Control Of Cell Fate In The Circulatory And Ventilatory Systems


Control Of Cell Fate In The Circulatory And Ventilatory Systems
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Control Of Cell Fate In The Circulatory And Ventilatory Systems


Control Of Cell Fate In The Circulatory And Ventilatory Systems
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Author :
language : en
Publisher:
Release Date : 2011-11-01

Control Of Cell Fate In The Circulatory And Ventilatory Systems written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-01 with categories.




Control Of Cell Fate In The Circulatory And Ventilatory Systems


Control Of Cell Fate In The Circulatory And Ventilatory Systems
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Author : Marc Thiriet
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-11-01

Control Of Cell Fate In The Circulatory And Ventilatory Systems written by Marc Thiriet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-11-01 with Science categories.


The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to environmental conditions. Volume 2 begins with a survey of the cell types of the nervous and endocrine systems involved in the regulation of the vasculature and respiratory tract and growth factors. It then describes major cell events in the circulatory and ventilatory systems, such as cell growth, proliferation, migration, and death. Circadian cycles that drive rhythmic gene transcription are also covered.



Cell And Tissue Organization In The Circulatory And Ventilatory Systems


Cell And Tissue Organization In The Circulatory And Ventilatory Systems
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Author : Marc Thiriet
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-08

Cell And Tissue Organization In The Circulatory And Ventilatory Systems written by Marc Thiriet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-08 with Science categories.


The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. The present volume is devoted to cellular events that allow adaptation to environmental conditions, particularly mechanotransduction. It begins with cell organization and a survey of cell types in the vasculature and respiratory tract. It then addresses cell structure and functions, especially in interactions with adjoining cells and matrix.



Intracellular Signaling Mediators In The Circulatory And Ventilatory Systems


Intracellular Signaling Mediators In The Circulatory And Ventilatory Systems
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Author : Marc Thiriet
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-09-26

Intracellular Signaling Mediators In The Circulatory And Ventilatory Systems written by Marc Thiriet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-09-26 with Science categories.


The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to phenomenological models of nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 4 is devoted to major sets of intracellular mediators that transmit signals upon stimulation of cell-surface receptors. Activation of signaling effectors triggers the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Complex stages of cell signaling can be studied using proper mathematical models, once the role of each component is carefully handled. Volume 4 also reviews various categories of cytosolic and/or nuclear mediators and illustrates some major signal transduction pathways, such as NFkappaB axis, oxygen sensing, and mechanotransduction.



Handbook Of Fluid Dynamics


Handbook Of Fluid Dynamics
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Author : Richard W. Johnson
language : en
Publisher: CRC Press
Release Date : 2016-04-06

Handbook Of Fluid Dynamics written by Richard W. Johnson and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-04-06 with Science categories.


Handbook of Fluid Dynamics offers balanced coverage of the three traditional areas of fluid dynamics—theoretical, computational, and experimental—complete with valuable appendices presenting the mathematics of fluid dynamics, tables of dimensionless numbers, and tables of the properties of gases and vapors. Each chapter introduces a different fluid dynamics topic, discusses the pertinent issues, outlines proven techniques for addressing those issues, and supplies useful references for further research. Covering all major aspects of classical and modern fluid dynamics, this fully updated Second Edition: Reflects the latest fluid dynamics research and engineering applications Includes new sections on emerging fields, most notably micro- and nanofluidics Surveys the range of numerical and computational methods used in fluid dynamics analysis and design Expands the scope of a number of contemporary topics by incorporating new experimental methods, more numerical approaches, and additional areas for the application of fluid dynamics Handbook of Fluid Dynamics, Second Edition provides an indispensable resource for professionals entering the field of fluid dynamics. The book also enables experts specialized in areas outside fluid dynamics to become familiar with the field.



Signaling At The Cell Surface In The Circulatory And Ventilatory Systems


Signaling At The Cell Surface In The Circulatory And Ventilatory Systems
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Author : Marc Thiriet
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-14

Signaling At The Cell Surface In The Circulatory And Ventilatory Systems written by Marc Thiriet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-14 with Science categories.


The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms when the vessel lumen caliber varies markedly. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volume 3 is devoted to the set of mediators of the cell surface, especially ion and molecular carriers and catalytic receptors that, once liganded and activated, initiate signal transduction pathways. Intracellular cascades of chemical reactions trigger the release of substances stored in cellular organelles and/or gene transcription and protein synthesis. Primary mediators are included in models of regulated cellular processes, but multiple secondary signaling components are discarded to allow simple, representative modeling and to manage their inverse problems.



