Collaborative Computational Technologies For Biomedical Research

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Collaborative Computational Technologies For Biomedical Research
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Author : Sean Ekins
language : en
Publisher: John Wiley & Sons
Release Date : 2011-08-04
Collaborative Computational Technologies For Biomedical Research written by Sean Ekins and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-08-04 with Science categories.
Methods, Processes, and Tools for Collaboration "The time has come to fundamentally rethink how we handle the building of knowledge in biomedical sciences today. This book describes how the computational sciences have transformed into being a key knowledge broker, able to integrate and operate across divergent data types." Bryn Williams-Jones, Associate Research Fellow, Pfizer The pharmaceutical industry utilizes an extended network of partner organizations in order to discover and develop new drugs, however there is currently little guidance for managing information and resources across collaborations. Featuring contributions from the leading experts in a range of industries, Collaborative Computational Technologies for Biomedical Research provides information that will help organizations make critical decisions about managing partnerships, including: Serving as a user manual for collaborations Tackling real problems from both human collaborative and data and informatics perspectives Providing case histories of biomedical collaborations and technology-specific chapters that balance technological depth with accessibility for the non-specialist reader A must-read for anyone working in the pharmaceuticals industry or academia, this book marks a major step towards widespread collaboration facilitated by computational technologies.
Designing Knowledge Organizations
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Author : Joseph Morabito
language : en
Publisher: John Wiley & Sons
Release Date : 2017-08-14
Designing Knowledge Organizations written by Joseph Morabito and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-08-14 with Technology & Engineering categories.
A pedagogical approach to the principles and architecture of knowledge management in organizations This textbook is based on a graduate course taught at Stevens Institute of Technology. It focuses on the design and management of today's complex K organizations. A K organization is any company that generates and applies knowledge. The text takes existing ideas from organizational design and knowledge management to enhance and elevate each through harmonization with concepts from other disciplines. The authors—noted experts in the field—concentrate on both micro- and macro design and their interrelationships at individual, group, work, and organizational levels. A key feature of the textbook is an incisive discussion of the cultural, practice, and social aspects of knowledge management. The text explores the processes, tools, and infrastructures by which an organization can continuously improve, maintain, and exploit all elements of its knowledge base that are most relevant to achieve its strategic goals. The book seamlessly intertwines the disciplines of organizational design and knowledge management and offers extensive discussions, illustrative examples, student exercises, and visualizations. The following major topics are addressed: Knowledge management, intellectual capital, and knowledge systems Organizational design, behavior, and architecture Organizational strategy, change, and development Leadership and innovation Organizational culture and learning Social networking, communications, and collaboration Strategic human resources; e.g., hiring K workers and performance reviews Knowledge science, thinking, and creativity Philosophy of knowledge and information Information, knowledge, social, strategy, and contract continuums Information management and intelligent systems; e.g., business intelligence, big data, and cognitive systems Designing Knowledge Organizations takes an interdisciplinary and original approach to assess and synthesize the disciplines of knowledge management and organizational design, drawing upon conceptual underpinnings and practical experiences in these and related areas.
Recording Science In The Digital Era
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Author : Cerys Willoughby
language : en
Publisher: Royal Society of Chemistry
Release Date : 2019-07-15
Recording Science In The Digital Era written by Cerys Willoughby and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-15 with Computers categories.
For most of the history of scientific endeavour, science has been recorded on paper. In this digital era, however, there is increasing pressure to abandon paper in favour of digital tools. Despite the benefits, there are barriers to the adoption of such tools, not least their usability. As the relentless development of technology changes the way we work, we need to ensure that the design of technology not only overcomes these barriers, but facilitates us as scientists and supports better practice within science. This book examines the importance of record-keeping in science, current record-keeping practices, and the role of technology for enabling the effective capture, reuse, sharing, and preservation of scientific data. Covering the essential areas of electronic laboratory notebooks (ELNs) and digital tools for recording scientific data, including an overview of the current data management technology available and the benefits and pitfalls of using these technologies, this book is a useful tool for those interested in implementing digital data solutions within their research groups or departments. This book also provides insight into important factors to consider in the design of digital tools such as ELNs for those interested in producing their own tools. Finally, it looks at the role of current technology and then considers how that technology might develop in the future to better support scientists in their work, and in capturing and sharing the scientific record.
