Continuum Modeling In Mechanobiology

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Continuum Modeling In Mechanobiology

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Author : Larry A. Taber
language : en
Publisher: Springer Nature
Release Date : 2020-06-15

Continuum Modeling In Mechanobiology written by Larry A. Taber and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-06-15 with Technology & Engineering categories.

This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

Multiscale Modeling In Biomechanics And Mechanobiology

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Author : Suvranu De
language : en
Publisher: Springer
Release Date : 2014-10-10

Multiscale Modeling In Biomechanics And Mechanobiology written by Suvranu De and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-10-10 with Technology & Engineering categories.

Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Mechanobiology

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Author : Glen L. Niebur
language : en
Publisher: Elsevier
Release Date : 2019-12-01

Mechanobiology written by Glen L. Niebur and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-12-01 with Science categories.

Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. - Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli - Provides a review of diseases with known or purported mechanobiological underpinnings - Includes the role of mechanobiology in tissue engineering and regenerative medicine - Covers experimental methods to capture mechanobiological phenomena

Modeling For All Scales

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Author : Howard T. Odum
language : en
Publisher: Elsevier
Release Date : 2000-02-03

Modeling For All Scales written by Howard T. Odum and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2000-02-03 with Science categories.

All manner of models are used to describe, simulate, extrapolate, and ultimately understand the function of dynamic systems. These sorts of models are usually based upon a mathematical foundation that can be difficult to manipulate especially for students. Modeling for All Scales uses object-oriented programming to erect and evaluate the efficacy of models of small, intermediate and large scale systems. Such models allow users to employ intuitively based symbols and a systems ecology approach. The authors have been leaders in the systems ecology community and have originated much of the scientific vocabulary of the field. After introducing modeling and its benefits, there is a series of chapters detailing the more particular elements of successful simulation. There follows another series of chapters, each devoted to models of different sorts of systems. Small scale models of growth, competition, and evolution give way, successively, to larger and larger scale models such as international trade and the global geobiosphere. Anyone interested in an easy to use approach to modeling complex systems authored by perhaps the most original systems ecologists of the century will want this book. To further enhance the users ability to apply the lessons of this book, there is included a CD-ROM disc which provides the fundamental tools for modeling at all scales.Key Features* The book makes it possible to teach modeling and simulation without much prior knowledge of mathematics* Reasons for modeling and simulation are discussed* The book makes modeling and simulation fun by keeping focused on simplified overview minimodels that have important principles to science and society* The steps in successive chapters are arranged so that readers can teach themselves modeling, simulation, and the programming necessary to simulate the systems they diagram* The CD-ROM has minimodel programs and versions of QuickBasic and EXTEND to run them

Tissue Mechanics

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Author : Stephen C. Cowin
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-10-25

Tissue Mechanics written by Stephen C. Cowin and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-10-25 with Technology & Engineering categories.

The structures of living tissues are continually changing due to growth and response to the tissue environment, including the mechanical environment. Tissue Mechanics is an in-depth look at the mechanics of tissues. Tissue Mechanics describes the nature of the composite components of a tissue, the cellular processes that produce these constituents, the assembly of the constituents into a hierarchical structure, and the behavior of the tissue’s composite structure in the adaptation to its mechanical environment. Organized as a textbook for the student needing to acquire the core competencies, Tissue Mechanics will meet the demands of advanced undergraduate or graduate coursework in Biomedical Engineering, as well as, Chemical, Civil, and Mechanical Engineering. Key features: Detailed Illustrations Example problems, including problems at the end of sections A separate solutions manual available for course instructors A website (http://tissue-mechanics.com/) that has been established to provide supplemental material for the book, including downloadable additional chapters on specific tissues, downloadable PowerPoint presentations of all the book's chapters, and additional exercises and examples for the existing chapters. About the Authors: Stephen C. Cowin is a City University of New York Distinguished Professor, Departments of Biomedical and Mechanical Engineering, City College of the City University of New York and also an Adjunct Professor of Orthopaedics, at the Mt. Sinai School of Medicine in New York, New York. In 1985 he received the Society of Tulane Engineers and Lee H. Johnson Award for Teaching Excellence and a recipient of the European Society of Biomechanics Research Award in 1994. In 1999 he received the H. R. Lissner medal of the ASME for contributions to biomedical engineering. In 2004 he was elected to the National Academy of Engineering (NAE) and he also received the Maurice A. Biot medal of the American Society of Civil Engineers (ASCE). Stephen B. Doty is a Senior Scientist at Hospital for Special Surgery, New York, New York and Adjunct Professor, School of Dental and Oral Surgery, Columbia University, New York, NY. He has over 100 publications in the field of anatomy, developmental biology, and the physiology of skeletal and connective tissues. His honors include several commendations for participation in the Russian/NASA spaceflights, the Spacelab Life Science NASA spaceflights, and numerous Shuttle missions that studied the influence of spaceflight on skeletal physiology. He presently is on the scientific advisory board of the National Space Biomedical Research Institute, Houston, Texas.

