Computational And Experimental Approaches On Soft Tissues Biomechanics And Mechanobiology

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Computational And Experimental Approaches On Soft Tissues Biomechanics And Mechanobiology
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Author : Lei Fan
language : en
Publisher: Frontiers Media SA
Release Date : 2025-06-19
Computational And Experimental Approaches On Soft Tissues Biomechanics And Mechanobiology written by Lei Fan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2025-06-19 with Technology & Engineering categories.
Soft tissues, which encompass all organs of the body, such as the brain, muscles, and tendons, play a crucial role in maintaining the normal function in the human body. Understanding the biomechanics and mechanobiology of these tissues by integrating computational and experimental approaches is essential for advancing the clinical treatments, medical device development and overall healthcare. This topic outlines multidisciplinary research on understanding soft tissues’ biomechanics and mechanobiology under various physiological and pathological conditions. The proposed topic aims to combine experimental and computational methods to gain insights into the complex mechanical behaviors of soft tissues. To achieve this goal, this Research Topic will focus on some specific objectives like developing novel computational models to elucidate soft tissue behavior and quantifying the effects of diseases, characterizing soft tissue properties by advancing experimental techniques, such as tissue testing, imaging and microscale analysis. This will help in characterizing the mechanical properties and structural behavior of various soft tissues under both physiological and pathological conditions. We welcome the studies that investigates mechanobiological processes such as tissue remodeling, adaption, and injury, by integrating computational models with experimental data to gain insights into mechanical behavior. The studies that apply the findings from this research to improve clinical applications, such as subject-specific treatment, development of medical devices and regenerative medicine. This topic will also cover the interdisciplinary research by integrating biomechanics, biology, engineering, clinical studies, and imaging techniques. • Computational modeling development • Machine learning applications • Experimental characterization • Imaging processing techniques • Mechanobiological processes • Disease mechanisms • Application in clinical treatments and medical devices
Biomechanics
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Author : Manuel Doblare
language : en
Publisher: EOLSS Publications
Release Date : 2015-12-30
Biomechanics written by Manuel Doblare and has been published by EOLSS Publications this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-12-30 with categories.
Biomechanics is a component of Encyclopedia of Physical Sciences, Engineering and Technology Resources in the global Encyclopedia of Life Support Systems (EOLSS), which is an integrated compendium of twenty one Encyclopedias. The enormous progress in the field of health sciences that has been achieved in the 19th and 20th centuries would have not been possible without the enabling interaction and support of sophisticated technologies that progressively gave rise to a new interdisciplinary field named alternatively as bioengineering or biomedical engineering. Although both terms are synonymous, the latter is less general since it limits the field of application to medicine and clinical practice, while the former covers semantically the whole field of interaction between life sciences and engineering, thus including also applications in biology, biochemistry or the many '-omics'. We use in this book the second, with more general meaning, recalling the very important relation between fundamental science and engineering. And this also recognizes the tremendous economic and social impacts of direct application of engineering in medicine that maintains the health industry as one with the fastest growth in the world economy. Biomechanics, in particular, aims to explain and predict the mechanics of the different components of living beings, from molecules to organisms as well as to design, manufacture and use of any artificial device that interacts with the mechanics of living beings. It helps, therefore, to understand how living systems move, to characterize the interaction between forces and deformation along all spatial scales, to analyze the interaction between structural behavior and microstructure, with the very important particularity of dealing with adaptive systems, able to adapt their internal structure, size and geometry to the particular mechanical environment in which they develop their activity, to understand and predict alterations in the mechanical function due to injuries, diseases or pathologies and, finally, to propose methods of artificial intervention for functional diagnosis or recovery. Biomechanics is today a very highly interdisciplinary subject that attracts the attention of engineers, mathematicians, physicists, chemists, material specialists, biologists, medical doctors, etc. They work in many different topics from a purely scientific objective to industrial applications and with an increasing arsenal of sophisticated modeling and experimental tools but always with the final objectives of better understanding the fundamentals of life and improve the quality of life of human beings. One purpose in this volume has been to present an overview of some of these many possible subjects in a self-contained way for a general audience. This volume is aimed at the following major target audiences: University and College Students, Educators, Professional Practitioners, and Research Personnel.