Governing Intellectual Property Rights Within Publicly Funded Biobanks
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Author : Rajam Neethu
language : en
Publisher: Kluwer Law International B.V.
Release Date : 2019-06-21
Governing Intellectual Property Rights Within Publicly Funded Biobanks written by Rajam Neethu and has been published by Kluwer Law International B.V. this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-21 with Law categories.
Governing Intellectual Property Rights Within Publicly Funded Biobanks R. Neethu The boom in biobanks and health databases as research infrastructures have evoked various legal and ethical debates. Since then numerous new developments have emerged such as digitalization, big-data research and artificial intelligence which has important implications for biobank-based research and collaborations. This new paradigm offers new legal challenges for commercial involvement particularly within a publicly funded setting. In this innovative book, the author shows that securing maximum social benefit out of the knowledge emanating from the use of biobank resources lies in managing intellectual property inputs and outputs effectively in keeping with the values core to such research. Focusing on the challenges of involving intellectual property rights (IPRs) particularly in the precompetitive phase of biobank-based research, the book offers an extensive understanding of the role of different IPRs and identifies the gaps in the law and its implications for biobanks. The analysis covers important aspects in relation to biobanks such as: Digital integration and biomedical data storage; Ownership of biological samples; Commercialization and benefit sharing; Partnership models; Public sector research; Disposition of samples; Consent; Cross-border exchange; Trade secrecy; Privacy; Regulatory stewardship; Business strategies; Ethical considerations over biological resources; Patenting of inventions relating to personalized medicine; Ethical parameters within patent law; and Rights regarding genetic data and databases. The book includes observations, case studies and interviews conducted by the author. In conclusion, the author offers cogent recommendations for legal interoperability of IP rules and research practices designed to enhance the ability of biobanks to share, access and reuse data. This book is the first of its kind to explore the organizational and legislative choices for biobanks particularly while engaging in the protection of research results and technology transfer within a publicly funded setting. It will be of substantial interest to all stakeholders in biobanking, especially policymakers, biobankers and researchers working in the field of health law as well as for legal practitioners, academics and patient interest groups.
In Vivo Models For Drug Discovery
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Author : José Miguel Vela
language : en
Publisher: John Wiley & Sons
Release Date : 2014-07-31
In Vivo Models For Drug Discovery written by José Miguel Vela and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-31 with Medical categories.
This one-stop reference is the first to present the complete picture -- covering all relevant organisms, from single cells to mammals, as well as all major disease areas, including neurological disorders, cancer and infectious diseases. Addressing the needs of the pharmaceutical industry, this unique handbook adopts a broad perspective on the use of animals in the early part of the drug development process, including regulatory rules and limitations, as well as numerous examples from real-life drug development projects. After a general introduction to the topic, the expert contributors from research-driven pharmaceutical companies discuss the basic considerations of using animal models, including ethical issues. The main part of the book systematically surveys the most important disease areas for current drug development, from cardiovascular to endocrine disorders, and from infectious to neurological diseases. For each area, the availability of animal models for target validation, hit finding and lead profiling is reviewed, backed by numerous examples of both successes and failures among the use of animal models. The whole is rounded off with a discussion of perspectives and challenges. Key knowledge for drug researchers in industry as well as academia.
Managing Scientific Information And Research Data
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Author : Svetla Baykoucheva
language : en
Publisher: Chandos Publishing
Release Date : 2015-07-14
Managing Scientific Information And Research Data written by Svetla Baykoucheva and has been published by Chandos Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-07-14 with Business & Economics categories.
