Curcumin In Health And Disease
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Curcumin In Health And Disease
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Author : Beatrice E. Bachmeier
language : en
Publisher: MDPI
Release Date : 2019-10-11
Curcumin In Health And Disease written by Beatrice E. Bachmeier and has been published by MDPI this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019-10-11 with Medical categories.
The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin’s antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs’ therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.
The Molecular Targets And Therapeutic Uses Of Curcumin In Health And Disease
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Author : Bharat B. Aggarwal
language : en
Publisher: Springer Science & Business Media
Release Date : 2007-08-06
The Molecular Targets And Therapeutic Uses Of Curcumin In Health And Disease written by Bharat B. Aggarwal and has been published by Springer Science & Business Media this book supported file pdf, txt, epub, kindle and other format this book has been release on 2007-08-06 with Medical categories.
The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.
Curcumin In Health And Disease
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Author : Beatrice Bachmeier
language : en
Publisher:
Release Date : 2019
Curcumin In Health And Disease written by Beatrice Bachmeier and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2019 with Electronic books categories.
The plant-derived polyphenol curcumin has been used in promoting health and combating disease for thousands of years. Its therapeutic effects have been successfully utilized in Ayurvedic and Traditional Chinese Medicine in order to treat inflammatory diseases. Current results from modern biomolecular research reveal the modulatory effects of curcumin on a variety of signal transduction pathways associated with inflammation and cancer. In this context, curcumin's antioxidant, anti-inflammatory, anti-tumorigenic, and even anti-metastatic activities are discussed. On the cellular level, the reduced activity of several transcription factors (such as NFkB or AP-1) and the suppression of inflammatory cytokines, matrix degrading enzymes, metastasis related genes and even microRNAs are reported. On functional levels, these molecular effects translate into reduced proliferative, invasive, and metastatic capacity, as well as induced tumor cell apoptosis. All these effects have been observed not only in vitro but also in animal models. In combination with anti-neoplastic drugs like Taxol, kinase inhibitors, and radiation therapy, curcumin potentiates the drugs' therapeutic power and can protect against undesired side effects. Natural plant-derived compounds like curcumin have one significant advantage: They do not usually cause side effects. This feature qualifies curcumin for primary prevention in healthy persons with a predisposition to cancer, arteriosclerosis, or chronic inflammatory diseases. Nonetheless, curcumin is considered safe, although potential toxic effects stemming from high dosages, long-term intake, and pharmacological interactions with other compounds have yet to be assessed. This Special Issue examines in detail and updates current research on the molecular targets, protective effects, and modes of action of natural plant-derived compounds and their roles in the prevention and treatment of human diseases.
The Molecular Targets And Therapeutic Uses Of Curcumin In Health And Disease
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Author : Bharat B. Aggarwal
language : en
Publisher: Springer
Release Date : 2008-11-01
The Molecular Targets And Therapeutic Uses Of Curcumin In Health And Disease written by Bharat B. Aggarwal and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2008-11-01 with Medical categories.
The medicinal uses of Curcumin (also called turmeric) have been known and described for more than 5000 years. A large body of recent research suggests that curcumin is potentially useful in the treatment of inflammatory diseases, through modulation of numerous molecular targets. This is the first monograph to focus on the potential use of curcumin in the treatment of cancer, diabetes, cardiovascular diseases, arthritis, Alzheimer’s, psoriasis and more.
Curcumin And Its Role In Health And Disease
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Author : Kathryn Woltjer
language : en
Publisher:
Release Date : 2023-03-20
Curcumin And Its Role In Health And Disease written by Kathryn Woltjer and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2023-03-20 with categories.
This book contains eight chapters discussing curcumin and its role in health and disease. Chapter One evaluates curcumin's role in cancer prevention. Chapter Two reviews curcumin's function as a natural systemic disease modulator. Chapter Three looks at the effects of curcumin supplantation and exercise training on Alzheimer's disease and age-associated cognitive decline. Chapter Four focuses on the antiviral effects of curcumin, with a special emphasis on COVID-19. Chapter Five examines green extraction techniques for curcumin, synthetic approaches, as well as its anti-inflammatory, anti-oxidant, and anti-neoplastic effects. Chapter Six reviews the possible effects of immune responses to the preventive combined effects of exercise training and curcumin supplementation in chronic disease. Chapter Seven is a mini review of the essential therapeutic effects of curcumin. The eighth and final chapter examines the promises and challenges of curcumin in medical research.
