Collagen In Health And Disease
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Collagen In Health And Disease
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Author : Jaqueline B. Weiss
language : en
Publisher:
Release Date : 1982
Collagen In Health And Disease written by Jaqueline B. Weiss and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
Connective Tissue In Health And Disease
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Author : Marcos Rojkind
language : en
Publisher: CRC Press
Release Date : 2017-07-28
Connective Tissue In Health And Disease written by Marcos Rojkind and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-07-28 with Medical categories.
This volume provides reviews covering the latest advances in particular areas of connective tissue research. This comprehensive work also includes areas of the medical field in which the basic aspects could be applied. It explains that both cells and matrix are altered in disease states because of the strong interactions established between cells and the extracellular matrix. The aim of this book is to close the existing gap between basic scientists and clinical investigators. This reference is an absolute must for all biological chemists, clinical investigators, and pathologists. Students of these professions will find this reading both informative and useful as well.
Nutraceuticals And The Skin Roles In Health And Disease
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Author : Jean Christopher Chamcheu
language : en
Publisher: MDPI
Release Date : 2018-10-08
Nutraceuticals And The Skin Roles In Health And Disease written by Jean Christopher Chamcheu and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-10-08 with categories.
This book is a printed edition of the Special Issue "Nutraceuticals and the Skin: Roles in Health and Disease" that was published in Nutrients
Collagen
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Author : Irit Sagi
language : en
Publisher: Humana Press
Release Date : 2019-04-06
Collagen written by Irit Sagi and has been published by Humana Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-06 with Science categories.
This detailed volume compiles state-of-the-art protocols that will serve as recipes for scientists researching collagen, an abundant protein with great importance to health and disease, as well as in applications like food, cosmetics, pharmaceuticals, cosmetic surgery, artificial skin, and glue. Beginning with a section on in vitro models for the characterization of collagen formation, the book continues by highlighting large-scale analysis of collagen with mass spectrometry in order to elucidate the proteomics, degradomics, interactomes, and cross-linking of collagen, high resolution imaging approaches for collagen by the use of scanning electron microscopy and multiphoton imaging, as well as the role of collagen during physiological and pathological conditions. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Collagen: Methods and Protocols is an ideal guide to high quality and repeatable protocols in this vital field of study.
Ultrastructure Of Skeletal Tissues
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Author : E. Bonucci
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Ultrastructure Of Skeletal Tissues written by E. Bonucci and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.
The calcified tissues have fundamental functions in the biology of organisms, not only because their strength, solidity, and elasticity permit movement and mechanical activities, and protect soft tissues against traumatic forces, but also on account of their role in mineral homeostasis. For this reason, extensive investigation in the last 30 years has provided much to explain the complex chemical and physical processes occurring in cells and matrices composing the skeleton, and their alterations in pathological conditions. The use of ultrastructural methods such as immunocytochemistry, scanning and transmission electron microscopy, cytoautoradiography, freeze/fracture etching, high voltage, etc. has proven to be of great value when applied to cells and matrix components of bone and cartilage, in spite of the technical difficulties due to the hardness of these tissues. However, available information on this subject is disseminated in a variety of scientific and medical articles. This volume is an attempt to collect together the most significant data on the ultrastructure of cartilage and bone in normalcy and pathology. Obviously, it cannot be a complete report of all these data, its principal aim being that of: a) giving a comprehensive statement of the results concerning the basic structures common to these tissues, especially collagen fibrils, noncollagenous proteins, and proteoglycans, and their relationships with the mineral substance (for which another volume of this series can also be consulted; see Ruggeri A. , Motta P. M. (eds.
