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Computational Methods For Processing And Analysis Of Biological Pathways


Computational Methods For Processing And Analysis Of Biological Pathways
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Computational Methods For Processing And Analysis Of Biological Pathways


Computational Methods For Processing And Analysis Of Biological Pathways
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Author : Anastasios Bezerianos
language : en
Publisher: Springer
Release Date : 2017-03-09

Computational Methods For Processing And Analysis Of Biological Pathways written by Anastasios Bezerianos and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-03-09 with Computers categories.


This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.



Pathway Analysis For Drug Discovery


Pathway Analysis For Drug Discovery
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Author : Anton Yuryev
language : en
Publisher: John Wiley & Sons
Release Date : 2008-09-17

Pathway Analysis For Drug Discovery written by Anton Yuryev and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-09-17 with Science categories.


This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.



Computational Methods In Systems Biology


Computational Methods In Systems Biology
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Author : Corrado Priami
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-10-11

Computational Methods In Systems Biology written by Corrado Priami and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-11 with Computers categories.


This book constitutes the refereed proceedings of the International Conference on Computational Methods in Systems Biology, CMSB 2006, held in Trento, Italy, in October 2006. The 22 fully revised papers presented together with 2 invited talks were carefully reviewed and selected from 68 submissions. The papers present a variety of techniques from computer sciences, such as language design, concurrency theory, software engineering, and formal methods.



Computational Methods With Applications In Bioinformatics Analysis


Computational Methods With Applications In Bioinformatics Analysis
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Author : Tsai Jeffrey J P
language : en
Publisher: World Scientific
Release Date : 2017-06-09

Computational Methods With Applications In Bioinformatics Analysis written by Tsai Jeffrey J P and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-09 with Computers categories.


This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms. The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics. The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.



Computational Methods In Systems Biology


Computational Methods In Systems Biology
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Author : Vincent Danos
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-03-24

Computational Methods In Systems Biology written by Vincent Danos and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-24 with Computers categories.


The Computational Methods in Systems Biology (CMSB) workshop series was established in 2003 by Corrado Priami. The purpose of the workshop series is to help catalyze the convergence between computer scientists interested in language design, concurrency theory, software engineering or program verification, and physicists, mathematicians and biologists interested in the systems-level understanding of cellular processes. Systems biology was perceived as being increasingly in search of sophisticated modeling frameworks whether for representing and processing syst- level dynamics or for model analysis, comparison and refinement. One has here a clear-cut case of a must-explore field of application for the formal methods developed in computer science in the last decade. This proceedings consists of papers from the CMSB 2003 workshop. A good third of the 24 papers published here have a distinct formal methods origin; we take this as a confirmation that a synergy is building that will help solidify CMSB as a forum for cross-community exchange, thereby opening new theoretical avenues and making the field less of a potential application and more of a real one. Publication in Springer's new Lecture Notes in Bioinformatics (LNBI) offers particular visibility and impact, which we gratefully acknowledge. Our keynote speakers, Alfonso Valencia and Trey Ideker, gave challenging and somewhat humbling lectures: they made it clear that strong applications to systems biology are still some way ahead. We thank them all the more for accepting the invitation to speak and for the clarity and excitement they brought to the conference.



Computational Methods In Systems Biology


Computational Methods In Systems Biology
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Author : Corrado Priami
language : en
Publisher: Springer
Release Date : 2003-07-01

Computational Methods In Systems Biology written by Corrado Priami and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-07-01 with Science categories.


This book constitutes the refereed proceedings of the International Workshop on Computational Methods in Systems Biology, CMSB 2003, held in Rovereto, Italy, in February 2003. The 11 revised full papers presented together with 2 invited papers, 7 position papers, and 11 abstracts were carefully reviewed and selected from 30 submissions. Among the topics addressed are modeling languages for systems biology, concurrency in biological systems, constraint programming, logical methods in systems biology, formal methods for the analysis of biomolecular systems, quantitative analysis of biomolecular systems, and simulation and modeling techniques for systems biology.



