Continuum Modeling In Mechanobiology
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Continuum Modeling In Mechanobiology
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Author : Larry A. Taber
language : en
Publisher: Springer Nature
Release Date : 2020-06-15
Continuum Modeling In Mechanobiology written by Larry A. Taber and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-15 with Technology & Engineering categories.
This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.
Biomechanics Trends In Modeling And Simulation
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Author : Gerhard A. Holzapfel
language : en
Publisher: Springer
Release Date : 2016-09-14
Biomechanics Trends In Modeling And Simulation written by Gerhard A. Holzapfel and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-14 with Technology & Engineering categories.
The book presents a state-of-the-art overview of biomechanical and mechanobiological modeling and simulation of soft biological tissues. Seven well-known scientists working in that particular field discuss topics such as biomolecules, networks and cells as well as failure, multi-scale, agent-based, bio-chemo-mechanical and finite element models appropriate for computational analysis. Applications include arteries, the heart, vascular stents and valve implants as well as adipose, brain, collagenous and engineered tissues. The mechanics of the whole cell and sub-cellular components as well as the extracellular matrix structure and mechanotransduction are described. In particular, the formation and remodeling of stress fibers, cytoskeletal contractility, cell adhesion and the mechanical regulation of fibroblast migration in healing myocardial infarcts are discussed. The essential ingredients of continuum mechanics are provided. Constitutive models of fiber-reinforced materials with an emphasis on arterial walls and the myocardium are discussed and the important influence of residual stresses on material response emphasized. The mechanics and function of the heart, the brain and adipose tissues are discussed as well. Particular attention is focused on microstructural and multi-scale modeling, finite element implementation and simulation of cells and tissues.
Multiscale Modeling In Biomechanics And Mechanobiology
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Author : Suvranu De
language : en
Publisher: Springer
Release Date : 2014-10-10
Multiscale Modeling In Biomechanics And Mechanobiology written by Suvranu De and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Technology & Engineering categories.
Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.
Modeling Biomaterials
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Author : Josef Málek
language : en
Publisher: Springer Nature
Release Date : 2022-01-21
Modeling Biomaterials written by Josef Málek and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-01-21 with Mathematics categories.
The investigation of the role of mechanical and mechano-chemical interactions in cellular processes and tissue development is a rapidly growing research field in the life sciences and in biomedical engineering. Quantitative understanding of this important area in the study of biological systems requires the development of adequate mathematical models for the simulation of the evolution of these systems in space and time. Since expertise in various fields is necessary, this calls for a multidisciplinary approach. This edited volume connects basic physical, biological, and physiological concepts to methods for the mathematical modeling of various materials by pursuing a multiscale approach, from subcellular to organ and system level. Written by active researchers, each chapter provides a detailed introduction to a given field, illustrates various approaches to creating models, and explores recent advances and future research perspectives. Topics covered include molecular dynamics simulations of lipid membranes, phenomenological continuum mechanics of tissue growth, and translational cardiovascular modeling. Modeling Biomaterials will be a valuable resource for both non-specialists and experienced researchers from various domains of science, such as applied mathematics, biophysics, computational physiology, and medicine.
Continuum Mechanics
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Author : Franco M. Capaldi
language : en
Publisher:
Release Date : 2012
Continuum Mechanics written by Franco M. Capaldi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012 with Continuum mechanics categories.
Designed for continuum mechanics courses and features both the theoretical framework and numerical methods required to model continuous material behaviour.
Computer Models In Biomechanics
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Author : Gerhard Holzapfel
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-10-17
Computer Models In Biomechanics written by Gerhard Holzapfel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-10-17 with Technology & Engineering categories.
