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Conformational Proteomics Of Macromolecular Architecture


Conformational Proteomics Of Macromolecular Architecture
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Conformational Proteomics Of Macromolecular Architecture


Conformational Proteomics Of Macromolecular Architecture
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Author : R. Holland Cheng
language : en
Publisher: World Scientific
Release Date : 2004

Conformational Proteomics Of Macromolecular Architecture written by R. Holland Cheng and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Science categories.


Electronic version of the text of the same title with additional audio and video links.



Conformational Proteomics Of Macromolecular Architecture Approaching The Structure Of Large Molecular Assemblies And Their Mechanisms Of Action With Cd Rom


Conformational Proteomics Of Macromolecular Architecture Approaching The Structure Of Large Molecular Assemblies And Their Mechanisms Of Action With Cd Rom
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Author : R Holland Cheng
language : en
Publisher: World Scientific
Release Date : 2004-06-21

Conformational Proteomics Of Macromolecular Architecture Approaching The Structure Of Large Molecular Assemblies And Their Mechanisms Of Action With Cd Rom written by R Holland Cheng and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004-06-21 with Science categories.


Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which “activity” can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct. The biological implications of such adaptation are explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this important book presents cutting-edge knowledge in the various fields of structural proteomics of very large molecular assemblies, with the focus on their mechanisms of action.



Conformational Proteomics Of Macromolecular Architecture


Conformational Proteomics Of Macromolecular Architecture
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Author : Lena Hammar (ed)
language : en
Publisher: World Scientific Publishing Company
Release Date : 2004

Conformational Proteomics Of Macromolecular Architecture written by Lena Hammar (ed) and has been published by World Scientific Publishing Company this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Medical categories.


Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct. The biological implications of such adaptation are explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this important book presents cutting-edge knowledge in the various fields of structural proteomics of very large molecular assemblies, with the focus on their mechanisms of action.



Novel Developments In Cryo Em Of Biological Molecules


Novel Developments In Cryo Em Of Biological Molecules
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Author : Joachim Frank
language : en
Publisher: CRC Press
Release Date : 2023-10-06

Novel Developments In Cryo Em Of Biological Molecules written by Joachim Frank and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-10-06 with Science categories.


Cryo-EM, as it is currently practiced in many laboratories, is limited to the visualization of molecules that are in thermal equilibrium at the time before freezing. A further limitation is that the existing software does not fully exploit the information that is contained in the images of large ensembles of molecules in thermal equilibrium. This book is a collection of recent articles by the author, reprinted with introductions, and they mainly describe two novel methods in cryo-EM, one computational and the other experimental that requires the use of a microfluidic device. Both methods have the capacity to shed light on the dynamic behavior of biomolecules. Combined, they greatly expand the range of applications of cryo-EM. The book describes a successful approach in which, based on cryo-EM data, all states visited by the molecule in thermal equilibrium are mapped by manifold embedding—a method of geometric machine learning—and the energy landscape of the molecule is derived. It also discusses methods and biological results of time-resolved cryo-EM, following a reaction in a non-equilibrium system over a short period of time and resulting in the capture of short-lived states that have been inaccessible by standard methods of cryo-EM.



Environmental Health Perspectives


Environmental Health Perspectives
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Author :
language : en
Publisher:
Release Date : 1993

Environmental Health Perspectives written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993 with Environmental health categories.




Approaches To The Conformational Analysis Of Biopharmaceuticals


Approaches To The Conformational Analysis Of Biopharmaceuticals
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Author : Roger L. Lundblad
language : en
Publisher: CRC Press
Release Date : 2009-12-15

Approaches To The Conformational Analysis Of Biopharmaceuticals written by Roger L. Lundblad and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2009-12-15 with Medical categories.


The activity of many biopharmaceutical polymers is dependent on conformation, and the next several years will see increased interest in the conformational analysis of these polymers resulting from the development of biosimilar or "follow-on" biological products. While a wide variety of approaches to analysis exists, finding the most viable ones wou



Biomedical Applications Of Biophysics


Biomedical Applications Of Biophysics
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Author : Thomas Jue
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-08-18

Biomedical Applications Of Biophysics written by Thomas Jue and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-08-18 with Science categories.


In keeping with goal and style of the Handbook in Modern Biophysics series, the proposed book will maintain a chapter structure that contains two parts: concepts and biological application. The book also integrates all the chapters into a smooth, continuous discourse. The first and second chapters establish the mathematical methods and theoretical framework underpinning the different topics in the rest if the book. Other chapters will use the theoretical framework as a basis to discuss optical and NMR approaches. Each chapter will contain innovative didactic elements that facilitate teaching, self-study, and research preparation (key points, summary, exercise, references).



Nanotechnology Concepts Methodologies Tools And Applications


Nanotechnology Concepts Methodologies Tools And Applications
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Author : Management Association, Information Resources
language : en
Publisher: IGI Global
Release Date : 2014-02-28

Nanotechnology Concepts Methodologies Tools And Applications written by Management Association, Information Resources and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-02-28 with Technology & Engineering categories.


Over the past few decades, devices and technologies have been significantly miniaturized from one generation to the next, providing far more potential in a much smaller package. The smallest of these recently developed tools are miniscule enough to be invisible to the naked eye. Nanotechnology: Concepts, Methodologies, Tools, and Applications describes some of the latest advances in microscopic technologies in fields as diverse as biochemistry, materials science, medicine, and electronics. Through its investigation of theories, applications, and new developments in the nanotechnology field, this impressive reference source will serve as a valuable tool for researchers, engineers, academics, and students alike.



Aaron Klug A Long Way From Durban


Aaron Klug A Long Way From Durban
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Author : Kenneth C. Holmes
language : en
Publisher: Cambridge University Press
Release Date : 2017-02-09

Aaron Klug A Long Way From Durban written by Kenneth C. Holmes and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017-02-09 with Biography & Autobiography categories.


The life and work of Aaron Klug, Nobel prize winner and one of the pioneers of structural molecular biology.



Theoretical And Technological Advancements In Nanotechnology And Molecular Computation Interdisciplinary Gains


Theoretical And Technological Advancements In Nanotechnology And Molecular Computation Interdisciplinary Gains
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Author : MacLennan, Bruce
language : en
Publisher: IGI Global
Release Date : 2010-11-30

Theoretical And Technological Advancements In Nanotechnology And Molecular Computation Interdisciplinary Gains written by MacLennan, Bruce and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-11-30 with Computers categories.


Theoretical and Technological Advancements in Nanotechnology and Molecular Computation: Interdisciplinary Gains compiles research in areas where nanoscience and computer science meet. This book explores current and future trends that discus areas such as, cellular nanocomputers, DNA self-assembly, and the architectural design of a "nano-brain." The authors of each chapter have provided in-depth insight into the current state of research in nanotechnology and molecular computation as well as identified successful approaches, tools and methodologies in their research.