The Collagens Biochemistry And Pathophysiology
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Author : Eugene J. Kucharz
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
The Collagens Biochemistry And Pathophysiology written by Eugene J. Kucharz and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
This book describes every manner in which collagen is involved in normal anddisease-altered states of the various organs and systems. In the first part of the book the biochemical aspects of collagens are reviewed, including their structure, heterogeneity, syntheses, and degradation. The main part focuses on the involvement of collagen in bone, cartilage, tendon, muscle, heart, vessels, lungs, liver, skin, eye, ear, teeth, periodontal tissues, kidneys and reproductive, hemopoietic,and nervous systems. The influence of radiation and nutrition on collagen, the role of collagen in neoplasms, the hormonal control of its metabolism, immunobiology and the pharmacology of collagen are also described. The most important feature of the book is the comprehensive review of the medical aspects of collagen, from those known in detail to those only hypothesized including hereditary disorders affecting collagen and so-called collagen diseases. Each chapter reviewsknown or possible mechanisms of collagen involvement and changes in indices of collagen which can be measured in clinical practice to monitor these phenomena. The fact that collagen is involved into the pathophysiology of almost all organs and body systems means that physicians in almost all branches of medicine will find this book of great interest.
Fibrocytes In Health And Disease
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Author : Richard Bucala
language : en
Publisher: World Scientific
Release Date : 2012
Fibrocytes In Health And Disease written by Richard Bucala and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Medical categories.
This volume provides a comprehensive and multidisciplinary overview of fibrocytes, written by the main researchers in the field. It is aimed at a broad audience of scientists and clinicians with an interest in the role of circulating fibrocytes in the etiopathogenesis of different fibrosing disorders, atherosclerosis, autoimmunity, and cancer.
Vitamin C In Health And Disease
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Author : Anitra C. Carr
language : en
Publisher: MDPI
Release Date : 2018-08-09
Vitamin C In Health And Disease written by Anitra C. Carr and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-08-09 with Electronic books categories.
This book is a printed edition of the Special Issue "Vitamin C in Health and Disease" that was published in Nutrients
The Periodontal Ligament In Health And Disease
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Author : B. J. Moxham
language : en
Publisher: Pergamon
Release Date : 1982
The Periodontal Ligament In Health And Disease written by B. J. Moxham and has been published by Pergamon this book supported file pdf, txt, epub, kindle and other format this book has been release on 1982 with Medical categories.
Discoidin Domain Receptors In Health And Disease
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Author : Rafael Fridman
language : en
Publisher: Springer
Release Date : 2018-06-09
Discoidin Domain Receptors In Health And Disease written by Rafael Fridman and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-06-09 with Medical categories.
The interactions of cells with their surrounding extracellular matrix (ECM) plays a pivotal role in driving normal cell behavior, from development to tissue differentiation and function. At the cellular level, organ homeostasis depends on a productive communication between cells and ECM, which eventually leads to the normal phenotypic repertoire that characterize each cell type in the organism. A failure to establish these normal interactions and to interpret the cues emanating from the ECM is one of the major causes in abnormal development and the pathogenesis of multiple diseases. To recognize and act upon the biophysical signals that are generated by the cross talk between cells and ECM, the cells developed specific receptors, among them a unique set of receptor tyrosine kinases (RTKs), known as the Discoidin Domain Receptors (DDRs). The DDRs are the only RTKs that specifically bind to and are activated by collagen, a major protein component of the ECM. Hence, the DDRs are part of the signaling networks that translate information from the ECM, and thus they are key regulators of cell-matrix interactions. Under physiological conditions, DDRs control cell and tissue homeostasis by acting on collagen sensors; transducing signals that regulate cell polarity, tissue morphogenesis, cell differentiation, and collagen deposition. DDRs play a key role in diseases that are characterized by dysfunction of the stromal component, which lead to abnormal collagen deposition and the resulting fibrotic response that disrupt normal organ function in disease of the cardiovascular system, lungs and kidneys, just to mention a few. In cancer, DDRs are hijacked by tumor and stromal cells to disrupt normal cell-collagen communication and initiate pro-oncogenic programs. Importantly, several cancer types exhibit DDR mutations, which are thought to alter receptor function, and contribute to cancer progression. Therefore, the strong causative association between altered RTK function and disease it is been translated today in the development of specific tyrosine kinase inhibitors targeting DDRs for various disease conditions. In spite of the accumulating evidence highlighting the importance of DDRs in health and diseases, there is still much to learn about these unique RTKs, as of today there is a lack in the medical literature of a book dedicated solely to DDRs. This is the first comprehensive volume dedicated to DDRs, which will fill a gap in the field and serve those interested in the scientific community to learn more about these important receptors in health and disease.