Combating The Threat Of Pandemic Influenza

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Combating The Threat Of Pandemic Influenza

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Author : Paul F. Torrence
language : en
Publisher: John Wiley & Sons
Release Date : 2007-09-28

Combating The Threat Of Pandemic Influenza written by Paul F. Torrence and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-28 with Medical categories.

Drug discovery for influenza antivirals Priorities for combating pandemic influenza include rapid detection and identification, the quick administration of available drugs to treat the infection, the development of new antivirals, and the development of vaccines. Since lead-time may be required to produce an effective vaccine, antivirals would serve as a key first line of defense in containing an outbreak. Diverse antivirals, acting through different mechanisms, would help stay the development of resistant viruses. Thus, drug discovery for influenza antivirals is an important public health–related endeavor. With chapters contributed by leading international specialists, this guide gets readers up to speed on the latest advances and technologies in diverse approaches to drug discovery, covering: Existing antivirals, including broadly effective anti-respiratory virus agents The development of high-throughput screening assays IFN resistance The development of nucleic acid–based antiviral drugs Antiviral RNAi strategies targeting influenza virus Other promising antiviral drug discovery strategies Combating the Threat of Pandemic Influenza: Drug Discovery Approaches consolidates the latest information on diverse approaches into one comprehensive resource. It is an invaluable, hands-on reference for researchers in medicinal chemistry, pharmaceutical chemistry, drug discovery, biochemistry, virology, microbiology, and public health.

Countering The Pandemic Threat Through Global Coordination On Vaccines The Influenza Imperative

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Author : National Academy of Medicine
language : en
Publisher: National Academies Press
Release Date : 2021-12-31

Countering The Pandemic Threat Through Global Coordination On Vaccines The Influenza Imperative written by National Academy of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-31 with Medical categories.

The COVID-19 pandemic has laid bare the fragility of the global system of preparedness and response to pandemics and the fragmentation of our research and development ecosystem. The pandemic has provided a disruptive moment to advance new norms and frameworks for influenza. It also has demonstrated how innovative global public-private partnerships and coordination mechanisms can lead to rapid successes in viral vaccine research, manufacturing, and risk pooling. Countering the Pandemic Threat Through Global Coordination on Vaccines identifies ways to strengthen pandemic and seasonal influenza global coordination, partnerships, and financing. This report presents seven overarching recommendations for how the urgent influenza threat should be conceptualized and prioritized within the global pandemic preparedness and response agenda in the future.

The Threat Of Pandemic Influenza

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Author : Institute of Medicine
language : en
Publisher: National Academies Press
Release Date : 2005-04-09

The Threat Of Pandemic Influenza written by Institute of Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-04-09 with Medical categories.

Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

Influenza Pandemic And Steps To Counter It

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Author : Government Accountability Office Office
language : en
Publisher: Nova Science Publishers
Release Date : 2008

Influenza Pandemic And Steps To Counter It written by Government Accountability Office Office and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with Influenza categories.

Pandemic influenza poses a threat to public health at a time when the United Nations' World Health Organization (WHO) has said that infectious diseases are spreading faster than at any time in history. The last major influenza pandemic occurred from 1918 to 1919. Estimates of deaths worldwide if a similar pandemic were to occur have ranged between 30 million and 384 million people. Individual countries and international organisations have developed and begun to implement a strategy for forestalling (that is, containing, delaying, or minimising the impact of) the onset of a pandemic. Antivirals and vaccines may help forestall a pandemic. This is an excerpted and indexed version.

Microbial Threats To Health

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Author : Institute of Medicine (U.S.). Committee on Emerging Microbial Threats to Health in the 21st Century
language : en
Publisher:
Release Date : 2005

Microbial Threats To Health written by Institute of Medicine (U.S.). Committee on Emerging Microbial Threats to Health in the 21st Century and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Epidemics categories.

Flu

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Author : Gina Kolata
language : en
Publisher: Farrar, Straus and Giroux
Release Date : 2011-04-01

Flu written by Gina Kolata and has been published by Farrar, Straus and Giroux this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04-01 with Social Science categories.