Mathematical Modeling And Optimization Of Complex Structures


Mathematical Modeling And Optimization Of Complex Structures
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Author : Pekka Neittaanmäki
language : en
Publisher: Springer
Release Date : 2015-10-07

Mathematical Modeling And Optimization Of Complex Structures written by Pekka Neittaanmäki and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2015-10-07 with Technology & Engineering categories.


This volume contains selected papers in three closely related areas: mathematical modeling in mechanics, numerical analysis, and optimization methods. The papers are based upon talks presented on the International Conference for Mathematical Modeling and Optimization in Mechanics, held in Jyväskylä, Finland, March 6-7, 2014 dedicated to Prof. N. Banichuk on the occasion of his 70th birthday. The articles are written by well-known scientists working in computational mechanics and in optimization of complicated technical models. Also, the volume contains papers discussing the historical development, the state of the art, new ideas, and open problems arising in modern continuum mechanics and applied optimization problems. Several papers are concerned with mathematical problems in numerical analysis, which are also closely related to important mechanical models. The main topics treated include: * Computer simulation methods in mechanics, physics, and biology; * Variational problems and methods; minimization algorithms; * Optimal control problems with distributed and discrete control; * Shape optimization and shape design problems in science and engineering; * Sensitivity analysis and parameters optimization of complex systems.



Tissue Functioning And Remodeling In The Circulatory And Ventilatory Systems


Tissue Functioning And Remodeling In The Circulatory And Ventilatory Systems
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Author : Marc Thiriet
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-01-11

Tissue Functioning And Remodeling In The Circulatory And Ventilatory Systems written by Marc Thiriet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-01-11 with Science categories.


The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. Volume 5 is devoted to cells, tissues, and organs of the cardiovascular and ventilatory systems with an emphasis on mechanotransduction-based regulation of flow. The blood vessel wall is a living tissue that quickly reacts to loads applied on it by the flowing blood. In any segment of a blood vessel, the endothelial and smooth muscle cells can sense unusual time variations in small-magnitude wall shear stress and large-amplitude wall stretch generated by abnormal hemodynamic stresses. These cells respond with a short-time scale (from seconds to hours) to adapt the vessel caliber. Since such adaptive cell activities can be described using mathematical models, a key objective of this volume is to identify the mesoscopic agents and nanoscopic mediators required to derive adequate mathematical models. The resulting biomathematical models and corresponding simulation software can be incorporated into platforms developed in virtual physiology for improved understanding and training.



Numerical Simulations Of Coupled Problems In Engineering


Numerical Simulations Of Coupled Problems In Engineering
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Author : Sergio R. Idelsohn
language : en
Publisher: Springer
Release Date : 2014-05-09

Numerical Simulations Of Coupled Problems In Engineering written by Sergio R. Idelsohn and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2014-05-09 with Technology & Engineering categories.


This book presents and discusses mathematical models, numerical methods and computational techniques used for solving coupled problems in science and engineering. It takes a step forward in the formulation and solution of real-life problems with a multidisciplinary vision, accounting for all of the complex couplings involved in the physical description. Simulation of multifaceted physics problems is a common task in applied research and industry. Often a suitable solver is built by connecting together several single-aspect solvers into a network. In this book, research in various fields was selected for consideration: adaptive methodology for multi-physics solvers, multi-physics phenomena and coupled-field solutions, leading to computationally intensive structural analysis. The strategies which are used to keep these problems computationally affordable are of special interest, and make this an essential book.



Anatomy And Physiology Of The Circulatory And Ventilatory Systems


Anatomy And Physiology Of The Circulatory And Ventilatory Systems
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Author : Marc Thiriet
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-11-27

Anatomy And Physiology Of The Circulatory And Ventilatory Systems written by Marc Thiriet and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-11-27 with Science categories.


Together, the volumes in this series present all of the data needed at various length scales for a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to, and remove carbon dioxide from, the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanism. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems, together with the mathematical tools to describe their functioning in quantitative terms. The present volume focuses on macroscopic aspects of the cardiovascular and respiratory systems in normal conditions, i.e., anatomy and physiology, as well as the acquisition and processing of medical images and physiological signals.