Computer Simulation Study Of Collective Phenomena In Dense Suspensions Of Red Blood Cells Under Shear

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Computer Simulation Study Of Collective Phenomena In Dense Suspensions Of Red Blood Cells Under Shear

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Author : Timm Krüger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-02

Computer Simulation Study Of Collective Phenomena In Dense Suspensions Of Red Blood Cells Under Shear written by Timm Krüger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-02 with Science categories.

The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of the work, the numerical model and strategies for stress evaluation are discussed. In the second part, the behavior of the suspensions in simple shear flow is studied for different volume fractions, particle deformabilities, and shear rates. Shear thinning behavior is recovered. The existence of a shear-induced transition from a tumbling to a tank-treading motion is demonstrated. The transition can be parameterized by a single quantity, namely the effective capillary number. It is the ratio of the suspension stress and the characteristic particle membrane stress. At the transition point, a strong increase in the orientational order of the red blood cells and a significant decrease of the particle diffusivity are observed. However, the average cell deformation shows no signature of the transition.

Computer Simulation Study Of Collective Phenomena In Dense Suspensions Of Red Blood Cells Under Shear

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Author : Heinrich Krüger
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-07-18

Computer Simulation Study Of Collective Phenomena In Dense Suspensions Of Red Blood Cells Under Shear written by Heinrich Krüger and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-07-18 with Science categories.

The rheology of dense red blood cell suspensions is investigated via computer simulations based on the lattice Boltzmann, the immersed boundary, and the finite element methods. The red blood cells are treated as extended and deformable particles immersed in the ambient fluid. In the first part of the work, the numerical model and strategies for stress evaluation are discussed. In the second part, the behavior of the suspensions in simple shear flow is studied for different volume fractions, particle deformabilities, and shear rates. Shear thinning behavior is recovered. The existence of a shear-induced transition from a tumbling to a tank-treading motion is demonstrated. The transition can be parameterized by a single quantity, namely the effective capillary number. It is the ratio of the suspension stress and the characteristic particle membrane stress. At the transition point, a strong increase in the orientational order of the red blood cells and a significant decrease of the particle diffusivity are observed. However, the average cell deformation shows no signature of the transition.

Computational Blood Cell Mechanics

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Author : Ivan Cimrak
language : en
Publisher: CRC Press
Release Date : 2018-09-06

Computational Blood Cell Mechanics written by Ivan Cimrak and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-06 with Mathematics categories.

Simulating blood cells for biomedical applications is a challenging goal. Whether you want to investigate blood flow behavior on the cell scale, or use a blood cell model for fast computational prototyping in microfluidics, Computational Blood Cell Mechanics will help you get started, and show you the path forward. The text presents a step-by-step approach to cell model building that can be adopted when developing and validating models for biomedical applications, such as filtering and sorting cells, or examining flow and deformations of individual cells under various conditions. It starts with basic building-blocks that, together, model the red blood cell membrane according to its physical properties, before moving on to discuss several issues that may pose problems along the way, and finally leads to suggestions on how to set up computational experiments. More details available at www.compbloodcell.eu

High Performance Computing In Science And Engineering 17

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Author : Wolfgang E. Nagel
language : en
Publisher: Springer
Release Date : 2018-02-16

High Performance Computing In Science And Engineering 17 written by Wolfgang E. Nagel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-02-16 with Computers categories.

This book presents the state-of-the-art in supercomputer simulation. It includes the latest findings from leading researchers using systems from the High Performance Computing Center Stuttgart (HLRS) in 2017. The reports cover all fields of computational science and engineering ranging from CFD to computational physics and from chemistry to computer science with a special emphasis on industrially relevant applications. Presenting findings of one of Europe’s leading systems, this volume covers a wide variety of applications that deliver a high level of sustained performance.The book covers the main methods in high-performance computing. Its outstanding results in achieving the best performance for production codes are of particular interest for both scientists and engineers. The book comes with a wealth of color illustrations and tables of results.

