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Comparative Genomics


Comparative Genomics
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Comparative Genomics


Comparative Genomics
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Author : João Carlos Setubal
language : en
Publisher: Springer Nature
Release Date : 2024-05-31

Comparative Genomics written by João Carlos Setubal and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-05-31 with Science categories.


This second edition provides new and updated chapters covering computational and mathematical techniques and concepts related to the field of comparative genomics. The topics covered in the chapters range from those that address general techniques and concepts that apply to all organisms to others that are specialized and apply to specific biological systems such as viruses, bacteria, nematodes, and insects. Well-known comparative genomics web-based platforms are also covered in specific chapters. Written in the highly successful Methods in Molecular Biology series format, many chapters include introductions to their respective topics and step-by-step comparison procedures, demonstrated on actual sets of genome sequences. Authoritative and cutting-edge, Comparative Genomics: Methods and Protocols, Second Edition aims to ensure successful results in the further study of this vital field.



Comparative Genomics


Comparative Genomics
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Author : Nicholas H. Bergman
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-11-29

Comparative Genomics written by Nicholas H. Bergman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-11-29 with Medical categories.


This volume provides a collection of robust protocols for molecular biologists studying comparative genomics. Given the tremendous increase in available biosequence data over the past ten years, this volume is timely, comprehensive, and novel. The volume is intended for molecular biologists, biochemists and geneticists.



Foundations Of Comparative Genomics


Foundations Of Comparative Genomics
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Author : Arcady R. Mushegian
language : en
Publisher: Elsevier
Release Date : 2010-07-20

Foundations Of Comparative Genomics written by Arcady R. Mushegian and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-07-20 with Science categories.


This book provides an overview of computational analysis of genes and genomes, and of some most notable findings that come out of this work. Foundations of Comparative Genomics presents a historical perspective, beginning with early analysis of individual gene sequences, to present day comparison of gene repertoires encoded by completely sequenced genomes. The author discusses the underlying scientific principles of comparative genomics, argues that completion of many genome sequences started a new era in biology, and provides a personal view on several state-of-the-art issues, such as systems biology and whole-genome phylogenetic reconstructions. This book is an essential reference for researchers and students in computational biology, evolutionary biology, and genetics. - Presents an historic overview of genome biology and its achievements - Includes topics not covered in other books such as minimal and ancestral genomes - Discusses the evolutionary resilience of protein-coding genes and frequent functional convergence at the molecular level - Critically reviews horizontal gene transfer and other contentious issues - Covers comparative virology as a somewhat overlooked foundation of modern genome science



Comparative Genomics


Comparative Genomics
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Author : Xuhua Xia
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08

Comparative Genomics written by Xuhua Xia and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Science categories.


This book provides an evolutionary conceptual framework for comparative genomics, with the ultimate objective of understanding the loss and gain of genes during evolution, the interactions among gene products, and the relationship between genotype, phenotype and the environment. The many examples in the book have been carefully chosen from primary research literature based on two criteria: their biological insight and their pedagogical merit. The phylogeny-based comparative methods, involving both continuous and discrete variables, often represent a stumbling block for many students entering the field of comparative genomics. They are numerically illustrated and explained in great detail. The book is intended for researchers new to the field, i.e., advanced undergraduate students, postgraduates and postdoctoral fellows, although professional researchers who are not in the area of comparative genomics will also find the book informative.



Comparative Genomics


Comparative Genomics
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Author : Melody Clark
language : en
Publisher: Springer Science & Business Media
Release Date : 2000-11-30

Comparative Genomics written by Melody Clark and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-11-30 with Medical categories.


Comparative genomics: an introduction: sequencing projects and model organisms (M. S. Clark). Drosophila melanogaster: a genetic tool (U. Schafer, H. Jackle). Tunicates: models for chordate evolution and development at low genomic complexity (W. R. Jeffrey). Fugu rubripes: a fish model genome (M. S. Clark, G. Elgar). The mouse and the genomic era (T. J. Wilson, F. Lazner, I. Kola, P. J. Hertzog). Quantitative Trait Loci in domestic animals - complex inheritance patterns (E. Lipkin, m. Soller). Comparative genomics of vertebrates and the evolution of sex chromosomes (J. A. M. Graves, S. Shetty). Insights into mammalian genome organization evolution by molecular cytogenetics (J. Wienberg, L. Froniecke, R. Stanyon). Index.



