Coronaviruses


Coronaviruses
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Coronaviruses Volume 2


Coronaviruses Volume 2
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Author : Jean-Marc Sabatier
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-12-22

Coronaviruses Volume 2 written by Jean-Marc Sabatier and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-12-22 with Medical categories.


Scientific literature on SARS-COV-2 viruses and its variants (especially variants of concern such as the ‘Delta variant’) and important cellular targets is crucial to help researchers, virologists and clinicians around the globe to develop a new generation of safer and more effective vaccines, and other treatments to address COVID-19 disease. The accompanying damage to the many organs and tissues of SARS-Co-2-infected people also needs to be understood and researchers are using data to devise meaningful protocols for treating these symptoms. This second volume of Coronaviruses brings together more useful information about the prevention/vaccination, and chemotherapies for the potential treatment of coronavirus infections. The volume includes eight chapters: (1) Broad spectrum antivirals to combat COVID-19 The reality and challenges, (2) COVID-19: Preventive and protective control management strategies, (3) Plant-derived extracts and bioactive compounds against coronavirus progression: preventive effects, mechanistic aspects, and structures, (4) Gastroenteritis: symptoms and epidemiology of SARS-CoV-2, (5) The chronicles of coronavirus: A Chinese king who conquered the entire world, (6) Traditional medicine as a natural remedy in ARDS & COVID-19, (7) Molecular pathogenesis of human coronaviruses of the 21st century, (8) COVID-19, mental health and neuropathophysiology of pain related to temporomandibular disorder. The volume serves as a novel compilation of key data on SARS-CoV-2 and COVID-19 and represents a resource of the utmost value for all scholars studying SARS-CoV infections. It should also be of great interest to clinicians who may be facing an overwhelming number of individuals affected with COVID-19, with over 267 million global cases documented as of the first week of December 2021).



Coronaviruses With Special Emphasis On First Insights Concerning Sars


Coronaviruses With Special Emphasis On First Insights Concerning Sars
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Author : Axel Schmidt
language : en
Publisher: Springer Science & Business Media
Release Date : 2006-03-30

Coronaviruses With Special Emphasis On First Insights Concerning Sars written by Axel Schmidt and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2006-03-30 with Medical categories.


-SARS has received much attention and coverage by the media and has a high impact on the public making this a hot research topic for scientists. -



Pathogenic Coronaviruses Of Humans And Animals


Pathogenic Coronaviruses Of Humans And Animals
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Author : Lisa A. Beltz
language : en
Publisher: Elsevier
Release Date : 2022-10-13

Pathogenic Coronaviruses Of Humans And Animals written by Lisa A. Beltz and has been published by Elsevier this book supported file pdf, txt, epub, kindle and other format this book has been release on 2022-10-13 with Science categories.


Pathogenic Coronaviruses of Humans and Animals: SARS, MERS, COVID-19, and Animal Coronaviruses with Zoonotic Potential provides relevant information about common human coronaviruses that may mutate to increase their virulence. The addition of animal coronaviruses allows awareness of not only the potential of zoonotic transmission of coronaviruses from wild animals such as bats and rodents, but also from domestic agricultural and companion animals. The book opens with an introductory chapter on viruses, the immune system, coronaviruses, and their classifications, prevention and protection. Sections also cover history, disease, causative virus, immune response, diagnosis, treatment, prevention and surveillance. The book's remaining chapters discuss coronaviruses with possible zoonotic transmission of domestic, semi-domestic animals and companion animals. It concludes with future perspectives of coronavirus mutations, modeling, protective measures and a discussion around pandemics and infectious diseases from around the globe. Covers SARS-CoV, MERS-CoV and SARS-CoV-2 as well as coronaviruses with possible zoonotic transmission of domestic, semi-domestic animals and companion animals Complements previous studies by bringing together information that compares human and animal coronaviruses Includes a glossary and coronavirus disease overviews of humans and animals



100 Questions Answers About Coronaviruses


100 Questions Answers About Coronaviruses
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Author : Delthia Ricks
language : en
Publisher: Jones & Bartlett Learning
Release Date : 2021-03-02

100 Questions Answers About Coronaviruses written by Delthia Ricks and has been published by Jones & Bartlett Learning this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-03-02 with Medical categories.