Advances In Biomechanics And Tissue Regeneration
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Author : Mohamed H. Doweidar
language : en
Publisher: Academic Press
Release Date : 2019-08-13
Advances In Biomechanics And Tissue Regeneration written by Mohamed H. Doweidar and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-13 with Science categories.
Advances in Biomechanics and Tissue Regeneration covers a wide range of recent development and advances in the fields of biomechanics and tissue regeneration. It includes computational simulation, soft tissues, microfluidics, the cardiovascular system, experimental methods in biomechanics, mechanobiology and tissue regeneration. The state-of-the-art, theories and application are presented, making this book ideal for anyone who is deciding which direction to take their future research in this field. In addition, it is ideal for everyone who is exploring new fields or currently working on an interdisciplinary project in tissue biomechanics. - Combines new trends in biomechanical modelling and tissue regeneration - Offers a broad scope, covering the entire field of tissue biomechanics - Contains perspectives from engineering, medicine and biology, thus giving a holistic view of the field
Experimental And Applied Mechanics Volume 6
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Author : Tom Proulx
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-05-27
Experimental And Applied Mechanics Volume 6 written by Tom Proulx and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-05-27 with Technology & Engineering categories.
Experimental and Applied Mechanics represents one of eight volumes of technical papers presented at the Society for Experimental Mechanics Annual Conference on Experimental and Applied Mechanics, held at Uncasville, Connecticut, June 13-16, 2011. The full set of proceedings also includes volumes on Dynamic Behavior of Materials, Mechanics of Biological Systems and Materials, Challenges in Mechanics of Time-Dependent Materials and Processes in Conventional and Multifunctional Materials, MEMS and Nanotechnology; Optical Measurements, Modeling and, Metrology; Experimental and Applied Mechanics, Thermomechanics and Infra-Red Imaging, and Engineering Applications of Residual Stress.
Orthopaedic Biomechanics
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Author : Beth A. Winkelstein
language : en
Publisher: CRC Press
Release Date : 2012-12-18
Orthopaedic Biomechanics written by Beth A. Winkelstein and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-18 with Medical categories.
Given the strong current attention of orthopaedic, biomechanical, and biomedical engineering research on translational capabilities for the diagnosis, prevention, and treatment of clinical disease states, the need for reviews of the state-of-art and current needs in orthopaedics is very timely. Orthopaedic Biomechanics provides an in-depth review of the current knowledge of orthopaedic biomechanics across all tissues in the musculoskeletal system, at all size scales, and with direct relevance to engineering and clinical applications. Discussing the relationship between mechanical loading, function, and biological performance, it first reviews basic structure-function relationships for most major orthopedic tissue types followed by the most-relevant structures of the body. It then addresses multiscale modeling and biologic considerations. It concludes with a look at applications of biomechanics, focusing on recent advances in theory, technology and applied engineering approaches. With contributions from leaders in the field, the book presents state-of-the-art findings, techniques, and perspectives. Much of orthopaedic, biomechanical, and biomedical engineering research is directed at the translational capabilities for the "real world". Addressing this from the perspective of diagnostics, prevention, and treatment in orthopaedic biomechanics, the book supplies novel perspectives for the interdisciplinary approaches required to translate orthopaedic biomechanics to today’s real world.
Reduced Order Models For The Biomechanics Of Living Organs
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Author : Francisco Chinesta
language : en
Publisher: Elsevier
Release Date : 2023-05-25
Reduced Order Models For The Biomechanics Of Living Organs written by Francisco Chinesta and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-05-25 with Technology & Engineering categories.
Reduced Order Models for the Biomechanics of Living Organs, a new volume in the Biomechanics of Living Organisms series, provides a comprehensive overview of the state-of-the-art in biomechanical computations using reduced order models, along with a deeper understanding of the associated reduction algorithms that will face students, researchers, clinicians and industrial partners in the future. The book gathers perspectives from key opinion scientists who describe and detail their approaches, methodologies and findings. It is the first to synthesize complementary advances in Biomechanical modelling of living organs using reduced order techniques in the design of medical devices and clinical interventions, including surgical procedures. This book provides an opportunity for students, researchers, clinicians and engineers to study the main topics related to biomechanics and reduced models in a single reference, with this volume summarizing all biomechanical aspects of each living organ in one comprehensive reference. - Introduces the fundamental aspects of reduced order models - Presents the main computational studies in the field of solid and fluid biomechanical modeling of living organs - Explores the use of reduced order models in the fields of biomechanical electrophysiology, tissue growth and prosthetic designs
Material Parameter Identification And Inverse Problems In Soft Tissue Biomechanics
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Author : Stéphane Avril
language : en
Publisher: Springer
Release Date : 2016-10-12
Material Parameter Identification And Inverse Problems In Soft Tissue Biomechanics written by Stéphane Avril and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-10-12 with Technology & Engineering categories.
