Computing For Comparative Microbial Genomics
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Computing For Comparative Microbial Genomics
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Author : David Wayne Ussery
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-02-26
Computing For Comparative Microbial Genomics written by David Wayne Ussery and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-02-26 with Science categories.
Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.
Computing For Comparative Microbial Genomics
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Author : David Wayne Ussery
language : en
Publisher: Springer Science & Business Media
Release Date : 2008-12-16
Computing For Comparative Microbial Genomics written by David Wayne Ussery and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-12-16 with Science categories.
Overview and Goals This book describes how to visualize and compare bacterial genomes. Sequencing technologies are becoming so inexpensive that soon going for a cup of coffee will be more expensive than sequencing a bacterial genome. Thus, there is a very real and pressing need for high-throughput computational methods to compare hundreds and thousands of bacterial genomes. It is a long road from molecular biology to systems biology, and in a sense this text can be thought of as a path bridging these ? elds. The goal of this book is to p- vide a coherent set of tools and a methodological framework for starting with raw DNA sequences and producing fully annotated genome sequences, and then using these to build up and test models about groups of interacting organisms within an environment or ecological niche. Organization and Features The text is divided into four main parts: Introduction, Comparative Genomics, Transcriptomics and Proteomics, and ? nally Microbial Communities. The ? rst ? ve chapters are introductions of various sorts. Each of these chapters represents an introduction to a speci? c scienti? c ? eld, to bring all readers up to the same basic level before proceeding on to the methods of comparing genomes. First, a brief overview of molecular biology and of the concept of sequences as biological inf- mation are given.
Microbial Pathogenomics
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Author : H. de Reuse
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2009-08-27
Microbial Pathogenomics written by H. de Reuse and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-08-27 with Science categories.
Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies - computational tools and functional approaches to genome analysis - are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'. 'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.
Grid Computing In Life Science
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Author : Akihiko Konagaya
language : en
Publisher: Springer Science & Business Media
Release Date : 2005-03-07
Grid Computing In Life Science written by Akihiko Konagaya and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-03-07 with Computers categories.
This book constitutes the thoroughly refereed postproceedings of the First International Life Science Grid Workshop, LSGRID 2004, held in Kanazawa, Japan in May/ June 2004. The 10 revised full papers and 5 invited papers presented were carefully selected and went through two rounds of reviewing and revision. Among the topics addressed are grid environment for bioinformatics, grid architectures, database federation, proteome annotation, grid workflow software, functional genome annotation, protein classification, tree inference, parallel computing, high performance computing, grid infrastructures, functional genomics, and evolutionary algorithms.
Beneficial Microorganisms In Agriculture Food And The Environment
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Author : Ingvar Sundh
language : en
Publisher: CABI
Release Date : 2012
Beneficial Microorganisms In Agriculture Food And The Environment written by Ingvar Sundh and has been published by CABI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Agricultural microbiology categories.
Microorganisms are widely used in various beneficial applications, including food, pest control, bioremediation, biodegradation, biofuel processes, and plant symbiosis and growth stimulation. This book provides an overview of the available methodology for safety assessments of microorganisms, including determination of their infectivity and whether they produce toxic or sensitizing substances. Also covered are the regulatory systems in risk assessment and management of microbial products, quarantine legislations, international treaties, the importance of public risk perception and risk reducti
Microbial Diversity In Ecosystem Sustainability And Biotechnological Applications
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Author : Tulasi Satyanarayana
language : en
Publisher: Springer
Release Date : 2019-07-17
Microbial Diversity In Ecosystem Sustainability And Biotechnological Applications written by Tulasi Satyanarayana and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-17 with Science categories.