100 Questions & Answers About Coronaviruses is a timely resource that organizes and distills cutting-edge information and data on COVID-19 in a single, convenient, easy-to-read resource. Featuring a foreword by Dr. Aaron Glatt, Chairman and Chief of Infectious Diseases and Hospital Epidemiologist at Mount Sinai South Nassau, 100 Questions and Answers About Coronaviruses begins with a history and myths about coronaviruses and progresses to answer questions about how COVID-19 affects children and adults, current vaccine research, quarantine, social distancing, preventing future pandemics, and more often asked questions. 100 Questions & Answers About Coronaviruses is an invaluable resource for every nursing or public health student and a must-read for anyone interested in learning about the virus that is reshaping our daily lives.



Coronaviruses And Their Diseases


Coronaviruses And Their Diseases
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Author : David Cavanagh
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-03-09

Coronaviruses And Their Diseases written by David Cavanagh and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-03-09 with Medical categories.


Interest in the coronaviruses has never been greater. Their economic impact is considerable as they infect humans, livestock, poultry and companion animals. Murine hepatitis virus (MHV) infection of the mouse and rat central nervous systems are the subject of intense study; these investigations are providing insights into the potential role of viruses in human neurological diseases and, more generally, into mechanisms causing neurological damage. The single-stranded, positive-sense RNA genomes of two species of these enveloped viruses (IBV and MHV) have been cloned completely and one of them (lBV) sequenced in its entirety, revealing a genome size of some 27000 nucleotides. This has made possible more incisive investigations into the nature of those polypeptides, encoded by more than half of the genome, which are likely to contribute, in the main, to RNA polymerase/replicase activity. Intriguingly, ribosomal frameshifting is exhibited within the mRNA coding for these polypeptides. The cloning/sequencing phase of coronavirology for which the 1980's will be partly remembered, has provided a sound framework for furthex: studies of the virus structural proteins and also some provocative insights relevant to these studies. The large spike glycoprotein(s), responsible for membrane fusion and bearing important antigenic sites, varies amazingly in length and composition both within as well as between coronavirus species. Receptors on host cells have been identified. The integral membrane glycoprotein (M) has been shown to use internal hydrophobic sequences to direct translocation within membranes.



Coronaviruses Volume 1


Coronaviruses Volume 1
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Author : Jean-Marc Sabatier
language : en
Publisher: Bentham Science Publishers
Release Date : 2021-05-24

Coronaviruses Volume 1 written by Jean-Marc Sabatier and has been published by Bentham Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2021-05-24 with Medical categories.


In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential and vital. Reports as of 20th April 2021 indicate over 141 million cases of SARS-CoV-2 infection worldwide (with over 3 million deaths recorded). This volume brings together essential data regarding prevention (vaccination), detection, and various approaches (chemotherapeutic drugs and antibodies) to the potential treatment of coronavirus infections. It presents six chapters concerning the following topics: (1) the resistance to the spread of SARS-CoV-2 and related Covid-19 diseases within a population based on the pre-existing immunity of a high proportion of individuals as a result infection or previous vaccination (2) the impact of the Covid-19 pandemic for the South Asian Association for Regional Cooperation (SAARC) region, comprising the Bangladesh, Bhutan, Maldives, Nepal, Pakistan, Sri Lanka, India, and Afghanistan (3) the effect of candidate drugs chloroquine and hydroxychloroquine on QT interval in infected patients with Covid-19 diseases (4) the antiviral potential of herbal-based immunomodulators (5) the humoral immune response in humans based on anti-SARS-CoV-2 antibodies to treat Covid-19 diseases (6) the various methods and strategies for diagnosing SARS-CoV-2 (and its variants) infection in hosts/humans. This compilation should prove to be a tool of crucial importance for researchers around the world working on research revolving around coronaviruses, as well as for clinicians confronted by a growing number of patients with COVID-19. [Series Introduction] Coronaviruses presents compilations of reviews which present information about coronaviridae. Volumes in the series present interesting data on the virology, molecular biology, pathogenesis and epidemiology of these viruses. Current topics such as SARS-CoV-2 infection, COVID-19 epidemiology, economic impact of COVID-19, and new coronavirus variants are also included. The series should prove to be an essential resource on this group of viruses for multidisciplinary researchers and healthcare professionals alike.