Innovative technologies are changing the way research is performed, preserved, and communicated. Managing Scientific Information and Research Data explores how these technologies are used and provides detailed analysis of the approaches and tools developed to manage scientific information and data. Following an introduction, the book is then divided into 15 chapters discussing the changes in scientific communication; new models of publishing and peer review; ethics in scientific communication; preservation of data; discovery tools; discipline-specific practices of researchers for gathering and using scientific information; academic social networks; bibliographic management tools; information literacy and the information needs of students and researchers; the involvement of academic libraries in eScience and the new opportunities it presents to librarians; and interviews with experts in scientific information and publishing. - Promotes innovative technologies for creating, sharing and managing scientific content - Presents new models of scientific publishing, peer review, and dissemination of information - Serves as a practical guide for researchers, students, and librarians on how to discover, filter, and manage scientific information - Advocates for the adoption of unique author identifiers such as ORCID and ResearcherID - Looks into new tools that make scientific information easy to discover and manage - Shows what eScience is and why it is becoming a priority for academic libraries - Demonstrates how Electronic Laboratory Notebooks can be used to record, store, share, and manage research data - Shows how social media and the new area of Altmetrics increase researchers' visibility and measure attention to their research - Directs to sources for datasets - Provides directions on choosing and using bibliographic management tools - Critically examines the metrics used to evaluate research impact - Aids strategic thinking and informs decision making
Grid And Cloud Computing Concepts And Practical Applications
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Author : F. Carminati
language : en
Publisher: IOS Press
Release Date : 2016-05-31
Grid And Cloud Computing Concepts And Practical Applications written by F. Carminati and has been published by IOS Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-05-31 with Computers categories.
The distributed computing infrastructure known as ‘the Grid’ has undoubtedly been one of the most successful science-oriented large- scale IT projects of the past 20 years. It is now a fully operational international entity, encompassing several hundred computing sites on all continents and giving access to hundreds of thousands of CPU (central processing unit) cores and hundreds of petabytes of storage, all connected by robust national and international scientific networks. It has evolved to become the main computational platform many scientific communities. This book presents lectures from the Enrico Fermi International School of Physics summer school Grid and Cloud computing: Concepts and Practical Applications, held in Varenna, Italy, in July 2014. The school aimed to cover the conceptual and practical aspects of both the Grid and Cloud computing. The proceedings included here are divided into eight chapters, with chapters 1, 2, 3 and 8 covering general applications of Grid and Cloud computing in various scientific fields, while chapters 4, 5, 6 and 7 discuss specific technical areas of Grid and Cloud structures. The book will be of interest to all those whose work involves the use of the Grid or Cloud computing.
Handbook Of Human Computation
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Author : Pietro Michelucci
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-04
Handbook Of Human Computation written by Pietro Michelucci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-04 with Computers categories.
This volume addresses the emerging area of human computation, The chapters, written by leading international researchers, explore existing and future opportunities to combine the respective strengths of both humans and machines in order to create powerful problem-solving capabilities. The book bridges scientific communities, capturing and integrating the unique perspective and achievements of each. It coalesces contributions from industry and across related disciplines in order to motivate, define, and anticipate the future of this exciting new frontier in science and cultural evolution. Readers can expect to find valuable contributions covering Foundations; Application Domains; Techniques and Modalities; Infrastructure and Architecture; Algorithms; Participation; Analysis; Policy and Security and the Impact of Human Computation. Researchers and professionals will find the Handbook of Human Computation a valuable reference tool. The breadth of content also provides a thorough foundation for students of the field.
The Semantic Web Iswc 2013
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Author : Harith Alani
language : en
Publisher: Springer
Release Date : 2013-10-16
The Semantic Web Iswc 2013 written by Harith Alani and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-10-16 with Computers categories.
The two-volume set LNCS 8218 and 8219 constitutes the refereed proceedings of the 12th International Semantic Web Conference, ISWC 2013, held in Sydney, Australia, in October 2013. The International Semantic Web Conference is the premier forum for Semantic Web research, where cutting edge scientific results and technological innovations are presented, where problems and solutions are discussed, and where the future of this vision is being developed. It brings together specialists in fields such as artificial intelligence, databases, social networks, distributed computing, Web engineering, information systems, human-computer interaction, natural language processing, and the social sciences. Part 1 (LNCS 8218) contains a total of 45 papers which were presented in the research track. They were carefully reviewed and selected from 210 submissions. Part 2 (LNCS 8219) contains 16 papers from the in-use track which were accepted from 90 submissions. In addition, it presents 10 contributions to the evaluations and experiments track and 5 papers of the doctoral consortium.
Open Source Software In Life Science Research
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Author : Lee Harland
language : en
Publisher: Elsevier
Release Date : 2012-10-31
Open Source Software In Life Science Research written by Lee Harland and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-31 with Computers categories.
The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an 'omics' platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. - Discusses a broad range of applications from a variety of sectors - Provides a unique perspective on work normally performed behind closed doors - Highlights the criteria used to compare and assess different approaches to solving problems