Multiscale Modeling Of Vascular Dynamics Of Micro And Nano Particles

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Author : Huilin Ye
language : en
Publisher: Morgan & Claypool Publishers
Release Date : 2020-01-02

Multiscale Modeling Of Vascular Dynamics Of Micro And Nano Particles written by Huilin Ye and has been published by Morgan & Claypool Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-02 with Science categories.

Recent advances witness the potential to employ nanomedicine and game-changing methods to deliver drug molecules directly to diseased sites. To optimize and then enhance the efficacy and specificity, the control and guidance of drug carriers in vasculature has become crucial. Current bottlenecks in the optimal design of drug carrying particles are the lack of knowledge about the transport of particles, adhesion on endothelium wall and subsequent internalization into diseased cells. To study the transport and adhesion of particle in vasculature, the authors have made great efforts to numerically investigate the dynamic and adhesive motions of particles in the blood flow. This book discusses the recent achievements from the establishment of fundamental physical problem to development of multiscale model, and finally large scale simulations for understanding transport of particle-based drug carriers in blood flow.

Frontiers In Synaptic Neuroscience Editor S Pick 2021

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Author : P. Jesper Sjöström
language : en
Publisher: Frontiers Media SA
Release Date : 2021-07-21

Frontiers In Synaptic Neuroscience Editor S Pick 2021 written by P. Jesper Sjöström and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-21 with Science categories.

The Lattice Boltzmann Method

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Author : Timm Krüger
language : en
Publisher: Springer
Release Date : 2016-11-07

The Lattice Boltzmann Method written by Timm Krüger and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-11-07 with Science categories.

This book is an introduction to the theory, practice, and implementation of the Lattice Boltzmann (LB) method, a powerful computational fluid dynamics method that is steadily gaining attention due to its simplicity, scalability, extensibility, and simple handling of complex geometries. The book contains chapters on the method's background, fundamental theory, advanced extensions, and implementation. To aid beginners, the most essential paragraphs in each chapter are highlighted, and the introductory chapters on various LB topics are front-loaded with special "in a nutshell" sections that condense the chapter's most important practical results. Together, these sections can be used to quickly get up and running with the method. Exercises are integrated throughout the text, and frequently asked questions about the method are dealt with in a special section at the beginning. In the book itself and through its web page, readers can find example codes showing how the LB method can be implemented efficiently on a variety of hardware platforms, including multi-core processors, clusters, and graphics processing units. Students and scientists learning and using the LB method will appreciate the wealth of clearly presented and structured information in this volume.

Physics Briefs

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Author :
language : en
Publisher:
Release Date : 1993

Physics Briefs written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Physics categories.

Flowing Matter

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Author : Federico Toschi
language : en
Publisher: Springer Nature
Release Date : 2019-09-25

Flowing Matter written by Federico Toschi and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-09-25 with Science categories.

This open access book, published in the Soft and Biological Matter series, presents an introduction to selected research topics in the broad field of flowing matter, including the dynamics of fluids with a complex internal structure -from nematic fluids to soft glasses- as well as active matter and turbulent phenomena. Flowing matter is a subject at the crossroads between physics, mathematics, chemistry, engineering, biology and earth sciences, and relies on a multidisciplinary approach to describe the emergence of the macroscopic behaviours in a system from the coordinated dynamics of its microscopic constituents. Depending on the microscopic interactions, an assembly of molecules or of mesoscopic particles can flow like a simple Newtonian fluid, deform elastically like a solid or behave in a complex manner. When the internal constituents are active, as for biological entities, one generally observes complex large-scale collective motions. Phenomenology is further complicated by the invariable tendency of fluids to display chaos at the large scales or when stirred strongly enough. This volume presents several research topics that address these phenomena encompassing the traditional micro-, meso-, and macro-scales descriptions, and contributes to our understanding of the fundamentals of flowing matter. This book is the legacy of the COST Action MP1305 “Flowing Matter”.

Theory And Applications Of Colloidal Suspension Rheology

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Author : Norman J. Wagner
language : en
Publisher: Cambridge University Press
Release Date : 2021-04-15

Theory And Applications Of Colloidal Suspension Rheology written by Norman J. Wagner and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-15 with Science categories.

Essential text on the practical application and theory of colloidal suspension rheology, written by an international coalition of experts.