Modelling And Optimization Of Biotechnological Processes
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Modelling And Optimization Of Biotechnological Processes
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Author : Lei Zhi Chen
language : en
Publisher: Springer
Release Date : 2007-07-04
Modelling And Optimization Of Biotechnological Processes written by Lei Zhi Chen and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-07-04 with Technology & Engineering categories.
Mostindustrialbiotechnologicalprocessesareoperatedempirically.Oneofthe major di?culties of applying advanced control theories is the highly nonlinear nature of the processes. This book examines approaches based on arti?cial intelligencemethods,inparticular,geneticalgorithmsandneuralnetworks,for monitoring, modelling and optimization of fed-batch fermentation processes. The main aim of a process control is to maximize the ?nal product with minimum development and production costs. This book is interdisciplinary in nature, combining topics from biotechn- ogy, arti?cial intelligence, system identi?cation, process monitoring, process modelling and optimal control. Both simulation and experimental validation are performed in this study to demonstrate the suitability and feasibility of proposed methodologies. An online biomass sensor is constructed using a - current neural network for predicting the biomass concentration online with only three measurements (dissolved oxygen, volume and feed rate). Results show that the proposed sensor is comparable or even superior to other sensors proposed in the literature that use more than three measurements. Biote- nological processes are modelled by cascading two recurrent neural networks. It is found that neural models are able to describe the processes with high accuracy. Optimization of the ?nal product is achieved using modi?ed genetic algorithms to determine optimal feed rate pro?les. Experimental results of the corresponding production yields demonstrate that genetic algorithms are powerful tools for optimization of highly nonlinear systems. Moreover, a c- bination of recurrentneural networks and genetic algorithms provides a useful and cost-e?ective methodology for optimizing biotechnological processes.
Modelling And Optimization Of Biotechnological Processes
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Author : Leizhi Chen
language : en
Publisher:
Release Date : 2004
Modelling And Optimization Of Biotechnological Processes written by Leizhi Chen and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Animal cell biotechnology categories.
Development Of A Generalized Process Model For Optimization Of Biotechnological Processes
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Author : Simone Brüning
language : en
Publisher:
Release Date : 2017
Development Of A Generalized Process Model For Optimization Of Biotechnological Processes written by Simone Brüning and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2017 with categories.
Supervision Control And Optimization Of Biotechnological Processes
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Author : Rui Manuel Freitas Oliveira
language : en
Publisher:
Release Date : 1998
Supervision Control And Optimization Of Biotechnological Processes written by Rui Manuel Freitas Oliveira and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with categories.
Modelling And Control Of Biotechnological Processes
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Author : A. Johnson
language : en
Publisher: Elsevier
Release Date : 2014-05-17
Modelling And Control Of Biotechnological Processes written by A. Johnson and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-17 with Technology & Engineering categories.
Modelling and Control of Biotechnological Processes contains the proceedings of the International Federation of Automatic Control's First Symposium on Modeling and Control of Biotechnological Processes held in Noordwijkerhout, The Netherlands, on December 11-13, 1985. The papers explore modeling and control of biotechnological processes such as fermentation and biological wastewater treatment. This book consists of 37 chapters divided into 11 sections and begins with a discussion on the control of fermentation processes; modeling of biotechnical processes; and application of measurement and estimation techniques to biotechnology. The following sections focus on adaptive control theory, applications of adaptive control, and control and modeling of bioreactors. The reader is also introduced to measurement techniques and sensors, with emphasis on pyrolysis mass spectrometry; rapid bioelectrochemical methods; and a self-tuning controller for multiloop controlled fed-batch fermentation. The remaining sections deal with parameter identification and estimation; Kalman filtering techniques; optimization of production processes; modeling of microkinetics; and optimization theory. This monograph will be of interest to researchers and practitioners in the field of biotechnology.
