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Contemporary Biostatistics With Biopharmaceutical Applications


Contemporary Biostatistics With Biopharmaceutical Applications
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Contemporary Biostatistics With Biopharmaceutical Applications


Contemporary Biostatistics With Biopharmaceutical Applications
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Author : Lanju Zhang
language : en
Publisher: Springer
Release Date : 2019-07-11

Contemporary Biostatistics With Biopharmaceutical Applications written by Lanju Zhang and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-11 with Medical categories.


This edited volume presents current research in biostatistics with emphasis on biopharmaceutical applications. Featuring contributions presented at the 2017 ICSA Applied Statistics Symposium held in Chicago, IL on June 25 to 28, 2017, this book explores timely topics that have a high potential impact on statistical methodology and future research in biostatistics and biopharmaceuticals. The theme of this conference was Statistics for a New Generation: Challenges and Opportunities, in recognition of the advent of a new generation of statisticians. The conference attracted statisticians working in academia, government, and industry; domestic and international statisticians. From the conference, the editors selected 28 high-quality presentations and invited the speakers to prepare full chapters for this book. These contributions are divided into four parts: Part I Biostatistical Methodology, Part II Statistical Genetics and Bioinformatics, Part III Regulatory Statistics, and Part IV Biopharmaceutical Research and Applications. Featuring contributions on topics such as statistics in genetics, bioinformatics, biostatistical methodology, and statistical computing, this book is beneficial to researchers, academics, practitioners and policy makers in biostatistics and biopharmaceuticals.



Contemporary Biostatistics With Biopharmaceutical Applications


Contemporary Biostatistics With Biopharmaceutical Applications
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Author : Lanju Zhang
language : en
Publisher:
Release Date : 2019

Contemporary Biostatistics With Biopharmaceutical Applications written by Lanju Zhang and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.


This edited volume presents current research in biostatistics with emphasis on biopharmaceutical applications. Featuring contributions presented at the 2017 ICSA Applied Statistics Symposium held in Chicago, IL on June 25 to 28, 2017, this book explores timely topics that have a high potential impact on statistical methodology and future research in biostatistics and biopharmaceuticals. The theme of this conference was Statistics for A New Generation: Challenges and Opportunities, in recognition of the advent of a new generation of statisticians. The conference attracted statisticians working in academia, government, and industry; domestic and international statisticians. From the conference, the editors selected 28 high-quality presentations and invited the speakers to prepare full chapters for this book. These contributions are divided into four parts: Part I Biostatistical Methodology, Part II Statistical Genetics and Bioinformatics, Part III Regulatory Statistics, and Part IV Biopharmaceutical Research and Applications. Featuring contributions on topics such as statistics in genetics, bioinformatics, biostatistical methodology, and statistical computing, this book is beneficial to researchers, academics, practitioners and policy makers in biostatistics and biopharmaceuticals.



Clinical Trial Biostatistics And Biopharmaceutical Applications


Clinical Trial Biostatistics And Biopharmaceutical Applications
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Author : Walter R. Young
language : en
Publisher: CRC Press
Release Date : 2014-11-20

Clinical Trial Biostatistics And Biopharmaceutical Applications written by Walter R. Young and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-11-20 with Mathematics categories.


Since 1945, "The Annual Deming Conference on Applied Statistics" has been an important event in the statistics profession. In Clinical Trial Biostatistics and Biopharmaceutical Applications, prominent speakers from past Deming conferences present novel biostatistical methodologies in clinical trials as well as up-to-date biostatistical applications



Multivariate Time Series Analysis And Applications


Multivariate Time Series Analysis And Applications
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Author : William W. S. Wei
language : en
Publisher: John Wiley & Sons
Release Date : 2019-03-18

Multivariate Time Series Analysis And Applications written by William W. S. Wei and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-03-18 with Mathematics categories.


