Computational Nanotoxicology

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Computational Toxicology For Drug Safety And A Sustainable Environment
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Author : Tahmeena Khan, Saman Raza
language : en
Publisher: Bentham Science Publishers
Release Date : 2023-12-18
Computational Toxicology For Drug Safety And A Sustainable Environment written by Tahmeena Khan, Saman Raza and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-12-18 with Science categories.
Computational Toxicology for Drug Safety and a Sustainable Environment is a primer on computational techniques in environmental toxicology for scholars. The book presents 9 in-depth chapters authored by expert academicians and scientists aimed to give readers an understanding of how computational models, software and algorithms are being used to predict toxicological profiles of chemical compounds. The book also aims to help academics view toxicological assessment from the lens of sustainability by providing an overview of the recent developments in environmentally-friendly practices. The chapters review the strengths and weaknesses of the existing methodologies, and cover new developments in computational tools to explain how researchers aim to get accurate results. Each chapter features a simple introduction and list of references to benefit a broad range of academic readers. List of topics: 1. Applications of computational toxicology in pharmaceuticals, environmental and industrial practices 2. Verification, validation and sensitivity studies of computational models used in toxicology assessment 3. Computational toxicological approaches for drug profiling and development of online clinical repositories 4. How to neutralize chemicals that kill environment and humans: an application of computational toxicology 5. Adverse environmental impact of pharmaceutical waste and its computational assessment 6. Computational aspects of organochlorine compounds: DFT study and molecular docking calculations 7. In-silico studies of anisole and glyoxylic acid derivatives 8. Computational toxicology studies of chemical compounds released from firecrackers 9. Computational nanotoxicology and its applications Readership Graduate and postgraduate students, academics and researchers in pharmacology, computational biology, toxicology and environmental science programs.
Computational Nanotoxicology
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Author : Agnieszka Gajewicz
language : en
Publisher: CRC Press
Release Date : 2019-11-13
Computational Nanotoxicology written by Agnieszka Gajewicz and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-13 with Medical categories.
The development of computational methods that support human health and environmental risk assessment of engineered nanomaterials has attracted great interest because the application of these methods enables us to fill existing experimental data gaps. However, considering the high degree of complexity and multifunctionality of engineered nanoparticles, computational methods originally developed for regular (i.e., classic) chemicals cannot always be applied explicitly in nanotoxicology. Thus, the main idea of this book is to discuss the current state of the art and future needs in the development of computational modeling techniques for nanotoxicology. The book focuses on methodology. Among various in silico techniques, special attention is given to (i) computational chemistry (quantum mechanics, semi-empirical methods, density functional theory, molecular mechanics, molecular dynamics); (ii) nanochemoinformatic methods (quantitative structure–activity relationship modeling, grouping, read-across); and (iii) nanobioinformatic methods (genomics, transcriptomics, proteomics, metabolomics).
Nanotoxicology
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Author : Vineet Kumar
language : en
Publisher: CRC Press
Release Date : 2018-03-12
Nanotoxicology written by Vineet Kumar and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-03-12 with Medical categories.
As the application of nanotechnology in the myriad disciplines of science and engineering--from agriculture, pharmaceuticals, material science, and biotechnology to sensors, electronics, and mechanical and electrical engineering--brings benefits it also can produce serious threats to human health and the environment that must be evaluated. The unique properties of nanomaterials make them different from their bulk counterparts. In addition to such unique properties, the nanometric size of nanomaterials can invite some detrimental effects on the health and well-being of living organisms and the environment. Thus, it is important to distinguish nanomaterials with such ill effects from nanomaterials with no or minimum toxicity. Nanotoxicology: Toxicity Evaluation, Risk Assessment and Management covers issues such as the basic principles of nanotoxicity, methods used for nanotoxicity evaluation, risk assessment and its management for nanomaterial toxicity with a focus on current trends, limitations, challenges, and future directions of nanotoxicity evaluation. Various experts from different countries discuss these issues in detail in this book. This will be helpful to researchers, educators, and students who are interested in research opportunities for avoiding the environmental and health hazards of nanomaterials. This book will also be useful for industrial practitioners, policy makers, and other professionals in the fields of toxicology, medicine, pharmacology, food, drugs, and other regulatory sciences.
Nanotoxicology
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Author : Nancy A. Monteiro-Riviere
language : en
Publisher: CRC Press
Release Date : 2014-03-03
Nanotoxicology written by Nancy A. Monteiro-Riviere and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-03-03 with Medical categories.
Since the first publication of this book in 2007, the field of nanoscience and nanomedicine continues to grow substantially. This second edition, Nanotoxicology: Progress toward Nanomedicine, enlists internationally recognized experts to document the continuing development and rationale for the safe design of engineered nanomaterials (ENM). This in
Handbook Of Nanotoxicology Nanomedicine And Stem Cell Use In Toxicology
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Author : Saura C. Sahu
language : en
Publisher: John Wiley & Sons
Release Date : 2014-04-22
Handbook Of Nanotoxicology Nanomedicine And Stem Cell Use In Toxicology written by Saura C. Sahu and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-04-22 with Science categories.
The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.
Nanotoxicology In Nanobiomedicine
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Author : PK Gupta
language : en
Publisher: Springer Nature
Release Date : 2023-03-20
Nanotoxicology In Nanobiomedicine written by PK Gupta and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-20 with Medical categories.