The articles in this book review hybrid experimental-computational methods applied to soft tissues which have been developed by worldwide specialists in the field. People developing computational models of soft tissues and organs will find solutions for calibrating the material parameters of their models; people performing tests on soft tissues will learn what to extract from the data and how to use these data for their models and people worried about the complexity of the biomechanical behavior of soft tissues will find relevant approaches to address this complexity.
Solid Bio Mechanics Challenges Of The Next Decade
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Author : Gerhard Sommer
language : en
Publisher: Springer Nature
Release Date : 2022-06-14
Solid Bio Mechanics Challenges Of The Next Decade written by Gerhard Sommer and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-06-14 with Technology & Engineering categories.
This book offers a comprehensive and timely overview of the latest developments in the field of biomechanics and extensive knowledge of tissue structure, function, and modeling. Gathering chapters written by authoritative scientists, it reports on a range of continuum and computational models of solids, and related experimental works, for biomechanical applications. It discusses cutting-edge advances such as constitutive modeling and computational simulation of biological tissues and organs under physiological and pathological conditions, and their mechanical characterization. It covers innovative studies on arteries, heart, valvular tissue, and thrombus, brain tumor, muscle, liver, kidney, and stomach, among others. Written in honor of Professor Gerhard A. Holzapfel, the book provides specialized readers with a thorough and timely overview of different types of modeling in biomechanics, and current knowledge about biological structures and function.
Modeling Biomaterials
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Author : Josef Málek
language : en
Publisher: Springer Nature
Release Date : 2022-01-21
Modeling Biomaterials written by Josef Málek and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-21 with Mathematics categories.
The investigation of the role of mechanical and mechano-chemical interactions in cellular processes and tissue development is a rapidly growing research field in the life sciences and in biomedical engineering. Quantitative understanding of this important area in the study of biological systems requires the development of adequate mathematical models for the simulation of the evolution of these systems in space and time. Since expertise in various fields is necessary, this calls for a multidisciplinary approach. This edited volume connects basic physical, biological, and physiological concepts to methods for the mathematical modeling of various materials by pursuing a multiscale approach, from subcellular to organ and system level. Written by active researchers, each chapter provides a detailed introduction to a given field, illustrates various approaches to creating models, and explores recent advances and future research perspectives. Topics covered include molecular dynamics simulations of lipid membranes, phenomenological continuum mechanics of tissue growth, and translational cardiovascular modeling. Modeling Biomaterials will be a valuable resource for both non-specialists and experienced researchers from various domains of science, such as applied mathematics, biophysics, computational physiology, and medicine.
Numerical Methods And Advanced Simulation In Biomechanics And Biological Processes
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Author : Miguel Cerrolaza
language : en
Publisher: Academic Press
Release Date : 2017-12-28
Numerical Methods And Advanced Simulation In Biomechanics And Biological Processes written by Miguel Cerrolaza and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-12-28 with Technology & Engineering categories.
Numerical Methods and Advanced Simulation in Biomechanics and Biological Processes covers new and exciting modeling methods to help bioengineers tackle problems for which the Finite Element Method is not appropriate. The book covers a wide range of important subjects in the field of numerical methods applied to biomechanics, including bone biomechanics, tissue and cell mechanics, 3D printing, computer assisted surgery and fluid dynamics. Modeling strategies, technology and approaches are continuously evolving as the knowledge of biological processes increases. Both theory and applications are covered, making this an ideal book for researchers, students and R&D professionals. - Provides non-conventional analysis methods for modeling - Covers the Discrete Element Method (DEM), Particle Methods (PM), MessLess and MeshFree Methods (MLMF), Agent-Based Methods (ABM), Lattice-Boltzmann Methods (LBM) and Boundary Integral Methods (BIM) - Includes contributions from several world renowned experts in their fields - Compares pros and cons of each method to help you decide which method is most applicable to solving specific problems