Veteran journalist Gina Kolata's Flu: The Story of the Great Influenza Pandemic of 1918 and the Search for the Virus That Caused It presents a fascinating look at true story of the world's deadliest disease. In 1918, the Great Flu Epidemic felled the young and healthy virtually overnight. An estimated forty million people died as the epidemic raged. Children were left orphaned and families were devastated. As many American soldiers were killed by the 1918 flu as were killed in battle during World War I. And no area of the globe was safe. Eskimos living in remote outposts in the frozen tundra were sickened and killed by the flu in such numbers that entire villages were wiped out. Scientists have recently rediscovered shards of the flu virus frozen in Alaska and preserved in scraps of tissue in a government warehouse. Gina Kolata, an acclaimed reporter for The New York Times, unravels the mystery of this lethal virus with the high drama of a great adventure story. Delving into the history of the flu and previous epidemics, detailing the science and the latest understanding of this mortal disease, Kolata addresses the prospects for a great epidemic recurring, and, most important, what can be done to prevent it.

National Strategy For Pandemic Influenza

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Author :
language : en
Publisher:
Release Date : 2005

National Strategy For Pandemic Influenza written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Emergency management categories.

"Once again, nature has presented us with a daunting challenge: the possibility of an influenza pandemic. Scientists and doctors cannot tell us where or when the next pandemic will strike, or how severe it will be, but most agree: at some point, we are likely to face another pandemic. And the scientific community is increasingly concerned by a new influenza virus known as H5N1 -- or avian flu -- that is now spreading through bird populations across Asia, and has recently reached Europe. While avian flu has not yet acquired the ability to spread easily from human to human, there is still cause for vigilance. The virus has developed some characteristics needed to cause a pandemic: It has demonstrated the ability to infect human beings, and it has produced a fatal illness in humans. If the virus were to develop the capacity for sustained human-to-human transmission, it could spread quickly across the globe. Our country has been given fair warning of this danger to our homeland -- and time to prepare. My administration has developed a comprehensive national strategy, with concrete measures we can take to prepare for an influenza pandemic. Our strategy is designed to meet three critical goals: First, we must detect outbreaks that occur anywhere in the world; second, we must protect the American people by stockpiling vaccines and antiviral drugs, and improve our ability to rapidly produce new vaccines against a pandemic strain; and, third, we must be ready to respond at the federal, state and local levels in the event that a pandemic reaches our shores."--President George Bush.

Pandemic Influenza Preparedness And Response

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Author : World Health Organization
language : en
Publisher: World Health Organization
Release Date : 2009

Pandemic Influenza Preparedness And Response written by World Health Organization and has been published by World Health Organization this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009 with Medical categories.

This guidance is an update of WHO global influenza preparedness plan: the role of WHO and recommendations for national measures before and during pandemics, published March 2005 (WHO/CDS/CSR/GIP/2005.5).

Exploring Lessons Learned From A Century Of Outbreaks

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Author : National Academies of Sciences, Engineering, and Medicine
language : en
Publisher: National Academies Press
Release Date : 2019-06-05

Exploring Lessons Learned From A Century Of Outbreaks written by National Academies of Sciences, Engineering, and Medicine and has been published by National Academies Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-06-05 with Medical categories.

In November 2018, an ad hoc planning committee at the National Academies of Sciences, Engineering, and Medicine planned two sister workshops held in Washington, DC, to examine the lessons from influenza pandemics and other major outbreaks, understand the extent to which the lessons have been learned, and discuss how they could be applied further to ensure that countries are sufficiently ready for future pandemics. This publication summarizes the presentations and discussions from both workshops.

Disease Control Priorities Third Edition Volume 9

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Author : Dean T. Jamison
language : en
Publisher: World Bank Publications
Release Date : 2017-12-06

Disease Control Priorities Third Edition Volume 9 written by Dean T. Jamison and has been published by World Bank Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-06 with Medical categories.

As the culminating volume in the DCP3 series, volume 9 will provide an overview of DCP3 findings and methods, a summary of messages and substantive lessons to be taken from DCP3, and a further discussion of cross-cutting and synthesizing topics across the first eight volumes. The introductory chapters (1-3) in this volume take as their starting point the elements of the Essential Packages presented in the overview chapters of each volume. First, the chapter on intersectoral policy priorities for health includes fiscal and intersectoral policies and assembles a subset of the population policies and applies strict criteria for a low-income setting in order to propose a "highest-priority" essential package. Second, the chapter on packages of care and delivery platforms for universal health coverage (UHC) includes health sector interventions, primarily clinical and public health services, and uses the same approach to propose a highest priority package of interventions and policies that meet similar criteria, provides cost estimates, and describes a pathway to UHC.