Curcuma Longa And Its Health Effects Volume 2
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Author : Noboru Motohashi
language : en
Publisher:
Release Date : 2020-07-30
Curcuma Longa And Its Health Effects Volume 2 written by Noboru Motohashi and has been published by this book supported file pdf, txt, epub, kindle and other format this book has been release on 2020-07-30 with categories.
Curcumin, which is contained in turmeric in India and surrounding areas, has been widely used for colorants such as curry for thousands of years. Recent studies of curcuminn have reported that curcumin is effective in preventing and treating lifestyle-related diseases such as hypertension, diabetes, dementia, liver disease, heart failure and eye strain. This volume contains the following contents: In Chapter 1, curcumin, also known as diferuloylmethane is a primary and essential constituent of turmeric (Curcuma longa) rhizomes with numerous biological activities. Curcumin was established to benefit in the treatment of inflammatory conditions, metabolic syndrome, pain as well as in controlling inflammatory and degenerative eye conditions including cancers. In addition, curcumin aided in the control of ailments associated with kidneys. These numerous therapeutic benefits of curcumin supplementation were accredited to its potent anti-inflammatory and antioxidant effects. Some of these activities by curcumin were attributed through its interference with aberrant cellular signaling pathways that resulted in many diseases such as cancer, arthritis and other inflammatory diseases. In recent times curcumin is available in multiple formulations including capsules, cosmetics, energy drinks, ointments, soaps and tablets. Curcumin was approved by the US Food and Drug Administration (FDA) as "Generally Recognized As Safe" (GRAS) and curcumin excellent tolerability and safety were established through clinical trials, even at relative high doses. Since 4000 years, turmeric has been used to treat a variety of ailments. Turmeric is used in religious ceremonies as well as textile dyeing owing to its vibrant orange color. In Ayurveda and Chinese traditional medicine (CTM), turmeric is often expended as anti-inflammatory agent in the treatment of digestive and liver ailments, skin diseases including wounds. Turmeric has been consumed in different forms in various countries due to curcumin beneficial effects. In USA, turmeric is used in mustard sauce, cheese, butter, and chips, as a preservative and a coloring agent. In Chapter 2, Curcuma longa L. belongs to the ginger family. It is widely cultivated and distributed in South and Southeast Asia. Besides gastronomic uses, Curcuma is one of the main plants used throughout the folklore medicine such as Ayurveda, Unani, Siddha, and Chinese medicine. To date, traditional medicinal treatments have been increasing worldwide to treat common diseases. Therefore, this chapter focused on the curcuma ́s essential oil beneficial properties. The antifungal and antibacterial activities of curcuma ́s essential oil are highly important due to become natural methods to prevent food deterioration and extend shelf life caused by Aspergillus, Fusarium or Colletotrichum genus. Moreover, Curcuma ́s essential oil exhibits antimicrobial activities against pathogens such as Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans, and Aspergillus niger that cause diverse infections in humankind. According to these properties, Curcuma ́s essential oil may be an ecofriendly alternative to produce antimicrobial and anti-fungicides agents with important industrial applications. Chapter 3, flavanones are one of the most diverse and widespread group belongs to the subclass of flavanoids. They contain hydroxyl and methoxy groups and occupy a prominent position in the plant kingdom due to the wide variety of multi-directional pharmacological properties. The discovery of vital molecules by isolation and synthesis of natural products from medicinal plants has always been a challenge in the field of natural products chemistry. Syzygium samarangense is a famous plant belongs to the family Myrtaceae and widely cultivated and grown thought out India for their edible fruits. Then, here, one of the family Myrtaceae contains diarylheptanoids (curcuminoids). Then, Chapter 3 reviews the isolation and semisynthesis of typical biocomponents other than diarylheptanoids (curcuminoids) for Syzygium samarangense (water apple. wax apple), a family Myrtaceae. The fruit pulp and leaves of water apple is a rich source of phenols, flavonoids, triterpenoids, chalcones, tannins, and several antioxidant compounds and as a result, it is believed to have great potential health benefits and is used in traditional medicine to cure diabetes. Syzygium samarangense was reported to posses antidiabetic activity, antihyperglycemic activity, spasmolytic, antioxidant, and immunomodulatory activity. Basing on the excellent pharmacological properties of Syzygium samarangense, we have selected the stem bark of Syzygium samarangense, extracted with different organic solvents, subjected to acid hydrolysis and then purified by using preparative HPLC. 7-Hydroxy flavanone was isolated and then subjected to semi synthesis by using different substituted isoxazoles and cinnamic acid. The present chapter discusses the isolation of 7-hydroxy flavanone from the stem bark of Syzygium samarangense and also explored the facile synthesis of 7-hydroxyflavanone with isoxazoles and cinnamic acids.
