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Compromised Perfusion


Compromised Perfusion
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Compromised Perfusion


Compromised Perfusion
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Author : K. Messmer
language : en
Publisher: S. Karger AG (Switzerland)
Release Date : 1996

Compromised Perfusion written by K. Messmer and has been published by S. Karger AG (Switzerland) this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Medical categories.


Compromised perfusion indicates the inability of the cardiovascular system to sustain the normal distribution of blood flow within the entire body and can be defined as a reduction of perfusion pressure leading to the exclusion of single capillaries or groups of capillaries. Occurring in patients subjected to shock, trauma, extensive surgery and organ transplantation, it reduces the surface area available for exchange of nutrients and metabolites with the consequence of tissue hypoxia and accumulation of waste products. To counteract compromised perfusion hypertonic/hyperoncotic saline/dextran solutions are used efficiently. This book presents an overview of the most recent findings from studies investigating compromised perfusion. The selected contributions discuss the mechanistic effects and side effects of small volume resuscitation, as well as specific effects of dextran in the field of organ conservation and post-ischemic leukocyte/endothelium interaction. Furthermore, specific aspects of the biology and pathophysiology of microvascular endothelium are considered. Providing a critical review of recent advances, this volume serves as an excellent source of information for all those interested in both clinical and experimental microcirculation research.



Inflammation And The Microcirculation


Inflammation And The Microcirculation
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Author : D. Neil Granger
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2010

Inflammation And The Microcirculation written by D. Neil Granger and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Medical categories.


The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References



Regulation Of Coronary Blood Flow


Regulation Of Coronary Blood Flow
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Author : Michitoshi Inoue
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-09

Regulation Of Coronary Blood Flow written by Michitoshi Inoue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-09 with Medical categories.


Research centering on blood flow in the heart continues to hold an important position, especially since a better understanding of the subject may help reduce the incidence of coronary arterial disease and heart attacks. This book summarizes recent advances in the field; it is the product of fruitful cooperation among international scientists who met in Japan in May, 1990 to discuss the regulation of coronary blood flow.



Paramedic Principles And Practice In The Uk E Book


Paramedic Principles And Practice In The Uk E Book
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Author : Aidan Ward
language : en
Publisher: Elsevier Health Sciences
Release Date : 2023-04-13

Paramedic Principles And Practice In The Uk E Book written by Aidan Ward and has been published by Elsevier Health Sciences this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-04-13 with Medical categories.


Paramedic Principles and Practice in the UK is a key textbook designed to support paramedicine students in this country throughout their studies. The volume takes a practical approach, with case histories covering a broad range of clinical presentations and treatments, all incorporating a patient-centric perspective that acknowledges the longer patient journey. This must-have textbook will not only arm readers with technical knowledge and expertise, but also with the non-technical principles of the profession, developing future paramedics who are able to provide a safe and effective management plan in the out-of-hospital environment. Aligned to UK paramedicine curricula More than 40 detailed case studies covering essential pathologies most commonly seen by UK paramedics, as well as less typical scenarios Evidence-based clinical decision-making models to support paramedics in practice Essential physiological concepts to help readers bridge the gap from principles to practice Focus on the wellbeing of both the patient and the paramedic Useful appendices including medications commonly encountered in paramedic settings



Cardiac Perfusion And Pumping Engineering


Cardiac Perfusion And Pumping Engineering
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Author : Dhanjoo N Ghista
language : en
Publisher: World Scientific
Release Date : 2007-07-24

Cardiac Perfusion And Pumping Engineering written by Dhanjoo N Ghista and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-24 with Medical categories.


For the first time, this invaluable book shows how cardiac perfusion and pumping can be quantified and correlated. Self-contained and unified in presentation, the explanations in the compendium are detailed enough to capture the reader's curiosity and complete enough to provide the background material to explore further into the subject.Mathematically rigorous and clinically oriented, the book is a major resource for biomedical engineers, cardiologists, cardiac surgeons and clinicians. For students, it is an ideal textbook for senior-level courses in cardiovascular engineering.



