Controlled Release In Oral Drug Delivery
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Controlled Release In Oral Drug Delivery
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Author : Clive G. Wilson
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-09-22
Controlled Release In Oral Drug Delivery written by Clive G. Wilson and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-22 with Medical categories.
Controlled Release in Oral Drug Delivery provides focus on specific topics, complementing other books in the initial CRS series. Each chapter sets the context for the inventions described and describe the latitude that the inventions allow. In order to provide some similar look to each chapter, the coverage includes the historical overview, candidate drugs, factors influencing design and development, formulation and manufacturing and delivery system design. This volume was written along three main sections: the relevant anatomy and physiology, a discussion on candidates for oral drug delivery and the major three groups of controlled release systems: diffusion control (swelling and inert matrices); environmental control (pH sensitive coatings, time control, enzymatic control, pressure control) and finally lipidic systems.
Controlled Release In Oral Drug Delivery
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Author :
language : en
Publisher: Springer
Release Date : 2011-09-25
Controlled Release In Oral Drug Delivery written by and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-09-25 with categories.
Oral Controlled Release Formulation Design And Drug Delivery
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Author : Hong Wen
language : en
Publisher: John Wiley & Sons
Release Date : 2011-01-14
Oral Controlled Release Formulation Design And Drug Delivery written by Hong Wen and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-01-14 with Science categories.
This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.
Oral Drug Delivery For Modified Release Formulations
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Author : Edmund S. Kostewicz
language : en
Publisher: John Wiley & Sons
Release Date : 2022-04-26
Oral Drug Delivery For Modified Release Formulations written by Edmund S. Kostewicz and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-04-26 with Medical categories.
ORAL DRUG DELIVERY FOR MODIFIED RELEASE FORMULATIONS Provides pharmaceutical development scientists with a detailed reference guide for the development of MR formulations Oral Drug Delivery for Modified Release Formulations is an up-to-date review of the key aspects of oral absorption from modified-release (MR) dosage forms. This edited volume provides in-depth coverage of the physiological factors that influence drug release and of the design and evaluation of MR formulations. Divided into three sections, the book begins by describing the gastrointestinal tract (GIT) and detailing the conditions and absorption processes occurring in the GIT that determine a formulation’s oral bioavailability. The second section explores the design of modified release formulations, covering early drug substance testing, the biopharmaceutics classification system, an array of formulation technologies that can be used for MR dosage forms, and more. The final section focuses on in vitro, in silico, and in vivo evaluation and regulatory considerations for MR formulations. Topics include biorelevant dissolution testing, preclinical evaluation, and physiologically-based pharmacokinetic modelling (PBPK) of in vivo behaviour. Featuring contributions from leading researchers with expertise in the different aspects of MR formulations, this volume: Provides authoritative coverage of physiology, physicochemical determinants, and in-vitro in-vivo correlation (IVIVC) Explains the different types of MR formulations and defines the key terms used in the field Discusses the present status of MR technologies and identifies current gaps in research Includes a summary of regulatory guidelines from both the US and the EU Shares industrial experiences and perspectives on the evaluation of MR dosage formulations Oral Drug Delivery for Modified Release Formulations is an invaluable reference and guide for researchers, industrial scientists, and graduate students in general areas of drug delivery including pharmaceutics, pharmaceutical sciences, biomedical engineering, polymer and materials science, and chemical and biochemical engineering.
Fundamentals And Applications Of Controlled Release Drug Delivery
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Author : Juergen Siepmann
language : en
Publisher: Springer Science & Business Media
Release Date : 2011-12-15
Fundamentals And Applications Of Controlled Release Drug Delivery written by Juergen Siepmann and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-15 with Medical categories.
This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.
Controlled Drug Release Of Oral Dosage Forms
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Author : Jean-Maurice Vergnaud
language : en
Publisher: CRC Press
Release Date : 1993-07-31
Controlled Drug Release Of Oral Dosage Forms written by Jean-Maurice Vergnaud and has been published by CRC Press this book supported file pdf, txt, epub, kindle and other format this book has been release on 1993-07-31 with Medical categories.
Numerical analysis of matter transfer is an area that pharmacists find difficult, but which is a technique frequently used in preparing controlled drug release and oral dosage forms. A practical guide which explains how to carry out the numerical analysis of matter transfer - a vital process when examining the formulation of oral dosage forms with controlled drug release. The author models the process of drug delivery using numerical analysis and computerization.
