Conformational Concept For Synthetic Chemist S Use Principles And In Lab Exploitation
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Conformational Concept For Synthetic Chemist S Use Principles And In Lab Exploitation
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Author : Anatoly M Belostotskii
language : en
Publisher: World Scientific
Release Date : 2015-09-17
Conformational Concept For Synthetic Chemist S Use Principles And In Lab Exploitation written by Anatoly M Belostotskii and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-09-17 with Science categories.
This innovative book presents an original account of the principles of conformational theory. It has a strong focus on computational methodologies for conformational space exploration. By revisiting basic conformational conventions, considering experimental results which are often misinterpreted by organic chemists, and qualitatively analyzing the potential energy surface, the book helps non-experts to understand molecular flexibility at the level required in contemporary research.The book shows synthetic organic chemists how to perform successful conformational studies using widespread calculation packages ('click computational chemistry') instead of being misguided by textbook-based conformational analysis. The monograph actually offers to synthetic chemists a new research tool that can significantly upgrade their ability to predict, or at least explain, regioselectivity and stereoselectivity in their own reactions.
Comprehensive Supramolecular Chemistry Ii
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Author : George W. Gokel
language : en
Publisher: Elsevier
Release Date : 2017-06-22
Comprehensive Supramolecular Chemistry Ii written by George W. Gokel and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-06-22 with Science categories.
Comprehensive Supramolecular Chemistry II, Second Edition, Nine Volume Set is a ‘one-stop shop’ that covers supramolecular chemistry, a field that originated from the work of researchers in organic, inorganic and physical chemistry, with some biological influence. The original edition was structured to reflect, in part, the origin of the field. However, in the past two decades, the field has changed a great deal as reflected in this new work that covers the general principles of supramolecular chemistry and molecular recognition, experimental and computational methods in supramolecular chemistry, supramolecular receptors, dynamic supramolecular chemistry, supramolecular engineering, crystallographic (engineered) assemblies, sensors, imaging agents, devices and the latest in nanotechnology. Each section begins with an introduction by an expert in the field, who offers an initial perspective on the development of the field. Each article begins with outlining basic concepts before moving on to more advanced material. Contains content that begins with the basics before moving on to more complex concepts, making it suitable for advanced undergraduates as well as academic researchers Focuses on application of the theory in practice, with particular focus on areas that have gained increasing importance in the 21st century, including nanomedicine, nanotechnology and medicinal chemistry Fully rewritten to make a completely up-to-date reference work that covers all the major advances that have taken place since the First Edition published in 1996
Bionanodesign
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Author : Maxim Ryadnov
language : en
Publisher: Royal Society of Chemistry
Release Date : 2009-09-30
Bionanodesign written by Maxim Ryadnov and has been published by Royal Society of Chemistry this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-09-30 with Technology & Engineering categories.
The progress of today's science and technology encounters an increasing demand for finer and more efficiently performing materials with properties superior over those of current and hence ageing devices. Whether this is concerned with electronics or drug delivery, cancer diagnostics or alternative energy sources, the search for means of miniaturizing the existing materials or devising fundamentally new components with higher capacities appears to be relentless. A saving solution to this is widely proposed as the design and fabrication of nanostructures, molecular architectures with dimensions featured below 100 nm. Replicating Nature's designs faithfully reproduced over millions of years provides perhaps the most straightforward route to success. Nature offers examples of nanodefined self-assemblies in virtually all levels of biological organization. However explicit guidance to the fabrication of functional or specialist nanostructures is of paramount importance. Nanotechnology is often referred to as building nanoscale structures from bottom up. However, while it is visually clear what is at "up" little is given and understood what is at the "bottom". This new book gives the notion of and provides rules for building nanostructures from basics - the very bottom. The main objective of this publication is to bring together contemporary approaches for designing nanostructures that employ naturally derived self-assembling motifs as synthetic platforms. The book has been written to satisfy the demands that motivate the search for and principles that prove to help the design of novel nanostructures. The overall goal is to compile the existing understanding of rules that govern biomolecular self-assembly into a practical guide to molecular nanotechnology. It is written in the shape of a review referenced as fully as permissible within the context of biomolecular design, which forms a general trend throughout. The volume is composed of three core chapters focusing on three prominent topics of applied nanotechnology where the role of nanodesign is predominant. The three key areas from which popular highlights can be drawn are: -employing the genetic repository, DNA, for creating various geometric nanoscale objects and patterns -the empirical pursuit of an artificial virus, a magic bullet in gene therapy -designing artificial extracellular matrices for regenerative medicine Specific applications that arise from designed nanoscale assemblies as well as fabrication and characterization techniques are of secondary importance and whenever they appear serve as progress and innovation highlights. The book takes an unconventional approach in delivering material of this kind. It does not lead straight to applications or methods as most nanotechnology works tend to do, but instead it focuses on the initial and primary aspect of "nano" rather than on "technology". Nanodesign is unique in its own field - illustrations are essential and the cohort of brilliant bioinspired designs reported to date form a major part of the publication. In addition, key bibliographic references are covered as fully as possible. A special appendix giving a short list of leading world laboratories engaged in bioinspired nanodesign is also included.