Interventional Treatment Of Wounds


Interventional Treatment Of Wounds
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Author : Dennis P. Orgill
language : en
Publisher: Springer
Release Date : 2018-01-12

Interventional Treatment Of Wounds written by Dennis P. Orgill and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-01-12 with Medical categories.


Our aging population, combined with an increase incidence of both diabetes and obesity, has fueled the need for better care of acute and chronic wounds associated with these diseases. Interventional Wound Healing focuses on what modern surgery can do to accelerate the healing of such wounds. Utilizing case studies alongside background and in-depth analysis for each technique with color images and videos, this book is intended to guide the reader in surgical and non-surgical procedures to assist with wound closure. Edited by the medical director of the Brigham and Women's Hospital Wound Care Center, Interventional Wound Healing takes the plastic surgeon's point of view on wound care and various surgical and non-surgical interventional treatments. Where the typical wound care book addresses bandaging and dressing of various surface wounds, Interventional Wound Healing delves into the surgical and interventional procedures that can effectively treat both acute and chronic wounds. Written for wound care professional including physicians, podiatrists, nurses, residents and students this book features three distinct sections covering surgical methods and techniques, amputation, and interventional techniques, paying special attention to skin grafts, flaps, and substitutions, as well as arterial and venous interventions.



Investigation Of New Electro Optical Techniques For Monitoring Patients With Compromised Peripheral Perfusion In Anaesthesia


Investigation Of New Electro Optical Techniques For Monitoring Patients With Compromised Peripheral Perfusion In Anaesthesia
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Author : Panayiotis A. Kyriacou
language : en
Publisher:
Release Date : 2001

Investigation Of New Electro Optical Techniques For Monitoring Patients With Compromised Peripheral Perfusion In Anaesthesia written by Panayiotis A. Kyriacou and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with categories.




The Cerebral Circulation


The Cerebral Circulation
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Author : Marilyn J. Cipolla
language : en
Publisher: Biota Publishing
Release Date : 2016-07-28

The Cerebral Circulation written by Marilyn J. Cipolla and has been published by Biota Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-07-28 with Medical categories.


This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.



Catheter Based Magnetic Resonance Compatible Perfusion Probe


Catheter Based Magnetic Resonance Compatible Perfusion Probe
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Author : Cara Lynne Toretta
language : en
Publisher:
Release Date : 2007

Catheter Based Magnetic Resonance Compatible Perfusion Probe written by Cara Lynne Toretta and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007 with categories.


Neurosurgeons are using a thermal based technique to quantify brain perfusion. The thermal diffusion probe (TDP) technology measures perfusion in a relatively small volume of brain tissue. The neurosurgeon chooses the specific brain location and probe placement based on their clinical concern. When an early indication of compromised perfusion is detected by the TDP, it is generally necessary to confirm the local, absolute perfusion measurement taken with the TDP, with magnetic resonance (MR) perfusion imaging. MR perfusion imaging provides an excellent, but relative, global assessment of compromised tissue perfusion. Due to the many clinical and diagnostic benefits of real-time, absolute quantification of blood flow acquired by the TDP, there has been increased interest in having the TDP MR compatible. This thesis considers what it would take to render the TDP MR compatible in both the active and passive modes. The analysis considers effects of the EM field on the probe, and the probe on the MR image. The presence of cardiac and respiratory induced brain motion has been shown to provide an artifact in TDP-perfusion data. Consideration is given to ways in which to minimize this motion induced perfusion artifact.



Practical Issues In Anesthesia And Intensive Care


Practical Issues In Anesthesia And Intensive Care
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Author : Biagio Allaria
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-03-15

Practical Issues In Anesthesia And Intensive Care written by Biagio Allaria and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-03-15 with Medical categories.


The contents of this book are a selection taken from materials that have been developed during the preparation of continuing education courses (distance learning), whose scientific advisor is the volume editor, Professor Allaria, and that have never previously been published. The topics considered are wide ranging; particular attention is devoted to general topics of importance to the practitioner, but specific controversial issues, such as the role of goal-directed hemodynamic therapy, are also addressed. All of the authors are recognized experts on the subjects they discuss. The book is part of a wider project that aims to provide updated information each year not only in anesthesiology but also in other fields, including cardiology, ophthalmology, and nephrology.