Turmeric For Health
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Author : Britt Brandon
language : en
Publisher: Simon and Schuster
Release Date : 2016-09-02
Turmeric For Health written by Britt Brandon and has been published by Simon and Schuster this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-09-02 with Health & Fitness categories.
Discover the power of turmeric! For centuries, turmeric, the spice that gives curry its yellow color and its distinctive warm and earthy flavor, has been used in eastern medicine traditions as an anti-inflammatory and pain-relieving remedy. Now, new medical studies are confirming this wisdom--and adding to it. Turmeric contains powerful antioxidants, which can help combat chronic life-threatening diseases, including heart disease, certain types of cancer, arthritis, Parkinson's disease, and Alzheimer's disease. It's also an all-natural remedy for common ailments and an effective health and beauty aid. Turmeric for Health provides 100 all-natural solutions that help: Soothe digestive upset Relieve daily aches and pains and reduce inflammation Improve metabolic function and weight loss Promote healthy skin, hair, and nails With Turmeric for Health, you'll discover all the benefits that this simple spice can bring--without dangerous chemicals or costly procedures.
Curcumin
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Author : Jun Sasaki
language : en
Publisher: Nova Science Publishers
Release Date : 2012-05-01
Curcumin written by Jun Sasaki and has been published by Nova Science Publishers this book supported file pdf, txt, epub, kindle and other format this book has been release on 2012-05-01 with Turmeric categories.
Curcumin is a natural product found in the rhizome of Curcuma longa. Ongoing research and clinical trials prove this natural phenolic compound to possess diverse pharmacological potency and is effective as an antioxidant, anti-inflammatory, antimicrobial/antiviral property and is also being considered as a cancer chemo-preventive agent. Topics discussed in this book include the implications of curcumin treatment of central nervous system disease; phosphorylase kinase inhibition in skin disease; PEGylated curcumin; the potential role of curcumin as a chemotherapeutic drug and the pharmaceutical implications of curcumin in the development of drugs for cystic fibrosis pharmacotherapy.
Curcumin Nature S Answer To Cancer And Other Chronic Diseases
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Author : Ajay Goel Ph D
language : en
Publisher: Take Charge Books
Release Date : 2016-03-02
Curcumin Nature S Answer To Cancer And Other Chronic Diseases written by Ajay Goel Ph D and has been published by Take Charge Books this book supported file pdf, txt, epub, kindle and other format this book has been release on 2016-03-02 with Health & Fitness categories.
Curcumin is the answer to cancer and chronic health problems Have you: Been diagnosed with cancer? Had cancer and "recovered" only to fear its recurrence? Had a friend or loved one with cancer? Been diagnosed with diabetes or pre-diabetes? Struggled with your weight? Been depressed? Worried about your memory? Had high blood pressure, high triglycerides, high cholesterol or other signs of heart disease? Had joint pain or arthritis? Had digestive disorders like inflammatory or irritable bowel, chronic constipation or diarrhea or Crohn's disease? Curcumin offers the solution you need to prevent and even reverse these diseases to create a lifetime of vibrant health. Dr. Ajay Goel has spent more than 20 years researching the most effective natural means of combatting cancer and other chronic diseases."
Curcumin And Neurodegenerative Diseases
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Author : Mahendra Rai
language : en
Publisher: Springer
Release Date : 2024-03-09
Curcumin And Neurodegenerative Diseases written by Mahendra Rai and has been published by Springer this book supported file pdf, txt, epub, kindle and other format this book has been release on 2024-03-09 with Medical categories.
This book explores the potential benefits of turmeric, and specifically curcumin, in the treatment and prevention of neurodegenerative diseases. The book covers various aspects of turmeric, including its traditional use in Ayurveda and Chinese medicine, secondary metabolites, curcuminoids, and sesquiterpenoids found in turmeric, as well as the use of nano curcumin in neurodegenerative diseases. It discusses the different ways in which turmeric can be used to treat neurodegenerative diseases, including as a therapy for brain diseases, curcumin-induced neuroprotection in cerebral ischemia, and neural stem cell therapy in combination with curcumin. It also discusses the role of nano curcumin in neurodegenerative diseases, including its potential use in the treatment of Alzheimer's disease. The book provides the scientific evidence behind the use of turmeric and its compounds in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. Overall, this book is an invaluable resource for researchers and healthcare professionals interested in exploring the potential benefits of turmeric and curcumin in the treatment and prevention of neurodegenerative diseases.