Cellular And Biomolecular Mechanics And Mechanobiology

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Author : Amit Gefen
language : en
Publisher: Springer Science & Business Media
Release Date : 2010-12-02

Cellular And Biomolecular Mechanics And Mechanobiology written by Amit Gefen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2010-12-02 with Technology & Engineering categories.

This book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanical loads.

Mechanics Of Biological Tissue

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Author : Gerhard A. Holzapfel
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-06-03

Mechanics Of Biological Tissue written by Gerhard A. Holzapfel and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-06-03 with Science categories.

The mechanics of biological tissues is a multidisciplinary and rapidly expanding area of research. This book points to important directions combining mechanical sciences with the new developments in biology. It delivers articles on mechanics of tissues at the molecular, cellular, tissue and organ levels.

Nonlinear Theory Of Elasticity Applications In Biomechanics Revised Edition

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Author : Larry A Taber
language : en
Publisher: World Scientific
Release Date : 2023-03-10

Nonlinear Theory Of Elasticity Applications In Biomechanics Revised Edition written by Larry A Taber and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-10 with Technology & Engineering categories.

Soft biological tissues often undergo large (nearly) elastic deformations that can be modeled using the nonlinear theory of elasticity. Because of the varied approaches to nonlinear elasticity in the literature, some aspects of the subject may be difficult to appreciate.This volume clarifies and unifies those treatments, illustrating the advantages and disadvantages of each through various examples in biomechanics. Applications include muscle, arteries, the heart, and embryonic tissues.The revised edition includes new end-of-chapter problems, including answers and detailed solutions to most. The useful reference can be a good textbook for self-study, as well as senior- and graduate-level courses in biomechanics and nonlinear elasticity.

Advanced Continuum Theories And Finite Element Analyses

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Author : James D Lee
language : en
Publisher: World Scientific
Release Date : 2020-01-08

Advanced Continuum Theories And Finite Element Analyses written by James D Lee and has been published by World Scientific this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-01-08 with Technology & Engineering categories.

This comprehensive volume presents a unified framework of continuum theories. It indicates that (i) microcontinuum theories (micromorphic and micropolar theories) are natural extension of classical continuum mechanics, and (ii) classical continuum mechanics is a special case of microcontinuum theories when the deformable material point is idealized as a single mathematical point. The kinematics and basic laws are rigorously derived. Based on axiomatic approach, constitutive theory is systematically derived for various kinds of materials, ranging from Stokesian fluid to thermo-visco-elastic-plastic solid. Material force and Thermomechanical-electromagnetic coupling are introduced and discussed. Moreover, general finite element methods for large-strain thermomechanical coupling physical phenomena are systematically formulated. Also, non-classical continuum theories (Nonlocal Theory, Mechanobiology, 4D printing, Poromechanics, and Non-Self-Similar Crack Propagation) are rigorously formulated with applications and demonstrated numerically.As an advanced monograph, this unique compendium can also be used as a textbook for several graduate courses, including continuum mechanics, finite element methods, and advanced engineering science theories. Extensive problems are provided to help students to better understand the topics covered.

Introduction To Cell Mechanics And Mechanobiology

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Author : Christopher R. Jacobs
language : en
Publisher: Garland Science
Release Date : 2012-11-16

Introduction To Cell Mechanics And Mechanobiology written by Christopher R. Jacobs and has been published by Garland Science this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-11-16 with Medical categories.

Introduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical prope