Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study


Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study
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Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study


Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study
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Author : Olgun Elicin
language : en
Publisher: Frontiers Media SA
Release Date : 2020-02-26

Controversial Issues In The Management Of Head And Neck Cancer A Swiss Multidisciplinary And Multi Institutional Patterns Of Care Study written by Olgun Elicin and has been published by Frontiers Media SA this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-02-26 with categories.


The heterogeneity in the practice of diagnosis and treatment of head and neck squamous cell carcinoma (HNSCC) is known and expected to be inversely correlated with the level of evidence on a given topic. Literature on various aspects of management of HNSCC were previously published, but were usually restricted within narrow foci. Due to the lack of a similar comprehensive work published so far, the Head and Neck Cancer Working Group of Swiss Group for Clinical Cancer Research (SAKK) decided to perform a survey covering the whole spectrum of controversial topics concerning the diagnosis and the treatment of HNSCC among its member institutions. This survey was designed to discuss current diagnostic and treatment strategies for HNSCC of all localizations, and to find out probable differences and level of consensus between the participating academic institutions by means of a questionnaire-based pattern of care study. The items in the survey was generated with a scored voting system by inclusion of all involved centers, and divided into four sections, each of them not exceeding twenty questions: head and neck surgery, radiation oncology, medical oncology and biomarkers. Surely, the topics and questions were intentionally chosen from controversial areas. Nonetheless, the lack of major consensus in most queried areas provide an insight to head and neck oncologist in terms of the scope of heterogeneity in their practice. Although none of the participated centers being plainly wrong, it is still disturbing to see, that a patient may be treated with quite discrepant diagnostic and treatment concepts even in a relatively small country adhering to up to date evidence based medicine. We believe that this work will serve the head and neck oncologists to be aware of their discrepancies and to stimulate discussion toward standardization of practice and prioritize topics of future clinical research.



Surgical Management Of Head And Neck Pathologies


Surgical Management Of Head And Neck Pathologies
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Author : Ho-Hyun (Brian) Sun
language : en
Publisher: BoD – Books on Demand
Release Date : 2021-10-13

Surgical Management Of Head And Neck Pathologies written by Ho-Hyun (Brian) Sun and has been published by BoD – Books on Demand this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-10-13 with Medical categories.


The book is an introduction to concepts in head and neck surgical pathology that are both novel and proven. Chapters discuss the various anatomic, reconstructive, and esthetic considerations that are often unique to surgeries of the head, face, and neck. International cooperation was made to ensure that a wide range of perspectives is presented in this volume.



Head And Neck Cancer


Head And Neck Cancer
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Author : N. J. Roland
language : en
Publisher:
Release Date : 2011

Head And Neck Cancer written by N. J. Roland and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2011 with Head categories.




Carcinoma Of The Larynx And Hypopharynx


Carcinoma Of The Larynx And Hypopharynx
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Author : Sudhir Bahadur
language : en
Publisher: Springer
Release Date : 2019-02-20

Carcinoma Of The Larynx And Hypopharynx written by Sudhir Bahadur and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-02-20 with Medical categories.


Carcinomas of the larynx and hypopharynx present unique challenges when it comes to their assessment and management. Management involves the essential dilemma of optimizing cure rates while also ensuring that potential disability due to compromised airway, voice and swallowing is minimized. Treatment decisions involve careful disease assessment, judicious multispecialty decision-making, and subsequent meticulous implementation of the selected treatment modalities. The critical nature of each of these steps has led to dramatic advances in assessment techniques (radiology, endoscopy and photography, stroboscopy, narrow band imaging, contact endoscopy) and also in treatment methods (radiation therapy, combined concurrent chemo-radiation, combined sequential chemo-radiation, trans-oral CO2 laser and robotic surgery, partial laryngectomy, total laryngectomy, extended total laryngectomy). As such, treatment decisions have become increasingly complex with the twin objectives of maximizing cure as well as function preservation and are based on tumor stage, tumor location, systemic co-morbidities, nutritional status, patient priorities, and social and economic factors. This multidisciplinary book has been written by a team of editors with considerable experience and expertise in these critical areas and a deep understanding of teamwork and the strengths and limitations of individual technologies and treatments. It presents a homogeneous and unbiased view that is applicable to all specialties involved in the care of larynx and hypopharynx cancers.



Betel Quid And Areca Nut Chewing And Some Areca Nut Derived Nitrosamines


Betel Quid And Areca Nut Chewing And Some Areca Nut Derived Nitrosamines
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Author : IARC Working Group on the Evaluation of Carcinogenic Risks to Humans
language : en
Publisher: IARC
Release Date : 2004

Betel Quid And Areca Nut Chewing And Some Areca Nut Derived Nitrosamines written by IARC Working Group on the Evaluation of Carcinogenic Risks to Humans and has been published by IARC this book supported file pdf, txt, epub, kindle and other format this book has been release on 2004 with Health & Fitness categories.


