Combating Fungal Infections
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Combating Fungal Infections
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Author : Iqbal Ahmad
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-08-03
Combating Fungal Infections written by Iqbal Ahmad and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-03 with Medical categories.
Fungi are eukaryotic microorganisms that are closely related to humans at cellular level. Human fungal pathogens belong to various classes of fungi, mainly zygo- cetes, ascomycetes, basidiomycetes, and deuteromycetes. In recent years, fungal infections have dramatically increased as a result of improved diagnosis, high frequency of catheterization, instrumentation, etc. However, the main cause remains the increasing number of immunosuppressed patients, mostly because of HIV infection and indiscriminate usage of antineoplastic and immunosuppressive agents, broad-spectrum antibiotics and prosthetic devices, and grafts in clinical settings. Presently available means of combating fungal infections are still weak and clumsy compared to control of bacterial infection. The present scenario of antifungal therapy is still based on two classes of antifungal drugs (polyenes and azoles). These drugs are effective in many cases, but display toxicity and limited spectrum of ef?cacy. The recent trend towards emergence of drug-resistant isolates in the clinic is an additional problem. In recent years, a few new antifungal drugs have entered the clinics, but they are expected to undergo same fate as the older antifungal drugs. The application of fungal genomics offers an unparalleled opportunity to develop novel antifungal drugs. However, it is too early to expect any novel drugs, as the antifungal drug discovery program is in the stage of infancy. Interestingly, several novel antifungal drug targets have been identi?ed and validated.
Immunology Of Fungal Infections
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Author : Gordon D. Brown
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-05-10
Immunology Of Fungal Infections written by Gordon D. Brown and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-05-10 with Medical categories.
This text covers all aspects of the immunology of fungal infection. Beyond the basics, coverage includes recent developments in innate and adaptive immunological mechanisms involved in the host response to fungal infection. The volume’s topical sections provide an immunological perspective on the cells, soluble factors and receptors involved in recognising and combating fungal infections. Discussion includes descriptions of immunity to specific pathogens, immune-escape mechanisms used by fungi, and therapeutic strategies.
Antifungal Drug Discovery New Theories And New Therapies
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Author :
language : en
Publisher:
Release Date : 2016
Antifungal Drug Discovery New Theories And New Therapies written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016 with categories.
Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.
Antifungal Drug Discovery New Theories And New Therapies
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Author : Chaminda Jayampath Seneviratne
language : en
Publisher: Frontiers Media SA
Release Date : 2016-09-13
Antifungal Drug Discovery New Theories And New Therapies written by Chaminda Jayampath Seneviratne and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-13 with Microbiology categories.
Fungal infections such as candidoses can range from superficial mucous membrane infection to life-threatening systemic mycoses. Candida infections are a significant clinical problem globally due to rapid rise in compromised host populations including HIV/AIDS, organ transplant recipients and patients on chemotherapy. In addition, sharp increase in aging populations which are susceptible to fungal infections is expected in next few decades. Antifungal drugs are relatively difficult to develop compared to the antibacterial drugs owing to the eukaryotic nature of the cells. Therefore, only a handful of antifungal agents are currently available to treat the myriad of fungal infections. Moreover, rising antifungal resistance and host-related adverse reactions have limited the antifungal arsenal against fungal pathogens. In this research topic, we tried to update the theoretical aspects pertaining to the antifungal drug discovery i.e. proposed novel mechanisms, new drug targets and pathways. In addition, invited authors explored the new antifungal drugs derived from natural and synthetic sources which are currently under development. Contributors were encouraged to bring new insight into the antifungal drug discovery. We hope the reader may arrive at a general consensus on the possible strategies to combat ever increasing ubiquitous fungal infection in this new century.
Clinical Approach To Fungal Infections
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Author : Kabir Sardana MD, DNB, MNAMS
language : en
Publisher: CBS Publishers & Distributors Private Limited
Release Date : 2019-06-30
Clinical Approach To Fungal Infections written by Kabir Sardana MD, DNB, MNAMS and has been published by CBS Publishers & Distributors Private Limited this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-30 with categories.
This is the first book on fungal infections of the skin pertaining to the Indian conditions. It covers all important aspects of the topics, including superficial and deep systemic fungal infection and anti fungal drugs.