This book discusses microbial diversity in various habitats and environments, its role in ecosystem maintenance, and its potential applications (e.g. biofertilizers, biocatalysts, antibiotics, other bioactive compounds, exopolysaccharides etc.). The respective chapters, all contributed by renowned experts, offer cutting-edge information in the fields of microbial ecology and biogeography. The book explains the reasons behind the occurrence of various biogeographies and highlights recent tools (e.g. metagenomics) that can aid in biogeography studies by providing information on nucleic acid sequence data, thereby directly identifying microorganisms in various habitats and environments. In turn, the book describes how human intervention results in depletion of biodiversity, and how numerous hotspots are now losing their endemic biodiversity, resulting in the loss of many ecologically important microorganisms. In closing, the book underscores the importance of microbial diversity for sustainable ecosystems.
Management Of Microbial Resources In The Environment
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Author : Abdul Malik
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-02-26
Management Of Microbial Resources In The Environment written by Abdul Malik and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-02-26 with Science categories.
This volume details the exploration, collection, characterization, evaluation and conservation of microbes for sustainable utilization in the development of the global as well as national economies, e.g. in agriculture, ecosystems, environments, industry and medicine. Many research institutes and universities all over the world carry out microbiological and biotechnological research, which generates substantial genomic resources such as cDNA libraries, gene constructs, promoter regions, transgenes and more valuable assets for gene discovery and transgenic product development. This work provides up-to-date information on the management of microbial resources in the environment. It also covers the ecology of microorganisms in natural and engineered environments. In trying to understand microbial interactions it further focuses on genomic, metagenomic and molecular advances, as well as on microbial diversity and phylogeny; ecological studies of human, animal and plant microbiology and disease; microbial processes and interactions in the environment; and key technological advances. Though not intended to serve as an encyclopedic review of the subject, the various chapters investigate both theoretical and practical aspects and provide essential basic information for future research to support continued development.
Bacteria
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Author : Trudy M. Wassenaar
language : en
Publisher: John Wiley & Sons
Release Date : 2012-11-12
Bacteria written by Trudy M. Wassenaar and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-12 with Medical categories.
"This book introduces bacteria and basic microbiological concepts to readers without previous background in the subject. Each chapter concentrates on a particular topic and can be read in isolation or as part of the whole, and wherever possible points are illustrated through real-world examples and short stories. Although bacterial scientific names are used and translated when possible, in general scientific jargon is avoided in order to make the material as accessible as possible for the lay reader"--
Infectious Disease Informatics
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Author : Vitali Sintchenko
language : en
Publisher: Springer Science & Business Media
Release Date : 2009-12-08
Infectious Disease Informatics written by Vitali Sintchenko and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-08 with Medical categories.
There are several reasons to be interested in infectious disease informatics. First, it is of practical significance to understand how the technology revolution has been reshaping infectious disease research and management, as rapid advances in geno- associated technologies have changed the very nature of the questions we can ask. Second, the emerging evidence has confirmed that the application of information technologies in healthcare enhances our ability to deal with infectious diseases. Finally, the implementation of electronic health records has created new and exciting opportunities for secure, reliable and ethically sound clinical decision support and biosurveillance guided by the genomics of pathogens with epidemic potential. This volume addresses the growing need for the critical overview of recent developments in microbial genomics and biomedical informatics relevant to the control of infectious diseases. This field is rapidly expanding, and attracts a wide audience of clinicians, public health professionals, biomedical researchers and computer scientists who are fascinated by the complex puzzle of infectious disease. This book takes a multidisciplinary approach with a calculated move away from the traditional health informatics topics of computerized protocols for antibiotic p- scribing and pathology testing. Instead authors invite you to explore the emerging frontiers of bioinformatics-guided pathogen profiling, the system microbiolo- enabled intelligent design of new drugs and vaccines, and new ways of real-time biosurveillance and hospital infection control. Throughout the book, references are made to different products supplied by public sources and commercial vendors, but this is not an endorsement of these products or vendors.
Energy And Water Development Appropriations For Fiscal Year
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Author : United States. Congress. Senate. Committee on Appropriations. Subcommittee on Energy and Water Development
language : en
Publisher:
Release Date : 2005
Energy And Water Development Appropriations For Fiscal Year written by United States. Congress. Senate. Committee on Appropriations. Subcommittee on Energy and Water Development and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005 with Energy development categories.