Update On Polymers For Oral Drug Delivery
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Author : Fang Liu
language : en
Publisher: Smithers Rapra
Release Date : 2011-12-31
Update On Polymers For Oral Drug Delivery written by Fang Liu and has been published by Smithers Rapra this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011-12-31 with Medical categories.
The preferred route for drug delivery remains the oral route, but oral drug delivery has now developed beyond traditional dosage forms such as tablets and capsules. Nowadays it is possible to use polymers to allow drugs to be targeted to specific sites in the gastrointestinal tract, and to extend the drug release profile. In addition, polymers can be engineered to allow oral delivery of such complex molecules as proteins, peptides, and even genes. This book gives a comprehensive summary of oral drug delivery systems, both conventional and novel, and the ways in which polymers have been adapted for these systems. Particular attention is devoted to gastrointestinal physiology and the physio-chemical properties of polymers in order to understand the factors affecting their performance in practice. This update will interest everyone involved in the pharmaceutical world, whether in academia or in industry. It will be of particular value to those responsible for designing new oral drug delivery systems involving polymers. It will provide a useful reference text both for researchers and manufacturers, and will also be a helpful introduction for students of all levels to the application of polymers in pharmacy.
Phase Modification Of Non Aqueous Emulsions For Controlled Release Oral Drug Delivery
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Author : Sarah Mary Connolly
language : en
Publisher:
Release Date : 2008
Phase Modification Of Non Aqueous Emulsions For Controlled Release Oral Drug Delivery written by Sarah Mary Connolly and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008 with categories.
Chemical Engineering In The Pharmaceutical Industry
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Author : Mary T. am Ende
language : en
Publisher: John Wiley & Sons
Release Date : 2019-04-08
Chemical Engineering In The Pharmaceutical Industry written by Mary T. am Ende and has been published by John Wiley & Sons this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-04-08 with Technology & Engineering categories.
A guide to the important chemical engineering concepts for the development of new drugs, revised second edition The revised and updated second edition of Chemical Engineering in the Pharmaceutical Industry offers a guide to the experimental and computational methods related to drug product design and development. The second edition has been greatly expanded and covers a range of topics related to formulation design and process development of drug products. The authors review basic analytics for quantitation of drug product quality attributes, such as potency, purity, content uniformity, and dissolution, that are addressed with consideration of the applied statistics, process analytical technology, and process control. The 2nd Edition is divided into two separate books: 1) Active Pharmaceutical Ingredients (API’s) and 2) Drug Product Design, Development and Modeling. The contributors explore technology transfer and scale-up of batch processes that are exemplified experimentally and computationally. Written for engineers working in the field, the book examines in-silico process modeling tools that streamline experimental screening approaches. In addition, the authors discuss the emerging field of continuous drug product manufacturing. This revised second edition: Contains 21 new or revised chapters, including chapters on quality by design, computational approaches for drug product modeling, process design with PAT and process control, engineering challenges and solutions Covers chemistry and engineering activities related to dosage form design, and process development, and scale-up Offers analytical methods and applied statistics that highlight drug product quality attributes as design features Presents updated and new example calculations and associated solutions Includes contributions from leading experts in the field Written for pharmaceutical engineers, chemical engineers, undergraduate and graduation students, and professionals in the field of pharmaceutical sciences and manufacturing, Chemical Engineering in the Pharmaceutical Industry, Second Edition contains information designed to be of use from the engineer's perspective and spans information from solid to semi-solid to lyophilized drug products.
Design Of Controlled Release Drug Delivery Systems
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Author : Xiaoling Li
language : en
Publisher: McGraw Hill Professional
Release Date : 2005-11-24
Design Of Controlled Release Drug Delivery Systems written by Xiaoling Li and has been published by McGraw Hill Professional this book supported file pdf, txt, epub, kindle and other format this book has been release on 2005-11-24 with Technology & Engineering categories.
The goal of every drug delivery system is to deliver the precise amount of a drug at a pre-programmed rate to the desired location in order to achieve the drug level necessary for the treatment. An essential guide for biomedical engineers and pharmaceutical designers, this resource combines physicochemical principles with physiological processes to facilitate the design of systems that will deliver medication at the time and place it is most needed.