Computational Intelligence In Protein Ligand Interaction Analysis

DOWNLOAD

Download Computational Intelligence In Protein Ligand Interaction Analysis PDF/ePub or read online books in Mobi eBooks. Click Download or Read Online button to get Computational Intelligence In Protein Ligand Interaction Analysis book now. This website allows unlimited access to, at the time of writing, more than 1.5 million titles, including hundreds of thousands of titles in various foreign languages. If the content not found or just blank you must refresh this page

Computational Intelligence In Protein Ligand Interaction Analysis

DOWNLOAD
Author : Bing Wang
language : en
Publisher: Academic Press
Release Date : 2024-03-22

Computational Intelligence In Protein Ligand Interaction Analysis written by Bing Wang and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-22 with Science categories.

Computational Intelligence in Protein-Ligand Interaction Analysis presents computational techniques for predicting protein-ligand interactions, recognizing protein interaction sites, and identifying protein drug targets. The book emphasizes novel approaches to protein-ligand interactions, including machine learning and deep learning, presenting a state-of-the-art suite of skills for researchers. The volume represents a resource for scientists, detailing the fundamentals of computational methods, showing how to use computational algorithms to study protein interaction data, and giving scientific explanations for biological data through computational intelligence. Fourteen chapters offer a comprehensive guide to protein interaction data and computational intelligence methods for protein-ligand interactions. Presents a guide to computational techniques for protein-ligand interaction analysis Guides researchers in developing advanced computational intelligence methods for the protein-ligand problem Identifies appropriate computational tools for various problems Demonstrates the use of advanced techniques such as vector machine, neural networks, and machine learning Offers the computational, mathematical and statistical skills researchers need

Computational Intelligence In Bioinformatics

DOWNLOAD
Author : Gary B. Fogel
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-10

Computational Intelligence In Bioinformatics written by Gary B. Fogel and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-10 with Computers categories.

Combining biology, computer science, mathematics, and statistics, the field of bioinformatics has become a hot new discipline with profound impacts on all aspects of biology and industrial application. Now, Computational Intelligence in Bioinformatics offers an introduction to the topic, covering the most relevant and popular CI methods, while also encouraging the implementation of these methods to readers' research.

Protein Interactions Computational Methods Analysis And Applications

DOWNLOAD
Author : M Michael Gromiha
language : en
Publisher: World Scientific
Release Date : 2020-03-05

Protein Interactions Computational Methods Analysis And Applications written by M Michael Gromiha and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-03-05 with Science categories.

This book is indexed in Chemical Abstracts ServiceThe interactions of proteins with other molecules are important in many cellular activities. Investigations have been carried out to understand the recognition mechanism, identify the binding sites, analyze the the binding affinity of complexes, and study the influence of mutations on diseases. Protein interactions are also crucial in structure-based drug design.This book covers computational analysis of protein-protein, protein-nucleic acid and protein-ligand interactions and their applications. It provides up-to-date information and the latest developments from experts in the field, using illustrations to explain the key concepts and applications. This volume can serve as a single source on comparative studies of proteins interacting with proteins/DNAs/RNAs/carbohydrates and small molecules.

Computational Intelligence In Medical Informatics

DOWNLOAD
Author : Naresh Babu Muppalaneni
language : en
Publisher: Springer
Release Date : 2014-11-06

Computational Intelligence In Medical Informatics written by Naresh Babu Muppalaneni and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-06 with Technology & Engineering categories.

This Brief highlights Informatics and related techniques to Computer Science Professionals, Engineers, Medical Doctors, Bioinformatics researchers and other interdisciplinary researchers. Chapters include the Bioinformatics of Diabetes and several computational algorithms and statistical analysis approach to effectively study the disorders and possible causes along with medical applications.

Computational Intelligence Methods For Bioinformatics And Biostatistics

DOWNLOAD
Author : Enrico Formenti
language : en
Publisher: Springer
Release Date : 2014-07-15

Computational Intelligence Methods For Bioinformatics And Biostatistics written by Enrico Formenti and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-15 with Computers categories.

This book constitutes the thoroughly refereed post-conference proceedings of the 10th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2013, held in Nice, France in June 2013. The 19 revised full papers presented were carefully reviewed and selected from 35 submissions. The papers are organized in topical sections on bioinformatics, biostatistics, knowledge based medicine, and data integration and analysis in omic-science.

Computational Analyses Of Protein Ligand Interactions

DOWNLOAD
Author :
language : en
Publisher:
Release Date : 2010

Computational Analyses Of Protein Ligand Interactions written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with categories.

Marvels Of Artificial And Computational Intelligence In Life Sciences

DOWNLOAD
Author : Thirunavukkarasu Sivaraman
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-09-20

Marvels Of Artificial And Computational Intelligence In Life Sciences written by Thirunavukkarasu Sivaraman and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-09-20 with Computers categories.

