Comprehensive Chirality

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Comprehensive Chirality

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Author :
language : en
Publisher: Newnes
Release Date : 2012-12-31

Comprehensive Chirality written by and has been published by Newnes this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-31 with Science categories.

Although many books exist on the subject of chiral chemistry, they only briefly cover chiral synthesis and analysis as a minor part of a larger work, to date there are none that pull together the background information and latest advances in one comprehensive reference work. Comprehensive Chirality provides a complete overview of the field, and includes chiral research relevant to synthesis, analytic chemistry, catalysis, and pharmaceuticals. The individual chapters in each of the 9 volumes provide an in depth review and collection of references on definition, technology, applications and a guide/links to the related literature. Whether in an Academic or Corporate setting, these chapters will form an invaluable resource for advanced students/researchers new to an area and those who need further background or answers to a particular problem, particularly in the development of drugs. Chirality research today is a central theme in chemistry and biology and is growing in importance across a number of disciplinary boundaries. These studies do not always share a unique identifying factor or subject themselves to clear and concise definitions. This work unites the different areas of research and allows anyone working or researching in chiral chemistry to navigate through the most essential concepts with ease, saving them time and vastly improving their understanding. The field of chirality counts several journals that are directly and indirectly concerned with the field. There is no reference work that encompasses the entire field and unites the different areas of research through deep foundational reviews. Comprehensive Chirality fills this vacuum, and can be considered the definitive work. It will help users apply context to the diverse journal literature offering and aid them in identifying areas for further research and/or for solving problems. Chief Editors, Hisashi Yamamoto (University of Chicago) and Erick Carreira (ETH Zürich) have assembled an impressive, world-class team of Volume Editors and Contributing Authors. Each chapter has been painstakingly reviewed and checked for consistent high quality. The result is an authoritative overview which ties the literature together and provides the user with a reliable background information and citation resource.

Comprehensive Chirality Separations And Analysis

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Author : Erick Moran Carreira
language : en
Publisher:
Release Date : 2012

Comprehensive Chirality Separations And Analysis written by Erick Moran Carreira and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Chirality categories.

Advances In The Use Of Liquid Chromatography Mass Spectrometry Lc Ms Instrumentation Developments And Applications

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Author :
language : en
Publisher: Elsevier
Release Date : 2018-01-02

Advances In The Use Of Liquid Chromatography Mass Spectrometry Lc Ms Instrumentation Developments And Applications written by and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-02 with Science categories.

Advances in the Use of Liquid Chromatography Mass Spectrometry (LC-MS): Instrumentation Developments and Application, Volume 79, highlights the most recent LC-MS evolutions through a series of contributions by world renowned scientists that will lead the readers through the most recent innovations in the field and their possible applications. Many authoritative books on LC-MS are already present in market, describing in detail the different interfaces and their principles of operation. This book focuses more on new trends, starting with the innovations of each technique, to the most progressive challenges of LC-MS. - Presents an understanding of the new advancements in LC and MS which are essential for a step forward in LC-MS applications - Provides insight into the state-of-the-art in the currently available LC-MS interfaces and their principle of use - Expounds on the new frontiers in LC-MS and their application potential

Physical Principles Of Chirality In Nmr

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Author : Piotr Garbacz
language : en
Publisher: Royal Society of Chemistry
Release Date : 2024-09-20

Physical Principles Of Chirality In Nmr written by Piotr Garbacz and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-09-20 with Science categories.

How can we study one of the most elusive molecular properties, chirality, using nuclear interactions with the magnetic field that are apparently insensitive to handedness? This book answers this question from the physicochemical point of view by providing a clear, coherent, and comprehensive review of methods used in NMR studies of chirality. Presented arguments based on fundamental physical and chemical laws and in-depth descriptions of new methods utilizing purely physical interactions are mainly addressed to spectroscopists in both academia and industry. The introductory chapters provide the reader with the basics of NMR spectroscopy as a tool for the study of chiral compounds, and those more interested in the methods of chiral discrimination will benefit from the brief description of their common points and reasons why some of them may or may not work. In the following chapters, the book shows rapid progress in a newly emerging field of chirality-sensitive NMR, in particular, a search for effects that give direct information about the absolute configuration of a molecule.

Chiral Analysis

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Author : P.L. Polavarapu
language : en
Publisher: Elsevier
Release Date : 2018-05-30

Chiral Analysis written by P.L. Polavarapu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-05-30 with Science categories.

Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life. - Offers the only book to cover both spectroscopic and separation methods in a single volume - Provides an up-to-date and detailed review of the various techniques available, including new techniques that have emerged since the first edition - Includes contributions from a range of leading experts in the field, now edited by award-winning chirality researcher Prasad Polavarapu

Comprehensive Medicinal Chemistry Ii

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Author : David J Triggle
language : en
Publisher: Elsevier
Release Date : 2006-12-29

Comprehensive Medicinal Chemistry Ii written by David J Triggle and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-12-29 with Medical categories.