Computational Methods In Systems Biology


Computational Methods In Systems Biology
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Author : Muffy Calder
language : en
Publisher: Springer
Release Date : 2007-09-04

Computational Methods In Systems Biology written by Muffy Calder and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-09-04 with Computers categories.


This book constitutes the refereed proceedings of the International Conference on Computational Methods in Systems Biology, CMSB 2007, held in Edinburgh, Scotland, September 2007. The 16 revised full papers presented present a variety of techniques from computer science, such as language design, concurrency theory, software engineering, and formal methods, for biologists, physicists, and mathematicians interested in the systems-level understanding of cellular processes.



Computational Analysis Of Biochemical Systems


Computational Analysis Of Biochemical Systems
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Author : Eberhard O. Voit
language : en
Publisher: Cambridge University Press
Release Date : 2000-09-04

Computational Analysis Of Biochemical Systems written by Eberhard O. Voit and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-09-04 with Medical categories.


Teaches the use of modern computational methods for the analysis of biomedical systems using case studies and accompanying software.



Computational Methods For Next Generation Sequencing Data Analysis


Computational Methods For Next Generation Sequencing Data Analysis
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Author : Ion Mandoiu
language : en
Publisher: John Wiley & Sons
Release Date : 2016-09-12

Computational Methods For Next Generation Sequencing Data Analysis written by Ion Mandoiu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-12 with Computers categories.


Introduces readers to core algorithmic techniques for next-generation sequencing (NGS) data analysis and discusses a wide range of computational techniques and applications This book provides an in-depth survey of some of the recent developments in NGS and discusses mathematical and computational challenges in various application areas of NGS technologies. The 18 chapters featured in this book have been authored by bioinformatics experts and represent the latest work in leading labs actively contributing to the fast-growing field of NGS. The book is divided into four parts: Part I focuses on computing and experimental infrastructure for NGS analysis, including chapters on cloud computing, modular pipelines for metabolic pathway reconstruction, pooling strategies for massive viral sequencing, and high-fidelity sequencing protocols. Part II concentrates on analysis of DNA sequencing data, covering the classic scaffolding problem, detection of genomic variants, including insertions and deletions, and analysis of DNA methylation sequencing data. Part III is devoted to analysis of RNA-seq data. This part discusses algorithms and compares software tools for transcriptome assembly along with methods for detection of alternative splicing and tools for transcriptome quantification and differential expression analysis. Part IV explores computational tools for NGS applications in microbiomics, including a discussion on error correction of NGS reads from viral populations, methods for viral quasispecies reconstruction, and a survey of state-of-the-art methods and future trends in microbiome analysis. Computational Methods for Next Generation Sequencing Data Analysis: Reviews computational techniques such as new combinatorial optimization methods, data structures, high performance computing, machine learning, and inference algorithms Discusses the mathematical and computational challenges in NGS technologies Covers NGS error correction, de novo genome transcriptome assembly, variant detection from NGS reads, and more This text is a reference for biomedical professionals interested in expanding their knowledge of computational techniques for NGS data analysis. The book is also useful for graduate and post-graduate students in bioinformatics.



Computational Methods In Systems Biology


Computational Methods In Systems Biology
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Author : David Gilbert
language : en
Publisher: Springer
Release Date : 2012-09-28

Computational Methods In Systems Biology written by David Gilbert and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-28 with Computers categories.


This book constitutes the thoroughly refereed conference proceedings of the 10th International Conference on Computational Methods in Systems Biology, CMSB 2012, held in London, UK, during October 3-5, 2012. The 17 revised full papers and 8 flash posters presented together with the summaries of 3 invited papers were carefully reviewed and selected from 62 submissions. The papers cover the analysis of biological systems, networks, and data ranging from intercellular to multiscale. Topics included high-performance computing, and for the first time papers on synthetic biology.