Biochemistry And Biology Of Coronaviruses


Biochemistry And Biology Of Coronaviruses
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Author : V. Ter Meulen
language : en
Publisher: Springer Science & Business Media
Release Date : 2013-06-29

Biochemistry And Biology Of Coronaviruses written by V. Ter Meulen and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2013-06-29 with Medical categories.


This book is the result of an international symposium held at the Institute of Virology and Immunobiology of the-University of WUrzburg, Germany, in October 1980. The intent of this symposium was to provide an opportunity to compare the data on coronavirus structure and replica tion as well as to discuss mechanisms of pathogenesis. For over a decade coronaviruses have been recognized as an important group of viruses which are responsible for a variety of diseases of clinical importance in animals and man. Recently new and interesting data on the molecular biology and pathogenesis of coronaviruses have become available and this led us to organize this meeting. The uniformity and diversity in this virus group was evaluated from a molecular point of view and the replication of coronaviruses appears to involve aspects which may be unique for this virus group. Additionally, in contrast to other positive strand RNA viruses it became clear that coronaviruses readily establish persistent infections in the host, a phenomenon which may lead to the different subacute or chronic disorders manifested during coronavirus infection. This volume presents a series of articles based upon the scientific presentation given at the symposium. In addition, there are two articles by B. W. J. Mahy and D. A. J. Tyrrell which summarize the current state of art concerning the biochemistry and biology of coronaviruses, respective ly. We believe this book will be of interest to all virologists and particularly to both established workers and newcomers to this field. V.



Coronaviruses


Coronaviruses
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Author : Hubert Laude
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Coronaviruses written by Hubert Laude and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Coronaviruses represent a major group of viruses of both molecular biological interest and clinical significance in animals and humans. During the past two decades, coronavirus research has been an expanding field and, since 1980, an international symposium was held every 3 years. We organized the yth symposium for providing an opportunity to assess important progresses made since the last symposium in Cambridge (U. K. ) and to suggest areas for future investigations. The symposium, held in September 1992, in Chantilly, France, was attended by 120 participants representing the majOlity of the laboratories engaged in the field. The present volume collects 75 papers which were presented during the yth symposium, thus providing a comprehensive view of the state of the art ofCoronavirology. The book is divided into 7 chapters. The first chapters gather reports dealing with genome organization, gene expression and structure-function relationships of the viral polypeptides. New sequence data about as yet poorly studied coronaviruses - canine coronavirus CCY and porcine epidemic diarrhoea virus PEDY - are presented. Increasing efforts appear to be devoted to the characterization of products of unknown function, encoded by various open reading frames present in the coronavirus genomes or delived from the processing of the large polymerase polyprotein. Due to the extreme size of their genome, the genetic engineering ofcoronavi\'uses through the production of full length cDNA clones is presently viewed as an unachievahle task.



Coronaviruses


Coronaviruses
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Author : M. Lai
language : en
Publisher: Springer Science & Business Media
Release Date : 2012-12-06

Coronaviruses written by M. Lai and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-12-06 with Medical categories.


