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Contemporary Approaches To Modelling Optimisation And Control Of Biotechnological Processes


Contemporary Approaches To Modelling Optimisation And Control Of Biotechnological Processes
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Contemporary Approaches To Modelling Optimisation And Control Of Biotechnological Processes


Contemporary Approaches To Modelling Optimisation And Control Of Biotechnological Processes
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Author :
language : en
Publisher:
Release Date : 2010

Contemporary Approaches To Modelling Optimisation And Control Of Biotechnological Processes written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010 with Biotechnology categories.




Modelling And Optimization Of Biotechnological Processes


Modelling And Optimization Of Biotechnological Processes
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Author : Lei Zhi Chen
language : en
Publisher: Springer
Release Date : 2007-07-04

Modelling And Optimization Of Biotechnological Processes written by Lei Zhi Chen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-04 with Technology & Engineering categories.


Mostindustrialbiotechnologicalprocessesareoperatedempirically.Oneofthe major di?culties of applying advanced control theories is the highly nonlinear nature of the processes. This book examines approaches based on arti?cial intelligencemethods,inparticular,geneticalgorithmsandneuralnetworks,for monitoring, modelling and optimization of fed-batch fermentation processes. The main aim of a process control is to maximize the ?nal product with minimum development and production costs. This book is interdisciplinary in nature, combining topics from biotechn- ogy, arti?cial intelligence, system identi?cation, process monitoring, process modelling and optimal control. Both simulation and experimental validation are performed in this study to demonstrate the suitability and feasibility of proposed methodologies. An online biomass sensor is constructed using a - current neural network for predicting the biomass concentration online with only three measurements (dissolved oxygen, volume and feed rate). Results show that the proposed sensor is comparable or even superior to other sensors proposed in the literature that use more than three measurements. Biote- nological processes are modelled by cascading two recurrent neural networks. It is found that neural models are able to describe the processes with high accuracy. Optimization of the ?nal product is achieved using modi?ed genetic algorithms to determine optimal feed rate pro?les. Experimental results of the corresponding production yields demonstrate that genetic algorithms are powerful tools for optimization of highly nonlinear systems. Moreover, a c- bination of recurrentneural networks and genetic algorithms provides a useful and cost-e?ective methodology for optimizing biotechnological processes.



Research Methods Concepts Methodologies Tools And Applications


Research Methods Concepts Methodologies Tools And Applications
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Author : Management Association, Information Resources
language : en
Publisher: IGI Global
Release Date : 2015-01-31

Research Methods Concepts Methodologies Tools And Applications written by Management Association, Information Resources and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-01-31 with Science categories.


Across a variety of disciplines, data and statistics form the backbone of knowledge. To ensure the reliability and validity of data, appropriate measures must be taken in conducting studies and reporting findings. Research Methods: Concepts, Methodologies, Tools, and Applications compiles chapters on key considerations in the management, development, and distribution of data. With its focus on both fundamental concepts and advanced topics, this multi-volume reference work will be a valuable addition to researchers, scholars, and students of science, mathematics, and engineering.



Handbook Of Research On Novel Soft Computing Intelligent Algorithms


Handbook Of Research On Novel Soft Computing Intelligent Algorithms
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Author : Pandian Vasant
language : en
Publisher: IGI Global
Release Date : 2013-08-31

Handbook Of Research On Novel Soft Computing Intelligent Algorithms written by Pandian Vasant and has been published by IGI Global this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-08-31 with Technology & Engineering categories.


"This book explores emerging technologies and best practices designed to effectively address concerns inherent in properly optimizing advanced systems, demonstrating applications in areas such as bio-engineering, space exploration, industrial informatics, information security, and nuclear and renewable energies"--Provided by publisher.



Measurement Monitoring Modelling And Control Of Bioprocesses


Measurement Monitoring Modelling And Control Of Bioprocesses
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Author : Carl-Fredrik Mandenius
language : en
Publisher: Springer
Release Date : 2014-07-08

Measurement Monitoring Modelling And Control Of Bioprocesses written by Carl-Fredrik Mandenius and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Science categories.


