Complex Enzymes In Microbial Natural Product Biosynthesis Part B Polyketides Aminocoumarins And Carbohydrates
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Complex Enzymes In Microbial Natural Product Biosynthesis Part B Polyketides Aminocoumarins And Carbohydrates
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-04-11
Complex Enzymes In Microbial Natural Product Biosynthesis Part B Polyketides Aminocoumarins And Carbohydrates written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-11 with Science categories.
Microbial natural products have been an important traditional source of valuable antibiotics and other drugs but interest in them waned in the 1990s when big pharma decided that their discovery was no longer cost-effective and concentrated instead on synthetic chemistry as a source of novel compounds, often with disappointing results. Moreover understanding the biosynthesis of complex natural products was frustratingly difficult. With the development of molecular genetic methods to isolate and manipulate the complex microbial enzymes that make natural products, unexpected chemistry has been revealed and interest in the compounds has again flowered. This two-volume treatment of the subject will showcase the most important chemical classes of complex natural products: the peptides, made by the assembly of short chains of amino acid subunits, and the polyketides, assembled from the joining of small carboxylic acids such as acetate and malonate. In both classes, variation in sub-unit structure, number and chemical modification leads to an almost infinite variety of final structures, accounting for the huge importance of the compounds in nature and medicine. Gathers tried and tested methods and techniques from top players in the field Provides an extremely useful reference for the experienced research scientist Covers biosynthesis of Polyketides, Tarpenoids, Aminocoumarins and Crabohydrates
Natural Product Biosynthesis By Microorganisms And Plants Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-10-01
Natural Product Biosynthesis By Microorganisms And Plants Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-01 with Science categories.
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The second of 3 volumes covering Natural product biosynthesis by microorganisms and plants. - This new volume continues the legacy of this premier serial - Contains quality chapters authored by leaders in the field - The second of 3 volumes it has chapters on such topics as biological chlorination, bromination and iodination, and phylogenetic approaches to natural product structure prediction
Natural Product Biosynthesis By Microorganisms And Plants Part A
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Natural Product Biosynthesis By Microorganisms And Plants Part A written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The first of 3 volumes covering Natural product biosynthesis by microorganisms and plants, it has chapters on such topics as Kinetics of plant sesquiterpene synthases, Terpenoid biosynthesis in fungi, and plant Type III polyketide synthases. - Contains quality chapters authored by leaders in the field - The first of 3 volumes - Has chapters on such topics as kinetics of plant sesquiterpene synthases, terpenoid biosynthesis in fungi, and plant Type III polyketide synthases
Natural Product Biosynthesis By Microorganisms And Plants Part C
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-12-31
Natural Product Biosynthesis By Microorganisms And Plants Part C written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.
This new volume of Methods in Enzymology continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. The third of 3 volumes covering Natural product biosynthesis by microorganisms and plants. - This new volume continues the legacy of this premier serial - Contains quality chapters authored by leaders in the field - The third of 3 volumes, it has chapters on such topics as metabolic pathways in Aspergillus oryzae, heterologous gene clusters and cyanobacteria as a source of natural products
Natural Product Biosynthesis By Microorganisms And Plants
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Author : D. A. Hopwood
language : en
Publisher: Academic Press
Release Date : 2012
Natural Product Biosynthesis By Microorganisms And Plants written by D. A. Hopwood and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Alkaloids categories.
Annotation This volume of 'Methods in Enzymology' continues the legacy of this premier serial by containing quality chapters authored by leaders in the field.
Methods In Methane Metabolism Part B
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Author : Amy Rosenzweig
language : en
Publisher: Academic Press
Release Date : 2011-03-17
Methods In Methane Metabolism Part B written by Amy Rosenzweig and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-03-17 with Science categories.
Produced by microbes on a large scale, methane is an important alternative fuel as well as a potent greenhouse gas. This volume focuses on microbial methane metabolism, which is central to the global carbon cycle. Both methanotrophy and methanogenesis are covered in detail. Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems, and field measurements. The state of the art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field. - Topics include isolation and classification of microorganisms, metagenomics approaches, biochemistry of key metabolic enzymes, gene regulation and genetic systems and field measurements - The state-of-the-art techniques described here will both guide researchers in specific pursuits and educate the wider scientific community about this exciting and rapidly developing field
Biothermodynamics Part B
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Author : Michael L. Johnson
language : en
Publisher: Academic Press
Release Date : 2009-11-11
Biothermodynamics Part B written by Michael L. Johnson and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-11 with Science categories.
The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. - Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules - Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research - Offers step-by-step lab instructions, including necessary equipment, from a global research community
Computer Methods Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2009-11-05
Computer Methods Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-11-05 with Medical categories.
The combination of faster, more advanced computers and more quantitatively oriented biomedical researchers has recently yielded new and more precise methods for the analysis of biomedical data. These better analyses have enhanced the conclusions that can be drawn from biomedical data, and they have changed the way that experiments are designed and performed. This volume, along with previous and forthcoming Computer Methods volumes for the Methods in Enzymology serial, aims to inform biomedical researchers about recent applications of modern data analysis and simulation methods as applied to biomedical research. - Presents step-by-step computer methods and discusses the techniques in detail to enable their implementation in solving a wide range of problems - Informs biomedical researchers of the modern data analysis methods that have developed alongside computer hardware - Presents methods at the "nuts and bolts" level to identify and resolve a problem and analyze what the results mean
Synthetic Biology Part B
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Author : Chris Voigt
language : en
Publisher: Academic Press
Release Date : 2011-07-15
Synthetic Biology Part B written by Chris Voigt and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-15 with Science categories.
Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. - Encompasses a variety of different approaches, methodologies and disciplines - Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation
Protein Engineering For Therapeutics Part B
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Author :
language : en
Publisher: Academic Press
Release Date : 2012-01-25
Protein Engineering For Therapeutics Part B written by and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-01-25 with Technology & Engineering categories.
This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffolds - Chapters provide an invaluable resource for academics, researchers and students alike - Iinternational board of authors - This volume is split into sections that cover subjects such as peptides, and scaffolds