Perhaps a bright spot for the future lies in the evolution of pharmacogenetic approaches for individualized care. In this book, leading experts from Europe, Australia and the Americas provide a timely appraisal of treatments for the most severely ill schizophrenia patients. This clinically focused book is informed by the latest research on the neurobiology and treatment of schizophrenia. It is comprehensive in scope, covering current treatment options, various add-on approaches, and a range of psychosocial treatments. The contributors are respected experts who have combined their clinical experience with cutting-edge research to provide readers with authoritative information on fundamental aspects of clinical care for schizophrenia.



Decreasing The Impact Of Treatment Resistance In Schizophrenia Identifying Novel Molecular Targets Pathways To Increase Treatment Efficacy


Decreasing The Impact Of Treatment Resistance In Schizophrenia Identifying Novel Molecular Targets Pathways To Increase Treatment Efficacy
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Author : Mirko Manchia
language : en
Publisher: Frontiers Media SA
Release Date : 2020-08-27

Decreasing The Impact Of Treatment Resistance In Schizophrenia Identifying Novel Molecular Targets Pathways To Increase Treatment Efficacy written by Mirko Manchia and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-08-27 with categories.




Life Threatening Effects Of Antipsychotic Drugs


Life Threatening Effects Of Antipsychotic Drugs
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Author : Peter Manu
language : en
Publisher: Academic Press
Release Date : 2016-08-16

Life Threatening Effects Of Antipsychotic Drugs written by Peter Manu and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-08-16 with Medical categories.


Life-Threatening Effects of Antipsychotic Drugs describes in detail more than 20 life-threatening effects associated with antipsychotics, presents the best available data on their incidence and case fatality, and gives comprehensive advice on diagnosis, management and preventive strategies. In addition, the book discusses the benefit of antipsychotic medication in a range of therapeutic indications, and demonstrates the gain in life-expectancy associated with clozapine use in severe mental illness despite its serious, potentially life-threatening adverse effects. Covers cardiovascular, neurological, muscular, hematological, gastrointestinal, autonomic and metabolic effects Gives advice on risk factors, confounding diagnoses and measures to minimise seriousness Discusses clozapine rechallenge after each of its serious adverse reactions Makes suggestions for optimum management of somatic disease in those with severe mental illness, to improve life-expectancy Includes data on post-mortem considerations



Pharmacoeconomic Evaluation In Schizophrenia


Pharmacoeconomic Evaluation In Schizophrenia
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Author : Canadian Coordinating Office for Health Technology Assessment
language : en
Publisher: CCOHTA Publications
Release Date : 1997

Pharmacoeconomic Evaluation In Schizophrenia written by Canadian Coordinating Office for Health Technology Assessment and has been published by CCOHTA Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 1997 with categories.




Atypical Antipsychotics


Atypical Antipsychotics
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Author : Bart A. Ellenbroek
language : en
Publisher: Birkhäuser
Release Date : 2012-12-06

Atypical Antipsychotics written by Bart A. Ellenbroek and has been published by Birkhäuser this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


The introduction of chlorpromazine in 1953, and haloperidol in 1958, into clinical practice dramatically altered the therapy of schizophrenic patients. Although representing by no means a cure for this severe psychiatric ill ness, it allowed, for the first time, to adequately control the severe hallu cinations and delusional beliefs which prevent these patients from leading a more or less independent life. Indeed these antipsychotics (and the many congeners that were to follow) significantly reduced the number ofchronic schizophrenic inpatients in psychiatric clinics all over the world. However soon after their introduction it became clear that, like all other available drugs, antipsychotics were by no means miracle drugs. In fact, two major problems appeared. First, the antipsychotics had very little effect on the so-called negative or defect symptoms, like social isolation, apathy and anhedonia, and secondly virtually all antipsychotics produced a number of side-effects, of which the neurological (often called extra pyramidal) side-effects were the most troublesome. Especially the tardive dyskinesia, which occurred in about 15 to 20% of the patients after pro longed treatment, represented a major problem in the treatment of schizo phrenic patients.



The Clozapine Handbook


The Clozapine Handbook
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Author : Jonathan M. Meyer
language : en
Publisher: Cambridge University Press
Release Date : 2019-05-16

The Clozapine Handbook written by Jonathan M. Meyer and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-05-16 with Medical categories.


A practical Handbook that provides clinically-focussed approaches and guidelines on the effective management of clozapine treated patients.



Handbook Of Treatment Resistant Schizophrenia


Handbook Of Treatment Resistant Schizophrenia
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Author : Leslie Citrome
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-29

Handbook Of Treatment Resistant Schizophrenia written by Leslie Citrome and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-29 with Medical categories.


Handbook of Treatment-resistant Schizophrenia is a concise review of treatment-resistant schizophrenia’s definition, measurement tools, adherence issues, substance abuse, optimal dosing, clinician–patient relationships, and current management approaches. The book was originally commissioned with the intention of creating a comprehensive text focusing on treatment-resistant schizophrenia and its management. The book explores many aspects of the background and practice- and research-based evidence for treating this complex subset of schizophrenia, including psychopharmacological, somatic, and nonpharmacological treatment approaches. While exploring the various therapies for treatment-resistant schizophrenia, Dr Citrome also emphasizes the importance of building strong and trusting relationships between patients and their clinicians so the clinician can best manage their patient’s adherence and overall treatment.