Comparative Genomics


Comparative Genomics
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Author : Aoife McLysaght
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-09-06

Comparative Genomics written by Aoife McLysaght and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-09-06 with Science categories.


This book constitutes the refereed proceedings of the RECOMB 2005 Satellite Workshop, the 3rd RECOMB Comparative Genomics meeting RCG 2005, held in Dublin, Ireland in September 2005. The 14 revised full papers presented were carefully reviewed and selected from 21 initial submissions. The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from new quantitative discoveries about genome structure and process to theorems on the complexity of computational problems inspired by genome comparison.



Comparative Genomics


Comparative Genomics
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Author : Francesca D. Ciccarelli
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-09-29

Comparative Genomics written by Francesca D. Ciccarelli and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-29 with Science categories.


As genome-sequencing costs continue their downward spiral, sequencing of closely related organisms has become increasingly a?ordable. The growing amount of genomic data available demands for the constant development of computational tools to be applied in comparative genomics. The RECOMB Workshop on C- parative Genomics (RECOMB-CG) is devoted to bringing together scientists working on all aspects of comparative genomics, from computer scientists, ma- ematicians and statisticians working on novel computational approaches for genome analysis and comparison, to biologists applying these computational tools to study the structure and the evolution of prokaryotic and eukaryotic genomes. This volume contains the 19 papers presented at the 7th Annual RECOMB-CG workshop held during September 27–29, 2009 at the Renyi Institute, in Budapest, Hungary. The papers published in these proceedings were selected for oral p- sentation from 31 submissions from scientists around the world. Each paper was reviewed by at least three members of the Program Committee in a stringent and thoughtful peer-review process.



Comparative Genomics


Comparative Genomics
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Author : Guillaume Bourque
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-09-19

Comparative Genomics written by Guillaume Bourque and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-09-19 with Science categories.


This book constitutes the refereed proceedings of the 4th RECOMB Comparative Genomics Satellite Workshop, RECOMB-CG 2006. The 17 revised full papers presented were carefully reviewed and selected from 34 initial submissions. The papers address a broad variety of aspects and components of the field of comparative genomics, ranging from new quantitative discoveries about genome structure and process to theorems on the complexity of computational problems inspired by genome comparison.



Comparative Genomics


Comparative Genomics
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Author : Eric Tannier
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-10-06

Comparative Genomics written by Eric Tannier and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-10-06 with Science categories.


The complexity of genome evolution has given birth to exciting challenges for computational biologists. A various range of algorithmic, statistical, mathem- ical techniques to elucidate the histories of molecules are developed each year and many are presented at the RECOMB satellite workshop on Comparative Genomics. It is a place where scientists working on all aspects of comparative genomics can share ideas on the development of tools and their application to relevant questions. This volume contains the papers presented at RECOMB-CG 2010, held on October 9–11 in Ottawa. The ?eld is still ?ourishing as seen from the papers presented this year: many developments enrich the combinatorics of genome rearrangements, while gene order phylogenies are becoming more and more - curate, thanks to a mixing of combinatorial and statistical principles, associated with rapid and thoughtful heuristics. Several papers tend to re?ne the models of genome evolution, and more and more genomic events can be modeled, from single nucleotide substitutions in whole genome alignments to large structural mutations or horizontal gene transfers.



Comparative Genomics


Comparative Genomics
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Author : D. Sankoff
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Comparative Genomics written by D. Sankoff and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


A comprehensive account of genomic rearrangement, focusing on the mechanisms of inversion, translocation, gene and genome duplication and gene transfer and on the patterns that result from them in comparative maps. Includes analyses of genomic sequences in organelles, prokaryotes and eukaryotes as well as comparative maps of the nuclear genomes in higher plants and animals. The book showcases a variety of algorithmic and statistical approaches to rearrangement and map data.