A working group of sixteen experts from seven countries re-evaluated the evidence of the carcinogenicity of betel-quid and areca-nut chewing and some areca-nut related nitrosamines. Betel-quid and areca-nut chewing are widely practised in many parts of Asia and in Asian-migrant communities elsewhere in the world. There are hundreds of millions of users worldwide. They evaluated betel quid with tobacco as carcinogenic to humans (Group 1) on the basis of sufficient evidence of an increased risk of cancer of the oral cavity, pharynx and oesophagus. The working group reviewed epidemiological studies of human cancer, mainly studies from India, Pakistan and Taiwan (China). Studies on betel quid with tobacco and areca nut with tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. The working group also evaluated betel quid without tobacco as carcinogenic to humans (Group 1), on the basis of sufficient evidence of an increased risk of oral cancer. Studies on betel quid without tobacco and areca nut without tobacco in experimental animals now also provide sufficient evidence of carcinogenicity. Areca nut, a common ingredient of betel quid and many different chewing preparations, including those available commercially, has been observed to cause oral submucous fibrosis



Metastases In Head And Neck Cancer


Metastases In Head And Neck Cancer
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Author : Jochen A. Werner
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Metastases In Head And Neck Cancer written by Jochen A. Werner and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


-Richly illustrated; 109 illustrations, 57 in color -Cover a wide range of diagnostic and theraputic techniques, i.e. MRI, PET, surgical treatment, radiation therapy



Anterior Skull Base Tumors


Anterior Skull Base Tumors
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Author : P. Nicolai
language : en
Publisher: Karger Medical and Scientific Publishers
Release Date : 2020-07-30

Anterior Skull Base Tumors written by P. Nicolai and has been published by Karger Medical and Scientific Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-30 with Medical categories.


In recent years, interest in the management of anterior skull base tumors has been fostered by the introduction and subsequent rapid expansion of indications of transnasal endoscopic techniques. In parallel, extraordinary progress has been made in all the other disciplines which are involved in the complex process of managing anterior skull base tumors, leading to substantial improvements in diagnosis and treatment. The anterior skull base can be involved in a large variety of tumors of a varying nature and histology, which in the majority of cases originate from adjacent anatomic sites. In fact, primary lesions of the anterior skull base mainly include osteoma and other tumors originating from bone and cartilage. Tumors involving the anterior skull base have their origin prevalently in the sinonasal tract, but lesions developing on the intracranial site, such as meningiomas, may also extend caudally to encroach upon this area. All these lesions are rare, which means that the pertinent literature does not include prospective studies or treatment guidelines based on a high level of evidence. In view of the extreme histological variability of lesions involving the anterior skull base, much emphasis has been placed on addressing the different nuances of treatment in relation to histology, especially for malignant tumors. The chapters focusing on surgery provide divergent views on selection criteria for a specific surgical technique, which is the aim of this publication.



Carbon Ion Radiotherapy


Carbon Ion Radiotherapy
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Author : Hirohiko Tsujii
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-12-25

Carbon Ion Radiotherapy written by Hirohiko Tsujii and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-12-25 with Medical categories.


This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.



Critical Issues In Head And Neck Oncology


Critical Issues In Head And Neck Oncology
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Author : Jan B. Vermorken
language : en
Publisher: Springer Nature
Release Date : 2023-03-27

Critical Issues In Head And Neck Oncology written by Jan B. Vermorken and has been published by Springer Nature this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-27 with Medical categories.


This is an open access book. With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provides significant detail on a wide range of topics including: the role of new targets for treatment, immunotherapy, resistance mechanisms, standardizing molecular profiling programs, and new methods to guide therapeutic approaches. In addition different disease situations are addressed including different treatment approaches in primary disease and in recurrent and/or metastatic disease as well as new developments in pathology, surgery and reconstruction techniques, new systemic therapies in salivary gland cancer, and supportive care and follow-up. All disciplines involved in the treatment of head & neck cancer are covered with a focus on translation into daily practice. The 8th-THNO is designed for medical oncologists, head and neck surgeons, radiation oncologists, otolaryngologists, and other medical professionals involved in the treatment of patients with head and neck cancer.



Bulletin Of The Atomic Scientists


Bulletin Of The Atomic Scientists
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Author :
language : en
Publisher:
Release Date : 1972-10

Bulletin Of The Atomic Scientists written by and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 1972-10 with categories.


The Bulletin of the Atomic Scientists is the premier public resource on scientific and technological developments that impact global security. Founded by Manhattan Project Scientists, the Bulletin's iconic "Doomsday Clock" stimulates solutions for a safer world.