This book provides that knowledge needed to introduce individuals to the most important research and content on nanotoxicology in nanobiomedicine. Nanotechnology is helping to considerably improve, even revolutionize many technology and industry sectors: information technology, homeland security, medicine, transportation, energy, food safety, and environmental science, among many others. There is an urgent need for a general reference textbook that presents the most recent information on the toxicity and its effects in all these sectors, biomedicine in particular. It includes historical information, nanotoxicology by subject area and or disease, sources of nanomaterials, drug delivery systems and more. Scientists, researchers, and students in all fields that use nanotechnology will find this book essential reading.
Nanotoxicology
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Author : Alok Dhawan
language : en
Publisher: Royal Society of Chemistry
Release Date : 2017-11-13
Nanotoxicology written by Alok Dhawan and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-11-13 with Medical categories.
This book fills the significant nanotoxicology and nanosafety knowledge gaps and covers a broad range of topics. It targets postgraduates, academics, and practicing industrialists.
Grid Computing For Bioinformatics And Computational Biology
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Author : El-Ghazali Talbi
language : en
Publisher: John Wiley & Sons
Release Date : 2007-12-04
Grid Computing For Bioinformatics And Computational Biology written by El-Ghazali Talbi and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-12-04 with Computers categories.
The only single, up-to-date source for Grid issues in bioinformatics and biology Bioinformatics is fast emerging as an important discipline for academic research and industrial applications, creating a need for the use of Grid computing techniques for large-scale distributed applications. This book successfully presents Grid algorithms and their real-world applications, provides details on modern and ongoing research, and explores software frameworks that integrate bioinformatics and computational biology. Additional coverage includes: * Bio-ontology and data mining * Data visualization * DNA assembly, clustering, and mapping * Molecular evolution and phylogeny * Gene expression and micro-arrays * Molecular modeling and simulation * Sequence search and alignment * Protein structure prediction * Grid infrastructure, middleware, and tools for bio data Grid Computing for Bioinformatics and Computational Biology is an indispensable resource for professionals in several research and development communities including bioinformatics, computational biology, Grid computing, data mining, and more. It also serves as an ideal textbook for undergraduate- and graduate-level courses in bioinformatics and Grid computing.
Environmental Nanotoxicology
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Author : Patrick Omoregie Isibor
language : en
Publisher: Springer Nature
Release Date : 2024-03-19
Environmental Nanotoxicology written by Patrick Omoregie Isibor and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-19 with Technology & Engineering categories.
Environmental Nanotoxicology: Combatting the Minute Contaminants is a comprehensive guide to the rapidly evolving field of nanotoxicology and its implications for environmental health and safety. This book results from the collaborative efforts of leading experts and researchers from diverse disciplines, aiming to thoroughly understand the interactions between nanomaterials and the environment and their potential impacts on the delicate balance of our ecosystems. Nanotechnology has witnessed remarkable innovations leading to the development of nanomaterials with novel properties and applications across various industries. Alongside these innovations, concerns have arisen about the potential risks that nanomaterials may pose to the environment and living organisms. This book addresses these concerns by comprehensively exploring the field's key concepts, principles, and methodologies. It includes case studies and offers insights into developing appropriate regulatoryframeworks and guidelines for the responsible use and disposal of nanomaterials. The book is a valuable resource for researchers and professionals working in nanotoxicology on the complex challenges posed by the intersection of nanomaterials and the environment. It is also an essential reference for students studying environmental science, toxicology, and nanotechnology.
Nanotoxicology
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Author : Hemant Kumar Daima
language : en
Publisher: CRC Press
Release Date : 2021-07-14
Nanotoxicology written by Hemant Kumar Daima and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-14 with Medical categories.
The field of nanomedicine has risen quickly due to the increasing number of designer-made nanomaterials. These nanomaterials have the potential to manage diseases and change the way medicine is currently studied. However, the increased practice of using nanomaterials has shed light on how many concepts of nanomedicine and nanotoxicity have been overlooked. Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications addresses the existing gaps between nanomedicine and nanotoxicity. This book also brings together up-to-date knowledge on advances toward safe-by-design nanomaterials and existing toxicity challenges. This book delivers a comprehensive coverage in the field with fundamental understanding, serving as a platform to convey essential concepts of nanotoxicology and how these concepts can be employed to develop advanced nanomaterials for a range of biomedical applications. This book is an effort to answer some of the thoughtful nanotoxicological complications and their auspicious probable solutions with new approaches and careful toxicity assessment. Key Features: Reveals novel nanoscale approaches, toxicity assessment, and biomedical applications Includes importance of nanotoxicity concepts in developing smart nanomaterials Highlights unique contributions and "A to Z" aspects on the state-of-the-art from global leaders Offers a complete package to learn fundamentals with recommendations on nanomaterials toxicity and safe-by-design nanomedicines Nanotoxicology: Toxicity Evaluation of Nanomedicine Applications illuminates the high potential of many innovative nanomaterials, ultimately demonstrating them to be promising substitutes for available therapies that can be effectively used in fighting a myriad of biomedical complications. Further, this book reports legal, ethical, safety, and regulatory issues associated with nanomaterials, which have often been neglected, if not overlooked in literature and limiting clinical translation at nanoscale level. It will equip readers with cutting-edge knowledge of promising developments in nanomedicine and nanotoxicology, along with potential future prospects.