Diagnosis And Treatment Of Fungal Infections
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Author : Duane R. Hospenthal
language : en
Publisher: Springer Nature
Release Date : 2023-09-14
Diagnosis And Treatment Of Fungal Infections written by Duane R. Hospenthal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-14 with Medical categories.
Diagnosis and Treatment of Fungal Infections, 3rd Edition contains the latest research and clinical evidence on fungal infections in humans. Updated again by globally recognized experts, this concise text is divided into sections dedicated to the patient approach, laboratory and radiological diagnosis, systemic antifungal agents, mycoses, and instructive cases. It is a concise but comprehensive resource for use in conjunction with patient care duties and in teaching. It is the perfect guide for hospital-based primary care physicians, oncologists, critical care specialists, and infectious disease fellows with limited training or experience in the identification and management of fungal infections.
Pocket Guide To Fungal Infection
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Author : Malcolm D. Richardson
language : en
Publisher: John Wiley & Sons
Release Date : 2008-05-12
Pocket Guide To Fungal Infection written by Malcolm D. Richardson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-05-12 with Medical categories.
The Pocket Guide to Fungal Infection presents, in a convenient and practical format, the major features of fungal infections in humans, providing visual information for each pathogen and the infections they cause. The second edition has been extensively revised. In each chapter the clinical manifestations and management sections have been revised and updated to include recently developed antifungal drugs. New sections include; Emerging yeast and filamentous fungal pathogens Antifungal susceptibility testing Antifungal assays Molecular methods in medical mycology Mycological aspects of the indoor environment. Medical Mycology lends itself to illustration and as such there are over 40 additional images in this edition. Recent references have been added and the list of online resources has been updated. This Guide presents a succinct account of the clinical manifestations, laboratory diagnosis and management of fungal infections world-wide. It is an ideal publication for those who encounter fungal infections as part of their everyday practice, including medical microbiologists, infectious disease specialists, dermatologists and general practitioners.
Antifungal Therapy
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Author : Mahmoud Ghannoum
language : en
Publisher: CRC Press
Release Date : 2016-04-19
Antifungal Therapy written by Mahmoud Ghannoum and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-19 with Medical categories.
A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy. This book provides a c
Fungal Infection
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Author : Malcolm D. Richardson
language : en
Publisher: John Wiley & Sons
Release Date : 2012-01-05
Fungal Infection written by Malcolm D. Richardson and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-05 with Medical categories.
Fungal Infection: Diagnosis and Management, 4th Edition is a concise and up-to-date guide to the clinical manifestations, laboratory diagnosis and management of superficial, subcutaneous and systemic fungal infections. This highly acclaimed book has been extensively revised and updated throughout to ensure all drug and dosage recommendations are accurate and in agreement with current guidelines. A new chapter on infections caused by Pneumocystis jirovecii has been added. The book has been designed to enable rapid information retrieval and to help clinicians make informed decisions about diagnosis and patient management. Each chapter concludes with a list of recent key publications which have been carefully selected to facilitate efficient access to further information on specific aspects of fungal infections. Clinical microbiologists, infectious disease specialists, as well as dermatologists, hematologists and oncologists, can depend on this contemporary text for authoritative information and the background necessary to understand fungal infections.
Recent Trends In Antifungal Agents And Antifungal Therapy
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Author : Amit Basak
language : en
Publisher: Springer
Release Date : 2016-09-21
Recent Trends In Antifungal Agents And Antifungal Therapy written by Amit Basak and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-21 with Science categories.
Fungal infections have taken a new spectrum due to the increased incidence of multi-drug resistant fungal pathogens. Freedom of choice for drugs to treat fungal infections is also narrow because of lesser probability of discovering drugs that would bypass affecting human cells and target fungal cells producing fewer side effects in patients. An approach has gained prominence in research is to look for bioactive antifungal compounds from natural to synthetic sources. It is necessary to discover new classes of antifungals to control the recent emergence of multi-drug resistant fungal infections. This book proposed a details top to bottom outline of antifungal compounds derived naturally or synthetically. The details of their modifications or synthetic analogues have been described, helpful to understand the structure-activity relationship which leads to new compound development in antifungal chemotherapy. Each chapter begins with a comprehensive, top-bottom in-depth discussion of antifungal agents with updated bibliographic references. This compendium will serve as a companion not only for Scientists, Researchers, and Professors, Medical Practitioners but also a valuable reference text for the university students.