Coronaviruses have emerged during the past ten years from being a group of viruses causing a variety of minor veterinary and human diseases to a major virus group of both clinical significance and molecular biological interest. Against this background, two international coronavirus symposia were held in 1980 and 1983. In recent years, the pace of coronavirus research has been quickened even more by infusion of recombinant DNA technology and establishment of various animal model systems to study the pathogenesis and immunology of coronavirus infections. We therefore organized the Third International Coronavirus Symposium held at Asilomar, California in September 1986, which was attended by more than 120 participants representing a cross section of both academia and industry. This symposium provided an exciting and stimulating forum for assessing the progress made since the last triennial symposium in Netherlands and to suggest the directions for future efforts. This volume collects the scientific papers presented in this symposium. Three loosely defined areas, Molecular biology, Virus-Cell Interaction and Viral Pathogenesis, are separated. These papers very nicely summarize the current status of coronavirus research. They contain a large amount of sequence data, including the complete sequence of a 27 Kb coronavirus genome, a novel mechanism of mRNA synthesis that is unique to coronviruses, and many exciting aspects of coronavirus pathogenesis and immunology. Reflecting the growing interest in the preparation of vaccines, several papers also address the issues related to coronavirus vaccines, which is an area new to this symposium. Dr.



Human Coronaviruses


Human Coronaviruses
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Author : Mohamad Hesam Shahrajabian
language : en
Publisher:
Release Date : 2020

Human Coronaviruses written by Mohamad Hesam Shahrajabian and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020 with Coronaviruses categories.


The coronaviruses are ssRNA viruses that infect a wide range of mammalian and avian species; they are important causes of respiratory and enteric disease, encephalomyelitis, hepatitis, serositis and vasculitis domestic animals. In humans coronaviruses are one of several groups of viruses that cause the common cold. The genus Coronavirus together with the genus Torovirus from the family Coronaviridae; members of these two genera are similar morphologically. The Coronaviridae, Arteriviridae, and Roniviridae are within the order Nidovirales. Seven coronaviruses are known to infect humans, three of them are serious, namely, SARS (severe acute respiratory syndrome, China, 2002), MERS (Middle East respiratory syndrome, Saudi Arabia, 2012), and SARS-CoV-2 (2019-2020). SARS is caused by a coronavirus (SARS-CoV) which exists in bats and palm civets in Southern China. Its family is Coronaviridae, and its genus is Coronavirus. The most important groups who are at risk are family members in close contact with cases, health-care workers in close contact with cases, elderly and immune compromised individuals appear at increased risk. MERS-CoV is a zoonotic virus which can lead to secondary human infections. It is the sixth coronavirus that influences human. MERS-CoV is most likely derived from an ancestral reservoir bats. MERS outbreak was found in the Republic of Korea since 2015. Coronavirus entry is initiated by the binding of the spike protein (S) to cell receptors, specifically, dipeptidyl peptidase 4 (DDP4) and angiotensin converting enzyme 2 (ACE2) for MERS-CoV and SARS-CoV, respectively. The genome sequence analysis has shown that SARS-CoV-2 belongs to betacoronavirus genus, which includes Bat SARS-like coronavirus, SARS-CoV and MERS-CoV. On the basis of nucleic acid sequence similarity, the newly identified 2019-nCoV is a betacoronavirus. The RBD portion of the SARS-CoV-2 pike proteins has evolved to effectively target a molecular feature on the outside of human cells called ACE2, a receptor involved in regulating blood pressure. The SARS-CoV-2 spike protein was found so effective at binding the human cells. In SARS-CoV-2, M protein is responsible for the transmembrane transport of nutrient, the bud release and the formation of envelope, S protein, attaching to hose receptor ACE2, including two subunits S1 and S2. These diseases can be considered important models for emerging infectious diseases as it emerged from natural animal reservoirs. Early recognition, prompt isolation and appropriate supportive therapy are the main parameters in combating with these deadly infections.