Computational Modelling Of The Brain
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Computational Modelling Of The Brain
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Author : Michele Giugliano
language : en
Publisher: Springer Nature
Release Date : 2022-04-26
Computational Modelling Of The Brain written by Michele Giugliano and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-26 with Medical categories.
This volume offers an up-to-date overview of essential concepts and modern approaches to computational modelling, including the use of experimental techniques related to or directly inspired by them. The book introduces, at increasing levels of complexity and with the non-specialist in mind, state-of-the-art topics ranging from single-cell and molecular descriptions to circuits and networks. Four major themes are covered, including subcellular modelling of ion channels and signalling pathways at the molecular level, single-cell modelling at different levels of spatial complexity, network modelling from local microcircuits to large-scale simulations of entire brain areas and practical examples. Each chapter presents a systematic overview of a specific topic and provides the reader with the fundamental tools needed to understand the computational modelling of neural dynamics. This book is aimed at experimenters and graduate students with little or no prior knowledge of modelling who are interested in learning about computational models from the single molecule to the inter-areal communication of brain structures. The book will appeal to computational neuroscientists, engineers, physicists and mathematicians interested in contributing to the field of neuroscience. Chapters 6, 10 and 11 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Computational Models Of Brain And Behavior
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Author : Ahmed A. Moustafa
language : en
Publisher: John Wiley & Sons
Release Date : 2017-11-13
Computational Models Of Brain And Behavior written by Ahmed A. Moustafa and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Psychology categories.
A comprehensive Introduction to the world of brain and behavior computational models This book provides a broad collection of articles covering different aspects of computational modeling efforts in psychology and neuroscience. Specifically, it discusses models that span different brain regions (hippocampus, amygdala, basal ganglia, visual cortex), different species (humans, rats, fruit flies), and different modeling methods (neural network, Bayesian, reinforcement learning, data fitting, and Hodgkin-Huxley models, among others). Computational Models of Brain and Behavior is divided into four sections: (a) Models of brain disorders; (b) Neural models of behavioral processes; (c) Models of neural processes, brain regions and neurotransmitters, and (d) Neural modeling approaches. It provides in-depth coverage of models of psychiatric disorders, including depression, posttraumatic stress disorder (PTSD), schizophrenia, and dyslexia; models of neurological disorders, including Alzheimer’s disease, Parkinson’s disease, and epilepsy; early sensory and perceptual processes; models of olfaction; higher/systems level models and low-level models; Pavlovian and instrumental conditioning; linking information theory to neurobiology; and more. Covers computational approximations to intellectual disability in down syndrome Discusses computational models of pharmacological and immunological treatment in Alzheimer's disease Examines neural circuit models of serotonergic system (from microcircuits to cognition) Educates on information theory, memory, prediction, and timing in associative learning Computational Models of Brain and Behavior is written for advanced undergraduate, Master's and PhD-level students—as well as researchers involved in computational neuroscience modeling research.
Principles Of Computational Modelling In Neuroscience
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Author : David Sterratt
language : en
Publisher: Cambridge University Press
Release Date : 2023-10-05
Principles Of Computational Modelling In Neuroscience written by David Sterratt and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-05 with Science categories.
Learn to use computational modelling techniques to understand the nervous system at all levels, from ion channels to networks.
Computational Modelling In Behavioural Neuroscience
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Author : Dietmar Heinke
language : en
Publisher: Psychology Press
Release Date : 2009-04-03
Computational Modelling In Behavioural Neuroscience written by Dietmar Heinke and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-04-03 with Psychology categories.
Classically, behavioural neuroscience theorizes about experimental evidence in a qualitative way. However, more recently there has been an increasing development of mathematical and computational models of experimental results, and in general these models are more clearly defined and more detailed than their qualitative counter parts. These new computational models can be set up so that they are consistent with both single neuron and whole-system levels of operation, allowing physiological results to be meshed with behavioural data – thus closing the gap between neurophysiology and human behaviour. There is considerable diversity between models with respect to the methodology of designing a model, the degree to which neurophysiological processes are taken into account and the way data (behavioural, electrophysiological, etc) constrains a model. This book presents examples of this diversity and in doing so represents the state-of-art in the field through a unique collection of papers from the world's leading researchers in the area of computational modelling in behavioural neuroscience. Based on talks given at the third Behavioural Brain Sciences Symposium, held at the Behavioural Brain Sciences Centre, University of Birmingham, in May 2007, the book appeals to a broad audience, from postgraduate students beginning to work in the field to experienced experimenters interested in an overview.