Automated Measurement and Monitoring of Bioprocesses: Key Elements of the M3C Strategy, by Bernhard Sonnleitner Automatic Control of Bioprocesses, by Marc Stanke, Bernd Hitzmann An Advanced Monitoring Platform for Rational Design of Recombinant Processes, by G. Striedner, K. Bayer Modelling Approaches for Bio-Manufacturing Operations, by Sunil Chhatre Extreme Scale-Down Approaches for Rapid Chromatography Column Design and Scale-Up During Bioprocess Development, by Sunil Chhatre Applying Mechanistic Models in Bioprocess Development, by Rita Lencastre Fernandes, Vijaya Krishna Bodla, Magnus Carlquist, Anna-Lena Heins, Anna Eliasson Lantz, Gürkan Sin and Krist V. Gernaey Multivariate Data Analysis for Advancing the Interpretation of Bioprocess Measurement and Monitoring Data, by Jarka Glassey Design of Pathway-Level Bioprocess Monitoring and Control Strategies Supported by Metabolic Networks, by Inês A. Isidro, Ana R. Ferreira, João J. Clemente, António E. Cunha, João M. L. Dias, Rui Oliveira Knowledge Management and Process Monitoring of Pharmaceutical Processes in the Quality by Design Paradigm, by Anurag S Rathore, Anshuman Bansal, Jaspinder Hans The Choice of Suitable Online Analytical Techniques and Data Processing for Monitoring of Bioprocesses, by Ian Marison, Siobhán Hennessy, Róisín Foley, Moira Schuler, Senthilkumar Sivaprakasam, Brian Freeland



Research In Computer Science In The Bulgarian Academy Of Sciences


Research In Computer Science In The Bulgarian Academy Of Sciences
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Author : Krassimir T. Atanassov
language : en
Publisher: Springer Nature
Release Date : 2021-07-19

Research In Computer Science In The Bulgarian Academy Of Sciences written by Krassimir T. Atanassov and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-07-19 with Technology & Engineering categories.


This book is a collection of papers devoted to the emergence and development in Bulgarian Academy of Sciences of some of the areas of informatics, including artificial intelligence. The papers are prepared by specialists from the Academy, some of whom are among the founders of these scientific and application areas in Bulgaria and in some cases – in the world. The book is interesting for specialists in informatics and computer science and researchers in history of sciences.



Modelling And Control Of Biotechnological Processes


Modelling And Control Of Biotechnological Processes
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Author : A. Johnson
language : en
Publisher: Elsevier
Release Date : 2014-05-17

Modelling And Control Of Biotechnological Processes written by A. Johnson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-17 with Technology & Engineering categories.


Modelling and Control of Biotechnological Processes contains the proceedings of the International Federation of Automatic Control's First Symposium on Modeling and Control of Biotechnological Processes held in Noordwijkerhout, The Netherlands, on December 11-13, 1985. The papers explore modeling and control of biotechnological processes such as fermentation and biological wastewater treatment. This book consists of 37 chapters divided into 11 sections and begins with a discussion on the control of fermentation processes; modeling of biotechnical processes; and application of measurement and estimation techniques to biotechnology. The following sections focus on adaptive control theory, applications of adaptive control, and control and modeling of bioreactors. The reader is also introduced to measurement techniques and sensors, with emphasis on pyrolysis mass spectrometry; rapid bioelectrochemical methods; and a self-tuning controller for multiloop controlled fed-batch fermentation. The remaining sections deal with parameter identification and estimation; Kalman filtering techniques; optimization of production processes; modeling of microkinetics; and optimization theory. This monograph will be of interest to researchers and practitioners in the field of biotechnology.



Control Of Biotechnological Processes


Control Of Biotechnological Processes
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Author : Maya Ignatova
language : en
Publisher: LAP Lambert Academic Publishing
Release Date : 2011-04

Control Of Biotechnological Processes written by Maya Ignatova and has been published by LAP Lambert Academic Publishing this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-04 with categories.


In the book, contemporary approach for monitoring and control of biotechnological processes on new formalization of process kinetics is presented. The new idea is the substrate kinetics to be considered as fully unknown and time-varying. This new formalization allows avoiding widespread conception for bioprocess models with constant yield coefficients. In practice, the model coefficients of such processes with nonlinear nature and low level of reproducibility are time-varying. Different applications and modifications of the proposed approach are presented. The modifications ensue from the process characteristics - process target product and available information. The present book generalizes the long authors' experience with different bioprocesses in food and pharmaceutical industries, in wastewater treatment as well as for bio-fuels production from renewable sources. It is intended as a graduate level text for students in bioengineering as well as a reference text for scientists and engineers involved in bioprocess control design.



Modelling And Adaptive Control Of Biotechnological Processes


Modelling And Adaptive Control Of Biotechnological Processes
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Author : Marie-France Weirig
language : en
Publisher:
Release Date : 1998

Modelling And Adaptive Control Of Biotechnological Processes written by Marie-France Weirig and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Biotechnological process control categories.




Digital Twins


Digital Twins
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Author : Christoph Herwig
language : en
Publisher: Springer Nature
Release Date : 2021-04-25

Digital Twins written by Christoph Herwig and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-25 with Technology & Engineering categories.


This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book focuses on the application of digital twins in various contexts, e.g. computer-aided experimental design, seed train prediction, and lifeline analysis. Covering fundamentals as well as applications, the two volumes offers the ideal introduction to the topic for researchers in academy and industry alike.