Conformation Of Biological Molecules

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Conformation Of Biological Molecules

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Author : G. Govil
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Conformation Of Biological Molecules written by G. Govil and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

The determination of the three-dimensional structure of a biological molecule is the starting point in the understanding of molecular mechanisms involved in its complex biochemical reactions. The molecular architecture of multimolecular systems such as membranes and chromosomes provides the key to the fascinating field of molecular biology. Stereochemical details of biological macromolecules and their interactions with pharmacological agents form the basis for drug design. Naturally, the study of the structure and function of biological molecules has aroused tremendous interest and investigations in this area are being carried out in a large number of laboratories. The techniques used for this purpose include both experimental methods (X-ray and neutron diffraction measurements, study of NMR, ESR, vibrational and electronic spectra, ORD, CD and dipole moment measurements, biochemical modifications etc. ) and the oretical methods (quantum mechanical and classical potential energy calculations, Monte Carlo simulations and molecular graphics). F or several years now, X-ray diffraction [1] has served as our only source of infor mation on the three-dimensional arrangements of atoms in biopolymers. Fiber-diffrac tion of DNA led to the proposal of the DNA double helix. Fibers of long~hain polymers show ordering in the direction of the fibre-axis but not in the transverse plane. Accurate estimates of the dimensions of helical structures can be made using techniques on the basis of which models of biopolymers can be constructed.

Circular Dichroism And The Conformational Analysis Of Biomolecules

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Author : G.D. Fasman
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-11

Circular Dichroism And The Conformational Analysis Of Biomolecules written by G.D. Fasman and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-11 with Science categories.

''Excellent and very timely....It will undoubtedly become a standard reference for the application of circular dichroism (CD) to biomolecules.'' --- Quarterly Review of Biology, March 1997 ''[T]estament to the book's utility is the fact that during the course of my review I had to 'rescue' it from the desks of graduate students on an almost daily basis. In summary, this is a great book.'' --- American Scientist ''Well documented chapters provide a very good insight into the problems surrounding the conformation of biomacromolecules...An indispensible source of information.'' --- Nahrung, 42(2), 1998 Renowned experts present the first state-of-the-art description of circular dichroism spectroscopy (CD). Chapters present in-depth discussions of the history of the field, the theory of CD for application to globular proteins, membrane proteins, peptides, nucleic acids and their interactions, carbohydrates, and instrumentation. Discussions also feature new techniques using synchrotron radiation, vibrational Raman optical activity, and vibrational CD. More than 250 illustrations supplement the text.

Dynamic Aspects Of Conformation Changes In Biological Macromolecules

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Author : C. Sadron
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Dynamic Aspects Of Conformation Changes In Biological Macromolecules written by C. Sadron and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.

On the day after the 1959 Cambridge Congress, during which the International Union of Pure and Applied Biophysics was founded, a biophysics section was formed within the Society of Physical Chemistry (Societe de Chimie Physique). Since then, three of the Society's annual meetings (the 11th, 17th, and 23rd) were devoted exclusively to the physico-chemical study of biological systems. The first of these was held in June 1961 at a hotel in Col de Voza, at the foot of an alpine glacier above Chamonix. The second, in May 1967, took place in the more learned setting of the venerable rooms of the National Museum of Natural History in Paris. The third - the one dealt with in the present volume - was recently held at Orleans-La Source in the newly built lecture theatres of the young University, which is near the great Institutes of the National Centre for Scientific Research (CNRS), on the Sologne plateau. These three stages are milestones of an evolution which characterises (at least schematically) the explosive evolution of biological physico-chemistry. The first colloquium, with the title 'Deoxyribonucleic Acid: Structure, Synthesis and Functions', actually marks the first contact of the physical chemist with one of the then most prestigious biological macromolecules, the structure of which had just been discovered, and in this way celebrated one of the first and most striking successes of molecular biology.

Conformation Of Biological Molecules And Polymers

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Author : Ernst David Bergmann
language : en
Publisher: Academic Press
Release Date : 1973

Conformation Of Biological Molecules And Polymers written by Ernst David Bergmann and has been published by Academic Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1973 with Science categories.