Brain And Human Body Modeling
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Author : Sergey Makarov
language : en
Publisher: Springer Nature
Release Date : 2019-08-27
Brain And Human Body Modeling written by Sergey Makarov and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-08-27 with Technology & Engineering categories.
This open access book describes modern applications of computational human modeling with specific emphasis in the areas of neurology and neuroelectromagnetics, depression and cancer treatments, radio-frequency studies and wireless communications. Special consideration is also given to the use of human modeling to the computational assessment of relevant regulatory and safety requirements. Readers working on applications that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest developments in computational modelling and human phantom development to assess a given technology’s safety and efficacy in a timely manner. Describes construction and application of computational human models including anatomically detailed and subject specific models; Explains new practices in computational human modeling for neuroelectromagnetics, electromagnetic safety, and exposure evaluations; Includes a survey of modern applications for which computational human models are critical; Describes cellular-level interactions between the human body and electromagnetic fields.
Principles Of Computational Modelling In Neuroscience
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Author : David Sterratt
language : en
Publisher: Cambridge University Press
Release Date : 2011-06-30
Principles Of Computational Modelling In Neuroscience written by David Sterratt and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-30 with Medical categories.
The nervous system is made up of a large number of interacting elements. To understand how such a complex system functions requires the construction and analysis of computational models at many different levels. This book provides a step-by-step account of how to model the neuron and neural circuitry to understand the nervous system at all levels, from ion channels to networks. Starting with a simple model of the neuron as an electrical circuit, gradually more details are added to include the effects of neuronal morphology, synapses, ion channels and intracellular signalling. The principle of abstraction is explained through chapters on simplifying models, and how simplified models can be used in networks. This theme is continued in a final chapter on modelling the development of the nervous system. Requiring an elementary background in neuroscience and some high school mathematics, this textbook is an ideal basis for a course on computational neuroscience.
Neural And Computational Modeling Of Movement Control
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Author : Ning Lan
language : en
Publisher: Frontiers Media SA
Release Date : 2017-04-17
Neural And Computational Modeling Of Movement Control written by Ning Lan and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-04-17 with Electronic book categories.
In the study of sensorimotor systems, an important research goal has been to understand the way neural networks in the spinal cord and brain interact to control voluntary movement. Computational modeling has provided insight into the interaction between centrally generated commands, proprioceptive feedback signals and the biomechanical responses of the moving body. Research in this field is also driven by the need to improve and optimize rehabilitation after nervous system injury and to devise biomimetic methods of control in robotic devices. This research topic is focused on efforts dedicated to identify and model the neuromechanical control of movement. Neural networks in the brain and spinal cord are known to generate patterned activity that mediates coordinated activation of multiple muscles in both rhythmic and discrete movements, e.g. locomotion and reaching. Commands descending from the higher centres in the CNS modulate the activity of spinal networks, which control movement on the basis of sensory feedback of various types, including that from proprioceptive afferents. The computational models will continue to shed light on the central strategies and mechanisms of sensorimotor control and learning. This research topic demonstrated that computational modeling is playing a more and more prominent role in the studies of postural and movement control. With increasing ability to gather data from all levels of the neuromechanical sensorimotor systems, there is a compelling need for novel, creative modeling of new and existing data sets, because the more systematic means to extract knowledge and insights about neural computations of sensorimotor systems from these data is through computational modeling. While models should be based on experimental data and validated with experimental evidence, they should also be flexible to provide a conceptual framework for unifying diverse data sets, to generate new insights of neural mechanisms, to integrate new data sets into the general framework, to validate or refute hypotheses and