An essential guide on high dimensional multivariate time series including all the latest topics from one of the leading experts in the field Following the highly successful and much lauded book, Time Series Analysis—Univariate and Multivariate Methods, this new work by William W.S. Wei focuses on high dimensional multivariate time series, and is illustrated with numerous high dimensional empirical time series. Beginning with the fundamentalconcepts and issues of multivariate time series analysis,this book covers many topics that are not found in general multivariate time series books. Some of these are repeated measurements, space-time series modelling, and dimension reduction. The book also looks at vector time series models, multivariate time series regression models, and principle component analysis of multivariate time series. Additionally, it provides readers with information on factor analysis of multivariate time series, multivariate GARCH models, and multivariate spectral analysis of time series. With the development of computers and the internet, we have increased potential for data exploration. In the next few years, dimension will become a more serious problem. Multivariate Time Series Analysis and its Applications provides some initial solutions, which may encourage the development of related software needed for the high dimensional multivariate time series analysis. Written by bestselling author and leading expert in the field Covers topics not yet explored in current multivariate books Features classroom tested material Written specifically for time series courses Multivariate Time Series Analysis and its Applications is designed for an advanced time series analysis course. It is a must-have for anyone studying time series analysis and is also relevant for students in economics, biostatistics, and engineering.



Biostatistics In Biopharmaceutical Research And Development


Biostatistics In Biopharmaceutical Research And Development
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Author : Ding-Geng Chen
language : en
Publisher: Springer Nature
Release Date : 2024-12-24

Biostatistics In Biopharmaceutical Research And Development written by Ding-Geng Chen and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-12-24 with Mathematics categories.


The Deming Conference on Applied Statistics has long been deemed an influential event in the biostatistics and biopharmaceutical profession. It provides learning experience on recent developments in statistical methodologies in biopharmaceutical applications and FDA regulations. This book honors 80 years of contributions and dedication of the Deming Conference in biostatistics, and biopharmaceutical clinical trial methodology and applications. All chapters are contributed by world-class and prominent Deming speakers, who've contributed their cutting-edge research and developments to the community. Volume 2 covers Biomarkers in Drug Development, Time-To-Event Data Analysis and Methods, and emerging development in biopharmaceutical biostatistics. This book aims to booster research, education, and training in biostatistics and in biopharmaceutical research and development.



Biopharmaceutical Applied Statistics Symposium


Biopharmaceutical Applied Statistics Symposium
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Author : Karl E. Peace
language : en
Publisher: Springer
Release Date : 2018-09-03

Biopharmaceutical Applied Statistics Symposium written by Karl E. Peace and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2018-09-03 with Medical categories.


This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments – particularly biopharmaceutical clinical trials. The papers were selected from invited presentations at the Biopharmaceutical Applied Statistics Symposium (BASS), which was founded by the first Editor in 1994 and has since become the premier international conference in biopharmaceutical statistics. The primary aims of the BASS are: 1) to raise funding to support graduate students in biostatistics programs, and 2) to provide an opportunity for professionals engaged in pharmaceutical drug research and development to share insights into solving the problems they encounter. The BASS book series is initially divided into three volumes addressing: 1) Design of Clinical Trials; 2) Biostatistical Analysis of Clinical Trials; and 3) Pharmaceutical Applications. This book is the third of the 3-volume book series. The topics covered include: Targeted Learning of Optimal Individualized Treatment Rules under Cost Constraints, Uses of Mixture Normal Distribution in Genomics and Otherwise, Personalized Medicine – Design Considerations, Adaptive Biomarker Subpopulation and Tumor Type Selection in Phase III Oncology Trials, High Dimensional Data in Genomics; Synergy or Additivity - The Importance of Defining the Primary Endpoint, Full Bayesian Adaptive Dose Finding Using Toxicity Probability Interval (TPI), Alpha-recycling for the Analyses of Primary and Secondary Endpoints of Clinical Trials, Expanded Interpretations of Results of Carcinogenicity Studies of Pharmaceuticals, Randomized Clinical Trials for Orphan Drug Development, Mediation Modeling in Randomized Trials with Non-normal Outcome Variables, Statistical Considerations in Using Images in Clinical Trials, Interesting Applications over 30 Years of Consulting, Uncovering Fraud, Misconduct and OtherData Quality Issues in Clinical Trials, Development and Evaluation of High Dimensional Prognostic Models, and Design and Analysis of Biosimilar Studies.