The first edition of Comprehensive Medicinal Chemistry was published in 1990 and was very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well. Also available online via ScienceDirect (2006) - featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com. Comprehensively reviews - the strategies, technologies, principles and applications of modern medicinal chemistry Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Chirogenesis In Chemical Science

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Author : Victor Borovkov
language : en
Publisher: World Scientific
Release Date : 2022-12-28

Chirogenesis In Chemical Science written by Victor Borovkov and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-12-28 with Science categories.

Chirogenesis in Chemical Science is an exciting new book that takes readers inside the world of chirality and chirogenesis, guided by Victor Borovkov and Riina Aav, both internationally renowned experts on chirality. Chirality is a fundamental property of the universe and has significance in different organic/inorganic materials, living organisms, and human beings. The basic principle of chirality is existence of an object in two mirror image forms, which are not superimposable. This phenomenon is widely seen in various fields of knowledge including mathematics, astronomy, physics, chemistry, biology and ranging in scale from galaxies to nuclear particles.In chemical science, chirality is generally associated with a single molecule or group of molecules, which symmetry properties belonging to the Cn or Dn point groups with the simplest example of sp3 carbon atom bonded to four different substituents. The dynamic processes of chirality generation, modulation, transfer, amplification, etc. are termed chirogenesis.This is a fast-growing and interdisciplinary field of research, which is widely seen in many natural systems (such as DNA double helix, the secondary alpha-helix structure of proteins, lipid membranes, saccharides, heme proteins, and other biological molecular objects) and various artificial systems. It is of prime importance not only for fundamental science but also for a number of practical applications in such areas as pharmacology and agrochemistry, perfumery and food industry, materials and polymer sciences, enantioselective catalysis and nonlinear optics, nanoscience and nanotechnology, molecular devices and chemical sensors, and others. Therefore, understanding the mechanisms and various influencing factors is of particular significance for smart control and further effective application of chirogenesis in chemistry.

Chirality In Supramolecular Assemblies

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Author : F. Richard Keene
language : en
Publisher: John Wiley & Sons
Release Date : 2017-01-03

Chirality In Supramolecular Assemblies written by F. Richard Keene and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-01-03 with Science categories.

Supramolecular chemistry deals with the organisation of molecules into defined assemblies using non-covalent interactions, including weaker and reversible interactions such as hydrogen bonds, and metal-ligand interactions. The aspect of stereochemistry within such chemical architectures, and in particular chirality, is of special interest as it impacts on considerations of molecular recognition, the development of functional materials, the vexed question of homochirality, nanoscale effects of interactions at interfaces, biocatalysis and enzymatic catalysis, and applications in organic synthesis. Chirality in Supramolecular Assemblies addresses many of these aspects, presenting a broad overview of this important and rapidly developing interdisciplinary field. Topics covered include: Origins of molecular and topological chirality Homochirogenesis Chirality in crystallinity Host-guest behavior Chiral influences in functional materials Chirality in network solids and coordination solids Aspects of chirality at interfaces Chirality in organic assemblies Chirality related to biocatalysis and enzymes in organic synthesis. This book is a valuable reference for researchers in the molecular sciences, materials science and biological science working with chiral supramolecular systems. It provides summaries and special insights by acknowledged international experts in the various fields.

Enantioselective Synthesis Enantiomeric Separations And Chiral Recognition

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Author : Maria Elizabeth Tiritan
language : en
Publisher: MDPI
Release Date : 2020-11-13

Enantioselective Synthesis Enantiomeric Separations And Chiral Recognition written by Maria Elizabeth Tiritan and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-11-13 with Technology & Engineering categories.

This book includes both fundamental studies and applications in a multidisciplinary research field involving a high diversity of chiral compounds, including commercial substances with industrial applications, pharmaceuticals, and new chiral compounds with promising biological activities.

Key Chiral Auxiliary Applications

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Author : Gregory Roos
language : en
Publisher: Academic Press
Release Date : 2014-01-20

Key Chiral Auxiliary Applications written by Gregory Roos and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-01-20 with Science categories.

Key Chiral Auxiliary Applications, Second Edition is a detailed compilation of chiral auxiliary applications organized by type of transformation. Continuing from the most important and relevant auxiliaries described in its predecessor, the three-volume set Compendium of Chiral Auxiliary Applications (2001), as well as advances in the field, the book provides a vital and timely resource for chemists in the field. Each reaction class includes a series of tables and graphical abstracts of real reactions from the literature and patents to enable easy review and comparison of results. This anticipated edition is based on a screening of nearly 40,000 auxiliary reaction applications, with details supplied for the more than 13,000 selected representative entries: synthetic route, reagents, yields, diastereomeric/enantiomeric excesses, and characterization data. Updated and streamlined with more than 60% new material, Key Chiral Auxiliary Applications provides valuable guidance and reliable content for selecting the best auxiliary for a specific asymmetric synthetic transformation. - Provides a comprehensive compilation based on nearly 40,000 diverse applications of chiral auxiliaries for selecting the best synthetic route to optically pure compounds - Contains over 60% new material with 13,000+ auxiliary applications categorized by reaction type, with reaction details and chemical and optical yields in one unique resource