Chemogenomics And Chemical Genetics
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Author : ERIC MARECHAL
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-06-21
Chemogenomics And Chemical Genetics written by ERIC MARECHAL and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-06-21 with Science categories.
Biological and chemical sciences have undergone an unprecedented transformation, reflected by the huge use of parallel and automated technologies in key fields such as genome sequencing, DNA chips, nanoscale functional biology or combinatorial chemistry. It is now possible to generate and store from tens of thousands to millions of new small molecules, based on enhanced chemical synthesis strategies. Automated screening of small molecules is one of the technologies that has revolutionized biology, first developed for the pharmaceutical industry and recently introduced in academic laboratories. High-throughput and high-content screening allow the identification of bioactive compounds in collections of molecules (chemical libraries), being effective on biological targets defined at various organisational scales, from proteins to cells to complete organisms. These bioactive molecules can be therapeutic drug candidates, molecules for biotech, diagnostic or agronomic applications, or tools for basic research. Handling a large number of biological (genomic and post-genomic), chemical and experimental information, screening approaches cannot be envisaged without any electronic storage and mathematical treatment of the data. “Chemogenomics and Chemical Genetics” is an introductory manual presenting methods and concepts making up the basis for this recent discipline. This book is dedicated to biologists, chemists and computer scientist beginners. It is organized in brief, illustrated chapters with practical examples. Clear definitions of biological, chemical and IT concepts are given in a glossary section to help readers who are not familiar with one of these disciplines. "Chemogenomics and Chemical Genetics" should therefore be helpful for students (from Bachelor's degree level), technological platform engineers, and researchers in biology, chemistry, bioinformatics, cheminformatics, both in biotech and academic laboratories.
Bulletin Of The Atomic Scientists
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Author :
language : en
Publisher:
Release Date : 1972-10
Bulletin Of The Atomic Scientists written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972-10 with categories.
The Bulletin of the Atomic Scientists is the premier public resource on scientific and technological developments that impact global security. Founded by Manhattan Project Scientists, the Bulletin's iconic "Doomsday Clock" stimulates solutions for a safer world.
Inventory Of Federal Energy Related Environment And Safety Research For
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Author :
language : en
Publisher:
Release Date : 1980
Inventory Of Federal Energy Related Environment And Safety Research For written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Environmental engineering categories.
Inventory Of Federal Energy Related Environment And Safety Research For Fy 1979
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Author :
language : en
Publisher:
Release Date : 1980
Inventory Of Federal Energy Related Environment And Safety Research For Fy 1979 written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1980 with Environmental engineering categories.
Bulletin Of The Chemical Society Of Japan
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Author : Nihon Kagakkai
language : en
Publisher:
Release Date : 1996
Bulletin Of The Chemical Society Of Japan written by Nihon Kagakkai and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1996 with Chemistry categories.
Biomineralization
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Author : Stephen Mann
language : en
Publisher:
Release Date : 2001
Biomineralization written by Stephen Mann and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2001 with Science categories.
This book describes the principles and concepts of biomineralization and their application in the new field of biomimetic materials chemistry. The main focus is on the principles and concepts that arise from a chemical perspective of biomineralization. After surveying the major types of biominerals (chapter 2) the general principles of biomineralization are discussed (chapter 3), followed by a detailed description of the chemical aspects of biomineralization (chapter 4). The next four chapters are concerned with the process of biomineralization, including boundary-organized biomineralization (chapter 5), organic matrix-mediated biomineralization (chapter 6), morphogenesis (chapter 7) and biomineral tectonics (chapter 8). The final chapter describes how current knowledge of biomineralization is inspiring new biomimetic strategies in synthetic materials chemistry.
Side Reactions In Organic Synthesis
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Author : Florencio Zaragoza Dörwald
language : en
Publisher: John Wiley & Sons
Release Date : 2006-03-06
Side Reactions In Organic Synthesis written by Florencio Zaragoza Dörwald and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-06 with Science categories.
Most syntheses in the chemical research laboratory fail and usually require several attempts before proceeding satisfactorily. Failed syntheses are not only discouraging and frustrating, but also cost a lot of time and money. Many failures may, however, be avoided by understanding the structure-reactivity relationship of organic compounds. This textbook highlights the competing processes and limitations of the most important reactions used in organic synthesis. By allowing chemists to quickly recognize potential problems this book will help to improve their efficiency and success-rate. A must for every graduate student but also for every chemist in industry and academia. Contents: 1 Organic Synthesis: General Remarks 2 Stereoelectronic Effects and Reactivity 3 The Stability of Organic Compounds 4 Aliphatic Nucleophilic Substitutions: Problematic Electrophiles 5 The Alkylation of Carbanions 6 The Alkylation of Heteroatoms 7 The Acylation of Heteroatoms 8 Palladium-Catalyzed C-C Bond Formation 9 Cyclizations 10 Monofunctionalization of Symmetric Difunctional Substrates