This book contains a collection of papers that were presented at the IUTAM Symposium on “Computer Models in Biomechanics: From Nano to Macro” held at Stanford University, California, USA, from August 29 to September 2, 2011. It contains state-of-the-art papers on: - Protein and Cell Mechanics: coarse-grained model for unfolded proteins, collagen-proteoglycan structural interactions in the cornea, simulations of cell behavior on substrates - Muscle Mechanics: modeling approaches for Ca2+–regulated smooth muscle contraction, smooth muscle modeling using continuum thermodynamical frameworks, cross-bridge model describing the mechanoenergetics of actomyosin interaction, multiscale skeletal muscle modeling - Cardiovascular Mechanics: multiscale modeling of arterial adaptations by incorporating molecular mechanisms, cardiovascular tissue damage, dissection properties of aortic aneurysms, intracranial aneurysms, electromechanics of the heart, hemodynamic alterations associated with arterial remodeling following aortic coarctation, patient-specific surgery planning for the Fontan procedure - Multiphasic Models: solutes in hydrated biological tissues, reformulation of mixture theory-based poroelasticity for interstitial tissue growth, tumor therapies of brain tissue, remodeling of microcirculation in liver lobes, reactions, mass transport and mechanics of tumor growth, water transport modeling in the brain, crack modeling of swelling porous media - Morphogenesis, Biological Tissues and Organs: mechanisms of brain morphogenesis, micromechanical modeling of anterior cruciate ligaments, mechanical characterization of the human liver, in vivo validation of predictive models for bone remodeling and mechanobiology, bridging scales in respiratory mechanics
Multiscale Computer Modeling In Biomechanics And Biomedical Engineering
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Author : Amit Gefen
language : en
Publisher: Springer Science & Business Media
Release Date : 2014-07-08
Multiscale Computer Modeling In Biomechanics And Biomedical Engineering written by Amit Gefen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-07-08 with Technology & Engineering categories.
This book reviews the state-of-the-art in multiscale computer modeling, in terms of both accomplishments and challenges. The information in the book is particularly useful for biomedical engineers, medical physicists and researchers in systems biology, mathematical biology, micro-biomechanics and biomaterials who are interested in how to bridge between traditional biomedical engineering work at the organ and tissue scales, and the newer arenas of cellular and molecular bioengineering.
Continuum Mechanical Modelling Across Scales
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Author : Christian Bleiler
language : en
Publisher:
Release Date : 2021
Continuum Mechanical Modelling Across Scales written by Christian Bleiler and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021 with categories.
Modern Modeling Of Continuum Phenomena
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Author : Richard C. DiPrima
language : en
Publisher: American Mathematical Soc.
Release Date : 1977-12-31
Modern Modeling Of Continuum Phenomena written by Richard C. DiPrima and has been published by American Mathematical Soc. this book supported file pdf, txt, epub, kindle and other format this book has been release on 1977-12-31 with Science categories.
A First Course In Continuum Mechanics
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Author : Oscar Gonzalez
language : en
Publisher: Cambridge University Press
Release Date : 2008-01-17
A First Course In Continuum Mechanics written by Oscar Gonzalez and has been published by Cambridge University Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-01-17 with Science categories.
The modeling and simulation of fluids, solids and other materials with significant coupling and thermal effects is becoming an increasingly important area of study in applied mathematics and engineering. Necessary for such studies is a fundamental understanding of the basic principles of continuum mechanics and thermodynamics. This book is a clear introduction to these principles. It is designed for a one- or two-quarter course for advanced undergraduate and beginning graduate students in the mathematical and engineering sciences, and is based on over nine years of teaching experience. It is also sufficiently self-contained for use outside a classroom environment. Prerequisites include a basic knowledge of linear algebra, multivariable calculus, differential equations and physics. The authors begin by explaining tensor algebra and calculus in three-dimensional Euclidean space. Using both index and coordinate-free notation, they introduce the basic axioms of continuum mechanics pertaining to mass, force, motion, temperature, energy and entropy, and the concepts of frame-indifference and material constraints. They devote four chapters to different theories of fluids and solids, and, unusually at this level, they consider both isothermal and thermal theories in detail. The book contains a wealth of exercises that support the theory and illustrate various applications. Full solutions to odd-numbered exercises are given at the end of each chapter and a complete solutions manual for all exercises is available to instructors upon request. Each chapter also contains a bibliography with references covering different presentations, further applications and numerical aspects of the theory. Book jacket.