to suggest new testable hypotheses for future experimental investigation. It is thus expected that neural and computational modeling of the sensorimotor system should create new opportunities for experimentalists and modelers to collaborate in a joint endeavor to advance our understanding of the neural mechanisms for postural and movement control. The editors would like to thank Professor Arthur Prochazka, who helped initially to set up this research topic, and all authors who contributed their articles to this research topic. Our appreciation also goes to the reviewers, who volunteered their time and effort to help achieve the goal of this research topic. We would also like to thank the staff members of editorial office of Frontiers in Computational Neuroscience for their expertise in the process of manuscript handling, publishing, and in bringing this ebook to the readers. The support from the Editor-in-Chief, Dr. Misha Tsodyks and Dr. Si Wu is crucial for this research topic to come to a successful conclusion. We are indebted to Dr. Si Li and Ms. Ting Xu, whose assistant is important for this ebook to become a reality. Finally, this work is supported in part by grants to Dr. Ning Lan from the Ministry of Science and Technology of China (2011CB013304), the Natural Science Foundation of China (No. 81271684, No. 61361160415, No. 81630050), and the Interdisciplinary Research Grant cross Engineering and Medicine by Shanghai Jiao Tong University (YG20148D09). Dr. Vincent Cheung is supported by startup funds from the Faculty of Medicine of The Chinese University of Hong Kong. Guest Associate Editors Ning Lan, Vincent Cheung, and Simon Gandevia
Validating Neuro Computational Models Of Neurological And Psychiatric Disorders
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Author : Basabdatta Sen Bhattacharya
language : en
Publisher: Springer
Release Date : 2015-10-30
Validating Neuro Computational Models Of Neurological And Psychiatric Disorders written by Basabdatta Sen Bhattacharya and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-30 with Medical categories.
This book is a collection of articles by leading researchers working at the cutting edge of neuro-computational modelling of neurological and psychiatric disorders. Each article contains model validation techniques used in the context of the specific problem being studied. Validation is essential for neuro-inspired computational models to become useful tools in the understanding and treatment of disease conditions. Currently, the immense diversity in neuro-computational modelling approaches for investigating brain diseases has created the need for a structured and coordinated approach to benchmark and standardise validation methods and techniques in this field of research. This book serves as a step towards a systematic approach to validation of neuro-computational models used for studying brain diseases and should be useful for all neuro-computational modellers.
Computational Neuroscience Models Of The Basal Ganglia
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Author : V. Srinivasa Chakravarthy
language : en
Publisher: Springer
Release Date : 2018-03-21
Computational Neuroscience Models Of The Basal Ganglia written by V. Srinivasa Chakravarthy and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-21 with Technology & Engineering categories.
The book is a compendium of the aforementioned subclass of models of Basal Ganglia, which presents some the key existent theories of Basal Ganglia function. The book presents computational models of basal ganglia-related disorders, including Parkinson’s disease, schizophrenia, and addiction. Importantly, it highlights the applications of understanding the role of the basal ganglia to treat neurological and psychiatric disorders. The purpose of the present book is to amend and expand on James Houk’s book (MIT press; ASIN: B010BF4U9K) by providing a comprehensive overview on computational models of the basal ganglia. This book caters to researchers and academics from the area of computational cognitive neuroscience.
Computational Modelling
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Author : Gary S. Dell
language : en
Publisher: Psychology Press
Release Date : 2019-02-04
Computational Modelling written by Gary S. Dell and has been published by Psychology Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-04 with categories.
The papers in the special issue describe computational models and principles that attempt to explain the performance of brain damaged subjects. The models elucidate the cognitive processes that underlie speaking, reading, spelling, and visuospatial planning by implementing hypothesized mechanisms and then identifying the consequences of specific "lesions" in these mechanisms for the model¿s behaviour which, in turn, is related to the subjects¿ behaviour. Although most of the presented models view cognitive mechanisms in connectionist or neural-network terms, they exhibit considerable variety in their underlying cognitive theories, their approach to modelling pathology, and particularly in how they use models to draw conclusions about theory.