Modern Issues And Methods In Biostatistics


Modern Issues And Methods In Biostatistics
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Author : Mark Chang
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-07-15

Modern Issues And Methods In Biostatistics written by Mark Chang and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-07-15 with Medical categories.


Classic biostatistics, a branch of statistical science, has as its main focus the applications of statistics in public health, the life sciences, and the pharmaceutical industry. Modern biostatistics, beyond just a simple application of statistics, is a confluence of statistics and knowledge of multiple intertwined fields. The application demands, the advancements in computer technology, and the rapid growth of life science data (e.g., genomics data) have promoted the formation of modern biostatistics. There are at least three characteristics of modern biostatistics: (1) in-depth engagement in the application fields that require penetration of knowledge across several fields, (2) high-level complexity of data because they are longitudinal, incomplete, or latent because they are heterogeneous due to a mixture of data or experiment types, because of high-dimensionality, which may make meaningful reduction impossible, or because of extremely small or large size; and (3) dynamics, the speed of development in methodology and analyses, has to match the fast growth of data with a constantly changing face. This book is written for researchers, biostatisticians/statisticians, and scientists who are interested in quantitative analyses. The goal is to introduce modern methods in biostatistics and help researchers and students quickly grasp key concepts and methods. Many methods can solve the same problem and many problems can be solved by the same method, which becomes apparent when those topics are discussed in this single volume.



Introductory Biostatistics For The Health Sciences


Introductory Biostatistics For The Health Sciences
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Author : Michael R. Chernick
language : en
Publisher: John Wiley & Sons
Release Date : 2003-06-24

Introductory Biostatistics For The Health Sciences written by Michael R. Chernick and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2003-06-24 with Mathematics categories.


"Introductory Biostatistics for the Health Sciences" ist eine fundierte Einführung in die Biostatistik und ihre Anwendungsgebiete. Der Band richtet sich vorwiegend an Mediziner und Statistiker. Theorie und Praxis stehen im ausgewogenen Verhältnis, d.h. praktische Anwendungen werden, wo nötig, durch den theoretischen Hintergrund ergänzt. Der Schwerpunkt liegt eindeutig auf der praktischen Anwendung. Der Band geht auch auf jüngste Fortschritte bei der Bootstrap-, Outlier- und Meta-Analyse ein, Themen, die in der Regel in Konkurrenzwerken, nicht behandelt werden. Mit einer Fülle von Übungsaufgaben. Auch Statistiksoftware wird ausführlich besprochen.



Current Index To Statistics Applications Methods And Theory


Current Index To Statistics Applications Methods And Theory
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Author :
language : en
Publisher:
Release Date : 1994

Current Index To Statistics Applications Methods And Theory written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1994 with Mathematical statistics categories.


The Current Index to Statistics (CIS) is a bibliographic index of publications in statistics, probability, and related fields.



Mathematical And Statistical Skills In The Biopharmaceutical Industry


Mathematical And Statistical Skills In The Biopharmaceutical Industry
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Author : Arkadiy Pitman
language : en
Publisher: CRC Press
Release Date : 2019-07-15

Mathematical And Statistical Skills In The Biopharmaceutical Industry written by Arkadiy Pitman and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-07-15 with Business & Economics categories.


Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach describes a philosophy of efficient problem solving showcased using examples pertinent to the biostatistics function in clinical drug development. It was written to share a quintessence of the authors’ experiences acquired during many years of relevant work in the biopharmaceutical industry. The book will be useful will be useful for biopharmaceutical industry statisticians at different seniority levels and for graduate students who consider a biostatistics-related career in this industry. Features: Describes a system of principles for pragmatic problem solving in clinical drug development. Discusses differences in the work of a biostatistician in small pharma and big pharma. Explains the importance/relevance of statistical programming and data management for biostatistics and necessity for integration on various levels. Describes some useful statistical background that can be capitalized upon in the drug development enterprise. Explains some hot topics and current trends in biostatistics in simple, non-technical terms. Discusses incompleteness of any system of standard operating procedures, rules and regulations. Provides a classification of scoring systems and proposes a novel approach for evaluation of the safety outcome for a completed randomized clinical trial. Presents applications of the problem solving philosophy in a highly problematic transfusion field where many investigational compounds have failed. Discusses realistic planning of open-ended projects.