Marvels of Artificial and Computational Intelligence in Life Sciences is a primer for scholars and students who are interested in the applications of artificial intelligence (AI and computational intelligence (CI) in life sciences and other industries. The book consists of 16 chapters (9 of which focus on AI and 7 which showcase the benefits of CI approaches to solve specific problems). Chapters are edited by subject experts who describe the roles and applications of AI and CI in different parts of our lives in a concise and lucid manner. The book covers the following key themes: AI Revolution in Healthcare and Drug Discovery: AI's Impact on Biology and Energy Management AI and CI in Physical Sciences and Predictive Modeling Computational Biology The editors have compiled a good blend of topics in applied science and engineering to give readers a clear understanding of the multidisciplinary nature of the two facets of computing. Each chapter includes references for advanced readers.

Protein Ligand Interactions

DOWNLOAD
Author : Hans-Joachim Böhm
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06

Protein Ligand Interactions written by Hans-Joachim Böhm and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.

The lock-and-key principle formulated by Emil Fischer as early as the end of the 19th century has still not lost any of its significance for the life sciences. The basic aspects of ligand-protein interaction may be summarized under the term 'molecular recognition' and concern the specificity as well as stability of ligand binding. Molecular recognition is thus a central topic in the development of active substances, since stability and specificity determine whether a substance can be used as a drug. Nowadays, computer-aided prediction and intelligent molecular design make a large contribution to the constant search for, e. g., improved enzyme inhibitors, and new concepts such as that of pharmacophores are being developed. An up-to-date presentation of an eternally young topic, this book is an indispensable information source for chemists, biochemists and pharmacologists dealing with the binding of ligands to proteins.

Protein Ligand Interactions

DOWNLOAD
Author : Holger Gohlke
language : en
Publisher: John Wiley & Sons
Release Date : 2012-05-21

Protein Ligand Interactions written by Holger Gohlke and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-21 with Medical categories.

Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interactions, followed by a comparison of key experimental methods (calorimetry, surface plasmon resonance, NMR) used in generating interaction data. The second half of the book is devoted to insilico methods of modeling and predicting molecular recognition and binding, ranging from first principles-based to approximate ones. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. With the content relevant for all drug classes and therapeutic fields, this is an inspiring and often-consulted guide to the complexity of protein-ligand interaction modeling and analysis for both novices and experts.

Computational Drug Discovery

DOWNLOAD
Author : Vasanthanathan Poongavanam
language : en
Publisher: John Wiley & Sons
Release Date : 2024-01-19

Computational Drug Discovery written by Vasanthanathan Poongavanam and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-01-19 with Science categories.

Computational Drug Discovery A comprehensive resource that explains a wide array of computational technologies and methods driving innovation in drug discovery Computational Drug Discovery: Methods and Applications (2 volume set) covers a wide range of cutting-edge computational technologies and computational chemistry methods that are transforming drug discovery. The book delves into recent advances, particularly focusing on artificial intelligence (AI) and its application for protein structure prediction, AI-enabled virtual screening, and generative modeling for compound design. Additionally, it covers key technological advancements in computing such as quantum and cloud computing that are driving innovations in drug discovery. Furthermore, dedicated chapters that addresses the recent trends in the field of computer aided drug design, including ultra-large-scale virtual screening for hit identification, computational strategies for designing new therapeutic modalities like PROTACs and covalent inhibitors that target residues beyond cysteine are also presented. To offer the most up-to-date information on computational methods utilized in computational drug discovery, it covers chapters highlighting the use of molecular dynamics and other related methods, application of QM and QM/MM methods in computational drug design, and techniques for navigating and visualizing the chemical space, as well as leveraging big data to drive drug discovery efforts. The book is thoughtfully organized into eight thematic sections, each focusing on a specific computational method or technology applied to drug discovery. Authored by renowned experts from academia, pharmaceutical industry, and major drug discovery software providers, it offers an overview of the latest advances in computational drug discovery. Key topics covered in the book include: Application of molecular dynamics simulations and related approaches in drug discovery The application of QM, hybrid approaches such as QM/MM, and fragment molecular orbital framework for understanding protein-ligand interactions Adoption of artificial intelligence in pre-clinical drug discovery, encompassing protein structure prediction, generative modeling for de novo design, and virtual screening. Techniques for navigating and visualizing the chemical space, along with harnessing big data to drive drug discovery efforts. Methods for performing ultra-large-scale virtual screening for hit identification. Computational strategies for designing new therapeutic models, including PROTACs and molecular glues. In silico ADMET approaches for predicting a variety of pharmacokinetic and physicochemical endpoints. The role of computing technologies like quantum computing and cloud computing in accelerating drug discovery This book will provide readers an overview of the latest advancements in computational drug discovery and serve as a valuable resource for professionals engaged in drug discovery.