Stochastic Global Optimization Methods And Applications To Chemical Biochemical Pharmaceutical And Environmental Processes
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Author : Ch. Venkateswarlu
language : en
Publisher: Elsevier
Release Date : 2019-11-18
Stochastic Global Optimization Methods And Applications To Chemical Biochemical Pharmaceutical And Environmental Processes written by Ch. Venkateswarlu and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-11-18 with Technology & Engineering categories.
Stochastic global optimization methods and applications to chemical, biochemical, pharmaceutical and environmental processes presents various algorithms that include the genetic algorithm, simulated annealing, differential evolution, ant colony optimization, tabu search, particle swarm optimization, artificial bee colony optimization, and cuckoo search algorithm. The design and analysis of these algorithms is studied by applying them to solve various base case and complex optimization problems concerning chemical, biochemical, pharmaceutical, and environmental engineering processes. Design and implementation of various classical and advanced optimization strategies to solve a wide variety of optimization problems makes this book beneficial to graduate students, researchers, and practicing engineers working in multiple domains. This book mainly focuses on stochastic, evolutionary, and artificial intelligence optimization algorithms with a special emphasis on their design, analysis, and implementation to solve complex optimization problems and includes a number of real applications concerning chemical, biochemical, pharmaceutical, and environmental engineering processes. Presents various classical, stochastic, evolutionary, and artificial intelligence optimization algorithms for the benefit of the audience in different domains Outlines design, analysis, and implementation of optimization strategies to solve complex optimization problems of different domains Highlights numerous real applications concerning chemical, biochemical, pharmaceutical, and environmental engineering processes
Digital Twins
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Author : Christoph Herwig
language : en
Publisher: Springer Nature
Release Date : 2021-04-25
Digital Twins written by Christoph Herwig and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-04-25 with Technology & Engineering categories.
This is the second of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization. Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. This book focuses on the application of digital twins in various contexts, e.g. computer-aided experimental design, seed train prediction, and lifeline analysis. Covering fundamentals as well as applications, the two volumes offers the ideal introduction to the topic for researchers in academy and industry alike.
Modelling And Adaptive Control Of Biotechnological Processes
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Author : Marie-France Weirig
language : en
Publisher:
Release Date : 1998
Modelling And Adaptive Control Of Biotechnological Processes written by Marie-France Weirig and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1998 with Biotechnological process control categories.
Computer Applications In Fermentation Technology Modelling And Control Of Biotechnological Processes
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Author : N. M. Fish
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06
Computer Applications In Fermentation Technology Modelling And Control Of Biotechnological Processes written by N. M. Fish and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Science categories.
Richard Fox Chairman, Scientific Programme Committee Between 25th and 29th September, 1988, 243 people who either apply or research the use of computers in fermentation gathered together at Robinson College, Cambridge, UK. They came from 30 countries. The conference brought together two traditions. Firstly, it continued the series on Computer Applications in Fermentation Technology (ICCAFT) inaugurated by Henri Blanchere in Dijon in 1973 and carried forward in Philadelphia and Manchester. Secondly, it brought the expertise of the many members of the International Federation of Automatic Control (IFAC), who focused their attention on biotechnology at Noordwijkerhout in the Netherlands in December, 1985. I am happy to say that the tradition carries on and a successor meeting will hopefully take place in the USA in 1991. If you find these proceedings useful or stimulating, then we hope to see you there. We set out to make ICCAFT4 a close-knit friendly conference. We housed all who cared to in Robinson College itself and organised no parallel sessions. Because we, the organisers, experience difficulty with the jargon of our colleagues from other disciplines, we asked Bruce Beck to present a breakfast tutorial on modern control and modelling techniques, and we set up informal panel discussions after dinner on two evenings. Neville Fish chaired a forum on the microbiological principles behind models, while Professors Derek Linkens and Ron Leigh led a discussion on expert systems in control.
Optimization And Control Of Biotechnical Processes Using Mechanistic Mathematical Models
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Author : Jan van Breugel
language : en
Publisher:
Release Date : 1986
Optimization And Control Of Biotechnical Processes Using Mechanistic Mathematical Models written by Jan van Breugel and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1986 with Automatic control categories.