Accuracy of potential functions in the analysis of biopolymer coformation; The dipeptide model-its significance and limitations; Conformational properties of peptides deduced from energy calculations; Interactions in polypertides and proteins; Experimental study of the conformation of dipeptides; Dipole moments and conformations of dipeptides in solution.

Molecular Biology Of The Cell

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Author :
language : en
Publisher:
Release Date : 2004

Molecular Biology Of The Cell written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Cells categories.

Nmr

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Author : Girjesh Govil
language : en
Publisher:
Release Date : 1981

Nmr written by Girjesh Govil and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1981 with Conformational analysis categories.

Biophysical Chemistry

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Author : Charles R. Cantor
language : en
Publisher: Macmillan
Release Date : 1980

Biophysical Chemistry written by Charles R. Cantor and has been published by Macmillan this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Biochemistry categories.

Macromolecules

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Author : F Bovey
language : en
Publisher: Elsevier
Release Date : 2012-12-02

Macromolecules written by F Bovey and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-02 with Science categories.

Macromolecules is an introductory book about macromolecules, specifically about the fundamental aspects of macromolecules, such as their nature, the ways they are formed, and their behavior. This book also focuses on the basics of macromolecules, which includes history, composition, and properties. The topics covered in this book include polymerization kinetics, chemical reactions, and degradation of macromolecules. This book also discusses biological molecules, including naturally occurring materials, synthetic macromolecules, and model compounds. Students majoring in chemistry or other related fields, such as materials engineering, will find this book very useful.

Conformation In Biology And Drug Design

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Author : Sidney Udenfriend
language : en
Publisher: Elsevier
Release Date : 2014-05-10

Conformation In Biology And Drug Design written by Sidney Udenfriend and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-10 with Science categories.

The Peptides: Analysis, Synthesis, Biology, Volume 7: Conformation in Biology and Drug Design focuses on the analysis of peptides, emphasizing the use of physical methods in peptide conformational analysis and the relationship of conformational properties of peptides to biological properties. This book consists of nine chapters. Chapter 1 provides a brief overview of the perspective on the application of physical methods to peptide conformational analysis. The use of circular dichroism (CD) spectroscopy to examine the conformational properties of peptides in solution is elaborated in Chapter 2, while the use of fluorescence spectroscopy to examine the special relationships of aromatic side-chain groups to one another is discussed in Chapter 3. In Chapter 4, the use of various theoretical methods to calculate the conformations of peptides is described. The methods used to stimulate peptide conformations and dynamics are outlined in Chapter 5. The last four chapters examine various aspects of the use of nuclear magnetic resonance (NMR) in peptide conformational analysis. This volume is suitable for biologists, specialists, and researchers interested in peptides and proteins.

Opportunities In Biology

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Author : National Research Council
language : en
Publisher: National Academies
Release Date : 1989-01-01

Opportunities In Biology written by National Research Council and has been published by National Academies this book supported file pdf, txt, epub, kindle and other format this book has been release on 1989-01-01 with Science categories.

Biology has entered an era in which interdisciplinary cooperation is at an all-time high, practical applications follow basic discoveries more quickly than ever before, and new technologiesâ€"recombinant DNA, scanning tunneling microscopes, and moreâ€"are revolutionizing the way science is conducted. The potential for scientific breakthroughs with significant implications for society has never been greater. Opportunities in Biology reports on the state of the new biology, taking a detailed look at the disciplines of biology; examining the advances made in medicine, agriculture, and other fields; and pointing out promising research opportunities. Authored by an expert panel representing a variety of viewpoints, this volume also offers recommendations on how to meet the infrastructure needsâ€"for funding, effective information systems, and other supportâ€"of future biology research. Exploring what has been accomplished and what is on the horizon, Opportunities in Biology is an indispensable resource for students, teachers, and researchers in all subdisciplines of biology as well as for research administrators and those in funding agencies.